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Paediatrica Indonesiana
Published by Ikatan Dokter Anak Indonesia
ISSN : 00309311     EISSN : 2338476X     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology
Paediatrica Indonesiana is a medical journal devoted to the health, in a broad sense, affecting fetuses, infants, children, and adolescents, belonged to the Indonesian Pediatric Society. Its publications are directed to pediatricians and other medical practitioners or researchers at all levels of health practice throughout the world.
Arjuna Subject : -
Articles 2,127 Documents
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Correlation between immunization status and pediatric diphtheria patients outcomes in the Sampang District, 2011-2015 Kevin Sastra Dhinata; Atika Atika; Dominicus Husada; Dwiyanti Puspitasari
Paediatrica Indonesiana Vol 58 No 3 (2018): May 2018
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (335.279 KB) | DOI: 10.14238/pi58.3.2018.110-15

Abstract

Background The number of diphtheria cases recently increased, such that an outbreak was declared in East Java Province, which includes the Sampang District. Immunization completion status is a determining factor for diptheria infection. Objective To investigate for correlations between immunization status and outcomes (severity level, fatality, and complications) of diphtheria patients in the Sampang District. Methods This analytic, cross-sectional study used secondary data from the East Java Provincial Health Office on diphteria patients aged 0-20 years during the 2011-2015 outbreak in the Sampang District and interviews with diphtheria patients in that region. The Diphtheria Research Team of Soetomo Hospital collected data on immunization status, diphtheria severity (mild, moderate, or severe), case fatality (died or survived), and complications in the patients (with or without complications). Spearman’s, Chi-square, and Fisher’s exact tests were used for data analyses, accordingly. Results Seventy-one patients with clinical diphtheria were identified, 17 of whom were confirmed with positive culture results. The case fatality rates were 7% in patients with clinical and 5.9% in confirmed diphtheria. There were no correlations between patient immunization status and severity (P=0.469 clinical, P=0.610 confirmed), or fatality (P=0.618 clinical, P=0.294 confirmed) of diphtheria in the clinical and confirmed diphtheria patients. However, there was a correlation between patient immunization status and the emergence of complications in clinical (P=0.013), but not in confirmed (P=0.620) diphtheria patients. Conclusion There is a correlation between immunization status and complications in clinical diphtheria patients. Such a correlation is not found in confirmed diphtheria cases because none of the patients had complete immunization status.
Side effects of long-term antiepileptic drugs on renal tubules of Indonesian children Partini Pudjiastuti Trihono; Deasy Grafianti; Irawan Mangunatmadja; Mulya Rahma Karyanti
Paediatrica Indonesiana Vol 58 No 2 (2018): March 2018
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (227.755 KB) | DOI: 10.14238/pi58.2.2018.84-9

Abstract

Background Long-term treatment with antiepileptic drugs such as valproic acid (VPA) and carbamazepine (CBZ) may disrupt renal tubular function. Urinary N-acetyl-beta-D-glucosaminidase (NAG) may reflect tubular function and may be useful in detecting early-stage tubular injury. To date, no study has investigated the toxic effect of VPA and CBZ on renal tubules using urinary NAG in Indonesian children. Objectives To determine the toxicity of long-term VPA and/or CBZ treatment on renal tubules in children with epilepsy by measuring urinary NAG index (iNAG). Methods This cross-sectional study was conducted from January to March 2015 at Cipto Mangunkusumo Hospital and Anakku Clinic Pondok Pinang, Jakarta. We included children aged 3 to 16 years with epilepsy on VPA (n=36), CBZ (n=14), or VPA-CBZ combination (n=14) therapy. We measured urinary levels of creatinine and NAG. The urinary NAG reference value was obtained from age-matched healthy controls (n=30). To eliminate diurnal variations in NAG, iNAG was calculated by dividing urinary NAG by urinary creatinine. A urinary iNAG of more than two standard deviations above the mean for healthy children was considered elevated. Results Mean urinary iNAG values for the control, VPA, CBZ, and combination groups were 3.01, 5.9, 4.07, and 6.9 U/g, respectively. All treated groups had higher mean urinary iNAG values compared to the control group. Urinary iNAG was increased in 11/36 children on VPA, 2/14 children on CBZ, and 9/14 children on combination therapy. Conclusion Long-term VPA use may impair renal tubular function, as shown by the increased urinary iNAG. Combination therapy increases damage in the renal tubules.
The Role of PKK in the Immunization Progmmme Soegen Soegijanto; Dwi Atmadji S.; Parwati Setiono B.; Ismoedijanto Ismoedijanto; Widodo D. M.; Aried Kaspan
Paediatrica Indonesiana Vol 29 No 7-8 (1989): July - August 1989
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi29.7-8.1989.133-40

