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Universa Medicina
Published by Universitas Trisakti
ISSN : 19073062     EISSN : 24072230     DOI : -
Core Subject : Health, Science,
Health Professions Immunology & microbiology Medicine & Pharmacology Public Health
Universa Medicina (univ.med) is a four-monthly medical journal that publishes new research findings on a wide variety of topics of importance to biomedical science and clinical practice. Universa Medicina Online contains both the current issue and an online archive that can be accessed through browsing, advanced searching, or collections by disease or topic
Arjuna Subject : -
Articles 602 Documents
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Microbiological profile of diabetic foot infections and the detection of mecA gene in predominant Staphylococcus aureus Ponmurugan Karuppiah; Suresh S. S. Raja; Muhammad Musthafa Poyil
Universa Medicina Vol. 41 No. 2 (2022)
Publisher : Faculty of Medicine, Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2022.v41.121-128

Abstract

BACKGROUNDDiabetes mellitus (DM) is a serious health problem that is rapidly expanding worldwide. Staphylococcus aureus is a pathogenic bacterium which has a number of drug resistant strains. Different variants of this pathogen have been isolated from patients with diabetic foot ulcers - in persons having uncontrolled blood sugar level - all over the world, resulting in high rates of morbidity and mortality. The objective of this study was to determine the prevalence of drug resistant Staphylococcus aureus in diabetic foot infections (DFIs). METHODS An epidemiological survey was conducted and 300 pus samples were collected from wounds, abscesses, skin and soft tissue lesions of patients having type II diabetes with foot ulcer infections at a tertiary care hospital. Further, the antibacterial susceptibility patterns of all the isolated Staphylococcus aureus were determined against methicillin, oxacillin, vancomycin and novobiocin. RESULTS Pathogenic bacterial species including coagulase positive and coagulase negative Staphylococcus aureus, Escherichia coli, Klebsiella sp., Proteus sp., Pseudomonas sp., and Citrobacter sp. were identified, among which Staphylococcus was the main genus identified. A total of 13 (4.3%) isolates of coagulase positive Staphylococcus aureus were resistant to methicillin. Using PCR, 7 (53.8%) staphylococcal isolates were detected with the mecA gene. CONCLUSIONStaphylococcus aureus is the most common cause of DFIs. This study demonstrates that about 53.8% of all methicillin resistant Staphylococcus aureus isolates have mecA genes. Such a finding is the primary step in understanding and tackling the resistance mechanism.
Reflections on the concept of sedentary behavior during the COVID-19 pandemic Leandro Dragueta Delfino
Universa Medicina Vol. 41 No. 2 (2022)
Publisher : Faculty of Medicine, Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2022.v41.101-103

Abstract

Highest economic status increases risk of cesarean section in women of childbearing age Idris, Haerawati; Anggraini, Rini
Universa Medicina Vol. 41 No. 2 (2022)
Publisher : Faculty of Medicine, Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2022.v41.129-138

Abstract

BACKGROUNDCesarean section (CS) rates that are higher than the WHO recommendation may pose morbidity and mortality risks for both mother and child. In recent years, the number of CS deliveries has been increasing in developed and developing countries. The aim of the present study was to determine the rate of CS delivery and socioeconomic and demographic factors as risk factors of cesarean delivery in women of childbearing age. METHODSThis cross-sectional study used data from the 2017 Indonesian Health Demographic Survey (IDHS). The research subjects were 14,724 women of childbearing age aged 15-49 years who had given birth and met the inclusion criteria. The rate of CS was determined and the associations between independent and dependent variables were explored using logistic regression. RESULTSThe CS rate was 17.9%. Variables that had a significant relationship with cesarean delivery were geographic region, economic status, occupation, education, birth attendant, insurance ownership and antenatal care visits. The most dominant influencing variable was the highest economic status (OR 3.566; 95% CI: 2.857-4.452). Respondents with the highest economic status had a 3.5 times greater risk of having a cesarean delivery than subjects with the lowest economic status after controlling for the other variables. CONCLUSIONThis study demonstrated that the highest economic status increased the risk of CS delivery in women of childbearing age. The current epidemiological findings and evidence suggest adopting and implementing some strict guidelines in the health system to avoid unnecessary delivery by CS.
Diabetes mellitus patients in Indonesia: management in a tertiary hospital compared to primary health care Hikmat Permana; Raspati Cundarani Koesoemadinata; Nanny Natalia Mulyani Soetedjo; Nury Fitria Dewi; Novi Jayanti; Sofia Imaculata; Rovina Ruslami; Bachti Alisjahbana; Susan Margaret McAllister
Universa Medicina Vol. 41 No. 2 (2022)
Publisher : Faculty of Medicine, Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2022.v41.157-168

