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Paediatrica Indonesiana

paediatrica-indonesiana
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Published by Ikatan Dokter Anak Indonesia

ISSN : 00309311 EISSN : 2338476X DOI : -

Core Subject : Health,

Health Professions Medicine & Pharmacology

Paediatrica Indonesiana is a medical journal devoted to the health, in a broad sense, affecting fetuses, infants, children, and adolescents, belonged to the Indonesian Pediatric Society. Its publications are directed to pediatricians and other medical practitioners or researchers at all levels of health practice throughout the world.

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Articles 8 Documents

Search results for , issue "Vol 44 No 5 (2004): September 2004" : 8 Documents clear

The prevalence and clinical features of depressive syndrome in children with epilepsy in Cipto Mangunkusumo Hospital, Jakarta Rini Sunarwati; Dwi Putro Widodo; Bambang Madiyono; Willy Edith HP
Paediatrica Indonesiana Vol 44 No 5 (2004): September 2004
Publisher : Indonesian Pediatric Society

Background Symptoms of depression often emerge in childrenwith epilepsy, but parents or caregivers are not always able torecognize them.Objective To assess the prevalence and clinical features of de-pressive syndrome among pediatric epilepsy patients in CiptoMangunkusumo Hospital, Jakarta.Methods This was a cross-sectional study on children aged 8-18 years. Child Depression Inventory (CDI) was used as theinstrument for assessing depressive symptoms.Results Depressive syndrome was found in 34 out of 89 subjects.The three most frequent depression symptoms were self-deprecation (via peer comparison), indecisiveness, and pessimism.Frequency of seizures, mode of therapy, and EEG result wereimportant factors in the development of depressive syndrome inchildren with epilepsy.Conclusions The prevalence of depressive syndrome in childrenwith epilepsy was 38%. Symptoms of depression mostly found inthis study were self-deprecation (via peer comparison), indecisive-ness, and pessimism

Factors associated with shock in children with dengue hemorrhagic fever Erick F Kan; T H Rampengan
Paediatrica Indonesiana Vol 44 No 5 (2004): September 2004
Publisher : Indonesian Pediatric Society

Background Shock in dengue hemorrhagic fever (DHF) still con-stitutes an important problem in children. Predicting DHF patientswho will develop shock is difficult.Objective The aim of this study was to find out factors associatedwith shock in DHF.Methods This was a prospective observational study. Subjectswere children hospitalized from April to July 2000 who met theWHO criteria for DHF and had positive serological confirmation.Association between independent variables (age, gender, dura-tion of fever, abdominal pain, vomiting, hepatomegaly, plateletcount, hematocrit level, and nutritional status) and the dependentvariable (shock) was analyzed by logistic regression model..Results There were 85 children who met the eligibility criteriaconsisting of 50 (59%) boys and 35 (41%) girls with an averageage of 7.1 years (SD 2.88). Shock occurred in 42 (49%) children.Of the 42 children with shock, the age group of 5-9 years madeup the biggest group (57%) consisting of 23 (55%) boys and 19(45%) girls. Hepatomegaly was found in 32 (76%) children, ab-dominal pain and vomiting in 30 (71%) and 36 (86%) children,respectively, and good nutrition in 22 (52%) children. Shock oc-curred mainly on the fourth and fifth days (76%). Almost half ofthe patients (45% and 52%) had hematocrit level of 46-50% andplatelet count of 20,000-50,000/ml, respectively. By logistic re-gression analysis, it was found that duration of fever, abdominalpain, hematocrit level, and platelet count constituted indepen-dent factors correlating with shock in DHF.Conclusion Abdominal pain, fever lasting four to five days, hema-tocrit level of >46%, and platelet count of <50,000/Î¼l were associ-ated with shock in DHF

Hepatitis B serologic patterns in children of HBV carriers or infected mothers Julfina Bisanto; Imral Chair; Dyah Istikowati
Paediatrica Indonesiana Vol 44 No 5 (2004): September 2004
Publisher : Indonesian Pediatric Society

