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Jurnal Farmasi Sains dan Komunitas

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Published by Universitas Sanata Dharma

ISSN : 16935683 EISSN : 25277146 DOI : https://doi.org/10.24071/

Core Subject : Health,

Medicine & Pharmacology

Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community / J Pharm Sci Community) firstly published in 2003, is a peer-reviewed, open access scientific journal that publishes research articles, review articles, as well as short communication in various pharmaceutical fields, including Pharmaceutical Technology and Pharmaceutics, Pharmaceutical Analysis, Medicinal Chemistry, Pharmacology and Toxicology, Pharmaceutical Biology, Community Pharmacy, and Clinical Pharmacy.

Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)

Articles 247 Documents

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UJI AKTIVITAS ANTIOKSIDAN MENGGUNAKAN RADIKAL 1,1-DIFENIL-2- PIKRILHIDRAZIL DAN PENETAPAN KANDUNGAN FENOLIK TOTAL FRAKSI ETIL ASETAT EKSTRAK ETANOL BUAH ANGGUR BALI (Vitis vinifera L.) Mikhael Gustandy; C.J. Soegihardjo
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 10, No 2 (2013)
Publisher : Sanata Dharma University

Abstract: This research was conducted to determine the antioxidant activity of ethyl acetatfraction of extract of Balinesse grape (Vitis vinifera L.) using free radical and determine the totalphenolic content. Balinesse grape was extracted with ethanol and then fractionated using ethylacetate. Free radical scavenging activity was tested by measuring the DPPH radical scavengingactivity. Total phenolic content was determined using the Folin-Ciocalteau method measured theconcentration of phenolic content in gallic acid total equivalents using unit's mg/g. The mean IC50value for DPPH radical scavenging activity of the ethyl acetat fraction of ethanolic extract ofBalinesse grape was found to be 36.55 0.09 g/mL. The phenolic content was ranging from 3.23 0.02 mg gallic acid equivalents per gram of ethyl acetat fraction of ethanolic extract ofBalinesse grape.Keywords: antioxidants, Balinesse grape (Vitis vinifera L.), fraction of ethyl acetat, DPPH, totalphenolic content.

EFFECTS OF INTERPROFESSIONAL COLLABORATION PROGRAM IN COMMUNITY ON THE PERCEPTION OF PHARMACY AND MEDICAL STUDENTS Christianus Heru Setiawan; Rita Suhadi; Phebe Hendra; Fenty Fenty; Dita Maria Virginia; Gregorius Bhaskara Wikanendra
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 17, No 2 (2020)
Publisher : Sanata Dharma University

Cardiovascular disease is the highest cause of mortality in Indonesia. One of the factors that causes the disease is low level of health awareness, including healthy lifestyle and health control. Improving public health awareness can be done by providing health education in collaboration with interprofessional health services. A collaboration involving students from various health-related disciplines aims to build good collaboration in the future after the corresponding students become health workers. This study is quasi-experimental. Students from health-related disciplines, especially pharmacy and medical students, were authorized to work directly in health screening and to provide education to the community. Students perceptions on the Interprofessional Collaboration (IPC) program were explored through Student Perceptions of Physician-Pharmacist Interprofessional Clinical Education (SPICE) questionnaire, which were given before and after the community project. Among 87 SPICE questionnaires, 78 questionnaires filled in completely were collected from pharmacy and medical students. The results of the questionnaire showed good perceptions before and after activities in the community with mean scores of 4.46 (0.35) and 4.5 (0.37) respectively. Wilcoxon test results found no significant difference on the total SPICE scores before and after the activity (P .05). One item from the SPICE questionnaire, which was the seventh item related to understanding the role of other professionals in the interdisciplinary team, had a significant increase (P .05).