Abstract

Background The increasing prevalence of diabetes mellitus (DM) requires that patients have greater access to care, which is yet lacking in many low- and middle-income countries and the quality of which varies between health care facilities. We compare the characteristics, complications, and risk profile of diabetes in patients receiving care in primary and tertiary level health facilities in Bandung, Indonesia. MethodsAdult DM patients were recruited from 25 community health centres (CHCs) and the outpatient clinic at one referral hospital. Key data collected and compared to national guidelines were DM history, treatment, complications, blood pressure, height, weight, and laboratory examinations on glycated haemoglobin (HbA1c), lipid profile, and creatinine. Data analysis was by chi-square test. ResultsOf the 809 DM patients (median age 59 years, 63% female, 98% type 2 DM), 318 (39%) were from CHCs and 491 (61%) from the hospital. Overall median HbA1c was 8.3%, with no difference between CHC and hospital patients. Only 32% of patients with HbA1c ≥10% were on insulin (CHCs 5.9%, hospital 42.9%), and only 18% of those on insulin had glycaemic control. Hypertension was common (CHCs 62%, hospital 51%, p<0.001), and only 44% of CHC and 34% of hospital patients received antihypertensive therapy. Among those with macrovascular complications, only 32% (CHCs) and 26% (hospital) were receiving aspirin. The numbers reaching the treatment targets were low for those on antihypertensives and lipid-lowering medications (80/251 and 11/105, respectively). ConclusionGlycaemic control and management of complications of DM patients at both health care levels need considerable improvement.
Anger control is the most influential risk factor of mobile phone addiction among nursing and midwifery students of Zahedan University of Medical Sciences Sadegh Dehghanmehr; Fatemeh KordSalarzehi; Najmeh Ghiamikeshtgar; Nahid Mir; Mahsima Banaei Heravan; Farhad Shafeie
Universa Medicina Vol. 41 No. 2 (2022)
Publisher : Faculty of Medicine, Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2022.v41.149-156

Abstract

BackgroundReligious attitude and anger management are two psychopathological constructs receiving little empirical scrutiny in relation to smart phone addiction, but theoretically should demonstrate significant relationships. Today one of these new media that is used by many people around the world, is the mobile phone. Students are one of the most important groups that are affected by mobile social networks. The aim of this study was to determine religious attitudes and anger management as risk factors of mobile phone addiction in nursing and midwifery students. MethodsThis study was a cross-sectional study involving 200 nursing and midwifery students. Relevant data were collected through demographic information questionnaire, anger management skills questionnaire, religious attitude questionnaire, and mobile phone addiction questionnaire. A multiple regression model was used to examine the relationship between variables. ResultsThe mean age of the research subjects was 22.04 ± 3.30 years. Anger control and religious attitude were a significant risk factors of smartphone addiction (β=-0.500; p=0.000; β= -0.069; p=0.004, respectively). The variables of anger ýcontrol and spiritual attitude can predict and explain 33.6% and 2.7% (36.3% in total) of the ýchanges in the mobile addiction score. Anger control is the most influential risk factor of mobile phone addiction among nursing and midwifery students (Beta = -0.385). ConclusionFindings indicate the importance of controlling anger and strengthening religious attitude in reducing the rate of mobile phone addiction in students. This provides guidance to the future development of smartphone addiction prevention programs for students.
Psychological distress and dyslipidemia in adult women: A 6-years follow up study in Bogor City, Indonesia Sulistyowati Tuminah Darjoko; Sudarto Ronoatmodjo; Srilaning Driyah; Dewi Kristanti; Dwi Hapsari Tjandrarini
Universa Medicina Vol. 41 No. 3 (2022)
Publisher : Faculty of Medicine, Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2022.v41.236-245

