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INDONESIA
Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia)
Published by Perkumpulan Obstetri dan Ginekologi Indonesia
ISSN : 23386401     EISSN : 23387335     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology Public Health
The Indonesian Journal of Obstetrics and Gynecology is an official publication of the Indonesian Society of Obstetrics and Gynekology. INAJOG is published quarterly.
Arjuna Subject : -
Articles 1,731 Documents
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The Pruritic Urticarial Papules and Plaques of Pregnancy (PUPPP): Papula Urtikaria Pruritik dan Plak pada Kehamilan (PUPPP) Riyan H. Kurniawan; Ugi U. Dimas; Afria Arista
Indonesian Journal of Obstetrics and Gynecology Volume 10 No. 1 January 2022
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v10i1.1521

Abstract

Objective: To report a rare case of pruritic urticarial papules and plaques of pregnancy (PUPPP) in multiparous woman and its literature review.Methods: A case report with literature review.Discussion: This article reports a multigravida woman, presented with aterm pregnancy with sign and symptoms of pruritic urticarial papules and plaques since the first trimester of pregnancy. This case supports the morphological variation of skin lesions in PUPPP, as the patient had lesions other than the characteristic urticarial papules and plaques, with hyperpigmentation skin changes. The management of this case include oral and topical corticosteroids, oral antihistamines and moisturizer is used to relieve pruritus and skin lesions.Conclusion: PUPPP should be included in the differential diagnosis to differentiate this entity from other dermatoses associated with pregnancy, in order to provide appropriate treatment and reassurance.Keywords: papules, plaques, pregnancy, pruritic, urticarial. Abstrak Tujuan: Untuk melaporkan kasus langka mengenai papula urtikaria pruritik dan plak pada kehamilan (PUPPP) perempuan multipara, membahas literatur terkait pada PUPPP.Metode: Laporan kasus dengan telaah literatur.Diskusi : melaporkan kasus perempuan multigravida, datang dalam usia kehamilan cukup bulan dengan tanda dan gejala papula, plak, urtikaria dan pruritus sejak trimester pertama kehamilan. Kasus ini mendukung variasi morfologi lesi kulit pada PUPPP, karena pasien memiliki lesi selain papula dan plak urtikaria yang khas, dengan perubahan kulit hiperpigmentasi. Penatalaksanaan kasus ini meliputi kortikosteroid oral dan topikal, antihistamin oral dan pelembab yang digunakan untuk meredakan pruritus dan lesi kulit.Kesimpulan: PUPPP perlu dimasukkan dalam diagnosis banding untuk membedakan entitas ini dari penyakit kulit lain yang terkait dengan kehamilan, untuk memberikan pengobatan dan pelayanan yang tepat.Kata kunci: kehamilan, , papula, plak, pruritus, urtikaria
Influence of Total Hysterectomy to Sexual Function: Pengaruh Histerektomi Total dengan Fungsi Seksual Andini Z. Dini; Ferry Yusrizal; Firmansyah Basir; Theodorus
Indonesian Journal of Obstetrics and Gynecology Volume 10 No. 1 January 2022
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v10i1.1524

