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INDONESIA
Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia)
Published by Perkumpulan Obstetri dan Ginekologi Indonesia
ISSN : 23386401     EISSN : 23387335     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology Public Health
The Indonesian Journal of Obstetrics and Gynecology is an official publication of the Indonesian Society of Obstetrics and Gynekology. INAJOG is published quarterly.
Arjuna Subject : -
Articles 1,760 Documents
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The Outcomes of Primary Debulking Surgery and Neoadjuvant Chemotherapy in Advanced Ovarian Cancer Rinaldy, Dino; Andrijono, Andrijono; Sutrisna, Bambang
Indonesian Journal of Obstetrics and Gynecology Volume. 4, No. 2, April 2016
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (97.211 KB) | DOI: 10.32771/inajog.v4i2.86

Abstract

Objective: To compare the outcomes and survival rate of primary debulking surgery with neoadjuvant chemotherapy. Method: We selected advanced ovarian cancer patients from medical records. Subjects were allocated into groups of primary debulking surgery and neoajuvant chemotherapy by considering the inclusion and exclusion criteria. We analyzed the data using T test, Fisher’s exact, and chi-square. The survival rate was presented in Kaplan Meier curve, whereas the significance was tested with Logrank. We managed the data using STRATA software version 12. Result: We obtained 32 cases of primary debulking surgery group and 20 cases of the neoadjuvant chemotherapy group. Most of the subjects (44.2%) were 40-49 years old and 80.8% had delivered more than twice. The mean value of Ca-125 at admission was 3,594.8 u/ml (range 66.6 to 73,000 u/ml). Total of 31 subjects showed the serous histologic type (59.6%). There was no association between primary debulking surgery and neoadjuvant chemotherapy for the parameter of operative time, blood loss, organs injury, ICU stay, and hospital stay (p>0.05). Primary debulking surgery had a survival rate similar to neoadjuvant chemotherapy group (p=0.95). Conclusion: The perioperative outcomes of advanced ovarian cancer patients has similar result between primary debulking surgery and neoadjuvant chemotherapy. Primary debulking surgery has a survival rate similar to neoadjuvant chemotherapy group. [Indones J Obstet Gynecol 2016; 4-2: 111-115] Keywords: advanced ovarian cancer, neoadjuvant chemotherapy, primary debulking surgery
Different Doses of Intraumbilical Oxytocin on the Third Stage of Labor Islamy, Nurul; Bernolian, Nuswil; BasiR, Firmansyah; Theodorus, Theodorus
Indonesian Journal of Obstetrics and Gynecology Volume 6 No. 3 July 2018
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (109.291 KB) | DOI: 10.32771/inajog.v6i3.780

Abstract

  Objective: To compare the dose of oxytocin injected intraumbilicalltowards the duration of the third stage, blood loss volume, hemoglobinand hematocrit.   Methods: This study is a prospective randomised study with acontrol. The control group was given an intramuscular injection of10 IU oxytocin. The intervention of the three groups intraumbilicaloxytocin treatment dose of 10 IU, 20 IU and 30 IU diluted in 50 ml ofnormal saline solution and administered intraumbilically. Thesample selection by purposive sampling and the distribution groupbased on systematic random sampling (10 samples each). Data weretaken from the period April 2016-January 2017 with the inclusionand exclusion criteria. Data were analysed using Chi-square, T-test,ANOVA and Post hoc tests.   Results: Characteristics study for variables of age, occupation,parity, education, episiotomy and neonates weight showed homogeneouscharacteristics. The mean duration of the third stage forall groups was between 366.7  159.0 seconds and 440.1  244.99seconds. While the average number of postpartum haemorrhage forall group 61.894  226.3ml and 309.5  110.26 ml. There were nodifferences in the dose of oxytocin on the duration of the thirdstage (p> 0.05) and the amount of bleeding (p> 0.005). There was adifference of haemoglobin between intervention group of oxytocindose of 10 IU and 30 IU intraumbilical (p = 0.031). There was nodifference between the mean hematocrit levels between the groups(p> 0.005).   Conclusion: There were no differences in the dose of oxytocinintraumbilical towards the duration of the third stage, the amountof bleeding and hematocrit levels. The decrease of haemoglobingreater in 30 IU intraumbilical significantly. Keywords: duration of the third stage, haemoglobin and hematocrit,oxytocin intraumbilical, the amount of bleeding
Elastin Expression in Sacrouterina Ligament is Weaker in the Women with Pelvic Organ Prolapse Hasnawati, Andi
Indonesian Journal of Obstetrics and Gynecology Volume. 36, No. 4, October 2012
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (101.553 KB)

