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INDONESIA
Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia)
Published by Perkumpulan Obstetri dan Ginekologi Indonesia
ISSN : 23386401     EISSN : 23387335     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology Public Health
The Indonesian Journal of Obstetrics and Gynecology is an official publication of the Indonesian Society of Obstetrics and Gynekology. INAJOG is published quarterly.
Arjuna Subject : -
Articles 1,731 Documents
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Diagnosis and Management of Severe Peripartum Cardiomyopathy: Diagnosis dan Manajemen Kardiomiopati Peripartum Berat Sidhi Laksono; Ananta S. Prawara; Reynaldo Halomoan
Indonesian Journal of Obstetrics and Gynecology Volume 9 No. 4 October 2021
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v9i4.1459

Abstract

Objective: To describe the diagnosis and management of severe peripartum cardiomyopathyMethods: A case report.Case: A 35-year-old woman presented with dyspnea and leg edema. The patient gave birth 3 months ago. The hemodynamic was unstable and the physical examination showed a mild rhonchi in the basal of the lung and pansystolic murmur in the apex. Echocardiography showed a dilated heart chamber and reduced ejection fraction (30%). The patient was diagnosed as severe PPCM. The initial management was to stabilize the patient using furosemide, catecholamine, and vasopressor administration. After the patient’s condition was stable, ramipril, bisoprolol, and bromocriptine were given as heart failure therapy.Conclusions: Patient with suspicion of PPCM should be managed thoroughly from detailed history taking to proper diagnostic testing such as echocardiography. Prompt treatment of severe PPCM according to the guideline will improve the cardiac function.Key words: catecholamines, echocardiography, peripartum cardiomyopathy, pregnancy, vasopressor. Abstrak Tujuan: Untuk mendeskripsikan mengenai diagnosis dan manajemen pasien pada kasus kardiomiopati peripartum yang berat.Metode: Laporan kasus.Kasus: Seorang Perempuan 35 tahun datang dengan dispnea dan edema tungkai. Pasien melahirkan 3 bulan lalu. Hemodinamik tidak stabil dan pemeriksaan fisik menunjukkan ronki ringan di basal paru dan murmur pansistolik di apeks. Ekokardiografi menunjukkan dilatasi ruang jantung dan fraksi ejeksi berkurang (30%). Pasien didiagnosis dengan PPCM berat. Penatalaksanaan awal adalah menstabilkan pasien dengan pemberian furosemid, katekolamin, dan vasopresor. Setelah kondisi pasien stabil, diberikan ramipril, bisoprolol, dan bromokriptin sebagai terapi gagal jantung.Kesimpulan: Pasien dengan kecurigaan PPCM harus dikelola secara menyeluruh mulai dari anamnesa yang rinci hingga uji diagnostik yang tepat seperti ekokardiografi. Pengobatan segera untuk PPCM derajat berat yang sesuai dengan pedoman akan meningkatkan fungsi jantung.Kata kunci: ekokardiografi, kardiomiopati peripartum, katekolamin, kehamilan, vasopressor.
Interaction of Physical Activity and Body Mass Index with Age at Menarche : Interaksi Aktivitas Fisik dan Indeks Massa Tubuh dengan Usia Menarche Filsa P. Anwar; Hilwah Nora; Muhammad Ridwan
Indonesian Journal of Obstetrics and Gynecology Volume 9 No. 4 October 2021
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v9i4.1498

