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INDONESIA
Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia)
Published by Perkumpulan Obstetri dan Ginekologi Indonesia
ISSN : 23386401     EISSN : 23387335     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology Public Health
The Indonesian Journal of Obstetrics and Gynecology is an official publication of the Indonesian Society of Obstetrics and Gynekology. INAJOG is published quarterly.
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Articles 12 Documents
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Search results for , issue "Volume 11 No. 3 July 2023" : 12 Documents clear
The Effect of Mannihot Esculenta on Prolactin Hormone Levels and Breast Milk Production in Breastfeeding Mothers: Efek Mannihot Esculenta pada Tingkat Hormon Prolaktin dan Produksi Susu Ibu pada Ibu Menyusui Sherin Sausan Wulandari; Krisdiana Wijayanti; Lanny Sunarjo
Indonesian Journal of Obstetrics and Gynecology Volume 11 No. 3 July 2023
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v11i3.1814

Abstract

Objective: To prove the effect of cassava leaves jerky(Mannihot Esculennta) on prolactin hormone levels andbreast milk production in breastfeeding mothers in theWorking Area of the Rejosari Health Center of PekanbaruCity.Methods: This study used True Experiment Design with apretest and posttest design with the control group, usinga simple random sampling with a total of 28 breastfeedingmothers, 14 intervention group respondents, and 14 controlgroup respondents. The intervention group was givencassava leaves jerky 60 gr/day, and the control group wasgiven jerky without cassava leaves 20 gr/day for 2 weeks.Both groups were observed 3 times by weighing the baby'sweight and checking the level of the hormone prolactin afteradministering the intervention using the ELISA method. Dataanalysis using Mann-Whitney, TIndependent, RepeatedANOVA test.Results: There was a difference in the average differenceof prolactin hormone levels in the intervention group andcontrol group with a p-value of 0.000 (<0.05)Conclusion: Giving jerky cassava leaves breast milk boosteraffects the hormone prolactin and breast milk production inbreastfeeding mothers.Keywords: breast milk production, cassava leaves, mannihotesculenta, prolactin.Abstrak Tujuan: Untuk Membuktikan dendeng daun singkong(Mannihot Esculennta) terhadap kadar hormon prolaktindan produksi ASI pada ibu menyusui di Wilayah KerjaPuskesmas Rejosari Kota Pekanbaru.Metode: Penelitian ini menggunakan rancangan percobaanyang sebenarnya dengan desain pretest and posttest onlywith control group, sampling menggunakan sampel acaksederhana dengan jumlah 28 responden ibu menyusui,14 responden kelompok intervensi, dan 14 respondenkelompok kontrol. Kelompok intervensi diberi dendeng daunsingkong 60 gr/hari, dan kelompok kontrol diberi dendengtanpa daun singkong 20 gr/hari selama 2 minggu. Keduakelompok diamati sebanyak 3 kali dengan menimbangberat badan bayi dan pemeriksaan kadar hormon prolaktinsetelah pemberian intervensi dengan metode ELISA. Analisisdata menggunakan uji Mann-Whitney, TIndependent,Repeated ANOVA.Hasil: Terdapat perbedaan rata-rata selisih kadar hormonprolaktin pada kelompok intervensi 376,5 ng/ml, kelompokkontrol 103,5 ng/ml dengan p-value 0,000 (<0,05)Kesimpulan: Pemberian dendeng penambah ASI daunsingkong berpengaruh terhadap hormon prolaktin danproduksi ASI pada ibu menyusui.Kata kunci: daun singkong, mannihot esculenta, produksiASI, prolaktin.
Roma Index and Adnex Model: which is more Superior in Predicting Epithelial Ovarian Malignancy? Index Roma dan Model Adnex: Manakah yang Lebih Unggul dalam Memprediksi Keganasan Ovarium Epitelial? Feibyg Lumandung; Suzanna P. Mongan; Bismarck J. Laihad
Indonesian Journal of Obstetrics and Gynecology Volume 11 No. 3 July 2023
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v11i3.1819

