cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
Sunny Wangko
Contact Email
sunnypatriciawangko@gmail.com
Phone
+628124455733
Journal Mail Official
sunnypatriciawangko@gmail.com
Editorial Address
eclinic.paai@gmail.com
Location
Kota manado,
Sulawesi utara
INDONESIA
e-CliniC
Published by Universitas Sam Ratulangi
ISSN : 23375949     EISSN : -     DOI : -
Core Subject : Health,
Health Professions
Jurnal e-CliniC (eCl) diterbitkan oleh Perhimpunan Ahli Anatomi Indonesia bekerja sama dengan Fakultas Kedokteran Universitas Sam Ratulangi Manado. Jurnal ini diterbitkan 3 (tiga) kali setahun (Maret, Juli, dan November). Sejak tahun 2016 Jurnal e-CliniC diterbitkan 2 (dua) kali setahun (Juni dan Desember). Jurnal e-CliniC memuat artikel penelitian, telaah ilmiah, dan laporan kasus di bidang ilmu kedokteran klinik.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 1,074 Documents
 84   85   86   87   88 
Terapi Oksigen Hiperbarik Meningkatkan Kualitas Hidup Pasien Glioblastoma Multiforme Stadium Akhir Dinilai Berdasarkan Neurologic Assessment Neuro Oncology Score Djunadi, Hanni; Oley, Maximillian Ch.; Prasetyo, Eko; Hatibie, Mendy; Langi, Fredrik G.
e-CliniC Vol 9, No 2 (2021): e-CliniC
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.v9i2.37098

Abstract

Abstract: Patients with end-stage glioblastoma multiforme (GBM) that cannot be operated or treated with chemotheraphy and radiotheraphy have increased clinical complaints, thus affecting the patients’ quality of lifes (QoL). Hyperbaric oxygen therapy (HBOT) could alters hypoxic condition in tumor tissue with a different cascade from wound healing process. This study was aimed to assess whether the QoL of end-stage GBM patients could improve with the administration of HBOT assessed by decreased clinical complaints based on NANO score. The study was carried out at the Surgery Department of Prof. Dr. R. D. Kandou Hospital Manado, using pre and posttrial design. Each sample was assessed for the NANO score before HBOT, after one time, three times, five times, and 10 times of HBOT. The results showed that there was a change in the NANO score before and after 10 times of HBOT. The decrease in the NANO score occurred more quickly after the therapy. In the last two measurements, the NANO score according to the RVC model decreased from one to two units. The decreased NANO score occurred quite regularly with variations in the score that changed from time to time. In conclusion, HBOT can improve the QoL of patients with end-stage GBM and reduce the NANO score which is an assessment of clinical complaints of the patients.Keywords: glioblastoma multiforme; hyperbaric oxygen therapy; NANO score Abstrak: Penderita glioblastoma multiforme (GBM) stadium akhir yang tidak dapat dilakukan operasi, kemoterapi dan radioterapi memiliki keluhan klinis yang semakin meningkat sehingga memengaruhi kualitas hidup. Terapi oksigen hiperbarik (TOHB) dapat mengubah kondisi hipoksia pada jaringan tumor dengan kaskade yang berbeda dari proses penyembuhan luka. Penelitian ini bertujuan untuk menilai apakah kualitas hidup pasien GBM stadium akhir dapat membaik dengan pemberian TOHB, dinilai dengan menurunnya keluhan klinis berdasarkan NANO score. Penelitian dilakukan di Bagian Bedah RSUP Prof. Dr. R. D. Kandou Manado, dengan menggunakan pre and posttrial design. Pada setiap sampel dilakukan penilaian NANO score sebelum TOHB, setelah satu kali, tiga kali, lima kali, dan 10 kali TOHB. Hasil penelitian mendapatkan adanya perubahan NANO score sebelum TOHB dan setelah 10 kali TOHB. Penurunan NANO score berlangsung lebih cepat pasca terapi tersebut. Dalam dua pengukuran terakhir, NANO score menurut model RVC turun dari satu hingga dua satuan. Pada grafik, hasil penurunan NANO score terjadi cukup beraturan dengan variasi score yang berubah dari waktu ke waktu. Simpulan penelitian ini ialah TOHB dapat meningkatkan kualitas hidup penderita GBM stadium akhir dan menurunkan NANO score yang menjadi penilainan keluhan klinis penderita.Kata kunci: glioblastoma multiforme; terapi oksigen hiperbarik; NANO score
Skin Manifestations due to Arthropod Bites and Stings Feisy P. Matindas; Pieter L. Suling; Nurdjannah J. Niode
e-CliniC Vol. 10 No. 1 (2022): e-CliniC
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.v10i1.37601

