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Contact Name
Sunny Wangko
Contact Email
sunnypatriciawangko@gmail.com
Phone
+628124455733
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sunnypatriciawangko@gmail.com
Editorial Address
eclinic.paai@gmail.com
Location
Kota manado,
Sulawesi utara
INDONESIA
e-CliniC
ISSN : 23375949     EISSN : -     DOI : -
Core Subject : Health,
Jurnal e-CliniC (eCl) diterbitkan oleh Perhimpunan Ahli Anatomi Indonesia bekerja sama dengan Fakultas Kedokteran Universitas Sam Ratulangi Manado. Jurnal ini diterbitkan 3 (tiga) kali setahun (Maret, Juli, dan November). Sejak tahun 2016 Jurnal e-CliniC diterbitkan 2 (dua) kali setahun (Juni dan Desember). Jurnal e-CliniC memuat artikel penelitian, telaah ilmiah, dan laporan kasus di bidang ilmu kedokteran klinik.
Articles 1,074 Documents
Management of Crush Injury’s Complications Using Hyperbaric Oxygen Therapy: Case Series Arikalang, Patrick S.; Hatibie, Mendy J.; Oley, Maximillian C.; Noersasongko, Albertus D.; Suharso, Tommy
e-CliniC Vol. 12 No. 2 (2024): e-CliniC
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.v12i2.46847

Abstract

Abstract: Crush injury occurs due to an external trauma mechanism that directly affects the skin, muscle, and bone tissue. Crush injuries can involve several parts of the body at the same time. When accompanied by handling, wound healing in crush injury can be long-term, so that it can affect the function of the patient. Various complications that can occur ranging from secondary infection, necrosis, recurrent bleeding, to compartment syndrome. We reported serial cases of crush injury with various clinical presentations and complications, varying in the age range of 16-65 years. All four patients were given multiple managements, such as open reduction external fixation and extensive debridement. There were complications such as secondary infection and delay in the wound healing process in patients who did not on time for follow-up. The four patients received additional treatment in the form of wound dressings hyperbaric oxygen therapy (HBOT) with 5-10 90-minute sessions under 2.4 ATA pressure for 10 consecutive days. Follow-up was carried out again within a period of one month to compare the wound condition before and after HBOT. The clinical condition was getting better, marked by the formation of granulation tissue. The state of hyperoxia in HBOT accelerated the inflammatory process and angiogenesis during the wound healing process characterized by the eradication of bacteria in the wound tissue and accelerated neovascularization formation. In conclusion, adequate therapy, wound dressing, and patient compliance affect patient outcome. Moreover, the addition of hyperbaric oxygen therapy has shown to accelerate the wound healing process and restore the patient's limb function. Keywords: crush injury; hyperbaric oxygen therapy; oxygen; wound healing
Keakuratan FNAB pada Limfadenitis Tuberkulosis di Kelenjar Getah Bening Leher di Manado Ijong, Jessie I.; Lumintang, Nico
e-CliniC Vol. 12 No. 2 (2024): e-CliniC
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.v12i2.46849