Abstract

Objective: To determine whether there are differences the impact of total hysterectomy on sexual function between each woman. Women who perform total hysterectomy often experience fear of the negative effects of hysterectomy on their sexual function.Methods: Randomized clinical trials have been conducted in outpatient clinic Obstetrics and Gynecological wards of Dr. Muhammad Hoesin General Hospital, Palembang from February to October 2020. There were 40 samples of women undergoing a total hysterectomy met the inclusion criteria. Sexual function before and after hysterectomy was analyzed with the Wilcoxon test. Data analysis using SPSS version 22.0.Results: This study showed decreased of desire, decreased stimuli, decreased orgasm, increased lubrication, increased sexual satisfaction, and increased dyspareunia samples after a total hysterectomy. However, with statistical analysis obtained results there were no meaningful changes in sexual function of desire (p = 0.849), stimuli (p = 0.716), lubrication (p = 0.261), orgasm (p = 0.839), sexual satisfaction (p = 0.613) and dyspareunia (p = 0.510) after total hysterectomy .Conclusion: It can be concluded that there is no significantly total hysterectomy effect on sexual function, based on FSFI (sexual desire, sexual arousal, lubrication, orgasm, sexual satisfaction, and pain.Keywords: clinical trial, FSFI, hysterectomy, sexual function. Abstrak Tujuan: Mengetahui adakah perbedaan dampak histerektomi total pada fungsi seksual antara setiap perempuan. Perempuan yang melakukan histerektomi total sering mengalami ketakutan akan efek negatif histerektomi pada fungsi seksualnya. Metode: Telah dilakukan uji klinis secara acak di poliklinik rawat jalan bangsal Obstetri dan Ginekologi RSUP Dr. Muhammad Hoesin Palembang dari bulan Februari sampai Oktober 2020. Sebanyak 40 sampel perempuan yang menjalani histerektomi total memenuhi kriteria inklusi. Fungsi seksual sebelum dan sesudah histerektomi dianalisis dengan uji Wilcoxon. Analisi data menggunakan SPSS versi 22.0.Hasil: Penelitian ini menunjukkan penurunan hasrat, penurunan rangsangan, penurunan orgasme, peningkatan lubrikasi, peningkatan kepuasan seksual, dan peningkatan dispareunia setelah histerektomi total. Namun dengan analistik statistik didapatkan hasil tidak ada perubahan yang bermakna pada fungsi seksual yaitu hasrat (p=0,849), rangsangan (p=0,716), lubrikasi (p= 0,716), lubrikasi (p=0,261), orgasme (p=0,839), kepuasan seksual (p= 0,613), dan dispareunia (p= 0,510) setelah histerektomi total.Kesimpulan: Dapat disimpulkan bahwa tidak ada pengaruh histerektomi total yang signifikan terhadap fungsi seksual berdasarkan FSFI (hasrat, seksual, gairah seksual, lubrikasi, orgasme, kepuasan seksual, dan nyeri.Kata kunci: fungsi seksual, FSFI, histerektomi, uji klinis.
Fetomaternal Outcome of Aterm Labor with Pregnant Thrombocytopenia: Luaran Fetomaternal pada Ibu Hamil Aterm dengan Trombositopenia Rajuddin Rajuddin; Muhammad Iqbal; Cut M. Yeni
Indonesian Journal of Obstetrics and Gynecology Volume 10 No. 1 January 2022
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v10i1.1526