Abstract

Abstract: In tropical and subtropical areas, invertebrates that threaten human health are often found inter alia arthropods. Arthropod bites and stings can cause pain and discomfort, severe tissue damage, and even death. This study aimed to determine the skin manifestations caused by arthropod bites and stings. This was a literature review study using two databases, science direct and pubmed.The keywords were arthropods AND bites and stings AND skin manifestation. The results obtained eight articles consisting of four case reports and four research articles. The most common arthropod genus invading human beings were insects and spiders.  Skin manifestations were reported as erythema, urticaria, prurigo, papula, and necrotic tissue. Atopic individual showed allergic reaction that could lead to death. Bee and wasp stings were potential to cause anaphylactic reaction that needed emergency care. Arthropod habitat could influence the invasion level and or location of bites and stings. In Europe and United States, the most frequently found were spider bites meanwhile in Asia, the mosquito bites and bee stings. In conclusion, skin manifestations due to arthropod bites and stings are erythema, urticaria, prurigo, papula, and necrotic tissue. In atopic individual, these bites and stings could lead to deathKeywords: arthropod; bites and stings; skin manifestation Abstrak: Di daerah tropis dan subtropis sering dijumpai hewan invertebrata yang mengancam kesehatan manusia, antara lain golongan artropoda. Gigitan dan sengatan artrropoda dapat menyebabkan rasa sakit dan ketidaknyamanan, kerusakan jaringan yang parah, dan menjadi penyebab beberapa kasus kematian. Penelitian ini bertujuan untuk mendapatkan manifestasi kulit akibat gigitan dan sengatan artropoda. Jenis penelitian ialah suatu literature review dengan menggunakan database science direct dan pubmed. dan kata kunci arthropods AND bites and stings AND skin manifestation. Hasil penelitian mendapatkan delapan literatur, terdiri dari empat laporan kasus dan empat artikel penelitian. Genus artropoda yang paling banyak menginvasi manusia ialah serangga dan laba-laba. Manifestasi kulit yang sering dijumpai berupa eritema, urtikaria, prurigo, papula, dan nekrosis jaringan. Pada individu atopik sering dijumpai reaksi alergi bahkan mengarah kepada kematian. Manifestasi oleh sengatan lebah dan tawon juga berpotensi menyebabkan reaksi anafilaksis yang memerlukan penanganan segera. Habitat artropoda juga berpengaruh terhadap tingkat invasi dan atau lokasi dari gigitan dan sengatan. Di benua Eropa dan Amerika, kasus yang sering dijumpai berupa gigitan laba-laba sedangkan di wilayah benua Asia ialah gigitan nyamuk dan sengatan lebah. Simpulan penelitian ini ialah manifestasi kulit akibat gigitan dan sengatan artropoda berupa eritema, urtikaria, prurigo, papula, dan nekrosis jaringan. Pada individu yang atopik gigitan dan sengatan artropoda dapat berakibat fatal.Kata kunci: artropoda; gigitan dan sengatan; manifestasi kulit
Relationship between Competence, Motivation, and Leadership with Performance of Nutrition Workers at Public Health Centers Meiny O. Manumpil; Nova H. Kapantow; Martha M. Kaseke
e-CliniC Vol. 10 No. 1 (2022): e-CliniC
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.v10i1.37591