Background Vertical transmission is usually the cause of increas-ing carrier rates for hepatitis B infection, especially in highly en-demic areas.Objective To determine the serologic patterns of hepatitis B inchildren of HBV carrier/infected mothers.Methods This was a cross sectional study on children of HBVcarrier/infected mothers. Subjects were recruited consecutively andexamined at the Department of Child Health, Cipto MangunkusumoHospital during Januaryâ€“July 2003. Children were included if theywere generally healthy and their parents gave permission. Chil-dren with chronic illness, previous blood transfusions, or drug abusewere excluded.Results Fifty-nine children of 32 HBV carrier/infected mothers wererecruited. HBsAg was positive in 8 children, anti-HBs in 37, andanti-HBc in 4 children. Seventy-three percent of children had beenvaccinated against HBV but only 81% had positive anti-HBs. Ofeighteen children who received hepatitis B vaccine and HBIg atbirth, none was infected. Six out of 25 children who received onlyhepatitis B vaccine were infected.Conclusion HBsAg, anti-HBs, and anti-HBc were positive in 14%,36%, and 7% of children of HBV carrier/infected mothers, respec-tively

Prevalence and associated factors of airway hyper- responsiveness in children with recurrent chronic cough I Gusti Agung Ngurah Sugitha Adnyana; Putu Suwendra; Hendra Santoso
Paediatrica Indonesiana Vol 44 No 5 (2004): September 2004
Publisher : Indonesian Pediatric Society

Background Airway hyper-responsiveness (AH) is a common char-acteristic of asthma. Patient who has recurrent chronic cough withAH is commonly referred as â€œcough variant asthmaâ€. Histamineprovocation test should be performed to determine whether a pa-tient has â€œcough variant asthmaâ€ or recurrent viral bronchitis.Objective To determine AH prevalence in children with recurrentchronic cough and factors associated with it.Methods A cross sectional study was conducted on 6-12 year-oldchildren with recurrent chronic cough at the Pediatrics OutpatientClinic, Sanglah Hospital Denpasar from September 2002 until June2003Results Twenty one out of 64 (33%) subjects suffering from recur-rent chronic cough without wheezing had AH. Associated factorssignificantly associated with AH were age, allergic rhinitis, pater-nal and maternal history of atopy, passive smoking, use of mos-quito-coil, positive skin prick test, and eosinophilia. Spearman cor-relation analysis between associated factors and AH showed thatpositive skin prick test and passive smoking were moderately cor-related with AH (r=0.56, p<0.0001; r=0.57, p<0.0001, respectively),whereas multivariate regression logistic analysis on associatedfactors found true associated factors, such as positive skin pricktest (p=0.01; OR=14.82), history of atopy in father (p=0.02;OR=22.75), and passive smoking (p=0.03; OR=11.97).Conclusions The prevalence of airway hyper-responsiveness inchildren with recurrent chronic cough without history of wheezingwas 33%. Independent associated factors of AH in recurrent chroniccough children are positive skin prick test, history of atopy in fa-ther, and passive smoking

Factors associated with oral Candida colonization in neonates at intensive care unit I Putu Wijana; Hendra Santoso; I Made Swastika
Paediatrica Indonesiana Vol 44 No 5 (2004): September 2004
Publisher : Indonesian Pediatric Society

Background Oral candidiasis still has high prevalence andfrequently causes problems in the neonatal period.Objective To evaluate some factors associated with the occurrenceof oral Candida colonization in neonates.Methods A cross sectional study was performed at the IntensiveCare Unit, Neonatology Division, Department of Child Health,Medical School, Udayana University/Sanglah Hospital Denpasar,from November 2002 to April 2003. Eighty neonates were enrolled.Oral mucous swabs were obtained and examined for Candidacolonization using potassium hydroxide (KOH). Data were analyzedby prevalence ratio and logistic regression; a p value of <0.05 wasconsidered significant.Results The prevalence of oral Candida colonization was 55%(44/80). The colonization was significantly associated with age of>1 week, male sex, gestational age of <37 weeks, Apgar score of<7, birth weight of <1500 grams, oral mucous pH of <7, systemicantibiotic use, and steroid use by mother. Breastfeeding was aprotective factor. Correlation between variables using Spearmantest revealed correlation coefficient of <0.5. By logistic regres-sion, birth weight of <1500 grams (p=0.04) and systemic antibi-otic use (p=0.01) were significant associated factors of oralCandida colonization, while breastfeeding was a significant pro-tective factor (p=0.03).Conclusion Birth weight of <1500 grams and systemic antibioticuse were significant associated factors of oral Candida colonizationand breastfeeding was a significant protective factor of oral Candidacolonization in neonates