TINGKAT KEPATUHAN ANTIHIPERTENSI DAN PENGONTROLAN TEKANAN DARAH PASIEN RAWAT JALAN RS PKU MUHAMMADIYAH BANTUL, YOGYAKARTA YANG MENDAPATKAN BRIEF COUNSELING-5A DAN SMS MOTIVASIONAL Zukhruf Ginanjar Saputri; Akrom Akrom; Endang Darmawan
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 13, No 2 (2016)
Publisher : Sanata Dharma University

Antihypertensive therapy requires adherence therapy to achieve therapeutic targets such as controlling blood pressure both systolic and diastolic blood pressure. Pharmacists in counseling interventions have been developed in the form of brief Counseling - 5A and SMS reminders. But the relationship between adherence and blood pressure control is still studied and both of them are related to many factors that can affect. The aim of this study was to determine the relationship of the level of compliance antihypertensive therapy and control of blood pressure (systolic and diastolic) hypertension patients in outpatient PKU Muhammadiyah Bantul, Yogyakarta who get Brief counseling - 5A and SMS motivation.Patients who met the inclusion criteria were divided into 2 groups, the treatment group (n = 30) who received Brief counseling - 5A and SMS motivation, and the control group (n = 30) who received usual care (conventional counseling). Data were collected by interviews using questionnaires compliance of Morisky Medication Adherence Scale (MMAS), the value of blood pressure is taken from the medical record. Correlation between level of adherence and blood pressure control have been analyzed using Fisher test. The results showed the treatment group with categories adherent patients (n=25) was increase in blood pressure control by 36.67% compared with the control group of patients adherent category (n=6) only 6.67% that has control of the blood pressure on post study. In contrast to patient with adherent category, who had uncontrolled blood pressure are 46.67% (treatment group) compared to the control group 13.33% on the post study. Patients categories of non-adherent but is having control of blood pressure showed 3.33% (treatment group) and 26.67% (control group) on the post study. Although the rate of compliance in the treatment group was higher than control group on the second visit, but there was no significant relation between the level of compliance and controlling blood pressure both in control group (p=1.000) and intervention group (p=0.622) on the second visit (post). The rate of compliance and blood pressure control of patients with hypertensive was low. There were many factors such as poor of knowledge, drugs side effect, poly pharmacy, which related with level of compliance. There was no correlation between antihypertensive compliance and blood pressure control in hypertensive patients ambulatory PKU Muhammadiyah Bantul Hospital, who get Brief counseling 5A and SMS motivation. Therefore it is necessary to do further research to identify factors that influence to improve patients awareness in the management of hypertension.

THE DIFFERENCE IN THE TOTAL CHOLESTEROL/HDL-C RATIO IN TYPE-2 DM PATIENTS WITH DIABETIC ULCERS AND WITHOUT DIABETIC ULCERS IN BETHESDA HOSPITAL YOGYAKARTA Devina Sagitania; Purwoadi Sujatno; Fenty Fenty
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 15, No 1 (2018)
Publisher : Sanata Dharma University

Diabetes mellitus (DM) is one of the diseases that annually shows an increase. An increase of DM prevalence will follow the increasing diabetic ulcers complication. Cholesterol could influence to create ulcer through atherosclerosis process. Ratio of total cholesterol/HDL is an important predictor to detect early risk of vascular complication in type 2 DM patients that can manifest as diabetic ulcers. This study aims to know whether there is any difference in the Total Cholesterol/HDL-C Ratio in type-2 DM patients with diabetic ulcers and without diabetic ulcers. This study was an analytic observational with cross-sectional approach. Data collection was done using the purposive sampling with a sample size of 30 patients of diabetes mellitus with diabetic ulcers and 30 patients without diabetic ulcers. The data were analyzed by Mann-Whitney. The median results in Total cholesterol/HDL-C ratio between Type-2 DM patients with diabetic ulcers and without diabetic ulcers were 6.025 and 3.680 respectively. The median of cholesterol total/HDL-C ratio Type-2 DM patients with diabetic ulcers was higher than those without diabetic ulcers. Mann-Whitney showed the value of P = 0.000, so that this study found a significant difference. In conclusion, the ratio of total cholesterol/HDL-C in type-2 DM patients with diabetic ulcer was significantly higher than type-2 DM patients without diabetic ulcers in Bethesda Hospital, Yogyakarta.