Abstract

Abstract: Achieving good performance needs to be supported by qualified human resources. Factors that affect performance include competence, motivation, and leadership. This study aimed to determine the relationship between competence, motivation, and leadership with the performance of health workers at public health center. This was a quantitative study. The population consisted of all nutrition workers at public health centers in Manado totaling 48 people; all of them were samples of this study. Data were analyzed by using the Pearson product moment test and the multiple linear regression test. The results showed that the mean of competence variable was 19.69; of motivation variable was 103.2; of leadership variable was 44.19; and of performance variable was 103.02. The Pearson product moment test resulted in p=0.020 for the  correlation between competence and performance; p=0.012, for the correlation between motivation and performance; and p=0.200, for the correlation between leadership and performance. The multiple linear regression test showed that motivation had the strongest relationship with performance (p=0,018). In conclusion, there are significant relationships between competence and motivation with performance. Motivation has the strongest relationshipwith performance.Keywords: competence; motivation; leadership; performanceAbstrak: Pencapaian kinerja yang baik perlu didukung oleh sumber daya manusia yang berkualitas. Faktor yang memengaruhi kinerja di antaranya faktor kepemimpinan, faktor pribadi meliputi motivasi, disiplin, keterampilan, faktor sistem, dan faktor situasional atau lingkungan kerja. Penelitian ini bertujuan untuk mengetahui hubungan antara kompetensi, motivasi, dan kepemimpinan dengan kinerja petugas gizi di puskesmas. Jenis penelitian ialah kuantitatif.Populasi ialah seluruh petugas gizi di puskesmas Kota Manado.berjumlah 48 orang dengan populasi total sebagai sampel. Analisis statistik yang digunakan ialah uji Pearson product moment dan uji regresi linier berganda. Hasil penelitian mendapatkan rerata kompetensi 19,69, rerata motivasi 103,2, rerata kepemimpinan 44,19, dan rerata kinerja 103,02. Hasil uji Pearson productmoment menunjukkan nilai p=0,020 untuk korelasi antara kompetensi dengan kinerja; p=0,012 untuk korelasi antara motivasi dengan kinerja; dan p=0,200 untuk korelasi antara kepemimpinan dengan kinerja. Hasil uji regresi linier berganda menunjukkan bahwa variabel motivasi yang paling erat hubungannya dengan kinerja. Simpulan penelitian ini ialah terdapat hubungan bermakna antara kompetensi dan motivasi dengan kinerja petugas gizi di puskesmas. Mottivasi memiliki hubungan yang paling erat dengan kinerja.Kata kunci: kompetensi; motivasi; kepemimpinan; kinerja
Ocular Manifestations in Systemic Lupus Erythematosus Ade J. Nursalim; Enricco H. Mamuaja; Wenny Supit; Elbetty Simanjuntak; Stevanus J. Loho; Christian M. Komaling
e-CliniC Vol. 10 No. 1 (2022): e-CliniC
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.v10i1.37631

