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Florentinus Dika Octa Riswanto
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Jurnal Farmasi Sains dan Komunitas
Published by Universitas Sanata Dharma
ISSN : 16935683     EISSN : 25277146     DOI : https://doi.org/10.24071/
Core Subject : Health,
Medicine & Pharmacology
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community / J Pharm Sci Community) firstly published in 2003, is a peer-reviewed, open access scientific journal that publishes research articles, review articles, as well as short communication in various pharmaceutical fields, including Pharmaceutical Technology and Pharmaceutics, Pharmaceutical Analysis, Medicinal Chemistry, Pharmacology and Toxicology, Pharmaceutical Biology, Community Pharmacy, and Clinical Pharmacy.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 247 Documents
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Design, Formulation, and Evaluation of Vitamin C Tablets Using Co-Processed Excipient Combination of Jackfruit Seed Starch and Avicel®️ PH 101 Rahmayanti, Mayu; Dewi, Tanaya Jati Dharma; Aktifa, Ana Fadilia; Paramitha, Sella; Nikmah, Rahayu Hikmatul; Septianshar, Lumen Muzaidi
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 22, No 2 (2025)
Publisher : Sanata Dharma University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24071/jpsc.008319

Abstract

Tablet is a popular pharmaceutical dosage form among the public. One method of making tablets is direct compression. This method must consider the flow properties and compressibility of the excipients. But many excipients do not meet these criteria, leading to the alternative use of co-processed excipients of jackfruit seed starch and avicel®️ PH 101. This research aims to determine the physical characteristics of direct compression vitamin C tablets using co-processed excipient of PBN-A (Jackfruit Seed Starch and Avicel®️ PH 101) with varying ratios of 1:3, 3:1, and 1:1. The research methods include powder preparation, powder evaluation, tablet compression, and physical evaluation of tablet. Descriptive and statistical data analysis using one-way ANOVA. The research results show that tablets exhibit favorable physical characteristics in F1, but F2 and F3 show suboptimal hardness and friability values. The statistical analysis results indicate a significant difference with a p-value of (0.000) and post-hoc tests explain that these significant differences are particularly noticeable between F1 and F2, K1, and K2. This study concludes that vitamin C tablets using co-processed excipients of PBN-A with ratios of 1:3, 3:1, and 1:1 exhibit good physical characteristics in all evaluations, except for the hardness and friability of F2 (3:1) and the hardness of F3 (1:1).
Optimization Formula and SPF Test of Lotion from Essential Oil of Patchouli Leaves (Pogostemon cablin Benth.) Fazariana, Anjaly Rizkya; Sani K, Fathnur; Maharini, Indri
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 22, No 2 (2025)
Publisher : Sanata Dharma University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24071/jpsc.008439

Abstract

An increase in the ultraviolet (UV) index poses severe health risks by inducing harmful effects on the skin, such as sunburn, erythema, skin darkening, premature ageing, and skin cancer. These risks are mitigated through sunscreens with high Sun Protection Factor (SPF) values (15). Natural sources of high SPF include patchouli leaf essential oil, which contains flavonoids. Flavonoid compounds with double bonds can absorb UV-A and UV-B rays, protecting against their harmful effects. The purpose of this study was to find the best formula and observe its impact on the physical characteristics of the preparation and SPF activity. Formula optimization used Design Expert software 13 with the simplex lattice design method. The optimized variables were TEA and stearic acid as emulsifying agents. The results of the optimum formula composition consisted of 4% TEA and 5% stearic acid. The optimum skin protection lotion preparation has a yellow color, a distinctive smell of patchouli oil, a semi-solid shape and a thick texture. The pH parameters of 7.7±0.09, adhesion of 2.34±0.06 seconds, spreadability of 6.85±0.02 cm and viscosity of 4503.3±219.39 Cp. Patchouli leaf essential oil and lotion have ultra-category SPF values with oil SPF value of 27.86±1.07 and lotion preparation of 27.65±1.75 preparation is also homogeneous with pH parameters of 7.7±0.09, adhesion of 2.34±0.06 seconds, spreadability of 6.85±0.02 cm and viscosity of 4503.3±219.39 Cp. Patchouli leaf essential oil and lotion have ultra-category SPF values with oil SPF value of 27.86±1.07 and lotion preparation of 27.65±1.75.
The Relationship Between Knowledge and Behavior Toward Antibiotic Stewardship Among Healthcare Workers at Referral Hospital, West Borneo Fitaloka, Fahira Amanda; Mardhia, Mardhia; Liana, Delima Fajar; Mahyarudin, Mahyarudin; IH, Hariyanto
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 22, No 2 (2025)
Publisher : Sanata Dharma University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24071/jpsc.009974