Abstract

Objective: The research aims at comparing the elastin immunolabeling in the uterosacral ligaments in women with pelvic organ prolapse and without pelvic organ prolapse (POP). Methods: The research is done at Dr. Wahidin Sudirohusodo Hospital and education networking some hospitals the Obstetrics and Gynecological School of Medicine Hasanuddin University that began in January 2011 until April 2012. This research assessing expression of elastin on 35 women with a pop level III and IV and as control is 35 women without POP. Immunolabeling of elastin valued in staining checkings immunohistokimia uses antibodies elastin ( clone no. Ba-4 1:1600; Novacastra Laboratories Ltd, UK). The research was carried out by the cross sectional study. Mixed with chi-square. Level significance used is 0.05. Results: The results showed that the elastin immunolabeling in women with POP is decline on most sample expression with the intensity of elastin is weak (74.3%). The most control with the intensity of elastin immunolabeling is moderate (48.6%). Elastin immunolabeling seem significant in women with menopause and with BMI that overweight (all with p
The Effect of Analog GnRH before Laparoscopic Cystectomy to Ovarian Reserve which was Measured with anti Müllerian Hormone at Bilateral Endometriosis Cyst Sumapraja, Kanadi
Indonesian Journal of Obstetrics and Gynecology Volume. 35, No. 1, January 2011
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (31.231 KB)

Abstract

Objective: To know the effect of preoperative GnRH-a treatment to preserve the ovary after laparoscopic excision of endometriomas by measuring antimüllerian hormonal before and after operation and analize the correlation with age and size of the endometrioma. Methods: Double blind randomized control trial, which is done to patients with bilateral endometriomas in Raden Saleh Clinic. Subject devided into groups GnRH-a and placebo. Patient was undergoing laparoscopic excision after four weeks of medication (GnRHa or placebo). AMH Serum levels was measured before preoperative medication and four weeks after operation. Result: There were eight bilateral endometriomas (25% patients requirement), 4 patient GnRH-a and four patients placebo, all with primary infertility. The average changes of AMH serum level before and after laparoscopy ovarian cystectomy in GnRH-a groups was 0.011 ng/ml and placebo groups was 1.502. The average changes of AMH serum level, in age strativication on both groups show the same result, GnRH-a 0.035 and placebo 1.681. In diameter cyst strativication, GnRH-a 0.011 and placebo 1.090. Conclusions: With the restrictiveness of the patient, this study find GnRH-a therapy initiated before laparoscopic cystectomy has better outcomes in ovarian reserve compared with placebo, and also the same result in age and size of cyst strativication analize. [Indones J Obstet Gynecol 2011; 35-1: 14-7] Keywords: laparoscopic cystectomy, GnRH-a, ovarian reserve
Acceptor Comment of PostPlacental Copper T380A Intrauterine Device Gunardi, Eka R; Malik, Adila RA; Oktavianti, Febby; Meria,, Riry; Ardianto, Fachreza; Marian, Christina
Indonesian Journal of Obstetrics and Gynecology Volume. 5, No. 1, January 2017
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (89.705 KB) | DOI: 10.32771/inajog.v5i1.460