Abstract

Abstract: Systemic Lupus erythematosus (SLE) is a connective tissue disorder that attacks several organs of the body, including the eyes. Ocular manifestation of this disease could be a sign of SLE activity and can cause decreased vision function to blindness. SLE can also affect extraocular tissue, anterior segment, posterior segment, and the optic nerve. The assessment of eye abnormalities that may arise due to SLE should alert the ophthalmologists. Treatment can be either local or systematic. The systematic management includes antimalarial agent, corticosteroids, immunomodulators, and biological agents. Cooperation among divisions and other medical fields is needed in the treatment of SLE. This paper aims to present the ocular manifestations of SLE, and is expected to improve the diagnostic quality, especially in terms of early diagnosis and appropriate treatment.Keywords: systemic lupus erythematosus; ocular manifestation Abstrak: Sistemik lupus eritematosus merupakan kelainan jaringan ikat yang yang menyerang beberapa organ tubuh termasuk mata. Gangguan pada mata ini dapat menjadi tanda keaktifan SLE, dan menyebabkan penurunan fungsi penglihatan hingga kebutaan. SLE dapat memengaruhi jaringan ekstraokular, segmen anterior, segmen posterior, dan saraf optik. Pengkajian kelainan mata yang mungkin timbul akibat SLE ini perlu mendapat perhatian oleh dokter mata. Tatalaksana dapat berupa tatalaksana lokal maupun sistemik. Tatalaksana sistemik berupa obat-obatan anti malaria, kortikosteroid, imunomodulator, dan agen biologis. Kerjasama antar divisi dan bidang kedokteran lainnya diperlukan dalam penanganan SLE. Tulisan ini bertujuan untuk menge-mukakan manfestasi klinis SLE pada mata dan diharapkan dapat meningkatkan kualitas diagnostik terutama dalam hal diagnosis dini dan tatalaksana yang cepat dan tepat.Kata kunci: sistemik lupus eritematosus; manifestasi okular
Evaluasi Hasil Labioplasti Menggunakan Skor CLEFT-Q Deki, Feldy; Hatibie, Mendy; Oley, Maximillian Ch.; Langi, Fredrik G.
e-CliniC Vol 9, No 2 (2021): e-CliniC
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.v9i2.35939

Abstract

Abstract: Application of CLEFT-Q score instrument in the assessment of surgical outcomes for cleft lip and/or cleft palate based on patient reports is still relatively new. This study was aimed to establish the normative value of the Indonesian version of CLEFT-Q score in post-cleft lip surgery patients and to differentiate the results of cleft lip surgery according to the score based on the type of cleft, age, and sex. This was a preliminary study using the Indonesian CLEFT-Q instrument. Patients were interviewed for filling out the Indonesian version of CLEFT-Q after surgery. There were 75 samples in this study. Significant results were found in the association between age and CLEFT-Q score (p<0.05 and R>0.35). Variable selection for multi-variable analysis included cleft type and age in the model, where age alone indicated a significant relationship. The linear regression model involved the relationship between CLEFT-Q scores and gender, age, and cleft type as covariates. The correlation shown was classified as having moderate strength (R=0.46) for all covariates. In conclusion, the normative value of the Indonesian version of CLEFT-Q score with an approach to post-cleft lip surgery patients got a value that was in accordance with the highest standard in the literature, namely 91. The results of cleft lip surgery according to the Indonesian version of CLEFT-Q score based on the type of cleft, age and gender can be applied according to the literature.Keywords: cleft lip; cleft palate; cleft lip and palate; Indonesian version of CLEFT-Q Abstrak: Penerapan skor CLEFT-Q dalam penilaian luaran operasi bibir sumbing dan/atau langit-langit terbelah berdasarkan laporan pasien masih relatif baru. Penelitian ini bertujuan untuk mene-gakkan nilai normatif skor CLEFT-Q berbahasa Indonesia pada pasien pasca operasi bibir sum-bing serta membedakan hasil operasi bibir sumbing menurut skor tersebut berdasarkan tipe cleft, usia, dan jenis kelamin. Jenis penelitian ialah studi pendahuluan penggunaan CLEFT-Q berbahasa Indonesia. Pasien diwawancarai untuk melakukan pengisian CLEFT-Q berbahasa Indonesia setelah operasi. Hasil penelitian mendapatkan total 75 sampel. Hasil bermakna ditemukan pada hubungan antara usia dan skor CLEFT-Q (p <0,05 dan R > 0,35). Seleksi variabel untuk analisis multivariabel mengikutsertakan tipe cleft dan usia di dalam model, dan variabel usia saja yang mengindikasikan adanya hubungan bermakna (95% CI 1,15-2,33; p=0,006). Model regresi linear melibatkan hubungan antara skor CLEFT-Q dengan jenis kelamin, usia, dan tipe cleft sebagai kovariat dan mendapatkan korelasi kekuatan sedang (R=0,46) untuk semua kovariat. Simpulan penelitian ini ialah nilai normatif skor CLEFT-Q berbahasa Indonesia dengan pendekatan terhadap pasien pasca operasi bibir sumbing mendapatkan nilai yang sesuai dengan standar tertinggi pada kepustakaan yaitu 91. Hasil operasi bibir sumbing menurut skor CLEFT-Q berbahasa Indonesia berdasarkan tipe cleft, umur dan jenis kelamin dapat diterapkan sesuai kepustakaan.Kata kunci: cleft lip; cleft palate; cleft lip and palate; skor CLEFT-Q berbahasa Indonesia
Analysis of Chest Tube Scars on the Use of Conventional versus Knotless Methods Claudia Loho; Mendy Hatibie; Adrian Tangkilisan; Wega Sukanto; Fredrik G. Langi
e-CliniC Vol. 10 No. 1 (2022): e-CliniC
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.v10i1.36927