Abstract

Abstract: Tuberculous lymphadenitis is the most common type of extrapulmonary tuberculosis (TB). Fine needle biopsy aspiration (FNAB) is an initial diagnostic method to evaluate lymph node enlargement in the neck This study aimed to evaluate the accuracy of FNAB in tuberculous lymphadenitis in neck lymph nodes in Manado. This was is a retrospective and descriptive study using medical record data on the use of FNAB examination in patient with a history of lymph node enlargement years 2017-2018. The results obtained 160 FNAB samples with clinical lymph node enlargement in the neck; 86 samples (54%) with TB lymphadenitis, nine samples (6%) were suspected as TB lymphadenitis, and 65 samples (40%) were not TB lymphadenitis The incidence in women (61%) was higher than in men (39%). TB lymphadenitis was most common in women aged <19 years and men aged 20-30 years. In conclusion, FNAB remains an important option as one of the diagnostic supporting tools for lymph node enlargement especially to confirm the diagnosis of tuberculous lymphadenitis in the neck. Keywords: fine needle biopsy aspiration; tuberculous lymphadenitis; cytopathological diagnosis   Abstrak: Limfadenitis tuberkulosis (TB) merupakan bentuk TB ekstrapulmoner yang tersering. Fine needle biopsy aspiration (FNAB) ialah metode diagnostik awal untuk mengevaluasi pembesaran kelenjar getah bening di leher. Penelitian ini bertujuan untuk mengetahui keakuratan FNAB pada limfadenitis tuberkulosis di kelenjar getah bening leher di Manado. Jenis penelitian ialah deskriptif retrospektif menggunakan data rekam medik penggunaan pemeriksaan FNAB pada pasien yang memiliki riwayat pembesaran kelenjar getah bening di leher di Laboratorium Patologi Anatomi RSUP Prof R. D. Kandou Manado.tahun 2017-2018. Hasil penelitian mendapatkan 160 sampel FNAB dengan klinis pembesaran pada leher; 86 sampel (54%) dengan hasil FNAB limfadenitis TB, sembilan sampel (6%) dicurigai sebagai limfadenitis TB, dan 65 sampel (40%) bukan limfadenitis TB. Kejadian pada perempuan (61%) lebih tinggi daripada laki-laki (39%). Limfadenitis TB tersering pada perempuan berusia <19 tahun dan laki-laki 20-30 tahun. Simpulan penelitian ini ialah sampai saat ini FNAB tetap menjadi pilihan sebagai salah satu alat penunjang diagnostik untuk evaluasi pembesaran kelenjar getah bening terutama dalam menentukan limfadenitis TB di leher. Kata kunci: fine needle biopsy aspiration; limfadenitisis tuberculosis; diagnostik sitopatologi
Primary Closure of Gastric Perforation Using Seromuscular Omentum Insertion: A Case Report Kalitouw, Ferry; Salem, Billy; Sugito, Brian
e-CliniC Vol. 12 No. 2 (2024): e-CliniC
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.v12i2.46850

Abstract

Abstract: Gastric perforation is the most common disease and a surgical emergency with high morbidity and mortality; therefore, early and precise management is needed. However, no consensus has been accepted regarding the best surgical treatment for gastric perforation closure so far. Although surgery methods are varied, laparotomy, and omental patch repair are still the gold standard. The risk of leakage after primary closure accompanied by omentopexy is still common, resulting high morbidity and mortality. This study aimed to discuss about the modified method by means of primary closure with seromuscular omentum insertion in a gastric perforation case. We modified the usual method using primary closure with seromuscular omentum insertion, to get the best way for perforation closure and reduced risk of leakage. After a week of surgical perforation closure, the patient was discharged and further observation resulted in no leakage. In conclusion, modified method by using primary closure with seromuscular omentum insertion in gastric perforation has good result without any leakage and recurrence. Keywords: gastric perforation; omentum; primary closure
Small Lymphocytic Lymphoma Presenting as Breast Mass: A Rare Case Report Manginstar, Christian; Merung, Marselus A.; Saleh, Denny; Merung, Marcella
e-CliniC Vol. 12 No. 2 (2024): e-CliniC
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.v12i2.46852

Abstract

Abstract: Primary breast lymphoma is rare and it accounts for around 0.5% of malignant breast neoplasms. Small lymphocytic lymphoma (SLL) is a subtype of non-Hodgkin lymphoma originating from a B-cell lineage. This report presents a case of primary SLL of the breast with lung metastasis that had excellent clinical response. We reported a 67-year-old female complained a right breast mass that suddenly appeared after she got massage on her right left arm. The mass was swollen and painless with no systemic complications. The specimen was submitted to histopathology department and it revealed small diffuse lymphocytic lymphoma. Chest X-ray showed a lung metastasis. The patient was then treated with CHOP regimens (Cyclophosphamid, Doxorubicin, Vincristin, and Prednison) and the clinical result was excellent. The side effects of the medication were minimal. In conclusion, primary breast lymphocytic lymphoma is rare and this case highlights the differential diagnosis for a painless breast mass. The treatment must be individualized and multimodal, with chemotherapy being the most accepted treatment. Keywords: breast lymphoma; breast mass; malignancy
Medical Rehabilitation in Patient with Cerebral Palsy Spastic Diplegic GMFCS IV MACS I CFCS IV EDACS II Rondonuwu, Gloria; Gessal, Joudy; Angelina, Chelsy
e-CliniC Vol. 12 No. 2 (2024): e-CliniC
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.v12i2.46884

