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INDONESIA
Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia)
Published by Perkumpulan Obstetri dan Ginekologi Indonesia
ISSN : 23386401     EISSN : 23387335     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology Public Health
The Indonesian Journal of Obstetrics and Gynecology is an official publication of the Indonesian Society of Obstetrics and Gynekology. INAJOG is published quarterly.
Arjuna Subject : -
Articles 1,760 Documents
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Expression Collagen I and III in Anterior Vaginal Women with and without Pelvic Organ Prolapse Irianta, Trika Irianta
Indonesian Journal of Obstetrics and Gynecology Volume. 2, No. 2, April 2014
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (109.293 KB)

Abstract

Objective: To find out the expression of collagen I and III in the anterior vaginal wall of women with and without pelvic organ prolapse (POP). Method: The research was a cross sectional study, conducted in Dr. Wahidin Sudiro Husodo hospital and its networks from January 1, 2011 to April 1, 2012. The case group consisted of 35 women with POP level III and IV. The control group consisted of 35 women without POP. The expression of collagen I and III were examined by immunohistochemical test with the staining of antibody of collagen I (mouse monoclonal collagen Iab 90395) and the antibody collagen III (Mu 167 4i). The data was then analyzed by using a computer statistic program with a significance level of 0.05. Result: It was found that in the group of women with POP, there were 28 cases of expression collagen III (84%), which is significantly higher than in women without POP, found in only 20 cases (58.8%), with p=0.02. Meanwhile, in the group of POP, 9.1% of subjects showed moderate expression of collagen I, significantly less compared to the expression in the control group (35.3%), with p=0.007. For the ratio of collagen I and III, the result was weak in women with POP (58.5%) while in the control group, the result was high (85.7%). Conclusion: In terms of collagen I and III expression, there was no significant difference between the two groups. [Indones J Obstet Gynecol 2014; 2: 87-90] Keywords: collagen I, collagen III, pelvic organ prolapse, vaginal wall
Effectiveness of Pelvic Organ Prolapse Surgery in Women with Depressive Symptoms and Decreased Quality of Life Susanto, Azhar; Fauzi, Amir; Rusydi, Syakroni D; Theodorus, Theodorus; Sahab, Abdullah
Indonesian Journal of Obstetrics and Gynecology Volume. 3, No. 4, October 2015
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (94.402 KB) | DOI: 10.32771/inajog.v3i4.54

Abstract

Objective: To know the effectiveness of pelvic organ prolapse surgery in decreasing depressive symptoms (based on PHQ9) and improving quality of life in women with pelvic organ prolapse. Methods: This experimental study without control is conducted at the Obstetrics and Gynecology Department of Dr. Mohammad Hoesin Hospital Palembang/Faculty of Medicine Sriwijaya University, from October 03 2012 until May 31, 2014. Data containing selfadministrated questionnaire about depressive symptoms (PHQ9) and quality of life (PFIQ and PFDI) were recorded. Questionnaire was performed before and six months after surgery. Sample included 26 women with pelvic organ prolapse seeking pelvic organ prolapse surgery, which qualified the inclusion criteria. Data were analyzed using Chi Square and Fisher Exact test. Data analysis was done using SPSS 18.0. Results: According to paired T test there is a significant difference between mean PHQ9 score before (6.69±3.80) and 6 months after surgery (1.96±1.75)(p=0.001). Total PFIQ score decreased from 17.15±9.39 to 2.88±4.01 with 14.27±5.38 reduction. PFDI score before surgery were 29.85±15.73 and decreased to 11.50±10.99, with a reduction of 18.35±4.74. Conclusion: There was significant reduction in depressive symptoms and improved quality of life in women with prolapse after surgery, compared to before surgery. [Indones J Obstet Gynecol 2015; 3-4: 196-199] Keywords: depression, quality of life, uterine prolapse
The Risk of Ovarian Malignancy Algorithm (ROMA) as a Predictor of Ovarian Tumor Malignancy Forbes, Darlin; Sastradinata, Irawan; Agustiansyah, Patiyus; Theodorus, Theodorus
Indonesian Journal of Obstetrics and Gynecology Volume. 5, No. 4, October 2017
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (105.648 KB) | DOI: 10.32771/inajog.v5i4.568