Abstract

Objective: To investigate the interaction of physical activity and body mass index with age at menarche in Babun Najah Junior High School.Methods: This was a cross sectional study. The sampling technique in this study is non-probability sampling by a total sampling.Results: The results of the study were processed using the Chi-Square statistical test on 142 samples, obtained p-value = 0.748 (p>0.05) for the relationship between physical activity and age at menarche, p-value = 0.048 (p<0.05) for relationship between body mass index with age at menarche, and p-value > 0.05 for the interaction of physical activity and body mass index with age at menarche.Conclusions: There is no interaction of physical activity and body mass index with age at menarche in Babun Najah Junior High School.Keywords: body mass index, interaction, menarche age, physical activity. Abstrak Tujuan: Mengetahui interaksi aktivitas fisik dan indeks massa tubuh dengan usia menarche di Madrasah Tsanawiyah Swasta Babun Najah.Metode: Jenis penelitian ini adalah observasional analitik dengan desain penelitian potong lintang. Teknik pengambilan sampel dalam penelitian ini adalah pengambilan sampel non probabilitas dengan metode total sampling.Hasil: Terdapat hubungan antara indeks massa tubuh dengan usia menarche (p-value = 0,048) , tidak terdapat hubungan antara aktivitas fisik dengan usia menarche (p-value = 0,784) serta tidak terdapat interaksi antara aktivitas fisik dan indeks massa tubuh dengan usia menarche (p-value > 0,05).Kesimpulan: Tidak terdapat interaksi aktivitas fisik dan indeks massa tubuh dengan usia menarche di Madrasah Tsanawiyah Swasta Babun Najah.Kata kunci: aktivitas fisik, indeks massa tubuh, , interaksi, usia menarche
Role of Maternal Factors in Low Birth Weight: Peran Faktor Ibu dalam Kejadian Berat Bayi Lahir Rendah Gita S. Candijaya; Edihan Mardjuki; Edward Surjono
Indonesian Journal of Obstetrics and Gynecology Volume 9 No. 4 October 2021
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v9i4.1513

Abstract

Objective : To determine the correlation between body mass index, age, parity, gestational weight gain and low birth weight at Atma Jaya Hospital in 2016-2019.Methods : This was a cross-sectional study of 111 sample medical records of pregnant women who gave birth at Atma Jaya Hospital in 2016-2019 and met the inclusion and exclusion criteria. Data management was performed using the Chi-square test and multivariate logistic regression test.Results: Most of the mothers were in the group with normal BMI (60.4%), the G1 age group (21-29 years old) (45.9%), the low multiparity group (parity 1-3 times) (57.7%). The analysis showed that there was a significant relationship between parity group grand multipara (p=0.028; OR=5.206; 95% CI=1.195-22.686) with the incidence of LBW. There was no significant relationship between BMI group lean (p=0.303; OR=1.646; 95% CI=0.638-4.246), group normal (p=0.532), group fat (p=0.440; OR=1.957; 95% CI=0.357-10.737), maternal age group G1 (p=0.141), group G2 (p=0.587; OR=1.327; 95% CI=0.478-3.687), group G3 (p=0.111; OR=0.262; 95% CI=0.050-1.360), parity group nulliparity (p=0.494; OR=0.669; 95% CI=0.212-2.117), group low multiparity (p=0.051), and gestational weight gain group low (p=0.955; OR=1.028; 95% CI=0.396-2.667), group normal (p=0.986), group high (p=0.897; OR=0.917; 95% CI=0.245-3.424) with the incidence of LBW.Conclusion : There is a significant relationship between parity with the incidence of low birth weight. There is no relationship between body mass index, age, and gestational weight gain with the incidence of low birth weight.Keywords: age, BMI, gestational weight gain, LBW, parity. Abstrak Tujuan: Mengetahui apakah terdapat hubungan antara indeks massa tubuh, usia, paritas, dan pertambahan berat badan ibu hamil terhadap kejadian berat bayi rendah di Rumah Sakit Atma Jaya tahun 2016-2019.Metode: Penelitian ini merupakan penelitian analitik potong lintang dengan menggunakan rekam medis sebanyak 111 sampel ibu hamil yang melangsungkan persalinan di RS Atma Jaya pada tahun 2016-2019 dan memenuhi kriteria inklusi dan eksklusi. Pengelolaan data dilakukan dengan menggunakan uji Chi-square dan uji regresi logistik multivariat.Hasil : Didapatkan sebagian besar ibu berada pada kelompok dengan indeks massa tubuh normal (60,4%), kelompok usia G1 (21-29 tahun) (45,9%), kelompok paritas low multiparity (paritas 1-3 kali) (57,7%), dan kelompok pertambahan berat badan normal (47,7%). Hasil analisis menunjukkan terdapat hubungan antara paritas kelompok grand multipara (p=0,028; OR=5,206; 95% CI=1,195-22,686) terhadap kejadian BBLR. Tidak terdapat hubungan signifikan antara indeks massa tubuh kelompok kurus (p=0,303; OR=1,646; 95% CI=0,638-4,246), kelompok normal (p=0,532), kelompok gemuk (p=0, 440; OR=1, 957; 95% CI=0, 357-10.737), usia ibu hamil kelompok G1 (p=0,141), kelompok G2 (p=0,587; OR=1,327; 95% CI=0,478-3,687), usia kelompok G3 (p=0,111; OR=0,262; 95% CI=0, 050-1,360), paritas kelompok nulliparity (p=0,494; OR=0,669; 95% CI=0,212-2,117), kelompok low multiparity (p=0.051), pertambahan berat badan ibu hamil kelompok kurang (p=0.955; OR=1.028; 95% CI=0.396-2.667), kelompok sesuai (p=0.986), dan kelompok lebih (p=0.897; OR=0.917; 95% CI=0.245-3.424) dengan kejadian BBLR.Kesimpulan : Terdapat hubungan yang signifikan antara paritas dengan kejadian berat bayi lahir rendah. Tidak terdapat hubungan antara indeks massa tubuh, usia, dan pertambahan berat badan ibu hamil dengan kejadian berat bayi lahir rendah.Kata kunci: BBLR, IMT, paritas, pertambahan berat badan, usia.
Maternal and Perinatal Outcomes of COVID-19 in Pregnant Women : Luaran Maternal dan Perinatal pada Ibu Hamil dengan COVID-19 Putu H. I. Pramana; Gede B. S. Wirawan; Made Y. D. Astiti; Kaspan
Indonesian Journal of Obstetrics and Gynecology Volume 9 No. 4 October 2021
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v9i4.1532