Abstract

Objective: To compare the accuracy of ROMA index andADNEX model in predicting the risk of malignancy in ovariantumour.Methods: This was a prospective analytic study. A total of 37samples were acquired from women of all ages diagnosedwith an ovarian cystic tumour in the Central General HospitalProf. Dr. R. D. Kandou. A CA-125 marker, HE4 marker,menopausal status and ultrasonography (USG) examinationwere obtained, and subsequently compared with the fi nalhistopathological results. The data were analysed by usingthe SPSS statistics software.Results: Thirty-seven women participated in this study. Themean age of participants was 43 years old. The Area UnderCurve (AUC) of the ADNEX was 0.979 with a sensitivity of90.0%, specifi city of 88.2%, negative predictive value of89.8%, and positive predictive value of 80.5%. The AUC ofthe ROMA model was 0.734 with the sensitivity, specifi city,negative predictive value, and positive predictive value of65.0%, 64.7%, 64.8%, and 64.8%, respectively. Both modelsshowed AUC values > 0.50 (p-value < 0.05).Conclusions: The IOTA ADNEX had better accuracy than theROMA model in predicting ovarian epithelial malignancy.The ADNEX model had higher sensitivity and specifi city thanthe ROMA model.Keywords: ADNEX, CA-125, HE4, Ovarian tumour, ROMAAbstrakTujuan: Untuk membandingkan akurasi indeks ROMAdan ADNEX model dalam memprediksi keganasan tumorovariumMetode: Penelitian ini merupakan studi analitik prospektif.Total 37 sampel penelitian didapatkan dari wanita yangdidiagnosa tumor ovarium kistik di RSUP Prof. Dr. R. D.Kandou. CA-125, HE4, status menopause dan pemeriksaanUSG dilakukan, dan dibandingkan dengan hasil histopatologi.Data kemudian dianalisa menggunakan program statistikSPSS.Hasil: Tiga puluh tujuh perempuan yang berpartisipasidalam penelitian ini. Dengan rerata usia 43 tahun. TotalArea Under Curve (AUC) dari IOTA ADNEX adalah 0,979dengan sensitivitas 90,0%, spesifi sitas 88,2%, nilai prediksinegatif 89,8%, dan nilai prediksi positif 80,5%. AUC darimodel ROMA adalah 0,734 dengan sensitivitas, spesifi sitas,nilai prediktif negatif dan nilai predikitif positif 65.0%, 64.7%,64.8%, dan 64.8% berturut-turut. Kedua model menunjukkannilai AUC > 0,50 (nilai p <0,05).Kesimpulan: IOTA ADNEX memiliki akurasi yang lebih baikdibandingkan model ROMA dalam memprediksi keganasanovarium epithelial. ADNEX model memiliki sensitivitas danspesifi sitas lebih tinggi dibandingkan model ROMAKata kunci: ADNEX, CA-125, HE4, ROMA, Tumor Ovarium.
Leiomyoma Ablation with Transvaginal Ultrasonography-Guided Radiofrequency: A Report of Four Cases : Ablasi Mioma dengan Radiofrekuensi Terpandu Ultrasonografi Transvaginal: Laporan Empat Kasus Doddy Sutanto; Ery Surya Sevriana; Rukmono Siswishanto; Lydia Olivia; Rahmalina
Indonesian Journal of Obstetrics and Gynecology Volume 11 No. 3 July 2023
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v11i3.1834