Abstract

Object: To assess the diagnostic value of Risk of Ovarian Malignancy Algorithm (ROMA) in predicting ovarian malignancy. Methods: Diagnostic test was performed at dr. Mohammad Hoesin Hospital Palembang during June 2016 to November 2016. Data were analized with SPSS version 21.0 and Med-calc statistic. Results: A total of 57 subjects were recruited in this study. Subjects were divided into two groups: the premenopausal and postmenopausal group. Analysis with ROC curve was performed, the ROMA optimal cut-off of ROMA was 23.7% and 48.15% in the premenopausal and the post-menopausal group, respectively. With the optimal cut-off, the sensitivity was 79.41% and specivicity was 75%, positive predictive value wa 73.07% and negative predictive value 83.77% with accuracy 76.92% in diagnosing ovarian malignancy. Compared to RMI-3, the sensitivity was 65.5% and specivicity was 85.7% with accuracy 75.44%. Conclusion: ROMA is not a reliable diagnostic tools of ovarian malignancy. Keywords: CA125, HE4, ovarian cancer, risk of ovarian malignancyalgorithm/ ROMA, risk of ovarian malignancy index/RMI
The Association between Periodontal Disease on Pregnancy and the Incidence of Preterm Labor Damanik, Andoharman
Indonesian Journal of Obstetrics and Gynecology Volume. 36, No. 2, April 2012
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objective: To determine the association between periodontal disease on pregnancy and the incidence of preterm labor. Method: This was a cross sectional study. We enrolled sixty subjects, which then divided into two groups. One group comparised of thirty pregnant women preterm delivery and thirty women with preterm pregnancy. Subjects were chosen by consecutive sampling method. The subject’s teeth except Molar III were evaluated for probing depth, bleeding on probing, calculus, and the results were interpreted according to CPITN (WHO,1997). Evaluation were conducted at Dental and Oral Health Clinic at Sanglah Hospital and Gianyar Hospital. Results: The subjects characteristic was not different between the two groups, hence its influence could be avoided. Using Chi-Square test, we found that periodontal disease on pregnant women was associated with preterm birth, with prevalence ratio of 2.30 (CI 95% 1.69-3.13, p=0.011). Conclusion: Diseases on pregnant mother is associated with the incidence of preterm labor. Periodontal diseases is found twice as many in women with preterm labor compared to pregnant woman who did not experienced any signs of preterm labor. [Indones J Obstet Gynecol 2012; 36-2: 85-9] Keywords: periodontal disease, preterm birth
Deteksi Human Papilloma Virus pada sediaan sitologi Papanicolaou Smear lesi serviks: suatu uji diagnostik Tresna, K.
Indonesian Journal of Obstetrics and Gynecology Volume. 33, No. 1, January 2009
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Tujuan: Untuk mengetahui akurasi diagnostik sitologik serviks dalam mendeteksi infeksi HPV pada lesi serviks. Tempat: Pusat Kesehatan Masyarakat yang ada di Bangli (Kecamatan Tembuku dan Susut) dan Gianyar (Kecamatan Payangan), Bali. Bahan dan cara kerja: Penelitian ini memakai uji diagnostik. Pemeriksaan Pap Smear dilakukan pada semua perempuan yang sudah menikah atau sudah pernah melakukan hubungan seksual. Hasil pemeriksaan tes pap tersebut dikirim ke Laboratorium Patologi Anatomi FK UNUD/RS Sanglah Denpasar untuk pemeriksaan sitologi dan ke Laboratorium Biologi Molekuler Universitas Leiden Belanda untuk pemeriksaan PCR. Hasil: Akurasi pemeriksaan sitologi sebesar 75%, sensitivitas sebesar 67,8%, spesifisitas sebesar 77,3%, nilai prediksi positif sebesar 50%, nilai prediksi negatif sebesar 87,8%, nilai positif palsu sebesar 50%, dan nilai negatif palsu sebesar 12,2%. Kesimpulan: Pemeriksaan sitologi dapat dipakai sebagai salah satu cara untuk mendeteksi infeksi HPV. [Maj Obstet Ginekol Indones 2009; 33-1: 41-7] Kata kunci: HPV, PCR, sitologi
Hang-up IUD, New Technique for Suturing CuT-380A IUD to Uterine Fundus in Immediate Postplacental Insertion during Cesarean Delivery: Twelve Months Follow up Tjahjanto, Hary
Indonesian Journal of Obstetrics and Gynecology Volume. 2, No. 3, July 2014
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objective: The aim of this study was to evaluate the effectiveness, side effects and acceptability of postplacental CuT-380A IUD insertion using new technique for suturing to uterine fundus during cesarean section (hang up technique). Method: Prospective cohort study of postplacental IUD CuT-380A insertion during cesarean delivery. Hang-up technique consists of performing a puncture in the center of the fundus wall using straight needle into the uterine cavity and subsequently using chromic catgut no. 1 to tie the IUD using anchor knot and hanging the IUD to the fundus. Our subjects were women who underwent caesarean delivery at dr. Kariadi Hospital between 1st June 2009 to 31st April 2011 and followed up at 12 months follow-up, one woman underwent IUD removal because of severe dysmenorrhea. No perforation or expulsion was reported. Conclusion: Immediate postplacental insertion of IUD CuT-380A using hang-up technique is safe and effective. Typical use effectiveness is high (Pearl Index 0.93) and there were no reported incidents of expulsion or perforation. Acceptance and continuation rate were high, 98.15% and 95.37% respectively. [Indones J Obstet Gynecol 2014; 2-31: 132-139] Keywords: anchor knots, cesarean section, hang-up IUD, postplacental IUD insertion
