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Paediatrica Indonesiana

paediatrica-indonesiana
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Published by Ikatan Dokter Anak Indonesia

ISSN : 00309311 EISSN : 2338476X DOI : -

Core Subject : Health,

Health Professions Medicine & Pharmacology

Paediatrica Indonesiana is a medical journal devoted to the health, in a broad sense, affecting fetuses, infants, children, and adolescents, belonged to the Indonesian Pediatric Society. Its publications are directed to pediatricians and other medical practitioners or researchers at all levels of health practice throughout the world.

Arjuna Subject : -

Articles 2,118 Documents

153 154 155 156 157

Effect of Recombinant Erythropoeitin in Anemia Due to Chronic Renal Failure Husein Alatas; Fahrul W. Arbi; Taralan Tambunan; I.G.N. Wita Wirya
Paediatrica Indonesiana Vol 37 No 5-6 (1997): May - June 1997
Publisher : Indonesian Pediatric Society

Recombinant human erythropoeitin (rHuEPO) was administered to 16 patients hospitalized at the Department of Child Health Faculty of Medicine University of Indonesia Cipto Mangunkusumo Hospital between July 1992 until December 1994, with anemia (Hb < 8 g dl) due to chronic renal failure (creatinine uclearance < 30 ml/min/1.3 mJ). three of them with end stage renal failure (creatinine clearance < 5 ml/min/1.73 nr). The average age was 15.9 years (range 4-16 years) the proportion of sex were the same. An initial dose of 150 lU/kgBW/week rHuEPO was administered subcutaneously. The dose was increased by 75 U/kgBW/week and maintained when the hemoglobin level reached 11 g/dl. Good result was mostly found at the dose of 150-199 IU/kgBW/week. The hemoglobin level rose from 6.79 + 1.19/dl before treatment to 10.4 + 3.9 g/dl after treaunent (p=0.011). Six cases failed to reach Hb 1 lg/dl, one of them with severe hypertension while in the other case had peritonitis. Decrease of the serum ferritin level during treatment indicated that ferrum was utilized for erythropoesis. This study showed that in chronic renal insufficiency we should consider to give r-HuEPO to increase hemoglobin to avoid giving recurrent blood tranfusion; however, the cost may limit its widespread use.

Transient Blindness in A Child with Dengue Shock Syndrome Irwanto Irwanto; Soegeng Soegiyanto; Parwati Setiono Basuki; Wisnujono Soewono; Diany Yogiantoro
Paediatrica Indonesiana Vol 37 No 5-6 (1997): May - June 1997
Publisher : Indonesian Pediatric Society

Dengue hemorrhagic fever (DHF) is characterized by acute fever associated With haemorrhagic diathesis and tendency to develop fatal shock (dengue shock syndrome). Signs and symptoms of DHF are generally secondary to plasma leakage and hemorrhage. Dengue shock syndrome (DSS) is a severe clinical manifestation of DHF usually as a consequence of severe plasma leakage. During tire last 5 years, there have been reports of DHF patients with unusual manifestations, including some patients with central nervous system (CNS) involvement We report a 5 year old DHF patient who experienced transient blindness, which was the first case found in Soetomo Hospital, Surabaya.

AIDS in Indonesia: Current Problems, Future Impacts and Challenges Muzief Munir; Jasrizal Ilyas; Nyoman Suesen; Harmon Mawardi; Widagdo Widagdo
Paediatrica Indonesiana Vol 37 No 9-10 (1997): September - October 1997
Publisher : Indonesian Pediatric Society

Since the First cases of AIDS were reported in the USA in 1981 and in Indonesia in 1987, millions of people throughout the world have been contracting this threateningly fatal disease. This report discusses and highlights the current problems and the future impacts of the disease in Indonesia. Data were collected from the Sub-Directorate STDs Control of the Directorate of Communicable Disease Control, Department of Health. The majority of cases were sexually active men and women between the ages of 15-49 years with the peak between 30-39 years in AIDS, and between 20-29 years in HIV(+), The mean age of HIV(+) males and remales was staÂtistically different (p<0.0002), where the mean age of HIV(+) males was 29.5 years, while in females it was 24.7 years. This new fatal disease has been reported from 15 out of 27 provinces in Indonesia, mainly from Jakarta, Bali, Riau, East Java and West Irian. Due to inadequate knowledge, and a limited surveillance of AIDS in Indonesia, no child was reported as having HIV(+)/AIDS.