Abstract

Objective: To describe and identify risk factors of maternal and perinatal outcome of COVID-19 in pregnant women.Methods: Literature search was conducted on MEDLINE and Google Scholar databases for articles published in December 2020 to January 2021. Keywords used includes ‘COVID-19’, ‘pregnant women’, ‘maternal outcome’ and ‘fetal outcome.’ Critical appraisal and selection were conducted to identify articles that fulfill inclusion criteria. The selected articles were analyzed thematically to answer the research questions.Results: Literature search yielded 124 articles with 11 included in final analysis. The results showed low to moderate risk of maternal and perinatal adverse outcomes, including low risks for maternal and perinatal mortality coupled with moderate risk for maternal ICU admission and preterm birth with NICU admission for the newborn. Higher risk was observed for pregnant women with symptomatic COVID-19 infection, which points to the necessity for awareness of the risk and targeted early detection efforts.Conclusion: There are low risk for adverse maternal and perinatal outcomes, including mortality and ICU/NICU admission, associated with COVID-19 infection in pregnant women. Risk factors for adverse outcomes included pregnant women with symptomatic COVID-19 infection.Keywords: COVID-19, ICU, maternal mortality, NICU, perinatal mortality, preterm birth Abstrak Tujuan: Mendeskripsikan dan mengidentifikasi faktor risiko luaran maternal dan perinatal COVID-19 pada ibu hamil.Metode: Penelusuran literatur dilakukan di database MEDLINE dan Google Scholar untuk artikel yang diterbitkan pada Desember 2020 hingga Januari 2021. Kata kunci yang digunakan meliputi 'COVID-19', 'wanita hamil', 'keluaran ibu' dan 'hasil janin'. Penilaian dan seleksi kritis dilakukan untuk mengidentifikasi artikel yang memenuhi kriteria inklusi. Artikel yang dipilih dianalisis secara tematis untuk menjawab pertanyaan penelitian.Hasil: Penelusuran literatur menghasilkan 124 artikel dengan 11 termasuk dalam analisis akhir. Hasil penelitian menunjukkan risiko rendah hingga sedang untuk luaran buruk maternal dan perinatal, termasuk risiko rendah untuk kematian maternal dan perinatal ditambah dengan risiko sedang untuk masuk ICU ibu dan kelahiran prematur dengan masuk NICU untuk bayi baru lahir. Risiko yang lebih tinggi diamati untuk wanita hamil dengan infeksi COVID-19 bergejala, yang menunjukkan perlunya kesadaran akan risiko dan upaya deteksi dini yang ditargetkan.Kesimpulan: Terdapat risiko rendah untuk laran buruk maternal dan perinatal, termasuk kematian dan rawat inap di ICU/NICU, terkait dengan infeksi COVID-19 pada wanita hamil. Faktor risiko untuk luaran buruk adalah wanita hamil dengan gejala infeksi COVID-19.Kata kunci: COVID-19, ICU, kelahiran preterm, mortalitas maternal, mortalitas perinatal, NICU
Rectovaginal Fistulae in Post Repair Chronic Perineal Rupture: Fistula Rektovagina pada Pascarepair Ruptur Total Perienum Lama Budi I. Santoso; Shirley A. Tunggadewi; Yulia M. Sari
Indonesian Journal of Obstetrics and Gynecology Volume 9 No. 4 October 2021
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v9i4.1562