Vascular Endothelial Growth Factor-C (VEGF-C) Expression Can Not Predict Pelvic Lymph Node Metastases and Response to Neo-adjuvant Chemotherapy in Bulky Cervical Cancer Hutapea, Johnson
Indonesian Journal of Obstetrics and Gynecology Volume. 36, No. 3, July 2012
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objective: To assess whether VEGF-C expression can predict the response to neoadjuvant chemotherapy and pelvic lymphnode metastases in bulky cevical cancer. Methods: Seventeen cervical cancer stage IB2 and IIA2 cases during the period of July 2009 until June 2010 were collected consecutively and given neoadjuvant chemotherapy (NAC) PVB prior radical surgery. Response to treatment was evaluated based on the change of tumour size. VEGF-C expression was examined immunohistochemically at tumour biopsy before chemotherapy. The presence of lymphnode metastases histopathologically were obtained from pelvic lymphnode dissection. The difference and correlation of response and metastases on VEGF-C expression were analized statistically. The validity of the cut off percentage of immunopositive cells to VEGF-C to identify non responding and metastatic cases was calculated with the ROC. Multivariate analysis were done to determine the predictor of no response to chemotherapy. Results: Clinical response, using the RECIST version 1.1 criteria, was found in 41.18% cases and lymphnode metastases were found in 27.27% cases. VEGF-C was expressed in all cases. Statistically, there were no significant differences and correlation in response to treatment and pelvic lymphnode metastases on VEGF-C expression. At the cut off ≥ 76% immunopositivity to VEGF-C, the sensitivity to identify no response and the specificity to identify response to NAC are 70.00% and 71.43% respectively (LR+ 2.45 and LR- 0.42); whereas at the cut off ≥ 75% immunopositivity to VEGF-C, the sensitivity to identify lymphnode metastases and the specificity to identify no lymphnode metastases are 100.00% and 75.00% (LR+ 4.0 and LR- 0). With multivariate analysis using logistic regression, the cut off ≥ 76% immunopositive cells to VEGF-C were found to have positive coefficient, largest OR and statistic score, 1.93, 6.88 (96% CI OR 0.45; 104.34) and 41 respectively, to predict non responders in a prediction score model. Conclusion: VEGF-C expression on biopsy specimen bulky cervical cancers can not differentiate cases that respond to NAC and metastases to the pelvic lymphnode from that do not. The cut off ≥ 76% immunopositive cells to VEGF-C in a prediction model can be used as an alternative predictor to identify non responders. [Indones J Obstet Gynecol 2012; 36-3: 144-9] Keywords: bulky cervical cancer, neoadjuvant chemotherapy, response and metastases prediction, VEGF-C immunohistochemistry expression
The effect of letrozole and clomiphen citrate in mature follicle count, ovulation and endometrial thickness in unovulated cycle women Maryati, Sri
Indonesian Journal of Obstetrics and Gynecology Volume. 33. No. 4, October 2009
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objective: To know the efficacy of letrozole and clomiphene citrate for ovulation induction in anovulation women. Method: During the period of January-October 2007, 44 women who met criteria for an ovulation age 18-35 years old, were done anamnesis, physical examination, USG, and hormonal analysis (FSH, LH, E2, Progesterone and Prolactin). All participants were divided into letrozole and clomiphene citrate group. For the letrozole group received 2,5 mg letrozole daily on 3th until 7th day menstrual cycle. The clomiphene citrate group received 50 mg twice a day, on 3th until 5th day menstrual cycle. On 12th menstrual cycle the ultrasound examination was perfomed to measure number of mature follicle and endometrial thickness. On the 18th day of menstrual cycle, ultrasound was perfomed to evaluate ovulation. Result: There was significant difference between letrozole group and clomiphene citrate group (p=0.04) with the number if follicles in letrozole group is 1.08 (±0.27), in clomiphene citrate group 1.40 (±0.51). There was no significant different in mean of follicle size (p=0.32). Ovulation in both groups was not significantly different (p=0.53), 59% in letrozole group and 68% in clomiphene citrate group. There was significant difference in endometrial thickness, mean of endometrial thickness in letrozole group is 8.77 mm (±2.32 mm) and in clomiphene citrate group 6,66 mm (±2.34 mm) (p
Perineal Massage during Second Stage of Labor to the Perineal Laceration Degree in Primigravida Arafah, Sitti; Lotisna, David; Tiro, Eddy
Indonesian Journal of Obstetrics and Gynecology Volume 4, No. 4, October 2016
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (82.09 KB) | DOI: 10.32771/inajog.v4i4.440