Abstract

Abstract Objective : To perform transvaginal ultrasound-guided radiofrequency ablation (RFA) to four women with symptomatic subserous and intramural leiomyomas using standard protocols. Methods : A report of four cases. Case : This article reports three of four women with leiomyomas had heavy menstruation bleeding. The first case was a premenopausal woman with pelvic discomfort. In the second case, the patient underwent curettage after being diagnosed with a blighted ovum, the third case with non-cyclic pain and irregular cycles, and the fourth case with 14-year-old infertility and repeated IVF failure. No significant side effects or complications occurred after treatment and during observation. Monitoring uterine leiomyoma size for one week and three months showed an average reduction of 56.9%, indicating a significant reduction in myoma volume. The reported symptoms also improved. Conclusion : Transvaginal ultrasound-guided radiofrequency ablation is an effective, non-invasive therapy with minimal side effects, so it may be the primary choice for leiomyoma therapy. Keywords : Leiomyoma, RFA, transvaginal ultrasonography Abstrak Objektif : Untuk melakukan radiofrekuensi ablasi (RFA) terpandu ultrasonografi transvaginal pada empat wanita dengan mioma intramural dan suberosa bergejala dengan menggunakan protokol yang standar. Metode : Laporan empat kasus. Kasus : Melaporkan tigas dari empat wanita dengan mioma uteri mengalami perdarahan menstruasi yang banyak. Kasus pertama adalah seorang wanita premenopause dengan keluhan rasa tidak nyaman pada panggul. Pada kasus kedua, pasien menjalani kuretase setelah didiagnosis dengan blighted ovum, kasus ketiga dengan nyeri non-siklus dan siklus tidak teratur, dan kasus keempat adalah infertilitas 14 tahun dan kegagalan IVF berulang. Tidak ada efek samping yang berarti atau komplikasi yang terjadi setelah tindakan dan selama pemantauan. Pemantauan ukuran mioma uteri selama satu minggu dan tiga bulan menunjukkan penurunan rata-rata sebesar 56,9%, menunjukkan penurunan volume mioma yang signifikan. Gejala-gejala yang dilaporkan juga mengalami perbaikan. Kesimpulan : Radiofrekuensi ablasi terpandu ultrasonografi transvaginal merupakan terapi non-invasif yang efektif dengan efek samping minimal, sehingga dapat menjadi pilihan utama untuk terapi mioma uteri. Kata kunci : Mioma, RFA, ultrasonografi transvaginal
Friedman Curve Positively Correlates with Cesarean Section and Oxytocin Augmentation in Active Phase Delivery as Compared to Partograph: Kurva Friedman Berkorelasi Positif dengan Seksio Sesarea dan Augmentasi Oksitosin pada Fase Aktif Persalinan dibandingkan Partograf Anak Agung Ngurah Anantasika; I Wayan Artana Putra; Ida Bagus Putra Adnyana; I Wayan Megadhana; Ryan Saktika Mulyana; Agustinus Darmawan Hariyanto
Indonesian Journal of Obstetrics and Gynecology Volume 11 No. 3 July 2023
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v11i3.1867

Abstract

Objective: To investigate the correlation between cesareansection and oxytocin augmentation in childbirth monitoredwith the Friedman curve compared to the World HealthOrganization (WHO) partographs.Methods: An analytic cross-sectional study was conductedfrom March to May 2021, involving mothers giving birthwhose delivery process was monitored using either theFriedman curve or the WHO partograph (n=28 for eachgroup) at Wangaya Hospital in Denpasar City. The durationof the active phase until delivery, occurrence of cesareansection, and administration of oxytocin augmentationwere assessed using the Friedman curve and the WHOpartograph. The normality of the data was tested using theKolmogorov-Smirnov test, and the Spearman correlationtest was employed to measure the direction and strengthof the correlation.Results: There was no signifi cant difference between thegroups in terms of monitoring the active phase until deliveryusing the Friedman curve compared to the WHO partograph(p=1.000 > 0.05). Maternal monitoring with the Friedmancurve showed a positive correlation with the occurrenceof cesarean section compared to the WHO partograph(r=0.296, p=0.027). Additionally, monitoring childbirth withthe Friedman curve exhibited a positive correlation with theadministration of oxytocin augmentation compared to theWHO partograph (r=0.298, p=0.026).Conclusion: The fi ndings suggest a stronger positivecorrelation between the incidence of cesarean section andthe administration of oxytocin augmentation in childbirthmonitored with the Friedman curve compared to the WHOpartograph.Keywords: cesarean section, Friedman curve, oxytocinaugmentation, WHO partograph.AbstrakTujuan: Untuk menentukan korelasi antara operasi sesardan augmentasi oksitosin pada persalinan yang dipantaudengan kurva Friedman dibandingkan dengan partografOrganisasi Kesehatan Dunia (WHO).Metode: Desain penelitian analitik potong lintangdilakukan pada Maret-Mei 2021, dengan melibatkan ibubersalin yang proses persalinannya dipantau menggunakankurva Friedman atau Partograf WHO (n=28 untuk setiapkelompok) di ruang bersalin di Rumah Sakit Wangaya,Kota Denpasar. Waktu fase aktif hingga kelahiran bayi,persalinan seksio sesarea, dan augmentasi oksitosin dinilaidengan menggunakan kurva Friedman dan Partograf WHO.Uji normalitas dilakukan dengan uji Kolmogorov-Smirnov,dilanjutkan dengan uji korelasi Spearman untuk mengukurarah dan kekuatan korelasi.Hasil: Pemantauan ibu bersalin dengan kurva Friedmandibandingkan dengan Partograf WHO dalam hal faseaktif-persalinan bayi menunjukkan tidak ada perbedaanyang signifi kan di antara kedua kelompok (p = 0,000 >0,05). Pemantauan ibu dengan kurva Friedman berkorelasipositif dengan kejadian bedah sesar dibandingkandengan Partograf WHO (r = 0,296, p = 0,027). Selain itu,pemantauan persalinan dengan kurva Friedman berkorelasipositif dengan pemberian oksitosin dibandingkan denganpartograf WHO (r = 0,298, p = 0,026).Kesimpulan: Terdapat korelasi positif yang lebih tinggiantara kejadian bedah sesar dan pemberian augmentasioksitosin pada proses persalinan yang dipantau dengankurva Friedman dibandingkan dengan partograf WHO.Kata kunci: augmentasi oksitosin, kurva friedman, partografWHO, seksio sesarea
Granisetron was more Effective than Ondansetron as Antiemetic in Ovarian Cancer Patients: a Randomized Controlled Trial: Granisetron Lebih Efektif Dibandingkan Ondansetron Sebagai Antiemetik Pada Pasien Kanker Ovarium: Penelitian Uji Acak Terkendali Hanif Reza; Shinta Prawitasari; Ardhanu Kusumanto
Indonesian Journal of Obstetrics and Gynecology Volume 11 No. 3 July 2023
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v11i3.1877