Abstract

A mid term evaluation of the immunization programme had been carried out in East Java from November 27, 1987 to December 6, 1987. The team consisted of various multidisciplines comprising members of the WHO (3), the Department of Health (4), the Medical Faculty (1), the PKK group (1), and Bangdes. Data showed that the Posyandu, the Health Centres, Hospitals and private doctors contributed to the programme by 69%, 28%, 2% and 1% respectively. It was obvious that although not satisfactory, the Posyandu was by for the mostly committed, reflecting the role of the PKK group especially in terms of encouraging mothers to bring their children to the Posyandu. As one face facts of low educated mothers, mothers being trapped in their routine daily activities, or having had inconvenient medical experience, a low motivation towards immunization might be anticipated, which in turn leads to a low coverage of immunization. Taking into consideration of how the PKK group plays its role in the immunization programme, attempts made to improve knowledge on immunizable diseases and their measures for prevention would undoubtly be an important means of support to gain the aim of immunization.
The Association Between Neonatal Polycythemia, Hypocalcemia, and Hypoglycemia Abdurachman Sukadi; S. Fatimah Endropranoto; Wibisono Suwarno; Hadiawati Sastranegara
Paediatrica Indonesiana Vol 29 No 7-8 (1989): July - August 1989
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi29.7-8.1989.141-5

Abstract

A study about the association between neonatal polycythemia, hypoglycemia, and hypocalcemia was carried out at the Hasan Sadikin General Hospital Bandung, Indonesia, between November 1986 and August 1987. Fourty-six neonates with polycythemia were enrolled in the study and 92 neonates born during the same period formed the control subjects. The control subject neonates were sampled among those with equal birth weight and gestational age compared to the polycythemia subjects. Blood glucose levels were examined more than three hours after birth and before the first feeding by using the God-PAP method and blood calcium levels at less than 24 hours of age by using calorimetric method. The cut-off point for hypoglycemia and hypocalcemia were 30 mg% and 7 mg%, respectively. The results showed that there was a significant difference for hypoglycemia (p < 0,01) and hypocalcemia (p < 0.05) between the exposed subjects and the control subjects
Ultraviolet-related ocular problems in children living on the coast of Southwest Sumba, Indonesia Ratna Sitompul; Rita Sitorus; Julie Barliana; Rossalyn Andrisa; Budiman Prakoso; Hisar Daniel; Gladys Kusumowidagdo; Saleha Sungkar
Paediatrica Indonesiana Vol 58 No 3 (2018): May 2018
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (233.339 KB) | DOI: 10.14238/pi58.3.2018.128-32

Abstract

Background A previous study has shown a high proportion of visual impairment and blindness in the adults of Southwest Sumba, Indonesia due to ultraviolet-radiation (UVR)- related ocular problems, such as cataract and pterygium. Currently, there is no data regarding the effect of ultraviolet (UV) exposure on children and its future implications. Objective To seek the predisposing factors of UVR ocular problems in the children of Southwest Sumba. Methods A population-based cross-sectional study was conducted in Perokonda Village, Southwest Sumba in May 2017. A total of 337 children <16 years old were examined for ocular problems by ophthalmologists. Subjects with ocular problems were then treated accordingly. Results Visual acuity was normal in 98.2% of subjects. Visual impairment and blindness were found in 1.2% and 0.3% of subjects, respectively. Ocular problems were found in 38%, consisting of conjunctival pigment deposits (60.2%), pinguecula (15.6%), and pterygium (13.3%). The UVR ocular problems constituted 33.8% of all ocular problems, comprising conjunctival pigment deposits (22.8%), pinguecula (6%), and pterygium (5%). Conclusion The proportion of UVR ocular problems in the children of Perokonda village is 34.5%, the most common of which being conjunctival pigment deposits. Such deposits may be early signs of UVR ocular problems. This study serves as a platform to highlight the possible relationship between pigment deposits and future UVR ocular problems, which warrants further study.
Neonatal meningitis at Dr. Pirngadi General Hospital Medan (1972 -1980) Rahayu Saat; Sondang Tambunan; Adi Sutjipto; Noersida Raid; Bistok Saing
Paediatrica Indonesiana Vol 24 No 7-8 (1984): July - August 1984
Publisher : Indonesian Pediatric Society

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Abstract

A retrospective study was done on 25 cases of Neonatal Meningitis from 1972 up to 1980 at Dr. Pimgadi Hospital Medan. Their age variation was from one day to one month. The early prominent symptoms were refusal of feeding in 23 cases (92%), decrease of consciousness in 21 cases (84%), fever in 16 cases (64%}, convulsion in 15 cases (60%) and vomiting/diarhea in 8 cases (32%). Diagnosis was based on clinical symptoms and Cerebrospinal fluid examination.
Rotavirus gastroenteritis in Medan (part four) Achmad Razali; Ahmad Jufri; Mansur Karo Karo; A. H. Sutanto; Helena Siregar
Paediatrica Indonesiana Vol 24 No 7-8 (1984): July - August 1984
Publisher : Indonesian Pediatric Society