Abstract

Objective: To determine the effect of perineal massage during second stage of labor on the perineal laceration degree in primigravida. Methods: The design of this study was non randomized controlled trial by conducting massage training of the perineum to 20 obstetrics and gynecology residents. All residents had passed the normal delivery care training. Primigravida who met the inclusion criteria were included in this study. We assessed the degree of perineal laceration in this study. Data were analyzed using Chi square test in SPSS. Results: We obtained 103 subjects for massage group and 79 subjects for control group. There was a significant association between massage group and the incidence of intact perineum. In the massage group, most of perineal lacerations were first degree of laceration (52.4%); whereas, in the control group, most of them were second degree of laceration (77.2%). Statistical analysis showed a significant association between perineal massage and decreased of perineal laceration degree (p
Operasi Mikro Rekanalisasi Tuba Per Laparoskopi (Laporan Kasus) HADISAPUTRA, W.; PRIHANTORO, S.
Indonesian Journal of Obstetrics and Gynecology Volume. 30, No. 4, October 2006
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Tujuan: Untuk mengevaluasi hasil luaran dari prosedur operasi mikro rekanalisasi anastomosis tuba fallopii dengan laparoskopi. Tempat: Klinik Raden Saleh, Divisi Kesehatan Reproduksi, Departemen Obstetri dan Ginekologi, FKUI/RSUPNCM. Bahan dan cara kerja: Dilaporkan 3 kasus. Kasus pertama: Ny. A, 38 tahun, P3A0 (anak terkecil 3 tahun), sterilisasi 3 tahun, menikah 1 x, usia suami 41 tahun, ingin punya anak lagi karena sosial ekonomi membaik. Kasus kedua: Ny. I, 44 tahun, P3A0 (anak hidup 1), riwayat bekas seksio 1 x, nikah 1 x, usia suami 48 tahun, ingin punya anak lagi karena dua anak terakhir meninggal. Kasus ketiga: Ny. S, 40 tahun, P3A0 (anak terkecil 8 tahun), sterilisasi 8 tahun lalu, cerai dengan suami pertama 5 tahun lalu, menikah lagi 2 tahun lalu, ingin punya anak lagi karena desakan suami kedua, telah gagal menjalani IVF satu tahun yang lalu. Hasil: Rekanalisasi tuba dengan laparoskopi telah dilakukan pada ketiga pasien. Pada pasien pertama dan kedua dilakukan rekanalisasi pada kedua tuba dengan hasil pascaoperasi kedua tuba paten. Pada pasien ketiga tuba kanan oklusi diproksimal, sehingga hanya pada tuba kiri yang dilakukan rekanalisasi dengan hasil tuba kiri paten. Kesimpulan: Pada ketiga kasus rekanalisasi tuba dilakukan karena keinginan kuat dari masing-masing pasangan suami istri dengan alasan yang berbeda. Pada kasus-kasus yang diseleksi laparoskopi dengan teknik khusus memakai instrumen mikro KOH (dengan diameter alat masing-masing 2,5 mm) dapat ditawarkan untuk rekanalisasi tuba. Seleksi pasien dan teknik operasi yang baik adalah faktor kunci untuk mencapai angka kehamilan yang memuaskan. Hasil luaran pada ketiga kasus hanya dinilai pada tahap patensi tuba, sedangkan hasil luaran kehamilan belum dapat dinilai karena laporan ini dibuat baru 7 bulan berjalan. [Maj Obstet Ginekol Indones 2006: 30-4: 234-7] Kata kunci: rekanalisasi tuba, laparoskopi

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