EVALUASI DAMPAK PENERAPAN AUTOMATED DISPENSING MACHINE TERHADAP DISPENSING ERROR DI FARMASI RAWAT JALAN INSTALASI FARMASI RUMAH SAKIT BETHESDA YOGYKARTA Purwoadi Sujatno; Rizaldy Taslim Pinzon; Andreasta Meliala
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 13, No 1 (2016)
Publisher : Sanata Dharma University

Dispensing error is not uncommon in the medication proccess. Otomatisation of outpatient pharmacy services decrease the incidence of dispensing error, as well as improving the efficiency of picking, packing and labeling process. Since August 2014 an automated dispensing machine was installed in outpatient pharmascy Bethesda Hospital Yogyakarta, integrated with electronic prescribing and hospital information system. The objective of the study was to evaluate the impact of automated dispensing machine on the dispensing error at outpatient pharmacy Services using before and after study method. The procentage of drugs deliver by automated dispensing machine at the third and sixth month of implementation was 46% and 59%. Failure mode and effeect analysis of dispensing process done before the implementation, and the integration with electronic prescription and hospital information system, as well as the development of smart pack is the key of successed. The average of medications picked after the implementation of automated dispensing machine was (37,915.33 3,160.12), higher than before implementation (36,812.67 2,890.81), but not significant. The average of dispensing error after implementation (15,67 6,28) was reduced significantly (p0,05) than before (50.33 34.47). The most frequent type of dispensing error were wrong quantity dispensed, wrong drug dispensed and wrong strength dispensed. The implementation of automated dispensing machine significantly reduce the incidence of dispensing error. Further investigaation needed to know the incidence of dispesning error cause by the machine and manual and factors that influenced.

STRATEGI PEMERIKSAAN LABORATORIUM ANTIHIV Woro Umi Ratih
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 9, No 2 (2012)
Publisher : Sanata Dharma University

Abstract: Human Immunodeficiency Virus (HIV) infection has increased significantly in recentyears. The virus continues to spread in all the countries. There are some strategies and programsto control HIV infection by activities carried out individually or groups. HIV testing technologiesare needed for use in diagnostic testing. Data from diagnostic testing may be used as a source ofsurveillance information. Rapid Diagnostic Test (RDT) and ELISA with various reagents are thecurrent diagnostic testing procedures. It is important to select reagents to get the good results.Keywords : HIV, testing, diagnostic

PROFILE OF LYCOPENE UV-SPECTRA OF LACTIC ACID BACTERIA FERMENTED MILK-TOMATO PASTE Isnaeni Isnaeni; Nailatul Hidayah; Utari Ardiningdyah; Izza Rahmi Hidayah
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 16, No 1 (2019)
Publisher : Sanata Dharma University

Lycopene is one of the famous ingredients in tomatoes, because of its important role as a potent anti-oxidant. Besides being consumed as fresh fruit, tomato paste can be combined with probiotic fermented milk to increase its health benefits. Probiotics are lactic acid bacteria (LAB), which when consumed in sufficient quantities will benefit health. Probiotic fermented milk is reported to have various properties including anti-microbial, antioxidant, immunomodulatory and anti-cancer, so the combination with tomato paste is expected to increase its benefits for health. This research aimed to study the effect of probiotic fermented milk on the content of tomato paste lycopene. Lactobacillus acidophillus, Lactobacillus bulgaricus, and Lactobacillus casei were used as mixed probiotic cultures. It was found that at the ratio of 2:8 for the LAB fermented milk and tomato paste, the highest lycopene drive was obtained by spectrophotometric measurement at 663, 645, 505, and 453 nm. Determination of the lycopene content was performed according to the Nagata and Yamashita simple methods. In addition, the lycopene content in the LAB fermented milk-tomato paste was greater than the content in the tomato paste without fermented milk addition and was tested stable after storage for 14 days.