Abstract

Irrational use of antibiotics is currently still a major health problem in the world. Worldwide around 50% of medicines are sold, distributed, and given to patients inappropriately. Irrational use of antibiotics can trigger antibiotic resistance. Knowledge and behavior regarding antibiotic stewardship are important in preventing antibiotic resistance. This cross-sectional research was conducted to determine the relationship between knowledge and behavior regarding antibiotic stewardship among healthcare workers. This study's 58 respondents were general practitioners/dentists, specialist doctors/dentists, and pharmacists. The instrument used in this study was a valid and reliable questionnaire. The data analysis used was univariate analysis and Spearman analysis with IBM SPSS Statistics 26 and significance set as p0.05. In this study, the results showed that the majority of respondents worked as specialist doctors/dentists (53.44%), aged in the range 26-35 years (36.20%), of the type female (58.62%), have work experience for more than 10 years (39.65%) and all of the surveyed respondents have good knowledge and behavior (100%). Spearman’s rank analysis showed no significant relationship between knowledge and antibiotic stewardship behavior (p0.05). The high level of expertise of respondents does not significantly affect the level of behavior because it can influence several factors, both internal and external. Further study is needed to identify other factors influencing antibiotic stewardship and rational use of medicine.
Analysis of the Relationship Between Providing Drug Information, Medication Adherence, and Glycemic Control in Type 2 Diabetes Outpatients at the North Denpasar Health Center Ratnasari, Pande Made Desy; Yuliawati, Agustina Nila; Prasetya, Anak Agung Ngurah Putra Riana; Krisnamahesswari, Ni Luh Koming
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 22, No 2 (2025)
Publisher : Sanata Dharma University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24071/jpsc.009708

Abstract

Medication adherence among patients with type 2 diabetes mellitus (T2DM) continues to be a difficult challenge. Providing drug information (PDI) at health centers can enhance medication adherence and help patients achieve glycemic control. A cross-sectional study was conducted in February-April 2024 at the North Denpasar Health Center. Inclusion criteria were patients 18 years old either with or without comorbidities, receiving the same antidiabetic treatment for ≥3 months. Exclusion criteria were patients who withdrew from the study, changed their care, or had unstable health conditions. Medication adherence data were collected using the Probabilistic Medication Adherence Scale (ProMAS) questionnaire, PDI data and fasting blood glucose (FBS) examination results in medical records using data collection documents. Correlation analysis between PDI and medication adherence and glycemic control used the Kendall's tau-b/c test. Results showed patients were mostly male (53.84%), age ≥65 (43.20%), elementary school education (35.50%), unemployed (63.90%), no family history (70.41%), disease duration 5 years (62.72%), with comorbidities (65.09%), and FBS achieved (81.66%). The antidiabetic used was a combination of metformin and glimepiride (54.43%). A total of 81.65% obtained routine PDI with high medication adherence (48.52%). The conclusion of the study was that there was a significant relationship between PDI with medication adherence (p=0.000; r=0.253) and glycemic control (p=0.000; r=0.447).
Relationship Between Menstruation and Nutritional Status to Anemia in Female High School Students in Mentawai Islands, 2018 Dewi, Elizabeth Ameilia; Setiawan, Christianus Heru; Kurniadi, Angela; Tanumihardja, Tommy Nugroho
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 22, No 2 (2025)
Publisher : Sanata Dharma University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24071/jpsc.008646