Abstract

Abstract: Removal of chest tube is a one of the most distressing and frustrating experience for patients. Moreover, it has a tendency of scar formation. A relatively new method has been developed using a type of suture without knots (knotless). Assessment of scar is an objective and subjective method performed by using patient and observer scar assessment scale (POSAS). This study was aimed to assess the scars formed due to chest tube removal using conventional and knotless sutures. This was a controlled trial design. The Mann-Whitney test was used to compare the PSOAS scores of scars formed due to conventional and knotless sutures performed by patients and observers after three months, and obtained a p-value of less than 0.05. In conclusion, scar formation due to knotless suture is more acceptable for patients compared to conventional suture among chest tube removal wounds; therefore, the knotless suture can be a cosmetically alternative for wound closure management. Keywords: chest tube; scar tissue; knotless suture; conventional suture Abstrak: Pelepasan chest tube merupakan hal yang menyakitkan dan pengalaman yang membuat frustasi bagi pasien. Selain itu, tindakan ini berpeluang menyebabkan pembentukan jaringan parut. Telah dikembangkan metode baru dengan material jahitan baru yang tidak perlu disimpul. Penilaian jaringan parut dapat berupa penilaian obyektif dan subyektif dengan menggunakan Patient and Observer Scar Assessment Scale (POSAS). Penelitian ini bertujuan untuk menilai jaringan parut akibat pelepasan chest tube antara penjahitan metode konvensional dan knotless. Desain penelitian ialah controlled trial. Penilaian PSOAS baik dari pasien, observer, atau keduanya dilakukan tiga bulan kemudian terhadap jaringan parut yang terbentuk akibat penggunaan kedua metode. Perbandingan hasil skor PSOAS dianalisis dengan uji Mann-Whitney yang mendapatkan nilai p<0,05. Simpulan penelitian ini ialah pembentukan jaringan parut pada metode knotless lebih akseptabel bagi pasien dibandingkan metode konvensional. Hal ini dapat menjadi salah satu metode alternatif penutupan luka chest tube dengan hasil yang lebih dapat diterima.Kata kunci: chest tube; jaringan parut; metode knotless; metode konvensional
Inguinal Hernia in Infant Matthew A Kumaat; Harsali Lampus; Nathaniel Pali
e-CliniC Vol. 10 No. 2 (2022): e-CliniC
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.v10i2.37617