Abstract

Objective : To determine the relationship between term pregnant women and the incidence of post-partum haemorrhage, duration of healing of incision/perineorhaphy wounds, fetal thrombocytopenia, APGAR value and birth weight of infants in dr. Zainal Abidin Hospital Banda Aceh.Methods: Design of research is observational analytic with a cross sectional approach. The research sample was taken by the total sampling method. The population in this study were all pregnant patients at term who came to the dr. Zainoel Abidin Hospital Banda Aceh and experienced thrombocytopenia at a predetermined time, met the inclusion and exclusion criteria. Analysis data with the Pearson correlation test formula to assess the strength of the relationship between two variables.Results: The prevalence of aterm pregnant women with thrombocytopenia who visited and gave birth at Dr. Zainoel Abidin General Hospital during the study period was 1.62% from 1850 visited pregnant women. A total of 30 samples in this study, obtained a maternal outcome were postpartum haemorrhage as much as 60% (p-value 0.000). The duration of wound healing was 26.70%, (p-value 0.008). While the fetal outcomes were the incidence of neonatal thrombocytopenia 50% (p-value 0,000), nenonatal asphyxia with an APGAR value of 4-6 as much as 43.30% (p-value 0.003) and low birth weight of the baby at 36.70% (p-value 0.033). The five variables obtained a positive correlation with varying strengths of the relationship.Conclusion: There is a close relationship between the incidence of thrombocytopenia at term pregnant women at delivery and fetomaternal outcomes in dr. Zainoel Abidin Hospital Banda AcehKeywords: fetal outcome, maternal outcome, Score APGAR, thrombocytopenia. Abstrak Tujuan : Untuk mengetahui hubungan ibu hamil aterm dengan kejadian perdarahan post-partum, lamanya penyembuhan luka insisi/perineorafi, trombositopenia janin, nilai APGAR dan berat badan lahir bayi di Rumah Sakit Umum dr. Zainal Abidin Banda Aceh. Metode: Jenis penelitian ini adalah analitik observasional dengan pendekatan cross sectional. Sampel penelitian diambil dengan metode total Sampling. Populasi pada penelitian ini adalah semua pasien hamil aterm yang datang ke RSUD dr. Zainoel Abidin Banda Aceh dan mengalami trombositopenia pada rentang waktu yang telah ditentukan, memenuhi kriteria inklusi dan eksklusi. Analisa data dengan melakukan uji korelasi Pearson untuk menilai kekuatan hubungan dua variabel.Hasil: Prevalensi ibu hamil aterm dengan trombositopenia pada penelitian adalah 1,62% dari 1850 ibu hamil yang berkunjung. Sebanyak 30 sampel pada penelitian didapatkan luaran maternal yaitu perdarahan postpartum sebanyak 60% (p-value 0,000). Lama penyembuhan luka didapatkan26,70%, (p-value 0,008). Sedangkan luaran fetal yaitu kejadian trombositopenia neonatus 50% (p-value 0,000), asifiksia nenonatus dengan nilai APGAR 4-6 sebanyak 43,30% (p-value 0,003) dan berat badan bayi lahir rendah 36,70% (p-value 0,033). Kelima variabel didapatkan korelasi positif dengan kekuatan hubungan yang bervariasi.Kesimpulan: Terdapat hubungan erat antara kejadian trombositopenia ibu hamil aterm saat persalinan terhadap luaran fetomaternal di RSUD dr. Zainoel Abidin Banda Aceh.Kata kunci : luaran fetal, luaran maternal, nilai APGAR, trombositopenia.
Return of Fertility After Discontinuation of Contraception According Type of Contraception, Duration of Use, Age and BMI: Kembalinya Kesuburan Pasca Penghentian Alat Kontrasepsi Berdasarkan Jenis Kontrasepsi, Lama Pemakaian, Usia dan IMT Quinita M. J. Noronha; Hafi Nurinasari; Uki R. Budihastuti; Darto
Indonesian Journal of Obstetrics and Gynecology Volume 10 No. 1 January 2022
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v10i1.1527

