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Pharmasipha

pharmasipha
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Published by Universitas Darussalam Gontor

ISSN : 25810820 EISSN : 25809202 DOI : http://dx.doi.org/10.21111/pharmasipha.v5i1.5706

Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

Clinical Pharmacy; Biology Pharmacy; Natural Product Pharmacy; Drug, food and cosmetics analysis; Chemistry Pharmacy; and Islamization of Pharmacy

Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)

Articles 6 Documents

Search results for , issue "Vol 3, No 1 (2019): Maret" : 6 Documents clear

Efektvitas Kombinasi Getah Pelepah Pisang Ambon (Musa paradisiaca L.) dan Jarak Pagar (Jathropha curcas L.) untuk Menyembuhkan Luka pada Marmut (Cavia porcellus) Amal Fadholah; Salma Auliya Fatimah; Salma Cristy Syahidahalla
Pharmasipha : Pharmaceutical Journal of Islamic Pharmacy Vol 3, No 1 (2019): Maret
Publisher : University Of Darussalam Gontor

Wounds are a condition of damage or loss of some body tissue. Wounds can be cured with various drugs but have side effects and long healing times, one of which is Oxytetracyclin 3%. Jatropha sap has tannin, saponin, curcain protease and banana midrib having saponin, lectin, anthraquinone, quinone, flavonoid, tannin compounds which can be used to accelerate the healing process, antibacterial, and stop bleeding. This study aims to determine the effectiveness of the combination of banana stem sap and jatropha curcas to heal wounds in guinea pigs. This study is an experimental type with a completely randomized design (CRD) design using 4 treatments and 2 replications. The treatment used was a combination of banana midrib and jatropha sap with a ratio of 4%: 4%, 8%: 8%, 16%: 16% and positive controls using Oxytetracyclin 3%. The sap of the banana midrib and the distance of the fence are made in the form of ointments. Data in the form of the number of days from the formation of wounds to guinea pigs until the wound heals. The results showed that the combination of jatropha resin and sap of Ambon banana stem can provide the best wound healing effect at a concentration of 16%: 16% with the fastest wound healing time in 6 days.

Uji Efektivitas Ekstrak Etanol Daun Bidara (Ziziphus spina- christi L.) terhadap Pertumbuhan Propionibacterium acne Nurul Marfu’ah; Chelsea Aulia Ramadhani; Aural Miftahul Hasanah
Pharmasipha : Pharmaceutical Journal of Islamic Pharmacy Vol 3, No 1 (2019): Maret
Publisher : University Of Darussalam Gontor

Traditional medicinal plants can prove the importance of natural ingredients for various processes of human medicine. In recent years, there has been an increase in researchers' interest in the use of natural materials as natural biological compounds in the manufacture of drugs. One of the plants used as medicine by the community is bidara plants. Plant bidara contains phenolics and flavonoids which are rich in antibacterial properties. One of the bacteria that causes acne is Propionibacterium acnes. Untrated pimples will cause serious illness. Therefore, this study was conducted to determine the antibacterial activity of the ethanol extract of bidara against Propionibacterium acnes. This is an experimental study with 3 concentrations of bidara leaf extract namely concentrations of 70%, 80%, 90% and using negative controls (aquadest) and positive control (clindamisin). Extract of bidara leaves is done by maceration using 70% ethanol solution. While the antibacterial test uses the agar diffusion method using a well. Data obtained in the form of inhibitory zone measurements were analyzed using Analysis of variants (ANOVA). The results of this study indicate that the ethanol extract of Bidara leaves with a concentration of 70%, 80%, and 90% is not effective in inhibiting the growth of Propionibacterium acnes bacteria.