Abstract

Objective: To report and discuss the causes and management of rectovaginal fistula in post repair chronic total perineal rupture.Method: A case report, a 29-year-old female patient who came to Fatmawati General Hospital with complaints of anal incontinence 9 days after repair chronic total perineal rupture. Rectovaginal examination revealed a rectovaginal fistula 2 mm in diameter at 1.5 cm proximal to the hymenal ring.Discussion: Rectovaginal fistula is one of the complications after repair of hronic total perineal rupture which disturbs the quality of life of women. The patient was diagnosed with a rectovaginal fistula in post repair chronic total perineal rupture. Conservative management with wound care and administration of honey to the patient showed improved postoperative outcome.Conclusion: Anatomical identification of the anal sphincter complex, surgical technique and postoperative care are important in preventing complications following repair of chronic total perineal rupture repair.Keywords : obstetrics sphincter anal injury, postrepair chronic, rectovaginal fistulae . Abstrak Tujuan : Untuk melaporkan dan mendiskusikan penyebab dan tatalaksana kasus fistula rektovagina pasca repair ruptur perineum total lama.Metode: Sebuah laporan kasus, pasien perempuan 29 tahun yang datang ke RSUP Fatmawati dengan keluhan inkontinensia anal 9 hari pascarepair ruptur perineum total lama. Pemeriksaan rectovaginal menunjukkan fistula rektovagina diameter 2 mm pada 1,5 cm proksimal hymenal ring.Diskusi : Fistula rektovagina merupakan salah satu komplikasi pascarepair ruptur perineum total yang mengganggu kualitas hidup perempuan. Pasien didiagnsos fistula rektovagina pascarepair ruptur perineum total lama. Manajemen konservatif dengan perawatan luka dan pemberian madu pada pasien menunjukkan perbaikan luaran paska operasi.Kesimpulan: Identifikasi anatomis kompleks sfingter ani, teknik operasi dan perawatan pascaoperasi penting dalam mencegah komplikasi pascarepair ruptur perineum total lama.Kata kunci: cedera sfingter ani obstetri, fistula rectovagina, repair ruptur perineum total lama
Profile of Pregnant Women who Underwent Cesarean Section and their Perinatal Outcome at a Tertiary Referral Hospital: Profil Ibu Hamil dengan Indikasi Operasi Caesar dan Luaran Perinatal di Rumah Sakit Rujukan Tersier Junita Indarti; Sigit Purbadi; Ajeng Larasati; Hesti N. Rizqi; Kristian Alda; Adithya Weladatika; Leonita T. A. Sutrisna; Muhammad Azmi; Caesar Nurfiansyah
Indonesian Journal of Obstetrics and Gynecology Volume 9 No. 4 October 2021
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v9i4.1608