Abstract

Anemia is a significant health concern, especially among adolescent females in Indonesia. Menstruation and poor nutrition are major contributors to anemia, since menstruation leads to red blood cell loss and poor nutrition hinders production. This study examines the relationship between menstrual characteristics, nutritional status, and anemia among high school female students in Muara Siberut Village, Mentawai Islands. This cross-sectional observational study involved 97 female high school students. We assessed nutritional status using BMI percentiles and categorized menstrual characteristics according to standard gynecological classifications. Anemia was diagnosed via hemoglobin measurements using a digital hemoglobinometer. Statistical analyses (p0.05) with odds ratio (OR) and 95% confidence interval (CI) utilized Chi-square or Fisher’s exact tests to explore associations between menstrual characteristics, nutritional status, and anemia. No significant correlation was observed between nutritional status and anemia (p=0.394). Conversely, a significant correlation was found between the menstrual cycle and anemia (p=0.023) as well as between menstrual length and anemia (p=0.017). Furthermore, a subgroup analysis revealed individuals with a normal menstrual cycle were at a higher risk of experiencing anemia compared to those with oligomenorrhea (OR=4, 95%CI=0.988–16.199). Additionally, the results indicated that individuals with normal menstrual length were at a higher risk of experiencing anemia compared to those with hypomenorrhea (OR=4.624, 95%CI=1.174–18.202). This study provides valuable insights into the predictors of anemia among female adolescents, emphasizing the need for targeted health education and interventions.
Relationship Between Perceptions Of Flu Advertisement With Self-Medication Behavior In The Community Of Sungai Besar Sub-District, Banjarbaru Selatan Chandra, M. Andi
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 22, No 2 (2025)
Publisher : Sanata Dharma University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24071/jpsc.006075

Abstract

Flu is one of the diseases that can be treated with self-medications, and information about these drugs is often obtained through advertisements on television, which will influence self-medication behavior. The purpose of this study was to analyze the relationship between perceptions of cold medicine advertisements and self-medication behavior using cold medicines. The method used in this study was an analytic survey with a cross-sectional research design and the sampling technique used was quota sampling. The sample of this study was 94 respondents with the majority of sample aged 17-27 years, female, high school/vocational high school graduates, who work as housewives. The results showed that respondents' perceptions of drug advertisements in self-medications were 10.64 % of respondents were affected and 89. 36 % of respondents were not affected. The self-medication behavior done by the respondents was 65.96% rational and 34.04% irrational. The results of the chi-square analysis showed that there was no significant relationship between perceptions of cold medicine advertisements and self-medication behavior using cold medicines (p value = 0.225). The results of the evaluation and the completeness of advertisements for cold medicine on television showed that some advertisements for cold medicines broadcast on television were still incomplete and inappropriate. The importance of rational use of medications should be a guide in all self-medication for the safety and maintenance of public health.
Spray Gel Formulation of Goroho Banana (Musa acuminata L.) Peel Extract: Optimization and Wound Healing Activity Analysis Salainti, Madeleine Trisha; Yuliani, Sri Hartati
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 22, No 2 (2025)
Publisher : Sanata Dharma University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24071/jpsc.0011512

Abstract

Goroho banana (Musa acuminata L.) peel extract has been traditionally used in Minahasa for wound healing. This study aimed to develop and optimize a spray gel formulation containing Goroho banana peel extract and evaluate its wound healing activity. A factorial design was employed with two factors (Carbopol 940 and HPMC) at two levels. Preliminary testing determined 3% as the optimal extract concentration through wound healing evaluation in rats. Four spray gel formulations were developed and characterized for physicochemical properties, including viscosity, pH, and drying time. Results showed Formula B (Carbopol 0.5% and HPMC 0.6%) exhibited optimal characteristics with viscosity 223.8 ± 7.6 cPs, pH 5.13 ± 0.05, and drying time 4.22 ± 0.05 minutes. The HET-CAM irritation test revealed mild irritation scores (2.5-3.8) for all formulations, with Formula B showing the lowest score (2.5). Design Expert optimization generated 100 solutions, with the optimal formula containing Carbopol 0.670% and HPMC 0.517%. The wound healing activity showed no significant differences between spray gel formulations and Bioplacenton (p0.05), indicating comparable efficacy. This study demonstrates the successful development of a safe and effective spray gel formulation of Goroho banana peel extract for wound healing applications.

Page 25 of 25 | Total Record : 247

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