Abstract

Objective : To determine the relationship between the type of contraception, duration of use, BMI, and age on the return of fertility.Methods : This was an analytic observational study with a cross-sectional design. The subjects in this study was 123 multigravida mothers who had met the inclusion criteria, namely with a history of regular intercourse and the exclusion criteria in this study were multigravida mothers with a history of abortion and failure of the family planning method. Data were collected by direct interviews and medical record data. Data were analyzed using Chi-square test and Logistic Regression test.Results: The results of the Chi-square analysis showed a relationship between the type of contraception (p=0.001;OR=1.29) and age (p=0.031;OR=4.69) with the return of fertility. However, there was no correlation between the duration of use (p=0.964;OR=0.97) and BMI (p=0.246;OR=0.50) with the return of fertility. In the logistic regression test, there was no partial effect of the type of contraception (p=0.997;OR=0.22) and age (p=0.058;OR=0.01).Conclusion : Based on the results of the analysis, it can be concluded that there is a relationship between the type of contraception and age with the return of fertility after family planning, where non-hormonal contraceptives and <30 years of age return to fertility faster, namely <1 year, but there is no relationship between duration of use and BMI with the return of fertility after family planning.Keywords: contraception, family planning, fertility. Abstrak Tujuan: Mengetahui hubungan jenis kontrasepsi, lama pemakaian, IMT, dan usia terhadap kembalinya kesuburan.Metode: Penelitian ini merupakan penelitian observasional analitik dengan desain potong lintang. Subjek penelitian ini adalah ibu multigravida yang telah memenuhi kriteria inklusi yaitu dengan riwayat senggama teratur dan bersedia menjadi responden serta kriteria ekslusi dalam penelitian ini adalah ibu multigravida dengan riwayat abortus dan kegagalan metode KB. Besar subjek dalam penelitian ini sebanyak 123 orang. Pengambilan data dilakukan dengan wawancara langsung dan melihat data rekam medis. Analisis data dilakukan uji statistik Chi-square dan uji Regresi Logistik.Hasil : Hasil analisis dengan Chi-square, menunjukan adanya hubungan jenis kontrasepsi (p = 0,001; OR = 1,29) dan usia (p=0,031; OR = 4,69) dengan kembalinya kesuburan. Namun, tidak terdapat hubungan lama pemakaian (p= 0,964; OR =0,97) dan IMT (p= 0,246; OR =0,50) dengan kembalinya kesuburan. Pada uji regresi logistik tidak terdapat pengaruh parsial dari jenis kontrasepsi (p=0,997; OR =0,22) dan usia (p=0,058; OR=0,01).Kesimpulan : Berdasarkan hasil analisis yang dilakukan dapat disimpulkan terdapat hubungan jenis kontrasepsi dan usia dengan kembalinya kesuburan pasca KB, dimana pada jenis kontrasepsi non hormonal dan usia < 30 tahun lebih cepat kembali subur yaitu < 1 tahun, namun tidak terdapat hubungan lama pemakaian dan dengan kembalinya kesuburan pasca KB.Kata kunci: keluarga berencana, kesuburan kontrasepsi.
Nifedipine, Calcium Channel Blocker (Antihypertensive), as a Tocolytic to inhibit Premature Birth in Reducing the Risk of Neonatal Death in Childbirth: Meta-Analysis and Systematic Review of Large Clinical Trial: Nifedipine, Penghambat Kanal Kalsium (Antihipertensi), sebagai Tokolitik dalam Menghambat Kelahiran Prematur dalam Menurunkan Risiko Kematian Neonatus Pada Persalinan: Meta-Analisis dan Telaah Sistematis dari Studi Besar Uji Klinis Axel J. Olda; Joue Abraham Trixie; Glenn Bolang; Yoga Rahmat Witular; Saerang Langi
Indonesian Journal of Obstetrics and Gynecology Volume 10 No. 1 January 2022
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v10i1.1549