Comparison of absolute neutrophil count between premature and term infants Ahmad Faisal; Guslihan D Tjipta; Bidasari Lubis; Dachrul Aldy
Paediatrica Indonesiana Vol 44 No 5 (2004): September 2004
Publisher : Indonesian Pediatric Society

Background Neutrophils are very important in the body defenseagainst bacterial infection. Absolute neutrophil count (ANC) couldbe used for the recognition of early-onset bacterial sepsis inneonates.Objective The aim of this study was to compare the value of ANCbetween premature and term infants, to assess the prevalence ofearly-onset neutropenia in premature infants and its relationshipwith prematurity, and to find out the correlation between gesta-tional age and ANC.Methods A cross-sectional study was conducted during Februaryto May 2003. Subjects were newborn infants with gestational ageof less than 37 weeks who were born in Adam Malik and PirngadiHospitals, Medan. Newborn infants with severe asphyxia (5-minuteApgar score of less than 4), fever, seizure, and maternalhypertension were excluded. Complete blood count was done bymeans of automatic cell counter (Micros (R) , Germany). Term healthyinfants were used as control subjects.Results ANC differed significantly between both groups (p=0.0001).The prevalence of early-onset neutropenia in premature infantswas 9% (95%CI 0.065;0.21). Prematurity was related with theincidence of neutropenia with a prevalence ratio of 1.1. Therewas a weak positive correlation between gestational age andANC with an r-value of 0.49 (p=0.0001).Conclusions ANC in premature infants differs from that in terminfants. The prevalence of early-onset neutropenia in prematureinfants was 9% (95%CI 0.065;0.21). Prematurity is related with theincidence of early-onset neutropenia in newborn infants. There isa correlation between gestational age and ANC

Gastroesophageal reflux in children with chronic recurrent cough Mardjanis Said; Rianita Syamsu; Taralan Tambunan; Badriul Hegar
Paediatrica Indonesiana Vol 44 No 5 (2004): September 2004
Publisher : Indonesian Pediatric Society

Background Gastroesophageal reflux (GER) is reported to beone of the most common causes of chronic recurrent cough (CRC).In Indonesia, so far there is no published data concerning GER inchildren with CRC.Objectives To determine the prevalence of GER in children withCRC in general, and asthma in particular; and to describe the clini-cal profile associated with GER in these children.Methods This was a cross sectional study on children with CRCwho were investigated for GER using 24-hour esophageal pHmonitoring. GER was graded based on reflux index (RI) stated inpHmetry results i.e., mild (RI=5-10%), moderate (RI>10-20%), andsevere (RI>20%).Results Among 48 children with CRC, GER was detected in 22(46%) of them (mild GER in 14, moderate in 3, and severe in 5children). In 35 children with asthma, which is the most frequentcause of CRC in our hospital, GER was detected in 15. The preva-lence of GER increased parallel with the frequency of cough epi-sodes i.e., 10/27 in children with infrequent episodes of cough, 4/10 in children with frequent episodes of cough, and 8/11 in chil-dren with persistent cough. Clinical profiles associated with GERin these children were persistent/ frequent episodes of CRC andundernutrition.Conclusions The prevalence of GER in children with CRC was46%, and in those with asthma was 15/35. The clinical profilesassociated with GER are persistent/frequent episodes of CRCand undernutrition

Recurrent cerebral abscess in tetralogy of Fallot Wanty Sahli; J M Ch Pelupessy
Paediatrica Indonesiana Vol 44 No 5 (2004): September 2004
Publisher : Indonesian Pediatric Society

Tetralogy of Fallot (TF) classically consistsof the combination of right ventricularoutflow obstruction (pulmonary stenosis),ventricular septal defect (VSD), overridingaorta, and right ventricular hypertrophy. Thedegree of pulmonary stenosis and VSD determine thevariety of clinical manifestations.This type of congenital heart disease accountsfor about 10% of all congenital cardiac deformitiesand is the most common cyanotic lesion after thefirst year of life. Cerebral abscess is a serious com-plication in TF and is usually seen after the age of 2years.

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