Pengaruh Jenis Pelarut pada Ekstraksi Daun Kumis Kucing (Orthosiphon stamineus Benth) terhadap Kadar Kalium Janugraheni Prasetya Ningrum; Fitria Susilowati; Lija Oktya Artanti
Pharmasipha : Pharmaceutical Journal of Islamic Pharmacy Vol 3, No 1 (2019): Maret
Publisher : University Of Darussalam Gontor

Indonesia has a variety of biological resources in various regions. One of the plants that can be used as medicine is Orthosiphon stamineus Benth. Orthosiphon stamineus Benth has several secondary metabolites, one of them is Potassium that has diuretic function. This study aims to know the effect of the solvent type to the level of Pottasium on the extraction of Orthosiphon stamineus Benth. The research method was done using atomic absorption spectrophotometry instrument. Samples were obtained and identified from UPT Materia Medica Batu Malang, East Java, sample was extracted by percolation method and infusion. The sample was the destructed then was destructied using HNO3 to transform organic metal into inorganic, then measured the absorbance using atomic absorption spectrophotometry at wavelength 766,5. The result showed that the concentration of potassium in Orthosiphon stamineus Benth in water solvent, ethanol 70%, ethanol 96%, and methanol were (29,256 ± 1,581) mg/L, (51,294 ± 5,028) mg/L, (31,406 ± 2.777) mg/L, (58.351 ± 2.925) mg/L. The method had in standard deviation value of each solvent is; water solvent 0,005, ethanol 70% 0,017, ethanol 96% 0,009, and methanol 0,001. Based on statistical test calculations using different test calculations over two samples there was a difference in average of Potassium level between each solvent, with the highest Potassium content found in methanol solvent.

Implementasi Standar Pelayanan Kefarmasian di Apotek M. Sidrotullah; Nur Radiah
Pharmasipha : Pharmaceutical Journal of Islamic Pharmacy Vol 3, No 1 (2019): Maret
Publisher : University Of Darussalam Gontor

Pharmaceutical work is always developing following the demands of the community so that the patients served understand about the pharmaceutical preparations they receive, and the monitoring system in patients can be carried out well. According to the Minister of Health of the Republic of Indonesia No.73 of 2016, regarding Pharmaceutical Service Standards at the Pharmacy which refers to Pharmaceutical Care, pharmacists are responsible for the quality of medicines given to patients, as well as information on how to use side effects to monitor drug use, to improve quality of life patient. This study aims to determine the description of the implementation of pharmaceutical service standards in pharmacies in the city of Mataram, as well as supporting and inhibiting factors on their implementation. This research is a descriptive study using 52 private pharmacies in 6 sub-districts in the city of Mataram. Data collection was carried out using a questionnaire, referring to Monitoring of Pharmaceutical Services at the Pharmacy, Ministry of Health of the Republic of Indonesia. Assessment includes six standards divided into thirty one parameters. While data on supporting and inhibiting factors are obtained from the results of interviews to respondents. Previously tested the validity and reliability of the questionnaire on 30 respondents using SPSS. The results showed that pharmaceutical service standards at pharmacies in Mataram had not been implemented well, with good categories (≥85) of 0%, medium (65-85) 27%, and less (≤65) 73%. Based on the results of the interview, it is known that the supporting factors for implementing standards are the pharmacist's motivation at work, PSA support and all staff at the pharmacy, support and commitment with relevant stakeholders namely policy makers and regulations, agencies that carry out socialization, monitoring and coaching, universities, professional organizations . While the inhibiting factor is the pharmacist has not played a role in the pharmacy, weak support and evaluation by the pharmacy management, including the procurement of facilities and infrastructure, lack of socialization, legislation, and weak regulatory control by the relevant authorities.

Formulasi Sediaan Tablet Hisap Ekstrak Kering Habbatus Sauda' (Nigella Sativa L.) dengan Kombinasi Sukrosa-Manitol sebagai Bahan Pengisi Yulisa Raras Dewi; Andi Sri Suriati Amal; Lija Oktya Artanti
Pharmasipha : Pharmaceutical Journal of Islamic Pharmacy Vol 3, No 1 (2019): Maret
Publisher : University Of Darussalam Gontor