Abstract

Abstract: Children with cerebral palsy are present with three types of motor problems. The major disturbances in muscle tone, balance, strength, and selectivity are directly related to damage of the central nervous system. Treatment programs encompass physical and behavioral therapy, pharmacologic and surgical treatments, mechanical aids, and management of associated medical conditions. In physical, occupational, speech, and behavioral therapies, the goals include enhancing patient and caregiver interactions while providing family support. We reported a female, 7-year-old, with cerebral palsy spastic diplegic GMFCS IV MACS I CFCS IV EDACS II. The patient was treated with USD intensity 1 watt/cm2, frequency 3.3 MHz in 5 minutes and continuous stretching in four extremity for 10 minutes each. It showed improvement from the popliteal angle assessment and MAS score, therefore, additional invasive therapy, such as botox injection, might be not needed in the meantime. Stiffness in lower extremities especially at gastrocnemius muscle was treated with ESWT energy of 0.15mJ/mm2; total shots dose 1500 shocks per each treated muscle (gastrocnemius); frequency 4 Hz. The patient presented with lumbar hyperlordotic and anterior pelvic tilt, and also tended to sway posteriorly during standing and walking, resulting poor protection reaction on the anterior side. It will be beneficial to add abdominal core and hip extensor strengthening exercise into the program. For walking aids, we considered about using anterior walker or posterior walker. However, since the patient was 4 years old and could not take complex instruction, it might become challenging to modify the exercise protocol. Regular daily stretching was beneficial for the home program and should be continued. Referral to surgery was not required at this moment due to no joint contracture. Keywords: cerebral palsy; motor problem; gait rehabilitation
Korelasi antara Kadar Kalsidiol (25-Oh) dan Rasio Netrofil-Limfosit dengan Keganasan Nodul Tiroid Bogar, Bryan D.; Lumintang, Nico; Tandililing, Sherly; Wariki, Windy M.
e-CliniC Vol. 12 No. 2 (2024): e-CliniC
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.v12i2.48492

Abstract

Abstract: Thyroid malignancy has shown the highest annual incidence rate. Vitamin D deficiency (serum 25-hydroxyvitamin D levels) is one of the risk factors for thyroid malignancy. The neutrophil-lymphocyte ratio (NLR) reflects the balance between pro-tumor inflammatory response and anti-tumor immune response. This study aimed to investigate the relationship between serum 25-hydroxyvitamin D levels, NLR, and thyroid nodule malignancy. This was an observational and analytical study with cross-sectional design. Samples were patients with thyroid nodules admitted to Prof. Dr. R. D. Kandou Hospital, Manado, form August 2022 to March 2023. The results obtained a total of 46 patients with thyroid malignancy that  met the inclusion criteria. The patient characteristics were predominantly female (82.6%), with a mean age of 50.2 ± 14.74 years, normal thyroid hormone status (82.6%), mean serum 25-hydroxyvitamin D levels of 32.25 ng/mL, mean NLR of 5, and papillary carcinoma as the most common malignancy (43.48%). Spearman's correlation analysis revealed a significant association between thyroid malignancy and serum 25-hydroxyvitamin D levels (r =-0.501, p=0) as well as NLR (r 0.376, p=0.01). In conclusion, serum 25-hydroxyvitamin D levels and NLR can be used as indicators for predicting thyroid nodule malignancy. Keywords: thyroid malignancy; 25-hydroxyvitamin D; neutrophil-lymphocyte ratio   Abstrak: Keganasan tiroid mengalami peningkatan angka kejadian tertinggi pertahun. Kekurangan vitamin D (kadar kalsidiol) merupakan salah satu faktor risiko terjadinya keganasan tiroid. Rasio netrofil limfosit (RNL) mencerminkan keseimbangan antara respon inflamasi protumor dan respon imun antitumor. Penelitian ini bertujuan untuk mengevaluasi hubungan antara kadar 25-hydroxyvitamin D serum dan RNL dengan keganasan nodul tiroid. Jenis penelitian ialah analitik observasional dengan desain potong lintang. Sampel penelitian ialah pasein dengan nodul tiroid yang dirawat di RSUP Prof. Dr. R. D. Kandou Hospital, Manado, sejak Agustus 2022 s/d Maret 2023. Hasil penelitian mendapatkan 46 pasien dengan keganasan tiroid yang memenuhi kriteria. Karakteristik sampel tebanyak ialah jenis kelamin perempuan (82,6%), rerata usia (50,2±14,74 tahun), status hormon tiroid normal (82,6%), rerata kadar 25-hydroxyvitamin D 32,25 ng/mL, rerata RNL 5, dan jenis keganasan karsinoma papiler (43,48%). Uji analisis Spearman menunjukkan keganasan tiroid secara bermakna berhubungan dengan kadar kalsidiol (r=-0,501, p=0), dan RNL (r=0,376, p=0,01). Simpulan penelitian ini ialah kadar 25-hydroxyvitamin D serum dan RNL dapat digunakan sebagai indikator untuk memrediksi keganasan nodul tiroid. Kata Kunci: keganasan tiroid; 25-hydroxyvitamin D; rasio netrofil-limfosit
Pengaruh Pemberian Bifosfonat terhadap Pasien dengan Fraktur Tulang Panjang Pasca Open Reduction Internal Fixation (ORIF) Ijong, Jessie I.; Sunaryo, Haryanto; Rawung, Rangga
e-CliniC Vol. 12 No. 3 (2024): e-CliniC
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.v12i3.49019