ANALISIS FARMAKOEKONOMI PERESEPAN ANTIBIOTIKA CEFTRIAXONE DAN CEFTAZIDIME PADA PASIEN BEDAH SESAR DI RUMAH SAKIT PANTI RINI YOGYAKARTA Maria Wisnu Donowati
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 10, No 2 (2013)
Publisher : Sanata Dharma University

Abstract: The raising of cesarean section had leaded the abuse of antibiotic prescribing in orderto minimize the wound or urethra infection that came in the caesarean surgery. Pharmaceuticalcare oriented had push pharmacist to care more about patients drug use to increase quality oflive. The aim of this research is to identify the total hospital service cost and calculate totalantibiotic cost, total drug and prescribtion. The data are collected through medical records andhospital service cost of 145 Panti Rini hospital cesarean section patients in 2003. Normality andhomogenity test are using computer programme, ? 95%. The most patient were 25-30 years old,first gestational fist partum and non aborts, cephalopelvic disproportion indication and havingthird class in hospital services. Ceftazidime in Pharodime and Ceftriaxone in Tricefin are themost cephalosphorin third generation that had been used among other antibiotics. Total hospitalcost that must be paid by the third class cesarean section patients are same, Rp. 820,974 in a day.The average of total drug and medical equipment cost and total antibiotics cost are different.Total drug and medical equipment cost in a day by using Pharodime is cheaper Rp. 33,903 thanTricefin. Total antibiotics cost in a day by using Pharodime is cheaper Rp. 34,663 thanTricefin.Keywords: pharmacoeconomic, antibiotic, prescription.

THE USE OF INTERNET AND SOCIAL MEDIA FOR DRUG INFORMATION SERVICES IN PHARMACIES IN YOGYAKARTA PROVINCE: A STUDY OF ASTHMA CARE Fajar Ira Juwita; Aris Widayati; Enade Perdana Istyastono
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 17, No 1 (2020)
Publisher : Sanata Dharma University

Industrial revolution 4.0 is the process of digitizing the industry that leds health services in the era of application of Information and Communication Technology (ICT) called e-health. The application of ICT in Pharmacy is known as e-pharmacy. The role of pharmacists in Drug Information Services by utilizing ICTs has an effect on e-health literacy which ultimately supports the success of patient therapy. This is very important for patients with chronic diseases who are receiving treatment for a long time, one of which is asthma patients. Therefore, this study aims to explore pharmacist perceptions regarding the use of the internet and social media for drug information services, with a case study of services in asthma patients. This research is descriptive with a qualitative approach. Data is collected by interviews using an interview guide that has been validated in a professional judgment. Interviews were conducted with pharmacist participants who provided pharmacy services to asthma patients, who were selected purposively in March to July 2019. Data from interviews were transcribed verbatim, then a thematic analysis was performed. Ethical clearance has been obtained under number 945/ C.16/ FK/ 2019. The results of the study mention the use of the internet and social media indicate the potential capabilities of pharmacists in health services and also the challenges of transformation to the role of pharmacists in the e-pharmacy era. This study also mentions the urgency of establishing regulations regarding e-pharmacy that is driven by the violation from the internet and social media use. Improvement of ICT infrastructure in the pharmacy field as well as the pharmacist's contribution on the provision of drug information for chronic diseases, including asthma, are urgently required.

VIRTUAL SCREENING CAMPAIGNS ON ISOFLAVONES TO DISCOVER POTENT CYCLOOXYGENASE-2 INHIBITORS Enade Perdana Istyastono
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 14, No 2 (2017)
Publisher : Sanata Dharma University

By employing recently published structure-based virtual screening (SBVS) to identify potent cyclooxygenase-2 (COX-2) inhibitors, all isoflavones collected by ZINC15 database were virtually screened. There were 3371 isoflavones in ZINC15 database and 1356 compounds out of them met the Lipinskis rule of 5. Notably, only 3 isoflavones out of those 1356 compounds were identified as potent COX-2 inhibitors.

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Contact Name
Florentinus Dika Octa Riswanto

Contact Email
editorial.jpsc@usd.ac.id

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Journal Mail Official
editorial.jpsc@usd.ac.id

Editorial Address
Faculty of Pharmacy, Universitas Sanata Dharma, Indonesia

Location
Kab. sleman,

Daerah istimewa yogyakarta

INDONESIA