A Case of HIV (Human Immunodeficiency Virus) Infected Child Born to HIV Positive Mother Corry S. Matondang; Siti D. Wisnuwardhani; Rulina Suradi; Hindra I. Satari; Graham RR; Sjawitri P. Siregar; Arwin A.P. Akib; Zakiudin Munasir
Paediatrica Indonesiana Vol 37 No 9-10 (1997): September - October 1997
Publisher : Indonesian Pediatric Society

A case of HIV infected Indonesian baby girl bom from an HIV positive mother is reported. This is the first HIV infected child reported in Indonesia. The diagnosis was based on the positive DNA HIV and HIV culture in the baby's blood taken at 3 days old. At this time the baby is still asymptomatic. Despite this we gave her prophylactic treatment against Pneumocystis Carinii infection to prevent the possibility of Pneumocystis Carinii Pneumonia which is usually fatal under 1 year old. The positive HIV at 3 days old may indicative of intrauterine nans mission. Because she is still asymptomatic, the intrauterine infection may be occured during late gestation. In spite of this we hope that the HIV- infection in this baby is not a progressive one.

Adolescent Somatic Development of Junior High School Students in Denpasar Soetjiningsih Soetjiningsih
Paediatrica Indonesiana Vol 39 No 5-6 (1999): May - June 1999
Publisher : Indonesian Pediatric Society

Junior high school adolescent represents a transition period from child toadult. In this period the growth and development takes place very rapidly. This study intended to understand adolescent somatic development of junior high school students in Denpasar; subjects were 450 students of grades I, II, III from 3 junior high schools in Denpasar selected randomly in February 1998. Anthropometric and blood pressure measurements were performed. The structured questionnaires were given to the parents, which were collected during the anthropometric measurement.Â The results were that only 428 subjects completed their data, consisted of 200 boys and228 girls. At the age of t2 years the average anthropometricÂ measurements were higher in girls, but at the age of 13, 14, IS years, the boys was higher. The average systolic blood pressure was 101.67 mmHg and diastolic was 75.0 mmHg, no significant difference between boys and girls. Based on NCHS standard, it was found that 10 % of boys and 3.5% of girls had body weight below the normal limits, and 5.5% boys and 7.9% girls having body height below the normal limits. The average age of menarche was 12.47 years (range 11 -14 years, SD 0.81). The somatic development or boys and girls of junior high school students which wasÂ investigated followed the normal development sequence. Only small number of adolescent found having body weight and height below the normal limits.

Transfer of dietary allergen in human milk Aryono Harsono; Anang Endaryanto
Paediatrica Indonesiana Vol 39 No 7-8 (1999): July - August 1999
Publisher : Indonesian Pediatric Society

The presence of dietary allergens in breast milk have been studied eitherin animal model or human milk. Transfer of these allergens to the infants have been proven qualitatively and quantitatively. Maternal dietary allergen transfer can also be detected by the presence of antibody response in the infants. The relationship of maternal dietary allergens and sensitisation to the infants can be observed in prolonged breastfed infants. The benefit of maternal dietary avoidance may be found either early from the beginning of pregnancy or in the lactation period. Factors predicting the onset of atopic disease are the nature of dietary protein in breast milk, lgA in breast milk, family history of atopy, allergen exposure, cord blood IgE and contributory factors. Evaluation of infants with sensitivity to dietary allergen in breast milk mainly is DBPCFC. Preventive measure is still avoidance of maternal dietaryÂ allergen. The mainstay of treatment is avoidance of the offending foods obtained from food challenge.

Renal tubular function of the child with thalassemia major who received repeated blood trransfusion Dany Hilmanto; Boed Sinai Singadipoera; Ponpon Ijradinata
Paediatrica Indonesiana Vol 39 No 7-8 (1999): July - August 1999
Publisher : Indonesian Pediatric Society

A descriptive study was done from December 2 , 1994 to January 5,1995, at the Department of Child Health of Hasan Sadikin General Hospital Bandung. A total of 50 thalassemia major patients who bad received 5,000 ml or more of blood transfusions and never received desfenioxamine underwent a renal tubular function test using a radionuclide technique (l-123 Hippuran) to determine the effective renalplasmft flow (ERPF). The subjects were div:ided into two groups according to the amount of transfusion. Group A who received a total of 5,000 to 10,000 mL of blood transfusion consisted of 23 children (11 boys and 12 girls); group B, those who received a total of 10,000 ml or more of blood transfusion, consisted of 27 children (14 boys and 13 girls). The total average of blood transfused for group A and B were 7563.91 (1780.59) and 20,665.93 (6632.39) rnl, respectively. The ERPF of all subjects were below the normal standard. The average value of ERPF of group A and B were 205.78 (62 .08) and 214.09 (59.44) ml/minute/1.73 m2, respectively. The correlation between the total amount of blood transfusion and ERPF of the subjects was not significant (Group A had r=O.l63, p=0.458; Group B had r=0.084, p=0 .934).