Abstract

Abstract Objective: To investigate the effectiveness of referral system, in regard to pregnant women with indication of C-section, and to learn the patients’ profile and their baby’s perinatal outcome.Methods: The research uses a retrospective descriptive method utilizing patient medical records with history of C-section at RSCM from January 2016 to December 2019. The target population is all pregnant women who were referred and performed cesarean section to at the hospital.Results: The most indications of C-section were premature membrane ruptures (16.1%), fetal distress (14.5%) and previous C-section (14.1%). There were 1585 cases (41.9%) coming without referral, 779 cases (20.6%) were bookcase, and 806 (21.3%) non-bookcase without referral. The main reasons for referral were absence of NICU facilities (27.31%), premature membranes rupture (20.81%), and eclampsia/preeclampsia/HELLP syndrome (15.40%). Most babies are born with normal weight (2500-3999 grams) as many as 45.1% and 54.9% are groups of babies with abnormal weight. Most babies have an APGAR score 5 minute of 7-10 (83.6%). As many as 47.8% rooming in and infants requiring perinatological care in both SCN and NICU are 52.1%.Conclusion: The study found that the effectiveness of RSCM tiered referral system still has much room for improvements. The study also found gap between number of referred cases and the cases eventually underwent for C-section with the same indication. The screening can be done better for an indication of the origin of the reference whether it is appropriate to do the reference or not.Keywords: caesarean section, perinatal outcome, pregnant women, referral system. Abstrak Tujuan: Untuk mengetahui efektivitas sistem rujukan pada ibu hamil dengan indikasi seksio sesarea, serta mengetahui profil pasien dan hasil perinatal bayinya.Metode: Studi ini menggunakan metode deskriptif retrospektif dengan memanfaatkan rekam medis pasien riwayat seksio sesarea di RSCM dari Januari 2016 sampai Desember 2019. Populasi sasaran adalah semua ibu hamil yang dirujuk dan dilakukan seksio sesarea di RSCM.Hasil: Indikasi seksio sesarea terbanyak adalah ketuban pecah dini (16,1%), gawat janin (14,5%), dan riwayat seksio sesarea sebelumnya (14,1%). Ada 1.585 kasus (41,9%) yang datang tanpa rujukan, 779 (20,6%) bookcase, dan 806 (21,3%) non-bookcase tanpa rujukan. Alasan utama rujukan adalah tidak adanya fasilitas NICU (27,31%), ketuban pecah dini (20,81%), dan eklampsia/preeklamsia/sindrom HELLP (15,40%). Sebagian besar bayi lahir dengan berat badan normal (2500-3999 gram) sebanyak 45,1% dan 54,9% merupakan kelompok bayi dengan berat badan tidak normal. Sebagian besar bayi memiliki skor APGAR 5 menit 7-10 (83,6%). Sebanyak 47,8% rawat inap dan bayi yang membutuhkan perawatan perinatologi baik di SCN maupun NICU sebanyak 52,1%. Kesimpulan: Studi ini menemukan bahwa efektivitas sistem rujukan berjenjang RSCM masih memiliki banyak ruang untuk perbaikan. Studi ini juga menemukan kesenjangan antara jumlah kasus yang dirujuk dan kasus yang akhirnya menjalani seksio sesarea dengan indikasi yang sama. Penapisan dapat dilakukan lebih baik untuk indikasi asal rujukan apakah layak dilakukan rujukan atau tidak.Kata kunci: ibu hamil, luaran perinatal, seksio sesarea, sistem rujukan
Obstetrics Service Post COVID-19 Noroyono Wibowo
Indonesian Journal of Obstetrics and Gynecology Volume 9 No. 4 October 2021
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v9i4.1660

Abstract

Long-term Outcome of Severe Preeclampsia Cases: Cross – Sectional Study: Keluaran Jangka Panjang Kasus Preeklamsia Berat: Studi Potong Lintang Yuditiya Purwosunu; Nurida M. Siagian
Indonesian Journal of Obstetrics and Gynecology Volume 10 No. 1 January 2022
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v10i1.637