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Abstract

From April to May 1982, 59 children with gastroenteritis, aged 0 - 3 years (34 males and 25 females) had been examined for Rotavirus at the Department of Child School of Medicine, University of North Sumatera/Dr. Pirngadi General Hospital, Medan. Rotavirus detection was done with the Elisa method. It was found that 32 patients (54.24%) had Rotavirus in their feces. The youngest patient was 2 days old. Vomiting was more pronounced in the Rotavirus group. Degree of temperature did not differ significantly in both groups. From the 32 Rotavirus patients, 71.81% was bottle fed and 28,12% breast fed. From the bottle fed infants with diarrhoea, there were 23 (79,31 %) patients with Rotavirus. From the 21 breast fed patients with diarrhoea, there were only 9 (42,85%) infants with Rotavirus.
Types of allergen affecting asthmatic children M. P. Damanik; A. Samik Wahab; Ediyono Ediyono; Ismangoen Ismangoen
Paediatrica Indonesiana Vol 24 No 7-8 (1984): July - August 1984
Publisher : Indonesian Pediatric Society

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Abstract

An intracutane tuberculin test with several types of allergens was conducted on 110 asthmatic children under the age of 14 years at the Subsection of Allergic diseases and Immunology of the Internal Diseases Section, in cooperation with the Department of Child Health, Gajah Mada University, Pugemn Hospital, in Yogyakarta. The number of children found to be sensitive to house dust, human dander, grass pollen, fungus, collection of animal danders, "mite" (Pteronysinus pterygoideus), and bacteria vaccine were 82 (75,5%), 80 (72. 7%), 0 (0%), 3 (2. 7%), 1 (0,9%), 23 (20.9%), and 20 {18.1%), respectively. It was also found that four ( 3.6%) of the children did not develop any reaction to all allergen types. It was further concluded that the numbers of children being allergic to just one type of allergen were as follows : house dust 2 (1.8%); human dander 0 (0%), hence all patients allergic to the human dander were also allergic to house dust; fungus 1 (0.9%); collection of animal danders 1 (0.9%); "mite" 2 (1.8%); bacteria 19 (17.3%). The highest incidence of reaction to more than one allergen were to house dust+human dunders: 80 (72. 7%); to house dust+ "mite": 21 (21.91%); and to house dust+human dander +"mite": 17 ( 15.5%).
Tuberculous meningitis at the Department of Child Health Dr. Pirngadi Hospital Medan (1979) Sondang Tambunan; Adi Sutjipto; Rahayu Saat; A. J. Noeriman; Helena Siregar; Bistok Saing
Paediatrica Indonesiana Vol 24 No 7-8 (1984): July - August 1984
Publisher : Indonesian Pediatric Society

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Abstract

A retrospective study on tuberculous meningitis had been carried out on 43 patients at the Department of Child Health, Dr. Pirngadi Hospital Medan during the year 1979. The peak incidence (55.81%) was found in the age group of less than 3 years of which 55.81% was in the second and 44,18% in the third stadium of the disease. Two of the cases were 4 months of age and 1 case was 14 years. None of the cases had got BCG immunization. Mortality rate was 37.21% of which 25% was in the second and 52.63% in the third stadium. Cerebrospinal fluid examination showed that 46.50% had cell counts between 101-500 cells/mm3. The symptoms were prolonged fever (62. 79%), convulsions (72.09%) and unconciousness (27.90%). Of these cases 83.72% had contact with tuberculous patients; 6.9% had positive tuberculin test and 48,83% showed pulmonary involvement on radiological examination. Nutritional status of these cases showed that 48.83% were undernourished and 34.82% were in poor nutritional status.
Gilles de La Tourette's Syndrome Chairul Yoel; A. Afif Siregar; A. H. Sutanto
Paediatrica Indonesiana Vol 24 No 7-8 (1984): July - August 1984
Publisher : Indonesian Pediatric Society

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Abstract

A case of Gilles de Ia Tourette's Syndrome is presented. This is the second reported case in Indonesia. The diagnosis was based on four essential features : childhood onset, multiple motor tics, vocal tics and changing pattern of the symptoms. The exact etiology of this syndrome is still unknown. It is proposed that patients with this illness could have hyperactivity of the dopaminergic systems in their basal ganglia. Symptomatic improvement has been achieved with haloperidol. The response to this drug could not be evaluated in this patient because of refusal to continue the treatment.

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