Abstract

Objective: To evaluate the role of nifedipine as a tocolytic agent.Methods: Literature searches use medical search engines for example Pubmed, Google Scholar and Medical scientific journals, as like the American kind of Journal that is Learning Obstetrics and also learn about Gynecology. The literature used were published from 1986 to 2020. The main data extraction was in the form of an extended gestation period, divided into 48 hours, 7 days, and 37 weeks with data analysis using the RevMan 5.4 application. Result: Twenty-four clinical trials were analyzed with total amount shown of 2,889 study subjects. The purpose of using kind of nifedipine to be such a tocolytic indicates no significant difference, within 48 hours or (RR 1.06; 95% CI, 0.99 - 1.13; p shown = 0.12), 7 days (RR 1.02; 95% CI, 0.95 - 1.09; p = 0.57), and up to 37 weeks (RR 1.22; 95% then CI, 0.96 - 1.54; p = 0.10) at the time it is compared with the group of control.Conclusion: Administration of nifedipine as a tocolytic did not have a statistically significant difference, both in prolonging pregnancy and side effects for pregnant women and neonates compared to the control group.Keyword: meta-analysis, nifedipine, preterm delivery, prolongation pregnancy, tocolytic. Abstrak Tujuan: Untuk mengevaluasi peran nifedipin sebagai tokolitik.Metode: Pencarian literatur menggunakan mesin pencari medis seperti Pubmed, Google Scholar dan jurnal ilmiah medis, seperti American Journal of Obstetrics and Gynecology. Literatur yang digunakan dalam rentang tahun 1986 - 2020. Kata kunci adalah ("pregnant woman" OR pregnancy) AND ("preterm birth" OR "preterm labor") AND nifedipine. Ekstraksi data utama berupa perpanjangan masa kehamilan, dibagi menjadi 48 jam, 7 hari, dan 37 minggu dengan analisis data menggunakan aplikasi RevMan 5.4Hasil: Dua puluh empat uji klinis yang dianalisa dengan total 2,889 subjek penelitian. Penggunaan nifedipine sebagai tokolitik menunjukkan tidak ada sesuatu yang berbeda secara signifikan, dalam 48 jam (RR 1.06; 95% then CI, 0.99 - 1.13; p results = 0.12), 7 hari (RR shown 1.02; 95% then CI, 0.95 - 1.09; p = 0.57), dan sampai 37 minggu (RR 1.22; 95% CI, 0.96 - 1.54; p shown = 0.10) apabila dibandingkan dengan kelompok kontrol. Begitu pun dengan efek samping pada ibu hamil (RR 0.99; 95% CI, 0.74 - 1.31; p = 0.92) dan neonatus (RR 0.93; 95% of CI, 0.83 - 1.04; p shown = 0.21), ditemukan adanya kesamaan yang serupa pada grup atau golongan dalam kendali.Kesimpulan: Pemberian nifedipine sebagai tokolitik tidak memiliki perbedaan yang signifikan secara statistik, baik dalam memperpanjang masa kehamilan maupun efek samping kepada ibu hamil dan neonatus dibandingkan dengan kelompok kontrol.Kata kunci: kelahiran prematur, meta-analysis, nifedipin, prolongation pregnancy, tokolitik
Risk of Malignancy Index 3 (RMI3) Performance as a Predictor Advanced Stage Epithelial Ovarian Carcinoma used for NACT: Perfoma Risk of Malignancy Index 3 (RMI3) sebagai Prediktor Karsinoma Ovarium Epithelial Stadium Lanjut untuk Pertimbangan Pemberian NACT Tatit Nurseta; Putu A. Herliawati; Dhian E. P. Harnandari; Kusworini Handono; Yahya Irwanto; Sutrisno Sutrisno
Indonesian Journal of Obstetrics and Gynecology Volume 10 No. 1 January 2022
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v10i1.1599

Abstract

Effect of Early versus Delayed Cord Clamping on Hematological Parameters of Term Neonates: Pengaruh Penjepitan Tali Pusat Dini Dibandingkan dengan Tertunda pada Parameter Hematologi Neonatus Aterm Chaithra Ravishankar; Ratan Kumar Das; Chandra Bhanu Dalal; Tapan Pattanaik
Indonesian Journal of Obstetrics and Gynecology Volume 10 No. 1 January 2022
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v10i1.1618