Abstract

Objective: To describe the characteristics of subjective complaints reported by post-placental inserted intrauterine device (IUD) acceptor, especially those who used Copper T380A (CU T380A) type of IUD. Methods: Seventy-two-married women whose age ranged from 19 to 44 years old and received post-placental IUD in Dr. Cipto Mangunkusumo Hospital, Jakarta, were included in this study. Subjective complaints regarding the use of CU T380A IUD were evaluated twice including during the puerperium and six months afterwards by a direct interview. Results: Most respondents were 20-35 years old, 50% of whom were primiparous (n=36). There were 42% respondents reporting pain during insertion, 32% respondents reporting abdominal pain during the use, 22% respondents reporting menstrual disorder, 18% respondents reporting vaginal discharge, and 3% respondents complaining of having IUD repulsion. Conclusion: There are variety of subjective complaints reported after post-placental IUD use. However, most of the respondents does not complain anything. [Indones J Obstet Gynecol 2017; 5-1: 19-22] Keywords: complication, contraception, intrauterine device (IUD) post-placental, postpartum
Kesintasan Pasien Karsinoma Ovarium dan Faktor-faktor yang Mempengaruhinya di RSUPN Dr. Cipto Mangunkusumo Jakarta (Pemantauan 5 tahun) KHONSA, O.; NURANNA, L.; SUTRISNA, B.
Indonesian Journal of Obstetrics and Gynecology Volume. 31, No. 2, April 2007
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (262.487 KB)

Abstract

Latar belakang: Kanker ovarium merupakan kanker ketujuh tersering ditemukan di seluruh dunia. Beberapa tulisan menekankan pentingnya faktor-faktor prognostik untuk perencanaan dan prediksi hasil pengobatan. Kesintasan kanker ovarium yang dilaporkan bervariasi berdasarkan stadium saat ditemukan. Di Indonesia, dalam hal ini di RSUPN Dr. Cipto Mangunkusumo Jakarta, data-data seperti yang disebutkan di atas masih terbatas. Tujuan: Mengetahui kesintasan 1 tahun hingga 5 tahun dari penderita karsinoma ovarium yang ditatalaksana di RSUPN Dr. Cipto Mangunkusumo dan hubungannya dengan faktor usia, derajat dan jenis histopatologi, jenis pembedahan, adanya asites, adanya residu tumor, dan pemberian kemoterapi adjuvan. Tempat: Departemen/KSMF Obstetri dan Ginekologi Rumah Sakit Umum Pusat Nasional Dr. Cipto Mangunkusumo Jakarta. Bahan dan cara kerja: Penelitian ini menggunakan pendekatan rancangan penelitian kohort hostoris. Data yang diperoleh dianalisis dengan program Kaplan-Maier. Analisis multivariat menggunakan model cox proportional hazard regresi. Hasil: Terdapat 270 kasus kanker ovarium selama kurun waktu 1998 - 2003, hanya 178 kasus yang masuk dalam kriteria inklusi. Subjek penelitian berusia rata-rata 42,7 tahun. Sebanyak 43,8% kasus mendapatkan operasi adekuat, sementara 51,7% kasus diketahui sudah tergolong stadium III. Sebanyak 27% kasus berjenis histopatologi serosum, sisanya adalah musinosum, sel bening, endometrioid dan lainnya. Sebanyak 52 kasus (29,2%) mendapat kemoterapi secara lengkap. Kesintasan keseluruhan karsinoma ovarium adalah 89,3% (1 tahun); 69,7% (3 tahun); dan 54,8% (5 tahun). Kesintasan 5 tahun stadium I: 94,3%; stadium II: 75%; stadium III: 31%. Kesintasan 2 tahun stadium IV sebesar 11,7%. Usia muda tidak terbukti bermakna memberi kesintasan lebih baik dibanding usia lebih tua. Tindakan operasi adekuat primer, adanya asites, adanya residu tumor, jenis histopatologi, derajat diferensiasi, tidak terbukti bermakna mempengaruhi kesintasan karsinoma ovarium. Stadium FIGO terbukti bermakna sebagai faktor prognostik independen (HR 9,2 kali pada stadium III dan 26,5 kali pada stadium IV). Sementara pemberian kemoterapi terbukti bermakna sebagai faktor prognostik independen dengan efek protektif kemoterapi komplit (HR 1.53 x 10-8) dan kemoterapi inkomplit dengan HR 9.14 x 10-7. [Maj Obstet Ginekol Indones 2007; 31-2: 66-72] Kata kunci: karsinoma ovarium, kesintasan, faktor prognostik, stadium, kemoterapi
Helminth Infection in Pregnancy: Effect on Serum Albumin Level and Pregnancy outcome Ridwan, Steven; Wahyuni, Sitti; Chalid, Maisuri T
Indonesian Journal of Obstetrics and Gynecology Volume. 3, No. 1, January 2015
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (147.415 KB) | DOI: 10.32771/inajog.v3i1.21