Exposure pattern of house dust mites in childhood asthma along the year: A series of 10 cases Zakiudin Munasir; Lenny S. Budi; Titi Sularyo; Sri Rezeki Hadinegoro
Paediatrica Indonesiana Vol 39 No 7-8 (1999): July - August 1999
Publisher : Indonesian Pediatric Society

House dust mite (HDM) is one of the inhalant allergens causinginflammation of respiratory tract. More than 100 dust mites/ gram house dust may cause sensitization in childhood asthma, while more than >500 house dust mite/gram house dust may cause asthma attack. This report aimed to determine the exposure pattern of house dust mites on 10 asthmatic children during one year. Homevisit to all patients was done every month to obtain house dust sample, measurement of relative humidity, bed room temperature, and to evaluate the clinical scores and peak expiratory flow rate (PEFR). The range value of house dust mite/gram house dust was 0-340. This study shows that house dust mite may cause of acute asthma attack when accompanied by nonspesific stimuli. In September the relative humidity is high, the temperature is low, and the amount of house dust mite/gram of house dust is highest, in contrast to in August and December. This study shows no seasonalvariation. The amount of house dust mite/ gram of house dust was found higher at the mattress than in the floor of bed room. The species of house dust mite that predominantly found is Dermato- phagoides pteronyssinus. We conclude that house dust mite may cause acute asthma attack whenever accompanied by nonspesific stimulus.

Pattern of infectious diseases in acute leukemia during induction therapy Sri Rezeki Harun; Debbie Latupeirissa; Taralan Tambunan
Paediatrica Indonesiana Vol 39 No 7-8 (1999): July - August 1999
Publisher : Indonesian Pediatric Society

An prospective study was conducted to determine risk factors and pattem of infectious diseases in acute leukemia during induction therapy. The study subjects were all new acute leukemia patients of J month to 17 years old diagnosed between August 1, 1997 and July 31, 1998 in theÂ Department of Child Heallb, Cipto Mangunkusumo Hospital, Jakarta. Subjects were categorized into Group with and without infection. Of the 39 subjects studied (23 boys and 16 girls), 22 subjects were infected (10 boys and 12 girl ). Most of the subjects were 1-4 year-old age group and 14 subjects of that group were infected. lt was found that there wereÂ relationships between incidence of infection with leukocyte count below 5000/ÂµL (p=0.02), neutrophil count below 1x109/L (p=0.01), and evidence of presumptive site of infection (p=0.0005). Children under 5 years old, sex, ANLL type, malnutrition, or neutropenia of more than 2 weeks had no relationships with incidence of infection. Besides fever, pattem of infection diseases in acute leukemia patients during induction therapy, were only 36% and 38% of subjects had clinical manifestations evidence andmicrobiologically documented, respectively. Most of the laboratory findings were leukopenia or neutropenia, while serum aminotransferase was normal in both groups. Serum CRP serum was devated in those with infection. All of the isolated bacteriae were Gram-negative; 52.4% of infected subjects had responded to empirical therapy, and 72.7% of the antibiotics used was sefotaxime.

Tuberculine test in infants and children who have contact to sputum positive adult pulmonary tuberculosis patients Khainir Akbar; Ridwan M. Daulay; Helmi Lubis; Zakaria Siregar; Gabriel Panggabean; Nuraida Nuraida
Paediatrica Indonesiana Vol 39 No 7-8 (1999): July - August 1999
Publisher : Indonesian Pediatric Society

This study aimed to determine the pattern of pulmonary tuberculosisinfection in infants and children who had household contact to adtult tuberculosis patients with sputum positive for acid-fast bacilli (AFB). Tuberculine (Mantoux) test was performed in 270 such infants or children. The results showed that tuberculine test positivity in household contact group of adult tuberculosis patients with positive AFB sputum were significantly different from patients with negative AFB sputum for the age groups 0-18, 0-14, 0-4, 5-9, 10-14 years but not for 15-18 age group. There were no significant difference in positivity of tuberculine test result according to gender or BCG vaccination status, but there was significant difference between children who slept in the same bed room with the source case and those who did not. Semi-quantitative bacteriological status of the sputum (AFB +, or++ or+++) did not affect positivity of tuberculine test result. We conclude that infants and children with household contact to sputum positive adult pulmonary tubercula is patients are at high risk for developing tuberculosis infection particularly those who sleep in the samebed room with the source case.

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