Abstract

Objective: To determine the effectiveness of intravenousinjection of granisetron compared to ondansetron inpreventing nausea and vomiting, we used the MASCCAntiemesis Tool (MAT) in ovarian cancer patients undergoingpaclitaxel-carboplatin chemotherapyMethods: This study was conducted as a double-blind,randomized controlled trial. The treatment group received1 mg of granisetron, whereas the control group received8 mg of ondansetron intravenously. Nausea and vomitingwere assessed using the MAT scale at 12 hours, 24 hours,and 48 hours after chemotherapy. The differences in MATscores between the groups were analyzed using the Mann-Whitney test.Results: A total of 60 participants were enrolled in thisstudy. The results indicated that the MAT score at the 12-hour mark significantly differed from the 24-hour and 48-hour MAT scores (p = 0.00, p = 0.00). The MAT scores in thegranisetron group at 12 hours, 24 hours, and 48 hours werestatistically lower compared to the ondansetron group (p =0.00, p = 0.00, p = 0.00).Conclusions: In conclusion, intravenous granisetron provedto be more effective than intravenous ondansetron inpreventing nausea and vomiting among patients with ovariancancer undergoing paclitaxel-carboplatin chemotherapy.Keywords: chemotherapy, granisetron, MAT score,ondansetron, ovarian cancer.AbstrakTujuan: Mengetahui efektivitas perbandingan pemberianinjeksi intravena antara granisetron dan ondansetrondalam mencegah mual dan muntah dengan menggunakanMAT pada pasien dengan kanker ovarium yang mendapatkemoterapi dengan regimen paclitaxel-carboplatin.Metode: Penelitian ini merupakan double blind randomizedcontrolled trial dengan kelompok perlakuan diberikangranisetron 1 mg dan kelompok kontrol yang diberikaninjeksi ondansetron 8mg. Kemudian dilakukan penilaianterhadap mual dan muntah dengan menggunakan skorMAT pada 12 jam, 24 jam, dan 48 jam setelah diberikankemoterapi dengan menggunakan Mann-Whitney testkarena distribusi data tidak normal.Hasil: Total sampel pada penelitian ini adalah 60 subjek.Hasil skor MAT pada 12 jam berbeda bermakna dengan skorMAT 24 jam dan skor MAT 48 jam (p= 0,00, p= 0,00. Terdapatperbedaan bermakna secara statistik pada pengaruh terapigranisetron dan ondansetron terhadap skor MAT 12 jam, 24jam, dan 48 jam (p= 0,00, p= 0,00, p= 0,00).Kesimpulan: Pemberian injeksi granisetron intravena lebihefektif mencegah mual dan muntah dengan menggunakanMAT dibandingkan dengan injeksi ondansetron intravenapada pasien dengan kanker ovarium yang mendapatkemoterapi paclitaxel-carboplatin.Kata kunci: kemoterapi, granisetron, kanker ovarium,ondansetron, skor MAT.
The Role of Probiotics in Urinary Tract Infections in Women: Peran Probiotik dalam Infeksi Saluran Kemih pada Perempuan Kurniawati, Eighty Mardiyan; Gatut Hardianto; Setyo Hadi, Tri Hastono; Paraton, Hari; Widyasari, Anis; Rahmawati, Nur Anisah
Indonesian Journal of Obstetrics and Gynecology Volume 11 No. 3 July 2023
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v11i3.1881