Abstract

Objectives: To investigate the long term outcome of severe preeclampsia mother by clinically and laboratory, and the long term outcome of the baby that she delivered. Method: This is a cross sectional study was conducted at Obstetrics Outpatient Clinic Dr. Cipto Mangunkusumo General Hospital (Cipto Mangunkusumo NCGH) on January–June 2017, of patients with previous severe preeclampsia that gave birth in Cipto Mangunkusumo NCGHon January 2014 – December 2016, and was descriptively analyze using SPSS Statistics 24. Results: One hundred and twenty seven patients were studied, divided into 3 groups of post – delivery time which were 6 months, 12 months, and 24 months. The 6 months’ group, mean of blood pressure were 147/92 mmHg (SD 38/SD 39), BMI 29 kg/m2 (SD 6), CRP level 16.6 mg/l (0.3 – 42.60) and urine protein dipstick 1 (0 – 3). The 12 months’ group, mean of blood pressure were 112/88 mmHg (SD 12/SD 24), BMI 21s kg/m2 (SD 7), CRP level 12.7 mg/l (3.4 – 15.2) and urine protein dipstick 0 (0 – 3). The 24 months’ group, mean blood pressure 154/95 mmHg (SD 45/SD 62), BMI 28.83 kg/m2, CRP level 14,2 mg/l (SD 8.54) and urine protein dipstick 0 (0 – 3). Meanwhile, the long – term outcome of babies that 68% baby were born with preterm condition and mean birth weight were 1943 grams (SD 1245), the 5th minute Apgar score >7 were 63.78%, and only 44.88% baby had normal growth development. Conclusion: The long – term outcome patients with previous severe preeclampsia are blood pressure, BMI, and CRP level still high, and negative urine protein level until 2 years of post – delivery. The long – term outcome of the babies that delivered were on preterm condition and low birth weight, with less than 50% had normal growth and development. Keywords: c–reactive protein, growth and development, proteinuria, post–delivery, severe preeclampsia. Abstrak Tujuan: Untuk mengetahui keluaran jangka panjang pada pasien ibu PEB dari sudut klinis dan laboratoris, serta keluaran jangka panjang bayi yang dilahirkan. Metode: Penelitian ini menggunakan desain potong lintang terhadap pasien riwayat PEB yang pernah melahirkan di RSUPN Dr. Cipto Mangunkusumo pada bulan Januari 2014–Desember 2016. Subjek diminta datang ke Poli Obstetri RSUPN Dr. Cipto Mangunkusumo pada Januari–Juni 2017 untuk dilakukan pemeriksaan klinis dan laboratoris (CRP dan protein urin), serta dilakukan analisa deskriptif menggunakan SPSS Statistik 24. Hasil: Sebanyak 127 pasien yang diteliti terbagi dalam 3 kelompok yaitu pasien riwayat PEB pasca persalinan 6 bulan (kelompok I), 12 bulan (kelompok II), dan 24 bulan (kelompok III). Kelompok I didapatkan rerata tekanan darah (TD) 147/92 mmHg (SD 38/SD 39), IMT 29 kg/m2 (SD 6), kadar CRP 16,6 mg/l (0,3 – 42,60) dan protein urin 1 (0 – 3). Kelompok II didapatkan rerata tekanan darah (TD) 112/88 mmHg (SD 12/SD 24), IMT 21 kg/m2 (SD 7), kadar CRP 12,7 mg/l (3,4 – 15,2) dan protein urin 0 (0 – 3). Kelompok III rerata TD 154/95 mmHg (SD 45/SD 62), IMT 28,83 kg/m2, dengan rerata kadar CRP 14,2 mg/l (SD 8,54) dan protein urin 0 (0 – 3). Sedangkan keluaran jangka panjang bayi yang dilahirkan bahwa 68% lahir dengan kondisi preterm dengan rerata berat lahir 1.943 gram (SD 1.245), nilai Apgar menit ke-5 >7 63,78%, dan hanya 44,88% tumbuh – kembang bayi normal. Kesimpulan: Gambaran keluaran jangka panjang pasien riwayat PEB didapatkan tekanan darah, IMT dan kadar CRP masih tinggi, serta protein urin urin negatif setelah 2 tahun pascapersalinan. Keluaran jangka panjang bayi yang dilahirkan mayoritas kondisi preterm dan berat lahir rendah, dengan kurang dari 50% bayi tumbuh – kembang normal. Kata kunci: c– reactive protein, preeklamsia berat, proteinuria, pascapersalinan, tumbuh kembang bayi.
Multiple Congenital Anomalies: Meningoencephalocele, Labiopalatoschisis and Clubfoot with Normal Chromosomal Analysis : Multipel Kongenital Anomali : Meningoensefalokel, Labiopalatoskhizis, dan Kaki Pengkor dengan Hasil Analisis Kromosom Normal Sefty M. Samosir; Angghea Rachmiawaty; Ita Fatati; Alamsyah Aziz
Indonesian Journal of Obstetrics and Gynecology Volume 10 No. 1 January 2022
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v10i1.1366