Abstract

BACKGROUNDDyslipidemia is of global occurrence, with a prevalence 30% or higher in several countries, including Indonesia. One risk factor of dyslipidemia is physical or mental stress, that is more frequent in women. This study aimed at investigating the association between psychological distress and dyslipidemia in adult women. METHODSThis observational longitudinal study involved 1850 women aged 25 years and older at baseline. Dyslipidemia was determined from the ratio of low- density lipoprotein to high-density lipoprotein. Psychological distress was determined using the 20-item self-reporting questionnaire. Data analysis was by Cox regression for calculating the hazard ratio of the incidence of dyslipidemia as predicted by the psychological distress. RESULTSAmong the 1474 participants without dyslipidemia at baseline, 545 (36.9%) developed dyslipidemia during 6 years of monitoring, while 93 (6.3%) had a history of psychological distress. There was a significant association between psychological distress and dyslipidemia (HR = 3.08; 95% CI: 2.33- 4.07). Cox regression revealed that the association was still found to be significant after a further adjustment for the variables of age, BMI, menopause, smoking status, physical activity, and carbohydrate and fat intakes (HR=2.8; 95% CI: 2.10 - 3.77). CONCLUSIONSDyslipidemia incidence was high among adult women in Bogor. Women with psychological distress had higher incidence rates of dyslipidemia than women without psychological distress. Psychological distress in women was statistically significantly associated with incidence rate of dyslipidemia. This finding highlights the importance of the need for a dyslipidemia- reduction program in women through prevention and control of psychological distress.
Genetics of circadian rhythm in disease and aging process Juhi Aggarwal; Niharika Singh; Jyoti Batra
Universa Medicina Vol. 41 No. 3 (2022)
Publisher : Faculty of Medicine, Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2022.v41.207-209

Abstract

Association of Chlamydia trachomatis and Neisseria gonorrhoeae with female infertility: a systematic review and meta-analysis Araz Majnooni; Saeed Amel Jamedar; Amir Azimian; Kiarash Ghazvini
Universa Medicina Vol. 41 No. 3 (2022)
Publisher : Faculty of Medicine, Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2022.v41.302-314

Abstract

BackgroundChlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) are commonly diagnosed sexually transmitted infections that have been associated with serious reproductive health outcomes for women. The association of CT and NG infection with female fertility is not completely established yet. This review aimed to determine the association of CT and NG with female infertility. MethodsThis systematic review and meta-analysis was conducted according to the PRISMA statement. We searched a range of electronic databases, including PubMed, Web of Science, Embase, and Scopus, from Sept 25, 2017 until February 1, 2021. From the 851 studies screened, 552 that failed to meet our eligibility criteria were excluded. Subsequently, we removed 290 studies for not having a possible correlation of CT and NG infections with female infertility. Nine studies comprising 1827 infertile patients met our inclusion criteria. Two investigators independently extracted a range of data. All analyses were performed using STATA (version 13.1, Stata Corp, College Station, TX, USA). ResultsCT infection potentiates female infertility, as 76.47% of the included studies found a positive correlation between them. However, due to the limited number of reported data, we were not able to compare NG infection prevalence in fertile and non-fertile patients. Overall prevalences of CT and NG infections among infertile patients were 12 % and 3%, respectively, while CT infection prevalence among the fertile group was 7%. Conclusion The prevalences of CT and NG infections were high in infertile women. Screening and treatment of C. trachomatis and gonococcal infections during infertility treatment might increase the pregnancy rate.
Radiographic lumbosacral angle has a low yield for diagnosing low back pain in workers 20-70 years of age Partogi Napitupulu; Gupita Nareswari; Mulia Rahmansyah; Tandy Chintya Tanaji
Universa Medicina Vol. 41 No. 3 (2022)
Publisher : Faculty of Medicine, Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2022.v41.263-270