Abstract

Objective: To review the role of probiotics in urinary tractinfections in womenMethods: Systematic review was conducted by searchingfi ve databases with several keywords, namely “urinary tractinfection”, “cystitis”, “women” and “probiotics”. Articles thathave gone through peer review are included in the studyif they meet the inclusion and exclusion criteria. Reportingfollows the PRISMA rules.Results: The women included in this study varied from earlyadulthood to postmenopausal, most of whom were sexuallyactive, used birth control methods, and had recurrenturinary tract infections. The results showed that the use ofprobiotics in varied outcomes, either positive or not showedsignifi cant results. This is also due to the differences in theoutcomes studied and the additional materials used. Thisalso contributed to the emergence of adverse effects.Conclusion: The use of probiotics in the treatment ofcystitis and urinary tract infections has hope, although notall studies show signifi cant results. The side effects foundare still tolerable although they need to be considered.Keywords: cystitis, probiotic, urinary tract infection, women.AbstrakTujuan: Meninjau peran probiotik dalam infeksi salurankemih pada perempuan.Metode: Tinjauan sistematis dilakukan dengan mencari limadatabase dengan beberapa kata kunci, yaitu “infeksi salurankemih”, “sistitis”, “perempuan” dan “probiotik”. Artikel yangtelah melalui peer review diikutsertakan dalam penelitianjika memenuhi kriteria inklusi dan eksklusi. Pelaporanmengikuti aturan PRISMA.Hasil: Perempuan yang diikutsertakan dalam penelitian inibervariasi mulai dari dewasa awal hingga pascamenopause,sebagian besar aktif secara seksual, menggunakan metodekontrasepsi, dan mengalami infeksi saluran kemih berulang.Hasil penelitian menunjukkan bahwa penggunaan probiotikpada infeksi saluran kemih menunjukkan hasil yang positifmaupun tidak menunjukkan hasil yang signifi kan. Hal inijuga disebabkan perbedaan outcome dan bahan tambahanyang digunakan. Penggunaan bahan juga berkontribusipada munculnya efek samping.Kesimpulan: Penggunaan probiotik dalam pengobatansistitis dan infeksi saluran kemih memiliki harapan, walaupuntidak semua penelitian menunjukkan hasil yang signifi kan.Efek samping yang ditemukan masih dapat ditoleransimeskipun perlu diperhatikan.Kata kunci: infeksi saluran kemih, perempuan, probiotik,sistitis.
Management of Spontaneous Cornual Heterotopic Pregnancy in Low-Resources Setting: Tata Laksana Kehamilan Heterotopik Kornual Spontan pada Keadaan Sumber Daya Terbatas Jacklyn Yosefin Gracia Lubis; Yosep Sutandar; Lidya F. Nembo
Indonesian Journal of Obstetrics and Gynecology Volume 11 No. 3 July 2023
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v11i3.1883