Abstract

Objectives : To compare the serum bilirubin, hemoglobin, and hematocrit in term infants undergoing delayed cord clamping with early cord clamping after normal and caesarean delivery.Methods : This is a prospective observational study. The neonates in which cord clamping was done within 15 seconds were considered in early cord clamping (ECC) group and where cord clamping was done after 1 minute was considered in delayed cord clamping (DCC) group. The PCV, Hb, serum bilirubin were observed after 48 hours in both the groups and compared.Results : There was statistically significant difference in means of Hb level (p = 0.001) and PCV level (p = 0.001) between DCC and ECC group whereas no statistically significant difference was present in total serum bilirubin level (p = 0.359).Conclusion: There was no significant increase in risk of polycythaemia and hyperbilirubinemia between delayed cord clamping and early cord clamping group rather has beneficial effects in increasing the haemoglobin and haematocrit in the infants.Keywords : delayed cord clamping, early cord clamping, hematocrit, hemoglobin, serum bilirubin, hyperbilirubinemia. Abstrak Tujuan: Untuk membandingkan bilirubin serum, hemoglobin, dan hematoklit pada bayi aterm yang dilakukan delayed cord clamping dan early cord clamping setelah persalinan normal dan seksio sesarea.Metode: Studi ini merupakan studi prospektif. Neonatus yang dilakukan cord clamping dalam 15 detik dikelompokkan pada delayed cord clamping (DCC). PCV, Hb, bilirubin serum diobservasi dalam 48 jam pada kedua kelompok, kemudian dibandingkan.Hasil: Terdapat perbedaan signifikan antara kadar Hb (p = 0,001) dan PCV (p = 0,0010 antara kelompok DCC dan ECC, sedangkan tidak terdapat perbedaan signifikan pada kadar bilirubin serum total (p = 0,3590Kesimpulan: Tidak terdapat peningkatan signifikan polisitemia dan hyperbilirubinemia antara DCC dan ECC.Kata kunci: delayed cord clamping, early cord clapming, hematokrit, hemoglobin, serum bilirubin, hyperbilirubinemia
Vaginal and Perineal Rejuvenation: Understanding Aesthetic Gynecology Sonny Sasotya
Indonesian Journal of Obstetrics and Gynecology Volume 10 No. 1 January 2022
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v10i1.1698

Abstract

The Efficacy of Chemotherapy in Advanced-Stage Cervical Cancer on Vitamin A Serum: Efektivitas Kemoterapi pada Karsinoma Serviks Stadium Lanjut terhadap Serum Vitamin A Raissa N. Rizal; Rizal Sanif; Amirah Novaliani; Theodorus
Indonesian Journal of Obstetrics and Gynecology Volume 10 No. 2 April 2022
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v10i2.1458

Abstract

Abstract Objective: To determine the efficacy of neoadjuvant chemotherapy on changes of vitamin A serum in advanced cervical carcinoma patient. Method: A randomized clinical trial was performed in the Oncology Gynecology Polyclinic and Ward of Dr. Mohammad Hoesin General Hospital, Palembang from September 2019 to September 2020. There were 30 subjects of advanced cervical carcinoma. Vitamin A levels and tumor volume subjects were assessed before and 1 month after 3 cycles of NAC and analyzed using the Paired T Test and Wilcoxon test. The correlation between vitamin A levels and tumor volume was analyzed by using Spearman's Rho test. Data analysis was using SPSS version 22.0. Results: This study showed statistically not significant increase on vitamin A levels after 3 cycles of NAC chemotherapy (p=0.515). However, there was a significantly decrease in tumor volume after 3 cycles of NAC (p=0.000). In addition, there was a moderate negative correlation between tumor size and vitamin A (r=-0.475; p=0.008). Conclusion: It can be concluded that there was significantly decrease in tumor volume after 3 series NAC chemotherapy and the smaller tumor size, the higher level of vitamin A serum. Keywords: cervical cancer, neoadjuvant chemotherapy, randomized clinical trial, vitamin A, Abstrak Tujuan: Untuk mengetahui efektivitas kemoterapi neoadjuvan terhadap perubahan kadar serum vitamin A pada karsinoma servik stadium lanjut. Metode: Penelitian uji klinik tanpa pembanding telah dilakukan di Poliklinik dan Bangsal Onkologi Ginekologi RSUP Dr. Muhammad Hoesin Palembang sejak September 2019 hingga September 2020. Didapatkan 30 sampel karsinoma serviks stadium lanjut. Kadar vitamin A dan volume tumor dinilai sebelum dan 1 bulan setelah 3 siklus NAC dan dianalsis menggunakan uji Paired T Test dan Wilcoxon. Korelasi antara Kadar vitamin A dan volume tumor sampel dianalisis menggunakan uji Spearman Rho’s. Analisa data menggunakan SPSS versi 22.0. Hasil : Pada penelitian ini terdapat peningkatan tidak signifikan kadar vitamin A setelah kemoterapi (p = 0,515). Terdapat penurunan secara signifikan volume tumor sebelum dan sesudah kemoterapi NAC 3 seri (p = 0,000). Selain itu, didapatkan korelasi negatif sedang yang bermakna antara ukuran tumor dan kadar vitamin A ( r = -0,475 ; p = 0,008). Simpulan : Disimpulkan bahwa terdapat penurunan volume tumor setelah kemoterapi NAC 3 series dan semakin kecil ukuran tumor maka semakin tinggi kadar vitamin A dalam serum. Kata kunci: kanker serviks, kemoterapi neoadjuvan, uji klinik tanpa pembanding, vitamin A.
Treatment Approach for A Rare Case of Cervical Cancer in Pregnancy : Pendekatan Terapi pada Kanker Serviks dalam Kehamilan Yuannita I. Putri; Gumilang Wiranegara
Indonesian Journal of Obstetrics and Gynecology Volume 10 No. 2 April 2022
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v10i2.1517