Abstract

Abstract: Inguinal hernia in infant is a condition of protrusion of the intestinal organs due to thepatency of processus vaginalis. The ratio of incidence between male and female infants isapproximately 8:1. The incidence of inguinal hernia ranges from 1-5% in children and full-terminfants, whereas in premature infants there is a significant increase in the number, which is around30%. Clinical manifestations that can occur in infants with inguinal hernias are the appearance ofa lump when straining, crying, coughing, or sneezing, patient could look restless because of thepain and discomfort. The diagnosis of inguinal hernia can be made by history taking, physicalexamination, and supporting examination. Management of inguinal hernia is by surgery, can bean open herniotomy or laparoscopy.Keywords: inguinal hernia; infant Abstrak: Hernia inguinalis pada bayi merupakan kondisi penonjolan organ intestinal akibatadanya patensi prosesus vaginalis. Perbandingan rasio kejadian antara anak laki-laki dan perempuankurang lebih sekitar 8:1. Insidensi hernia inguinalis berkisar 1-5% pada anak dan bayi cukupbulan, sedangkan pada bayi prematur terdapat kenaikan angka yang bermakna yaitu sekitar 30%.Manifestasi klinis yang dapat terjadi pada anak dengan hernia inguinalis adalah timbulnyabenjolan pada saat mengedan, menangis, batuk, atau bersin, anak terlihat gelisah karena nyeri danrasa tidak nyaman. Penegakan diagnosis hernia inguinalis dapat dilakukan dengan anamnesis,pemeriksaan fisik, dan pemeriksaan penunjang. Tatalaksana hernia inguinalis ialah denganherniotomi terbuka atau laparoskopi.Kata kunci: hernia inguinalis; bayi
Management and Outcome of Pediatric Appendicitis in COVID-19 Era Novia D. Yantika; Harsali Lampus; Angelica M. J. Wagiu
e-CliniC Vol. 10 No. 2 (2022): e-CliniC
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.v10i2.37668

Abstract

Abstract: The COVID-19 pandemic has an impact on health services including the management of appendicitis in children both infected and infected with COVID-19. Change in the management of appendicitis in children during the COVID-19 pandemic is still controversial regarding the outcomes arising from this management. This study aimed to determine the management and outcome of appendicitis in children infected and uninfected with COVID-19 during the COVID-19 pandemic. This was a literature review study using databases of PubMed, ClinicalKey and Google Scholar and keywords, as follows: (Management paediatric appendicitis and COVID) AND (outcome paediatric appendicitis and COVID). The results obtained 19 articles. There was a modification in the management of pediatric patients with appendicitis during the COVID-19 pandemic, which was an increase in the use of open appendectomy procedures, especially in COVID-19 positive patients and non-operative management, however, some still maintain the laparoscopic procedure. Meanwhile, the outcome of the management showed that there was no significant difference related to the occurrence of complications, the length of stay in patients with surgery, and the high failure rate in patients with non-operative management, therefore, interval appendectomy was needed. In conclusion, there is a modification in the management of appendicitis in children during the COVID-19 pandemic with insignificant outcome in the operative action and failure related to the non-operative management.Keywords: management; outcome; pediatric appendicitis; COVID-19 Abstrak: Pandemi COVID-19 memberi dampak pada pelayanan kesehatan termasuk manajemen apendisitis pada anak baik yang terinfeksi maupun tidak terinfeksi COVID-19. Perubahan manajemen apendisitis pada anak selama pandemi COVID-19 masih menjadi kontroversial terkait dengan luaran yang terjadi akibat manajemen tersebut. Penelitian ini bertujuan untuk mengetahui manajemen dan luaran apendisitis pada anak yang terinfeksi maupun tidak terinfeksi COVID-19 selama pandemi COVID-19. Penelitian ini berbentuk literature review menggunakan database dari PubMed, ClinicalKey dan Google Scholar dengan kata kunci (Management paediatric appendicitis and COVID) AND (outcome paediatric appendicitis and COVID). Hasil penelitian mendapatkan 19 artikel. Terjadi modifikasi dalam manajemen pasien anak dengan apendisitis selama pandemi COVID-19, yaitu peningkatan dalam penggunaan prosedur apendektomi terbuka terutama pada pasien positif COVID-19 dan manajemen non-operatif, namun beberapa diantaranya tetap memper-tahankan dilakukannya prosedur laparoskopi. Luaran dari manajemen yang dilakukan menunjukkan bahwa tidak didapatkan perbedaan bermakna terkait terjadinya komplikasi, masa rawat inap pada pasien dengan tindakan operatif, dan tingginya tingkat kegagalan pada pasien dengan manajemen non-operatif; oleh karena itu apendektomi interval masih diperlukan. Simpulan penelitian ini ialah adanya modifikasi dalam manajemen apendisitis pada anak selama pandemi COVID-19 dengan luaran yang tidak berbeda bermakna dalam hal tindakan operatif dan kegagalan terkait manajemen non-operatif.Kata kunci: manajemen; luaran; apendisitis pada anak; COVID-19
Efficacy of Paracetamol Compared to Ibuprofen on Closure of Patent Ductus Arteriosus in Premature Infants Alviolita P. Rondonuwu; Johnny L. Rompis; David S. Waworuntu
e-CliniC Vol. 10 No. 2 (2022): e-CliniC
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.v10i2.37701