Abstract

Objective: To report management of spontaneous cornualheterotopic pregnancy in low-resources setting in EndeDistrict, Flores, East Nusa Tenggara.Methods: Case report.Case: A 34 year old primigravida with history of 8-9 weeksamenorrhea came to Obstetrics ER with chief complaintof vaginal bleeding and lower abdominal pain. Ultrasoundshows intrauterine pregnancy (IUP), an ectopic pregnancy(EP) in right uterine cornu, and free fl uid in hepatorenalspace, splenorenal space, and pouch of douglas suggestingthe occurrence of hemoperitoneum and heterotopicpregnancy. We performed cornual resection by laparotomyand administered progesterone orally before and after thesurgery. Successful outcome was achieved.Discussion: Heterotopic pregnancy (HP) rarely occurs,especially in natural conception. Thus, early diagnosis andtreatment of HP are quite a challenge for physicians especiallyin rural area. Due to the condition of our patient and limitedresources, laparotomy was conducted to remove the EP,rather than laparoscopy despite its advantage to lower riskof IUP abortion. Progesterone was then administered orallyto prevent threatened abortion of the IUP.Conclusion: Despite its challenge in diagnosing andtreating HP, it is a life-threatening condition that requiresaccurate and prompt treatment. The treatment goal is toremove the EP and preserve the IUP. Treatment of choiceshould be decided by takeing the patient’s condition andavailability of resources into account. Surgical along withadministration of progesterone before and after the surgerywould likely improve the outcome of the patient and theintrauterine pregnancy.Keywords: cornual resection, heterotopic pregnancy,laparotomy, low-resources setting, progesterone.AbstrakTujuan: Untuk membahas tentang penatalaksanaankehamilan heterotopik kornu spontan di daerah dengansumber daya rendah khususnya di Kabupaten Ende, Flores,Nusa Tenggara Timur.Metode: Laporan KasusKasus: Seorang perempuan primigravida usia 34 tahundengan riwayat amenore minggu ke-8 dan 9 datang keIGD Obgyn dengan perdarahan pervaginam dan nyeriperut bagian bawah. Temuan USG menunjukkan kehamilanintrauterin (KIU), kehamilan ektopik (KE) di tanduk rahimkanan, dan cairan bebas di ruang hepato-renal, splenorenal,dan cavum douglas. Hal ini menunjukkan terjadinyahemoperitoneum dan kehamilan heterotopik. Reseksikornu dengan laparotomi dilakukan dan pasien diberikanprogesteron secara oral sebelum dan setelah operasi.Luaran baik berhasil dicapai.Diskusi: Kehamilan heterotopik jarang terjadi, terutamapada konsepsi alami. Sehingga diagnosis dan tata laksanaKH sejak dini menjadi tantangan bagi para dokter, terutamadi daerah terpencil Karena kondisi pasien dan sumber daya,laparotomi dilakukan untuk mengangkat KE, daripadalaparoskopi meskipun keuntungannya dalam menurunkanrisiko keguguran KIU. Progesteron kemudian diberikansecara oral untuk mencegah terjadinya keguguran terancamdari KIU.Kesimpulan: Terlepas dari tantangan untuk diagnosisdan tatalaksananya, KH adalah kondisi yang mengancamjiwa yang membutuhkan penanganan yang akurat dansegera. Tujuan tatalaksananya adalah untuk mengangkatKE dan mempertahankan KIU. Pilihan tata laksana harusdiputuskan dengan mempertimbangkan kondisi pasien danketersediaan sumber daya. Pendekatan bedah dan obatdengan progesteron yang diberikan sebelum dan sesudahoperasi akan meningkatkan kemungkinan luaran pasien dankehamilan intrauterine yang baik.Kata kunci: kehamilan, heterotopik, laparotomi,progesteron,reseksi kornual, sumber daya rendah.
The Role of Vitamin D in Pregnant Women in Birth Weight of Neonates: Peran Vitamin D pada Ibu Hamil terhadap Berat Badan Lahir Neonatus Rajuddin Rajuddin; Derevie Hendryan Moulina; Munawar; Cut Meurah Yeni; Hilwah Nora
Indonesian Journal of Obstetrics and Gynecology Volume 11 No. 3 July 2023
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v11i3.1896

