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Sumatera utara
INDONESIA
Buletin Farmatera
Published by Universitas Muhammadiyah Sumatera Utara
ISSN : 2528410X     EISSN : 2528410X     DOI : -
Core Subject : Health,
Medicine & Pharmacology
Arjuna Subject : -
Articles 10 Documents
 1 
Search results for , issue "Vol 11, No 2 (2026)" : 10 Documents clear
Pengaruh Olahraga Aerobik Low Impact Terhadap Tekanan Darah Dan Denyut Nadi Pada Lansia Di Panti Jompo Tresna Werdha Abdi Binjai Muzhaffar, Dandi Dzaki; Asfur, Robitah
Buletin Farmatera Vol 11, No 2 (2026)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v11i2.26858

Abstract

Abstract: The prevalence of the elderly in Indonesia in 2020 is predicted to be more than 28 million people in the next two years. The elderly group is prone to the occurrence of high blood pressure. Increased blood pressure is a problem that can occur in the event of ageing process. Blood pressure and pulse can be controlled through healthy lifestyle changes, such as exercising. Based on this presentation, the researcher is interested in finding out whether there is an effect of low-impact aerobic exercise on blood pressure and pulse rate in the elderly. This research method is a pre-experimental design with a one-group pretest-posttest design. The design in this study was that there was only one group of interventions, or those who were given treatment. The measuring instrument used to measure is a sphygmanometer. In the Wilcoxon test, systolic blood pressure was found to have a p value of 0.005, diastolic blood pressure was found to have a p value of 0.010, and pulse was found to have a p value of 0.000. In the Wilcoxon test, it is said to have an effect if the p-value: 0.05.  It can be concluded that low-impact aerobic exercise can lower systolic blood pressure and diastolic blood pressure, and can raise the pulse rate of the elderly
Knowledge Level and Personal Hygiene Related To The Incidence of Scabies at Darul Hikmah Islamic Boarding School In Medan City, 2023 Nasution, Ika Yusnasari; Murlina, Nelli
Buletin Farmatera Vol 11, No 2 (2026)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v11i2.26840

Abstract

Abstract: Scabies is an infectious skin disease caused by infestation and sensitization to Sarcoptes scabiei var. hominis and its products. Supporting factors for the occurrence of scabies were poor sanitation, which could attack humans who lived in groups; poor personal hygiene; poor sanitation; low socioeconomic status; and poor behavior that supports health and plays a role in skin diseases. This type of research was an observational analysis with a cross-sectional approach on 253 students at the Darul Hikmah Islamic Boarding School in Medan using the total sampling method. The sample would be given a questionnaire, then the data would be collected and processed using the chi-square test. Univariate analysis obtained the distribution of knowledge levels, mostly good, with as many as 149 people (58.9%) with sufficient personal hygiene, as many as 167 people (66%), and most students do not have scabies, as many as 161 people (63.6%). The results of the analysis using the Chi-Square test showed a relationship between the level of knowledge and personal hygiene on the incidence of scabies, with a value of p = 0.001 (p 0.05). There was a relationship between the level of knowledge and personal hygiene of the students and the incidence of scabies in Pesantren Darul Hikmah, Medan City.
Effectiveness of Fig Leaf Ethanol Extract (Ficus carica L.) As An Antidiabetes In Alloxan-Induced Diabetes Model in Rats Habibie, Muhammad Farhan; Ansyari, Dedi
Buletin Farmatera Vol 11, No 2 (2026)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v11i2.26745

Abstract

Abstract: Long-term use of diabetes mellitus medication can cause several complications, so oter alternative treatments are needed that tend to have safer effects, such as herbal treatments using fig plants. Researchers feel the need to test with different doses and subjects to determine whether fig leaf extract (Ficus carica L.) is effective as an antidiabetic in alloxan-induced diabetic mouse models. This research uses a true experimental method with a pretest-posttest with control group design. Sampling used the simple random sampling method. The samples used were 36 male white rats (Rattus norvegicus L.), which were divided into 6 groups. Data will be analysed using the paired sample T test, one-way ANOVA test, and Post hoc test. The results showed that administering ethanol extract of fig leaves at doses of 200 mg/KgBW, 400 mg/KgBW, and 600 mg/KgBW had effectiveness as an antidiabetic in reducing fasting blood sugar levels in rats induced by alloxan (p = 0.000). However, only the ethanol extract group of fig leaves at a dose of 600 mg/kg bw (P3) had antidiabetic activity that was as effective as the drug glibenclamide (p = 0.253). Administration of ethanol extract of fig leaves (Ficus carica L.) has antidiabetic effectiveness in a rat model of alloxan-induced diabetes.
The Relationship of Maternal Knowledge, Attitude, and Behavior to the Incidence of Atopic Dermatitis in Children as a Prevention Effort at the Sadabuan Village Health Center, Padangsidimpuan City Lubis, Nadhira Amilia Afifi; Hervina, Hervina
Buletin Farmatera Vol 11, No 2 (2026)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v11i2.26707