Abstract

Abstract: Clinical, radiographic, and laboratory tests can be used to evaluate bone healing of fractured bone. This study aimed to analyze the impact of bisphosphonate medication on the prognosis of patients receiving open reduction internal fixation (ORIF) for long bone fractures. This was a randomized controlled trial study. Information was gathered prospectively, meaning that osteocalcin level was checked on each patient who fulfilled the study's eligibility requirements. The non-parametric Mann-Whitney test or the bivariate T test was the employed statistical test. Linear regression test was applied to multiple variables. The results showed that the average age of men and women was 36 years, with a 6:4 gender ratio. Patients were divided into two groups, namely the bisphosphonate and the control groups The average pre-ORIF osteocalcin level was 12 ng/mL. In comparison to controls, patients taking oral bisphosphonates had a slightly higher mean (12.9 vs 11.5 ng/mL; p=0.017). This difference maintained following ORIF, when the mean osteocalcin level in the bisphosphonate group increased to roughly 20 ng/mL whereas it was only 16 ng/mL in the control group (p=0.002). The callus index of the patients pre-ORIF did not significantly differ from the mediolateral or anteroposterior aspects. After ORIF, differences started to be noticed where both methods of measuring the callus index produced identical results for patients on oral bisphosphonates (median 1.2) and controls (median 1.1). In conclusion, administration of sodium bisphosphonate has an influence on patients experiencing long bone fractures and open reduction internal fixation (ORIF). Keywords: long bone fracture; osteocalcin; callus; bisphosphonate   Abstrak: Penyembuhan tulang (union) dapat dinilai dari pemeriksaan klinis, radiologis, dan laboratorium. Penelitian ini bertujuan untuk mengevaluasi pengaruh pemberian bifosfonat terhadap luaran pasien fraktur tulang panjang pasca open reduction internal fixation (ORIF). Jenis penelitian ialah studi randomized controlled trial. Informasi dikumpulkan secara prospektif, yaitu setiap pasien yang memenuhi kriteria penelitian diambil datanya dan diperiksa kadar osteokalsin. Uji bivariat yang digunakan ialah uji T atau uji non parametrik Mann–Whitney, serta uji multivariat menggunakan regresi linear. Hasil penelitian mendapatkan rasio laki-laki : perempuan sebesar 6:4 dengan rerata usia 36 tahun, yang dibagi atas kelompok bifosfonat dan kelompok kontrol.  Kadar osteokalsin pra ORIF secara umum sekitar 12 ng/mL. Nilai rerata tersebut sedikit lebih tinggi pada kelonmpok bifosfonat dibandingkan kontrol (12,9 vs 11,5 ng/mL; p = 0,017). Perbedaan tersebut terus bertahan pasca ORIF di mana rerata kadar osteokalsin mencapai sekitar 20 ng/mL pada kelompok bifosfonat sedangkan kontrol 16 ng/mL (p=0,002). Indeks kalus para pasien sampel pra ORIF relatif tidak berbeda baik dilihat dari aspektus anteroposterior maupun mediolateral. Perbedaan mulai terdeteksi pasca ORIF di mana kedua pendekatan penilaian indeks kalus tersebut memberikan hasil yang sama untuk pasien dengan bifosfonat oral (median 1,2) maupun kontrol (median 1,1). Simpulan penelitian ini ialah pemberian natrium bifosfonat memiliki pengaruh terhadap pasien fraktur tulang panjang dengan open reduction internal fixation (ORIF). Kata kunci: fraktur tulang panjang; osteokalsin; kalus; bifosfonat
Penilaian Kemampuan Prognostic Nutritional Index Memrediksi Lama Penyembuhan Luka Operasi Paska Tindakan Laparotomi pada Pasien Kanker Kolorektal Suatan, Regina; Tjandra, Ferdinand; Salem, Billy; Langi, Frederik G.
e-CliniC Vol. 12 No. 2 (2024): e-CliniC
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.v12i2.51744