Abstract

BACKGROUNDThe increasing trend of working from home (WFH) among workers may lead to prolonged sitting time, which is associated with increased complaints of low back pain (LBP). The lumbosacral angle (LSA) is one of the clinically important radiographic angles related to the curves commonly measured to evaluate the biomechanical factors linked with LBP. The purpose of this study was to determine the yield of radiographic LSA for diagnosing LBP among workers aged 20-70 years. METHODS An analytic cross-sectional study involving 119 participants was carried out in Trisakti University. Lumbosacral angle was measured using Ferguson’s method. Data regarding LBP symptoms, sitting duration, and sitting position were collected using a questionnaire. Sensitivity and specificity was used to describe the characteristics of LSA as a screening test of LBP. RESULTSThe subjects consisted of 66 women (55.5%) and 53 men (44.5 %). Their ages ranged from 20 to 64 years with a median age of 40.0 years. Mean LSA was 37.4 ± 7.3º, while the prevalence of LBP was 75 (63.0%). The optimal cut-off value of LSA for the prediction of LBP was 49.5% (95% CI: 0.385-0.606). The sensitivity, specificity, positive predictive value and negative predictive value of LSA in detecting LBP were 58.7%, 45.5%, 68.8%, and 43.6%. CONCLUSIONSThe radiographic lumbosacral angle has a low yield for the diagnosis of LBP among workers aged 20-70 years. Further studies are needed to confirm our results and to test the application of this measurement.
Anal human papillomavirus genotype distribution and its associations with abnormal anal cytology among men who have sex with men I Ketut Agus Somia; Tuti Parwati Merati; Dewi Dian Sukmawati; Ni Wayan Winarti; IGAA Elis Indira; Ida Bagus Dwija Putra; Made Yogi Oktavian Prasetia
Universa Medicina Vol. 41 No. 3 (2022)
Publisher : Faculty of Medicine, Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2022.v41.246-253

Abstract

BACKGROUND Anal human papillomavirus (HPV) is associated with the severity of anal cytologic abnormalities that are precancerous lesions. Knowledge of HPV type distribution in populations at risk for anal cancer is needed. This study investigated anal HPV infections and cytological abnormalities among men who have sex with men (MSM). METHODS A cross-sectional study was conducted involving 90 men aged >30 years with a history of anal sexual intercourse with men. Demographic characteristics and sexual behaviors were collected by using a self-completed questionnaire. Anal cytological results were examined, and HPV genotyping was performed by the Linear Array HPV genotyping test. Descriptive analyses of subject characteristics, prevalence, and 95% confidence intervals (CI) were performed. A chi-square test was used to determine their associations with high-risk HPV infection and cytological abnormalities. RESULTS The overall prevalence of abnormal cytology was 32% (24/75), atypical squamous cells of undetermined significance (ASCUS) 17.33 % (13/75), 14.66% (11/75) were classified as low-grade SIL (LSIL) and no participant had high-grade SIL (HSIL). Prevalence of HPV infection with normal cytology was 86.27% (44/51), ASCUS 92.30% (12/13), and LSIL 100% (11/11). The most common types of anal HPV in participants with cytological abnormalities are HPV 16, HPV 18 for high-risk HPV, and HPV 11, HPV 6 for low-risk HPV. There were no associations between the predictor variables and the abnormal cytology (p>0.05). CONCLUSION There was a high prevalence of HPV infection in MSM with abnormal anal cytology. A routine anal Pap smear program and vaccination are needed to prevent HPV infection and anal dysplasia in MSM.

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