Abstract

Abstract: Patent ductus arteriosus (PDA) is a congenital heart disease caused by failure of the ductus arteriosus to close immediately after birth. PDA can cause hemodynamic disturbances in premature infants as well as increased morbidity and mortality. Therefore, it needs to be closed immediately. Closuring of the PDA can use ibuprofen as a cyclooxygenase (COX) inhibitor, however, there are potential side effects. Paracetamol can be used as an alternative that acts as a peroxidase (POX) inhibitor with few side effects. This study aimed to compare the efficacy of paracetamol and ibuprofen on PDA closure in premature infants. This was a literature review, using four databases, such as Pubmed, ClinicalKey, Cochrane and ScienceDirect. The keywords used were paracetamol AND ibuprofen AND patent ductus arteriosus AND preterm AND newborn. Selection with inclusion and exclusion criteria obtained 13 articles. Paracetamol was as effective as ibuprofen for PDA closure therapy in premature infants. Paracetamol was safer than ibuprofen due to ibuprofen’s side effects. In conclusion, paracetamol is as effective as ibuprofen and is safer to be used in PDA closure therapy in premature babies.Keywords: paracetamol; ibuprofen; patent ductus arteriosus; preterm; newborn Abstrak: Patent ductus arteriosus (PDA) adalah penyakit jantung kongenital akibat gagalnya ductus arteriosus untuk menutup segera setelah lahir. PDA dapat menyebabkan gangguan hemodinamika pada bayi prematur, serta meningkatkan morbiditas dan mortalitas sehingga perlu segera ditutup. Penutupan PDA dapat menggunakan ibuprofen sebagai penghambat cyclo oxygenase (COX), namun terdapat efek samping potensial yang ditimbulkan. Parasetamol dapat digunakan sebagai alternatif yang bekerja menghambat peroksidase (POX) dengan sedikit efek samping. Penelitian ini bertujuan untuk membandingkan efikasi parasetamol dan ibuprofen untuk penutupan PDA pada bayi prematur. Penelitian ini berbentuk literature review, menggunakan empat database yaitu Pubmed, ClinicalKey, Cochrane dan ScienceDirect. Kata kunci yang digunakan yaitu paracetamol AND ibuprofen AND patent ductus arteriosus AND preterm AND newborn. Hasil seleksi dengan kriteria inklusi dan eksklusi mendapatkan 13 literatur. Hasil penelitian mendapatkan bahwa parasetamol sama efektif dengan ibuprofen untuk terapi penutupan PDA pada bayi prematur. Parasetamol lebih aman dibandingkan ibuprofen akibat efek samping yang ditimbulkan. Simpulan penelitian ini ialah parasetamol sama efektif dengan ibuprofen serta lebih aman untuk digunakan sebagai terapi penutupan PDA pada bayi prematur.Kata kunci: parasetamol; ibuprofen; patent ductus arteriosus; prematur; bayi
Risk Factors Related to Hypertension in Children Shyella E. Ngantung; Adrian Umboh; Jeanette I. Ch. Manoppo
e-CliniC Vol. 10 No. 2 (2022): e-CliniC
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.v10i2.37708