Abstract

Objective: To determine the relationship between serumvitamin D levels in third trimester mothers and newbornbirthttweight.Method: The study was conducted at the maternity wardof Dr. Zainoel Abidin General Hospital in Banda Aceh,Indonesia. Maternal and infant serum vitamin D levelswere measured using the Automatic ChemiluminescenceImmunoassay Analyzer (CLIA) method. Blood samples werecollected from mothers in the third trimester and frominfants after delivery. Spearman's correlation rank test wasemployed with a confi dence level of 95%. Vitamin D levelswere categorized as suffi cient, insuffi cient, and defi cient.Results: A total of 39 pregnant women with an averageage of 30.38 ± 6.21 years participated in the study, with apredominance of 38-39 weeks of gestation (35.9%). Themean vitamin D levels in mothers and neonates were 17.4ng/mL and 17.6 ng/mL, respectively (p = 0.003, R = 0.462).The average birth weight of the babies was 3,100 grams,ranging from 2,100 grams to 4,200 grams (p = 0.185, R =0.217). Both variables showed a positive correlation withvarying strength of the relationship.Conclusion: Maternal serum vitamin D levels in the thirdtrimester exhibited a positive correlation with serum vitaminD levels in neonates with moderate strength, but therewas no correlation with birth weight. The evaluation ofmaternal third-trimester serum vitamin D levels can serve asa predictor of neonatal vitamin D levels.Keywords: birth weight, neonates, pregnancy, vitamin D. AbstrakTujuan: Untuk menilai pengaruh hubungan kadar vitaminD serum ibu trimester ketiga terhadap kadar vitamin D danberat badan neonatus yang dilahirkan.Metode: Penelitian ini studi observasional korelatif dengandesain potong lintang yang dilakukan pada kamar bersalinRSUD dr. Zainoel Abidin Banda Aceh. Pengukuran kadarvitamin D serum ibu dan bayi dilakukan dengan metodeAutomatic Chemiluminescence Immunoassay Analyzer(CLIA). Analisis data dengan melakukan Uji Spearman’scorrelation rank test untuk menilai kekuatan hubungan duavariabel.Hasil: Sebanyak 39 ibu hamil usia 30,38 ± 6,21 tahun terlibatdalam penelitian ini dengan dominasi usia kehamilan 38–39minggu (35,9%). Rerata kadar vitamin D ibu dan bayi secaraberurutan adalah 17,4 ng/mL dan 17,6 ng/mL (p = 0,003,R = 0,462). Rerata berat badan bayi yang dilahirkan adalahsebesar 3.100 gram dengan rentang 2.100 gram hingga4.200 gram (p = 0,185, R = 0,217). Kedua variabel didapatkankorelasi positif dengan kekuatan hubungan bervariasi.Kesimpulan: Kadar vitamin D serum ibu trimester ketigaberkorelasi positif terhadap kadar vitamin D serum neonatusyang dilahirkan dengan kekuatan sedang namun tidakberkorelasi terhadap berat badan lahir bayi. Kadar vitaminD serum ibu pada trimester ketiga dapat dijadikan prediktorkadar vitamin D neonatus saat dilahirkan.Kata kunci: berat badan lahir, kehamilan, neonatus,vitamin D.
Neuroendocrine Cervical Carcinoma: Karsinoma Serviks Neuroendokrin Yulian Prastisia; Adrian Djatikusumo; Wina Kanya Wasystha; Iwan Kurnia Effendi
Indonesian Journal of Obstetrics and Gynecology Volume 11 No. 3 July 2023
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v11i3.1898

Abstract

Objective: To present a series of neuroendocrine cervical carcinoma, a rare malignancy of the cervix with different stages, treatment approach and outcome. It is included in this article review about diagnostic approach, treatment and prognosis in dealing with neuroendocrine cervical carcinoma. Methods: Case report Cases: We reported three cases of neuroendocrine cervical carcinoma. First is a 40-year old woman para 2, with stage IIIB neuroendocrine cervical carcinoma and chose palliative care only. Second, a 54-year old woman, para 5 with stage IIB neuroendocrine cervical carcinoma which underwent radiotherapy, with a 4 months disease free period. And lastly, a 36-year old woman, para 2 with stage IB1 neuroendocrine cervical carcinoma, underwent a radical abdominal hysterectomy procedure with pelvic lymphadenectomy and external pelvic radiotherapy. The disease is well controlled and had no recurrence in 15 years. Conclusion: It is important to differentiate neuroendocrine cervical carcinoma with other malignancies that could be found in the cervix. Immunohistochemistry (IHC) tests could be used to achieve that purpose. It is also important to arrange a treatment plan to treat these malignancies and multimodality treatment is preferable for better outcomes. Keywords: Neuroendocrine cervical carcinoma, cervical carcinoma, multimodality treatment.AbstrakTujuan: Melaporkan serangkaian kasus neuroendocrinecervical carcinoma, salah satu jenis keganasan langka padaarea serviks dengan stadium, tata laksana, dan hasil yangberbeda. Dalam artikel ini juga terdapat ulasan mengenaiprosedur diagnosis, manajemen, dan prognosis darineuroendocrine cervical carcinoma.Metode: Laporan kasusKasus: Artikel ini melaporkan tiga kasus. Pertama perempuan40 tahun riwayat partus dua kali dengan karsinoma serviksneuroendokrin stadium IIIB dan hanya memilih perawatanpaliatif. Kasus kedua, perempuan 54 tahun, riwayat partuslima kali dengan karsinoma serviks neuroendokrin stadiumIIB. Pada pasien dilakukan terapi radiasi dan didapatkankondisi bebas penyakit selama 4 bulan. Terakhir, pasienperempuan 36 tahun riwayat partus dua kali dengankarsinoma serviks neuroendokrin stadium 1B1. Dilakukanhisterektomi radikal dan limfadenektomi kelenjar limfepelvis serta terapi radiasi. Kondisi pasien terkontrol dantidak terdapat kekambuhan setelah 15 tahun.Kesimpulan: Karsinoma serviks dengan jenis neuroendokrinharus dibedakan dengan keganasan lain pada daerah serviks.Uji imunohistokimia dapat digunakan untuk membedakanhal tersebut. Selain itu, penyusunan rencana tatalaksanauntuk mengatasi keganasan pada serviks juga harusmenjadi perhatian penting bagi klinisi. Direkomendasikanuntuk menerapkan tata laksana multimodal untuk mencapaihasil terapi yang optimal.Kata kunci: karsinoma serviks, karsinoma serviksneuroendokrin, tata laksana multimodal.
The Effect of Water Intake during Pregnancy on Birth Weight: Pengaruh Asupan Air selama Kehamilan pada Berat Lahir Bayi Tria Rosemiarti; Hardinsyah Hardinsyah; Budi I. Santoso; Sudung O. Pardede; Parlindungan Siregar; Netta M. Putri; Ratu S. Hanifah
Indonesian Journal of Obstetrics and Gynecology Volume 11 No. 3 July 2023
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v11i3.1963