Abstract

Objective : To perform chromosomal microarray when similar case was found.Methods: Case reportCase : G1P0A0, 20 years-old, 23-24 weeks gestation, normal BMI, was diagnosed by ultrasonography with multiple congenital anomaly consisted by meningoencephalocele, labiopalatoschisis, and clubfoot. Amniocentesis was performed to manage karyotyping analysis and a result of 46 XY was obtained. Neonate was delivered with exact condition according to prenatal diagnosis and was demised 6 hours postnatal. Patient had no history of smoking or DM, and no familial congenital deformity. Patient was a worker in textile manufactory and inadequacy folic acid intake during pregnancy was known.Early suspicion of aneuploidy as cause of multiple congenital anomalies in this case was not proven otherwise. Serology test also found no congenital infection. Literature research indicated tendency of MTHFR polymorphisms. Genetic analysis such as chromosomal microarray to establish involvement of MTHFR polymorphism is needed.Conclusion : This case should behold as clinicians’ consideration to perform additional examination and patients counseling when similar anomaly was found during prenatal ultrasonography examination.Keyword : chromosomal microarray,karyotyping; MTHFR polymorphism, mutiple congenital anomaly. Abstrak Tujuan : Untuk melakukan pemeriksaan chromosomal microarray pada kasus yang sama.Metode: Laporan kasus.Kasus : G1P0A0, usia 20 tahun, hamil 23-24 minggu, didiagnosis secara ultrasonografi dengan kelainan kongenital multipel berupa meningoensefalokel, celah bibir-palatum, dan club foot. Amniosentesis dilakukan pada pasien untuk analisis kromosom dan didapatkan hasil 46 XY. Bayi lahir dengan kondisi yang sama dengan diagnosis prenatal tersebut dan meninggal 6 jam pasca salin. Dari hasil anamnesis dan pemeriksaan kami dapatkan pasien bukan perokok, tidak ada keluarga dengan cacat bawaan, indeks masa tubuh pasien normal. Pasien merupakan karyawan pabrik tekstil dan pasien tidak mengkonsumsi asam folat adekuat selama kehamilan. Dua data terakhir yang kemungkinan berkontribusi terjadinya kelainan kongenital multipel pada kasus ini, yaitu kontak dengan teratogen dan defisiensi asam folat. Dugaan awal kelainan kromosom sebagai penyebab kelainan kongenital multipel pada kasus ini tidak terbukti. Sayangnya, investigasi-investigasi lebih lanjut berupa analisis genetik, seperti pemeriksaan apakah terdapat polimorfisme MTHFR yang berhubungan dengan defisiensi asam folat pada kasus ini tidak dilakukan karena keluarga pasien menolak. Kesimpulan : Kasus ini sebaiknya menjadi bahan pertimbangan klinisi untuk melakukan pemeriksaan tambahan dan edukasi ke pasien pada saat menemukan kelainan yang sama pada pemeriksaan ultrasonografi prenatal.Keyword: chromosomal microarray; karyotyping; multipel kongenital anomali; polimorfisme MTHFR
Increased Knowledge and Attitudes of Preconception Care using the Dedi Torri Application: Peningkatan Pengetahuan dan Sikap Perawatan Prakonsepsi melalui Aplikasi Dedi Torri Ni nyoman Y. Abriyani; Tri Sunarsih; Luluk Rosida
Indonesian Journal of Obstetrics and Gynecology Volume 10 No. 1 January 2022
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v10i1.1453

Abstract

Objetive: To determine the increase in knowledge and attitude of preconception care through the application of DeDitorRi.Methods: Uses pre-experiment using a one group pre-test and post-test design.Result: Based on the paired t test in the first health education using the DeDi torRi application to the difference in knowledge obtained with a p value of 0.000 in attitudes with a p value of 0.000. Based on paired t test in the second health education using the DeDitorRi application to the difference of knowledge obtained with a p value of 0.000 and an attitude with a p value of 0.000.Conclusion: Preconception care health education through DeDi torRi (application-based module) and education that is given repeatedly to reproductive age mothers can influence the increase in knowledge and attitude of preconception care.Keywords: health education applications, preconception care, women of reproductive. Abstrak Tujuan : Untuk mengetahui peningkatan pengetahuan dan sikap perawatan prakonsepsi melalui aplikasi DeDi torRi. Metode : Pre-eksperimen dengan menggunakan rancangan one group pre-test dan post-test.Hasil: Berdasarkan uji paired t test pada pendidikan kesehatan pertama menggunakan aplikasi DeDi torRi terhadap beda pengetahuan yang didapatkan dengan p value sebesar 0,000 pada sikap dengan p value 0,000. Berdasarkan uji paired t test pada pendidikan kesehatan kedua menggunakan aplikasi DeDi torRi terhadap beda pengetahuan yang didapatkan dengan p value sebesar 0,000 dan pada sikap dengan p value 0,000.Kesimpulan: Pendidikan kesehatan menggunakan aplikasi DeDi torRi (aplikasi berbasis modul) efektif dalam meningkatkan pengetahuan dan sikap pada perempuan usia reproduktif terhadap perawatan prakonsepsi. Kata kunci: aplikasi pendidikan kesehatan, perawatan prakonsepsi, perempuan usia reproduktif.

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