Abstract

Abstract: Hypertension is a serious health problem, not only because of its increasing incidence but also due to its morbidity and mortality. Although children often experience an increase in blood pressure, it is very difficult and even cannot be determined early. Therefore, the increase in blood pressure can persist into adulthood and results in hypertension and coronary heart disease. This is influenced by several risk factors that can support the occurrence of hypertension in children. This study aimed to determine the risk factors associated with the incidence of hypertension. This was a literature review study using two databases namely Pubmed and Google Scholar and the keywords were risk factor AND hypertension AND children. The results obtained that there was a relationship between hypertension with nutritional status (obesity), excessive salt consumption, poor physical activity, smoking behavior, poor sleep quality, family history of hypertension, and male sex. In conclusion, there are a variety of risk factors related to hypertension, and obesity is the dominant one.Keywords: risk factor; hypertension; children Abstrak: Hipertensi merupakan masalah kesehatan yang serius, bukan saja karena angka kejadian-nya yang meningkat melainkan karena morbiditas dan mortalitas yang diakibatkannya. Anak seringkali mengalami peningkatan tekanan darah akan tetapi sangat sulit bahkan tidak dapat ditentukan sejak dini sehingga peningkatan tekanan darah dapat menetap hingga dewasa dan mengakibatkan hipertensi dan penyakit jantung koroner. Hal tersebut dipengaruhi oleh beberapa faktor risiko yang dapat mendukung terjadinya hipertensi pada anak. Penelitian ini bertujuan untuk mengetahui faktor risiko yang berhubungan dengan kejadian hipertensi. Jenis penelitian ini ialah suatu literature review dengan menggunakan dua database yaitu Pubmed and Google Scholar dengan kata kunci risk factor AND hypertension AND children. Hasil penelitian mendapatkan bahwa terdapat hubungan antara hipertensi dengan status gizi lebih (obesitas), konsumsi garam berlebih, aktivitas fisik kurang, perilaku merokok, kualitas tidur buruk, riwayat hipertensi keluarga, dan jenis kelamin laki-laki. Simpulan penelitian ini ialah terdapat berbagai factor risiko yang berhubungan dengan kejadian hipertensi dengan obesitas sebagai faktor risiko yang dominan.Kata kunci: faktor risiko; hipertensi; anak

Page 86 of 108 | Total Record : 1074

 84   85   86   87   88 

Filter by Year

2013 2026


Reset
Filter By Issues
All Issue Vol. 14 No. 1 (2026): e-CliniC Vol. 13 No. 2 (2025): e-CliniC Vol. 13 No. 1 (2025): e-CliniC Vol. 12 No. 3 (2024): e-CliniC Vol. 12 No. 2 (2024): e-CliniC Vol. 12 No. 1 (2024): e-CliniC Vol. 11 No. 3 (2023): e-CliniC Vol. 11 No. 2 (2023): e-CliniC Vol. 11 No. 1 (2023): e-CliniC Vol. 10 No. 2 (2022): e-CliniC Vol. 10 No. 1 (2022): e-CliniC Vol 9, No 2 (2021): e-CliniC Vol 9, No 1 (2021): e-CliniC Vol 8, No 2 (2020): e-CliniC Vol 8, No 1 (2020): e-CliniC Vol 7, No 2 (2019): e-CliniC Vol 7, No 1 (2019): e-CliniC Vol 6, No 2 (2018): Jurnal e-CliniC (eCl) Vol 6, No 1 (2018): Jurnal e-CliniC (eCl) Vol 5, No 2 (2017): Jurnal e-CliniC (eCl) Vol 5, No 1 (2017): Jurnal e-CliniC (eCl) Vol 4, No 2 (2016): Jurnal e-CliniC (eCl) Vol 4, No 1 (2016): Jurnal e-CliniC (eCl) Vol 3, No 3 (2015): Jurnal e-CliniC (eCl) Vol 3, No 2 (2015): Jurnal e-CliniC (eCl) Vol 3, No 1 (2015): Jurnal e-CliniC (eCl) Vol 2, No 3 (2014): Jurnal e-CliniC (eCl) Vol 2, No 2 (2014): Jurnal e-CliniC (eCl) Vol 2, No 1 (2014): Jurnal e-CliniC (eCl) Vol 1, No 3 (2013) Vol 1, No 2 (2013): Jurnal e-CliniC Vol 1, No 1 (2013) More Issue