Abstract

Objective: To determine the prevalence of helminth infection in pregnant women and its effect on albumin levels and pregnancy outcome. Method: A prospective cohort study was conducted on third trimester pregnant women presenting for antenatal care in several hospitals in Makassar. Information on subject demography was recorded using short questionnaire. Stool samples were collected to determine the presence of helminth infection. Albumin levels were measured from maternal blood and cord‐blood. Outcome of pregnancy was assessed upon delivery. Result: The prevalence of helminth infection in our subjects was 22.8%. Among 21 infected women, 17 were infected with Ascaris lumbricoides (80.9%), one with Trichuris trichiura and three with both Ascaris and Trichuris. The mean Ascaris lumbricoides intensity was 1769.3 epg (Range = 24‐11.688 epg). Helminth infections have no effect on either maternal or neonatal albumin levels (p=0.748 and p=0.480, respectively). Although it was not found to be significant (p>0.05), helminth infection seems to affect gestational age (OR 2.06, 95% CI 1.48‐2.86) and birth weight (OR 2.18, 95% CI 1.52‐3.14). Neonatal albumin level and pregnancy outcome were not affected by maternal albumin level. Conclusion: Helminth infection seems to affect pregnancy outcome in pregnant women in Makassar, but not through influence of albumin. Factors other than albumin level may responsible for such condition.
Iron Deficiency Anemia, Cystitis, and Bacterial Vaginosis Increase the Risk for Developing Preterm Labor Sumampouw, Janet; Suwiyoga, I Ketut; Negara, Ketut S.
Indonesian Journal of Obstetrics and Gynecology Volume. 5, No. 2, April 2017
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (79.614 KB) | DOI: 10.32771/inajog.v5i2.522

Abstract

Objective: To prove the association of iron deficiency anemia, cystitis, and bacterial vaginosis as risk factors for preterm labor.Methods: This study was an observational case-control study conducted at the Polyclinic and IRD of Obstetrics and Gynecology Sanglah Denpasar General Hospital Center between September and December 2015. The sample selection was done by consecutive sampling with total sample as many as 35 case samples (women with preterm pregnancy) and 35 control samples (women with aterm pregnancy).Results: Pregnant mothers with iron deficiency anemia had 4 fold increased risk of developing preterm labor (OR = 4.04, 95% CI = 1.15 to 14.16, p = 0.023) compared to those without iron deficiency anemia. Pregnant mothers with cystitis had 4 fold increased risk of preterm labor (OR = 4.00, 95% CI = 1.25 to 12.80, p = 0.016) compared to those without cystitis. Pregnant mothers with bacterial vaginosis had 3 fold increased risk of preterm frequency (OR = 3.24, 95% CI = 1.22 to 8.63, p = 0.017) compared to those without bacterial vaginosis.Conclusion: Iron deficiency anemia, cystitis, and bacterial vaginosis increase the risk for developing preterm labor.[Indones J Obstet Gynecol 2017; 5-2: 73-76]Keywords: bacterial vaginosis, cystitis, iron deficiency anemia, preterm labor
Comparison of Macrophage Migration-Inhibitory-Factor (MIF) Serum Level between 28 - 36 Weeks of Pregnancy and Delivery Riyanti, Novy
Indonesian Journal of Obstetrics and Gynecology Volume. 35, No. 3, July 2011
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (33.037 KB)