Abstract

Abstract: Atopic dermatititis (AD) in Indonesia is increasing every year, occupying the first position of the top 10 skin diseases in children. Faktor genetik dan lingkungan berperan dalam DA, menyebabkan kelainan pada sistem kekebalan tubuh dan lapisan kulit epidermis, yang berujung pada hipersensitivitas tipe 2. Padangsidimpuan City has a fairly high incidence rate of dermatitis (27.5%) and a low Pure Participation Rate (APM). Based on this background, given the high prevalence of children, along with low APM, the researcher wanted to conduct his research in the city. This study aims to determine the relationship between the level of knowledge, attitude, and behavior of mothers and the incidence of atopic dermatitis at the Sadabuan Health Center, Padangsidimpuan City, North Sumatra. This research method is observational analytical, where dependent and independent variables are measured, then the data obtained will be analyzed to find the relationship between variables with a cross-sectional approach, where the variables being studied are measured at the same time. The results of the analysis showed the relationship between the mother's level of knowledge and the incidence of AD (p-value: 1.000), the mother's attitude with the incidence of AD (p-value: 0.620), and the mother's behavior with the incidence of AD (p-value: 0.591). There was no relationship between the mother's knowledge, attitude, and behavior on the incidence of atopic dermatitis in children at the Sadabuan Health Center, Padangsidimpuan City.
PERBANDINGAN KADAR HIGH DENSITY LIPOPROTEIN DARAH PADA PEROKOK AKTIF, PEROKOK PASIF, DAN NONPEROKOK Fadillah Pasya, Ryan; Irma, Fani Ade
Buletin Farmatera Vol 11, No 2 (2026)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v11i2.26702

Abstract

Abstract: Tobacco is one of the factors known to increase the risk of disease and premature death globally. Nicotine is one of the harmful substances in cigarettes that can result in the release of hormones such as catecholamines, cortisol, and growth hormone. The release of these hormones can alter the lipid profile in the blood, including increased total cholesterol levels, Very Low-Density Lipoprotein (VLDL), Low Density Lipoprotein (LDL), and decreased High Density Lipoprotein (HDL) levels. This study aims to determine the comparison of HDL levels in active smokers, passive smokers, and non-smokers.  The total sample in this study was 45 people who were divided equally into three different groups, namely active smokers, passive smokers, and non-smokers. Data analysis was processed using SPSS. Research shows there is a difference in HDL levels between active smokers, passive smokers, and nonsmokers (p0.05). Smoking can significantly lower HDL levels in the blood.
PENGARUH LOW IMPACT EXERCISE TERHADAP TINGKAT STRESS LANSIA DI PANTI JOMPO TRESNA WERDHA ABDI BINJAI Andini, Ayu; Asfur, Robitah; Rahmi, Rahmi; Chaniago, Lita Septina
Buletin Farmatera Vol 11, No 2 (2026)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v11i2.27120

Abstract

Abstract: Stress can affect various aspects of life, including physical, psychological and social changes. Ageing and declining health are often associated with mental health conditions such as depression. Increasing physical activity can help reduce stress and improve mental health, especially depression. Aerobic exercise can be beneficial for the elderly, as long as it has the right dosage and design. Aerobic exercise to improve the physical fitness of the elderly uses low-impact exercise. This study aims to determine the influence of exercise on the level of stress of the elderly in the nursing home of Tresna Werdha Abdi Binjai. Pre-experimental design with one group pretest-posttest design. Exercise is carried out for 8 weeks with an exercise duration of around 30 minutes, 3-5 times/week. Sampling was taken using the total sampling method. The data collection technique used the Perceived Stress Scale (PSS) questionnaire, which was taken before and after the exercise intervention. Based on the Wilcoxon Rank Sum Test output, it is known as a value of p=0.000 (p = 0.005), so it can be concluded that there is a significant difference between the pre-test and post-test results after the exercise intervention. There is an influence of low-impact exercise on the stress level of the elderly at the Tresna Werdha ABDI Binjai Nursing Home.
Administration Of Aloe Vera Extract (Aloe Vera L.) Effectively Inhibits The Growth Of The Fungus Malassezia Furfur Causing The Occurrence Of Pythriaasis Versicolor In Vitro Nasution, Nabila Hani; Lubis, Riri Arisanty Syafrin
Buletin Farmatera Vol 11, No 2 (2026)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v11i2.26963