Abstract

Abstract: In colorectal cancer, surgical resection is the main curative therapeutic modality for localized, non-metastatic colorectal cancer at any age with good performance status and controlled comorbidities. Nutritional status is known to be a very important factor in the treatment of all types of surgery including preoperative and postoperative aspects. This study aimed to assess the ability of prognostic nutritional index (PNI) to predict the healing time of surgical wounds after laparotomy in patients with colorectal cancer. Samples were patients with colorectal cancer that underwent laparotomy at Prof. Dr. R. D. Kandou Hospital, Manado. The results showed that mean age of patients was 55 years and the mean body mass index (BMI) was 22. Patients with comorbids were 18.2%. The most common duration of wound healing according to Southampton wound grade system was grade 0 (63.6%), followed by grade 1 (18.2%), grade 2 (4.5%), and grade 3 (13.6%). The Spearman test showed a positive correlation between pre-operative PNI and duration of wound healing (r=0.582), and the 2-tailed significancy of 0.000. In conclusion, prognostic nutritional index can predict the duration of post-laparotomy wound healing in colorectal cancer patients. Keywords: colorectal cancer;  prognostic nutritional index; wound healing   Abstrak: Pada kanker kolorektal reseksi pembedahan merupakan modalitas terapi utama yang bersifat kuratif untuk stadium non metastasis yang masih terlokalisasi pada usia berapapun dengan status performance yang masih baik dan komorbiditas terkontrol. Status gizi diketahui menjadi faktor yang sangat penting dalam penanganan seluruh jenis bedah termasuk aspek pre operatif dan post operatif. Penelitian ini bertujuan untuk menilai kemampuan prognostic nutritional index (PNI) dalam memrediksi lama penyembuhan luka operasi paska tindakan laparotomi pada pasien dengan kanker kolorektal. Sampel penelitian ialah pasien dengan kanker kolorektal yang menjalani laparatomi di RSUP Prof. Dr. R. D. Kandou Manado. Hasil penelitian mendapatkan rerata usia pasien ialah 55 tahun dan rerata indeks massa tubuh (IMT) ialah 22. Pasien yang memiliki penyakit penyerta sebesar 18,2%. Lama penyembuhan luka operasi menurut (Southampton Wound Grade System) terbanyak ialah grade 0 (63,6%), diikuti grade 1 (18,2%), grade 2 (4,5%), dan grade 3 (13,6%). Hasil uji korelasi Spearman terhadap korelasi antara PNI pre-OP dengan lama penyembuhan luka operasi bernilai positif 0,582, dengan nilai Sig. (2-tailed) sebesar 0,000. Simpulan penelitian ini ialah prognostic nutritional index dapat memrediksi lama penyembuhan luka operasi paska tindakan laparotomi pada pasien kanker kolorektal. Kata kunci: kanker kolorektal; prognostic nutritional index; penyembuhan luka operasi
Perbandingan antara Skor ALBI, Child-Pugh, dan MELD dalam Memrediksi Kejadian Post Hepatectomy Liver Failure pada Pasien Karsinoma Hepato-seluler di RSUP Prof. Dr. R. D. Kandou Manado Martino, Celine; Tendean, Michael; Mambu, Toar D. B.; Langi, Fredrik G.
e-CliniC Vol. 12 No. 2 (2024): e-CliniC
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.v12i2.51814