Habbatus sauda' (Nigella sativa L) has been widely used by Indonesian people with capsule dosage form. In this study the researcher choose the form of suction tablets that aims to provide a form of treatment that can be given easily to children or elderly who are difficult to swallow the drug. This study aims to determine the physical characteristics of dry sucking tablets of habbatus sauda’ extracts with a combination of sucrose - mannitol as a filler material. Habbatus sauda' dried extract is made by water solvent and dried with freeze dryer. Habbatus sauda' dried extract tablet is made in 3 formulations with a combination of sucrose and mannitol namely FI (sucrose 1: manitol 5), FII (sucrose 1: manitol 6) and FIII (sucrose 1: manitol 7). The method of wet granulation is used in the production of dry sucking tablet of habbatus sauda’ dried extract. Granules tested include flow time test, silent angle, compressibility and moisture test. The habbatus sauda' dried extract suction tablets were tested for physical properties including weight uniformity, hardness, friability and tablet disolue time test. Data of granule test result and test of physical properties of tablet were compared with research, while granule flow time test and tablet hardness test were analyzed statistically using One Way ANOVA test with 95% confidence level. The results showed that there was an influence on the hardness and taste of suction tablets of habbatus sauda’ dried extract with a combination of sucrose-mannitol. From the result of the research, it can be concluded that the suction tablet of Habbatus sauda extract with sucrose concentration (1): mannitol (5) has good criteria as suction tablet with tablet hardness 8,57/kg, soluble time 13.27 / minute and 0,12% friability

Uji Efektivitas Perasan Kulit Buah Naga Merah (Hylocereus polyrhizus) dan Jeruk Nipis (Citrus aurantifolia) untuk Mendeteksi Formalin pada Ikan Bandeng (Chanos chanos) Nadia Mira Kusumaningtyas; Baiq Ema Chaeratul Mar’ah; Choirul Umi Haniyah
Pharmasipha : Pharmaceutical Journal of Islamic Pharmacy Vol 3, No 1 (2019): Maret
Publisher : University Of Darussalam Gontor

Milkfish is one of the foods that are rich in protein, making it easy to rot and often preserved. One of the food preservatives used is formalin. Preservation using formalin is not recommended because it can cause damage to the liver and heart. So that in this study an attempt was made to determine the levels of formalin in milkfish so that people do not consume formalin milkfish which is detrimental to their health. Red dragon fruit skin has anthocyanin content which can be used to detect formaldehyde, because anthocyanin will easily react if it is mixed with strong acid so that when it binds with acid, the color of the juice of the dragon fruit skin will become thicker. In this study, the addition of Lime was added because Lime was used as a supporting work for the skin of red dragon fruit. This study was an experiment with 6 treatments and 2 replications. The treatments were (1) dragon fruit skin juice, left for 1 minute (2) dragon fruit skin juice, left for 3 minutes (3) dragon fruit skin juice, left for 5 minutes (4) squeezing dragon fruit skin and lime juice , left for 1 minute (5) squeezing dragon fruit skin and lime juice, left for 3 minutes (6) squeezing dragon fruit skin and lime juice, left for 5 minutes. Color separation in the solution is then recorded as data. The results showed that formalin examination on milkfish using only dragon fruit skin juice gave the results of the formation of complete color separation in the solution at minute 1 (treatment 1). While formalin examination on milkfish uses a combination of squeezing dragon fruit skin and lime giving the results of the formation of color separations and deposits in the solution completely in the 3rd minute (treatment 5). This can illustrate that the juice of dragon fruit skin and a combination of squeezed dragon fruit and lemon juice can be used to detect formalin content in milkfish. The use of dragon fruit skin juice is more effective than a combination of squeezing dragon fruit and lime skin.

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Nurul Marfu'ah

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+6285336431175

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nurulmarfuah@unida.gontor.ac.id

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Location
Kab. ponorogo,

Jawa timur

INDONESIA

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Abstract

Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name Nurul Marfu'ah

Contact Email nurulmarfuah@unida.gontor.ac.id

Phone +6285336431175

Journal Mail Official nurulmarfuah@unida.gontor.ac.id

Editorial Address University Of Darussalam Gontor Gontor For Girls Campus 1, Sambirejo, Mantingan, Ngawi, East Java, Indonesia, 63257

Location Kab. ponorogo, Jawa timur INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Contact Name
Nurul Marfu'ah

Contact Email
nurulmarfuah@unida.gontor.ac.id

Phone
+6285336431175

Journal Mail Official
nurulmarfuah@unida.gontor.ac.id

Editorial Address
University Of Darussalam Gontor Gontor For Girls Campus 1, Sambirejo, Mantingan, Ngawi, East Java, Indonesia, 63257

Location
Kab. ponorogo,

Jawa timur

INDONESIA