Abstract

Abstract: Pytiriasis versichloror, or better known as panu, is a skin infection caused by a superficial fungus, Malassezia furfur. This disease causes skin discolouration, accompanied by itching in the infected area. Although not contagious, pityriasis versichloror occurs in adolescents or young adults, with risk factors including tropical climate, individual hygiene, environmental factors, age, sex, and genetic factors. Herbal plants, such as aloe vera (Aloe vera L.), have potential as an alternative treatment. Aloe vera has a wide variety of ingredients such as quinones, saponins, aminoglycosides, caffeine, tannins, salicylic acid, flavonoids, synaptic acid, essential oils, and sulfur, some of which have antifungal properties. Previous research has shown that aloe vera extract has an inhibitory effect on the growth of Malassezia furfur fungus. This study aims to determine the effectiveness of giving aloe vera extract (Aloe vera l.) on the growth of the fungus Malassezia furfur, which causes versichloror pityriasis in vitro. This study is an experimental research with a posttest-only control group design. Research shows that the administration of aloe vera extract has a positive impact on inhibiting the growth of Malassezia furfur fungus. Statistical analysis using the Mann-Whitney test confirmed that aloe vera extract effectively inhibited the growth of the fungus. The 90% concentration of aloe vera extract showed the best inhibition effect compared to the concentrations of 80% and 85%. This study shows that aloe vera extract has the potential as an antifungal agent to treat versicolor pityriasis. The 90% concentration of aloe vera extract showed the best inhibition effect, and these findings could be the basis for the development of new therapies in the treatment of versicolor pityriasis using aloe vera extract. 
The Relationship Between Nutritional Status and the Incidence of Soil-Transmitted Helminth Infections in Students of Muhammadiyah Elementary School 19 in Medan Denai District, Medan City Syarbaini, Rara Dhamira; Suryani, Des
Buletin Farmatera Vol 11, No 2 (2026)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v11i2.27200

Abstract

Abstract: Worm infestation (STH) and nutritional status are ongoing health issues in Indonesia. Studies on their relationship are inconsistent, with some reporting a link and others finding none. This study aimed to determine the relationship between nutritional status and STH infection among 68 students at SD 19 Muhammadiyah in Medan City. This was an observational study using a cross-sectional design and total sampling. Nutritional status was determined using the CDC-NCHS 2000 growth curve, and STH infection was diagnosed using the Kato-Katz method. A total of 12 students (out of 68) were found to have an STH infection. Of the infected students, 47% suffered from moderate malnutrition, and 53% were well-nourished. The most prevalent STH species was Ascaris lumbricoides, followed by Trichuris trichiura and Hookworm. The statistical analysis using Fisher’s Exact Test yielded a p-value of 0.203 (p 0.05). The study concluded that there was no significant relationship between STH infection and the nutritional status of the students at 19 Muhammadiyah Elementary Schools.
Latest Pharmacological Therapies in Allergic Rhinitis S Nainggolan, Rudfi Rizky
Buletin Farmatera Vol 11, No 2 (2026)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v11i2.27264

Abstract

Abstract: Allergic rhinitis is a chronic inflammatory disease of the nasal mucosa due to a type 1 hypersensitivity reaction that has a major impact on the quality of life and the global economy. This study aims to review the pathophysiological mechanisms and evaluate the effectiveness of current pharmacological therapies to support more personalized and evidence-based treatment. The method used was a systematic literature review of 2021–2025 publications from the PubMed, Scopus, and Web of Science databases, including clinical studies, meta-analyses, and systematic reviews. Results show that second-generation antihistamines, intranasal corticosteroids, and combination therapies such as GSP301 are effective in controlling symptoms. Additional approaches, such as cromolyn sodium, montelukast, and ipratropium bromide, as well as biologic agents (omalizumab and dupilumab), show promising results, especially in severe or resistant cases. SCIT and SLIT immunotherapies have also been shown to be effective with good safety and compliance profiles. The MASK-air data and the ARIA–EAACI guidelines support a phased and individualized approach to therapy. In conclusion, pharmacological therapy of allergic rhinitis continues to evolve towards more effective, safe, and personalized treatment, with multidisciplinary collaboration as the key to improving patients' quality of life.
Giving Yali Pear Juice (Pyrus Brettschneider) Is Influential Against Total Cholesterol Levels in the Blood in Patients with Hypercholesterolemia Rizkina, Cut Suhaila; Rahmat, Said Munazar
Buletin Farmatera Vol 11, No 2 (2026)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v11i2.27092

Abstract

Abstract: Hypercholesterolemia is one of the abnormalities that occur in the body's metabolism, which is shown to cause an increase in total cholesterol levels exceeding the normal limit, which is 200 mg/dL. Metabolic disorders can increase blood fat levels due to enzyme deficiencies, LDL receptor abnormalities, and genetic factors that trigger excess cholesterol production or decrease cholesterol clearance by the liver. Natural ingredients of fruit can help reduce body fat levels. Yali pears contain compounds such as carotenoids, chlorophyll, triterpenoids, polyphenols, fibre, and vitamin C that can help improve blood lipid profiles. This study looked at the effect of giving Yali pear juice on total cholesterol levels in the blood, so that it can be one of the natural additional treatments for hypercholesterolemia patients. This study uses a non-equivalent control group design, namely research conducted with a pre- and posttest, which is divided into two groups, namely the treatment group given Yali pear juice and the control group given a placebo. Yali pear juice and a placebo were given for 10 days. Checking total cholesterol levels in the blood using GCU easy touch tools before and after the study. Data analysis using the T-test parametric test.  Analysis of pre-test data with the post-test of the treatment group obtained a result of p0.05, which means that there is an effect of Yali pear juice on total cholesterol levels in the blood. In the pre-test with the post-test, the control group had p0.05, which means there was no placebo effect on total cholesterol levels in the blood. Giving Yali pear juice for 10 days has an effect on reducing total cholesterol levels in the blood.

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