The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy
Vol 24, No 1 (2023): VOLUME 24, NUMBER 1, April, 2023

Asparaginase-Induced Acute Necrotizing Pancreatitis Resulting in Chronic Pancreatitis and Pseudocyst in an Adult with Acute Lymphocytic Leukemia

Adiwinata, Randy (Unknown)
Waleleng, Bradley Jimmy (Unknown)
Haroen, Harlinda (Unknown)
Rotty, Linda (Unknown)
Gosal, Fandy (Unknown)
Rotty, Luciana (Unknown)
Hendratta, Cecillia (Unknown)
Lasut, Pearla (Unknown)
Winarta, Jeanne (Unknown)
Waleleng, Andrew (Unknown)
Tendean, Michael (Unknown)

Article Info

Publish Date
10 Apr 2023

Abstract

L-Asparaginase is one of the main chemotherapy regiments for acute lymphocytic leukemia (ALL) management. Acute pancreatitis is one of the serious side effects of l-asparaginase administration and may lead to interruption of chemotherapy cycle. Long term complications may be devastating for patients which include of pseudocyst pancreas and chronic pancreatitis. Asparaginase induced pancreatitis is rare among adult due to the nature of ALL which commonly occurred in children population. The pathophysiology of asparaginase induced pancreatitis is still unclear. Here we present 18-year-old male with ALL and asparaginase induced acute necrotizing pancreatitis which complicated to chronic pancreatitis and pseudocyst. 

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Journal Info
The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy
Website

Abbrev

jghe

Publisher

The Indonesian Society for Digestive Endoscopy

Subject

Medicine & Pharmacology

Description

The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy is an academic journal which has been published since 2000 and owned by 3 Societies: The Indonesian Society of Gastroenterology; Indonesian Association for the Study of the Liver; The Indonesian Society for Digestive ...