Abstract

Objective: To analyze the differences in Macrophage Migration Inhibitory Factor (MIF) serum level between 28 - 36 weeks of pregnancy and delivery, and determine the serum level of Macrophage MIF as a risk factor for preterm labor. Methods: The design of our study was cross sectional of 72 subjects who met the inclusion- and exclusion-criteria that came to Dr. Hasan Sadikin Hospital, Bandung and six satelite hospitals (in July - August 2011). Macrophage Migration Inhibitory Factor (MIF) level was measured with ELISA. Comparison of mean serum levels of MIF between 28 - 36 weeks of pregnancy and delivery was analyzed using the Mann Whitney test. MIF level, which is a risk factor for preterm delivery, was calculate with a prevalence ratio (PR) based on ROC curve. Results: Characteristics test in both groups showed homogeneous and comparable data. The mean levels of Macrophage Migration Inhibitory Factor (MIF) in 28 - 36 weeks of delivery was higher (54.433 ng/ml) compared with 28 - 36 weeks of gestation (31.765 ng/ml) with p ≤ 0.001. MIF levels > 37.684 ng/ml had a risk for preterm labor incidence 3.35 times greater than that of ≤ 37.684 ng/ml. Conclusion: Serum levels of Macrophage Migration Inhibitory Factor (MIF) at delivery was higher than that of at 28 - 36 weeks pregnancy. MIF levels > 37.684 is a risk factor for preterm labor. [Indones J Obstet Gynecol 2011; 35-3: 115-8] Keywords: Macrophage Migration-Inhibitory-Factor (MIF), preterm labor
Aspek Etik pada Pemeriksaan USG Obstetri MOSE, J.C.
Indonesian Journal of Obstetrics and Gynecology Volume. 32, No. 2, April 2008
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (45.354 KB)

Abstract

Tujuan: Untuk menguraikan beberapa aspek etik yang berkaitan dengan pemakaian USG di bidang Obstetri. Bahan dan cara kerja: Dari pengamatan pemakaian USG di Indonesia dan analisis hasil penulisan pustaka ditelusuri pelbagai aspek etik yang menyangkut aspek moral dan hukum akibat semakin meningkatnya pemakaian USG pada akhir-akhir ini. Hasil: Etik didefinisikan sebagai suatu disiplin ilmu yang mempelajari masalah moralitas. Pembahasan masalah etik di sini dimulai dari pembahasan singkat mengenai 4 prinsip dasar dari etika medis yaitu, beneficence, non-maleficence, autonomy dan justice. Masalah etik dapat muncul dari pelbagai aspek seperti peralatan USG dan teknik pemeriksaan, operator, indikasi pemeriksaan, cara pemeriksaan, dan dari beberapa kasus khusus seperti penentuan jenis kelamin, prenatal informed consent for sonogram (PICS), skrining kelainan kongenital dan salon foto janin. Kesimpulan: Masalah etik pemeriksaan USG obstetri sangat terkait dengan pelbagai aspek seperti, jenis alat dan cara pemeriksaan, siapa yang berkompeten untuk melaksanakan pemeriksaan, indikasi pemeriksaan, etiket dan beberapa hal khusus seperti penentuan jenis kelamin, PICS, skrining kelainan kongenital dan salon foto janin. [Maj Obstet Ginekol Indones 2008; 32-3: 65-71] Kata kunci: etik, USG obstetri

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