Abstract

AbstractObjective: This systematic review aimed to investigate theeffect of water intake during pregnancy on infant birthweight.Methods: A comprehensive search was conducted usingthe keywords "water intake," "dehydration," "pregnancy,""outcome," "hydration," "birth weight," and "birth outcome"in databases such as "SCOPUS," "EBSCO," "PUBMED,""COCHRANE," and through "Google Search." MeSH headings"pregnancy" and "hydration" were used for the search.Inclusion criteria encompassed pregnant women withoutpathological disorders, birth weight as a studied outcome,prospective cohorts, clinical trial study designs, and Englishlanguagepapers. Out of the 254 articles retrieved, six metthe specifi ed requirements and were included in this review.Results: The fi ndings from the six studies consistentlydemonstrated a positive correlation between higher waterintake, improved hydration, and increased birth weight.All studies measured water consumption or hydrationstatus between 8-37 weeks of gestation. Regardless of theduration of the studies, underhydration or low water intakewas consistently associated with lower birth weight.Conclusion: This review highlights that increasing waterintake among pregnant women positively affects infantbirth weight. Adequate water intake during pregnancy isrecommended to be in the range of 2180 – 3000 mL daily,considering hydration status and the stage of pregnancy.Keywords: birth weight, hydration, pregnancy, water intake.AbstrakTujuan: Untuk mengungkap pengaruh asupan air selamakehamilan terhadap berat lahir bayi.Metode: Menggunakan kata kunci “water intake,""dehydration," "pregnancy," "outcome," "hydration," "birthweight," dan "birth outcome,", artikel dicari. Data diambil daridatabase "SCOPUS," "EBSCO," "PUBMED," "COCHRANE,"dan "Google Search". Kami menggunakan MeSH headingskehamilan dan hidrasi untuk istilah pencarian. Kriteria inklusiadalah perempuan hamil tanpa kelainan patologis, beratbadan lahir adalah salah satu luaran penelitian, desain studiberupa kohort prospektif dan uji klinis, serta artikel dalambahasa Inggris. Dari 254 artikel yang diperoleh, enam artikelmemenuhi persyaratan dan digunakan untuk review ini.Hasil: Dari keenam penelitian menunjukkan bahwa semakintinggi asupan air, semakin baik hidrasi atau asupan airmeningkatkan berat bayi lahir. Semua penelitian mengukurkonsumsi air atau status hidrasi antara 8-37 minggu. Studistudiini secara konsisten memberikan bukti bahwa asupanair yang rendah atau kondisi kekurangan cairan dikaitkandengan berat badan lahir rendah, terlepas dari durasi studi.Kesimpulan: Kajian ini menunjukkan bahwa peningkatanasupan air ibu hamil berpengaruh positif terhadap beratlahir bayi. Asupan air yang cukup pada ibu hamil adalah2180 – 3000 mL setiap hari bergantung pada status hidrasidan usia kehamilan.Kata kunci: asupan air, berat lahir, hidrasi, kehamilan.

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