Abstract

Abstract Objective: To add a new overview of cervical cancer in pregnancy and to review several treatment approaches using available guidelines. Methods: Case report. Case: A 29 years old woman, gravida 3 para 2 in 10 weeks of pregnancy, was presented with vaginal bleeding and bloody vaginal discharge. Ultrasound examination showed a 10 weeks single live intrauterine fetus and a mass on the cervix. The histopathological report revealed a poorly differentiated cervical adenocarcinoma without invasion of lymphovascular space. Patient was diagnosed with cervical carcinoma FIGO stage IB3 in 10 weeks of pregnancy. The patient opted to unpreserved the pregnancy. Radical hysterectomy with fetus in situ and bilateral pelvic lymphadenectomy was performed. Patient was referred to undergo adjuvant radiation therapy. Conclusion: Cervical cancer in pregnancy is a rare and special condition that requires individual planning for the diagnostic and treatment approaches. Keywords: cervical cancer, cervical cancer in pregnancy, fetus in situ hysterectomy, pregnancy, radical hysterectomy. Abstrak Tujuan: Untuk menambah gambaran kasus mengenai kanker serviks dalam kehamilan serta membahas pendekatan terapi menggunakan pedoman – pedoman yang ada. Metode: Laporan kasus. Kasus: Seorang perempuan berusia 29 tahun dengan G3P2 usia kehamilan 10 minggu datang dengan keluhan perdarahan pervaginam dan keputihan bercampur darah. Hasil dari USG menunjukkan adanya janin berusia 10 minggu serta massa pada serviks. Hasil pemeriksaan histopatologi menunjukkan adanya adenokarsinoma serviks berdiferensiasi buruk tanpa invasi limfovaskuler. Pasien didiagnosis dengan kanker serviks stadium FIGO IB3 dalam kehamilan 10 minggu. Pasien setuju untuk dilakukan terminasi kehamilan. Pada pasien kemudian dilakukan laparotomi histerektomi radikal dengan fetus in situ serta limfadenektomi pelvik bilateral. Pasien kemudian dirujuk untuk dilakukan terapi ajuvan dengan radiasi. Kesimpulan: Kanker serviks pada kehamilan merupakan suatu kondisi khusus sehingga perencanaan diagnostik dan manajemen terapi membutuhkan perencanaan secara individual di setiap kasusnya. Kata kunci: Kanker, kanker serviks, kanker serviks dalam kehamilan, kehamilan, , histerektomi radikal, histerektomi dengan fetus in situ.

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