Abstract

Abstract: Hepatocellular carcinoma (HCC) accounts for nearly 90% of hepatic malignancies. ALBI (Albumin-Bilirubin), Child-Pugh, and MELD (Model for End-stage Liver Disease) scores can predict the incidence of Post Hepatectomy Liver Failure (PHLF) in patients undergoing liver resection. This study aimed to obtain the comparison of ALBI, Child-Pugh, and MELD scores in predicting the incidence of PHLF in patients undergoing liver resection. This was a descriptive and retrospective study using medical records of Prof. Dr. R. D. Kandou Hospital, Manado, from 2019 to early 2022. The results obtained 54 patients who had undergone liver resection. The Child Pugh, ALBI, and MELD scores had similar ability in predicting the prognosis of PHLF. The MELD score had the sensitivity dan specifity of 64% and 81%, and the accuracy of 78% meanwhile the ALBI dan Child-Pugh scores had sensitivity less than 50%. In conclusion, compared with the ALBI and Child Pugh scores, the MELD score has higher sensitivity. Keywords: hepatocellular carcinoma; ALBI score; Child-Pugh score; MELD score; post hepatectomy liver failure   Abstrak: Karsinoma hepatoseluler (HCC) menyumbang hampir 90% kasus keganasan pada hepar. Skor ALBI, Child-Pugh dan MELD (Model for End-stage Liver Disease) dapat memrediksi kejadian post hepatectomy liver failure (PHLF) pada pasien yang menjalani reseksi hepar. Penelitian ini bertujuan untuk membandingkan skor ALBI, Child-Pugh dan MELD dalam memrediksi kejadian PHLF pada pasien yang menjalani reseksi hepar. Jenis penelitian ialah deskriptif retrospektif menggunakan data rekam medis di RSUP Prof. Dr. R. D. Kandou Manado dari tahun 2019 sampai awal tahun 2022. Hasil penelitian mendapatkan 54 pasien yang telah menjalani reseksi hati. Skoring Child-Pugh, ALBI dan MELD memiliki kemampuan serupa dalam menentukan prognosis PHLF. Skor  MELD menunjukkan sensitivitas dan spesifisitas berturut-turut sebesar 64% dan 81%, dengan akurasi 78% sedangkan skor ALBI dan Child-Pugh memiliki sensitivitas di bawah 50%. Simpulan penelitian ini ialah dibandingkan dengan skor ALBI dan Child-Pugh, skor MELD memiliki sensitivitas lebih tinggi dalam memrediksi kejadian PHLF. Kata kunci: karsinoma hepatoseluler; skor ALBI; skor Child-Pugh; skor MELD; post hepatectomy liver failure
Development and Validation of a Scoring System for Predicting Complications of Pancreatitis in Patients with Post Endoscopic Retrograde Cholangiopancreatography Melatunan, Leonard A.; Mambu, Toar D. B.; Tendean, Michael; Langi, Fredrik G. L.
e-CliniC Vol. 12 No. 3 (2024): e-CliniC
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.v12i3.51815

Abstract

Abstract: Post ERCP pancreatitis (PEP) is the most common complication of endoscopic retrograde cholangiopancreatography (ERCP) with significant morbidity and mortality rates. Several factors are associated with the occurrence of PEP. There are several methods available to predict such complications, however, they are not yet valid and need some improvement. This study aimed to obtain a scoring system to predict the incidence of post ERCP pancreatitis. This was a retrospective study using medical records of patients who underwent ERCP at Prof. Dr. R. D. Kandou Hospital from 2017 to 2023. The results obtained 372 patients as samples. Gender, previous history of ERCP, cannulation attempt ≥5 times, pancreatogram, double wire technique, EPBD, and pancreatic duct stent failure were independently associated with PEP and included in the model, which achieved AUC 96.7%, sensitivity 95.0% and specificity 89.8%. In conclusion, a predictive scoring system to assess the incidence of post ERCP pancreatitis (PEP) using seven risk factors related to patient, procedure, operator, and technique is used to aid early identification of PEP and therapeutic intervention. This scoring system is simple and easy to use, and has high area under curve (AUC), sensitivity, and specificity. Keywords: endoscopic retrograde cholangiopancreatography (ERCP); post ERCP pancreatitis; scoring system

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