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Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia)

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Published by Perkumpulan Obstetri dan Ginekologi Indonesia

ISSN : 23386401 EISSN : 23387335 DOI : -

Core Subject : Health,

Health Professions Medicine & Pharmacology Public Health

The Indonesian Journal of Obstetrics and Gynecology is an official publication of the Indonesian Society of Obstetrics and Gynekology. INAJOG is published quarterly.

Arjuna Subject : -

Articles 1,760 Documents

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Secretory Leukocyte Protease Inhibitor in Preterm Labor and Pregnancy Sutiono, Ferriyanto; Kaeng, Juneke J; Loho, Maria FT
Indonesian Journal of Obstetrics and Gynecology Volume 6 No. 3 July 2018
Publisher : Indonesian Socety of Obstetrics and Gynecology

  Objective: To investigate the levels of secretory leukocyteprotease inhibitor (SLPI) in women with preterm labor andpregnancy.   Methods: SLPI level examination conducted to 32 samples ofpregnant women who meet the inclusion and exclusion criteria,consists of 16 preterm labor and 16 preterm pregnancy.Sample analysis carried out in Prodia Laboratory Jakarta. SLPIlevel examination used ELISA method. The obtained dataprocessed by SPSS software version 20.0 and discussed withexisting literature theory.   Results: Mean plasma SLPI level in patients with preterm laboris 30.319 ng/ml and median: 29.950 ng/ml with p value: 0.652,while the mean on preterm pregnancy is 45.975 ng/ml andmedian: 41.600 ng/ml with p value: 0.005.   Conclusion: There are significant differences of SLPI level betweenpreterm labor and preterm pregnancy. Keywords: preterm labor, preterm pregnancy, SLPI

Fetal Biometry Nomogram Based on Normal Population : an Observational Study Wibawa, Aria; Rumondang, Amanda
Indonesian Journal of Obstetrics and Gynecology Volume 6 No. 3 July 2018
Publisher : Indonesian Socety of Obstetrics and Gynecology

  Objective: To establish fetal biometry nomogram using percentilemethod based on normal population.   Methods: A descriptive retrospective study in order to establishfetal biometry nomogram using percentile method basedon normal population. Four fetal biometry measurement (BPD,HC, AC and FL) was collected from ultrasonography examinationresult in Fetomaternal Division Ultrasound Unit - AnggrekClinic and from medical record unit Dr. Cipto MangunkusumoGeneral Hospital, from January 2015 until April 2016. Databeing documented using case report form and being tabulatedusing Microsoft Excell 2011 Version 14.7.0 (161029). All datawere analyzed using SPSS 20.0 dan Matlab R2016a.   Results: There were 6169 pregnant women underwent fetalbiometry ultrasound within January 2015 - April 2016. Basedon inclusion criteria, 2798 (45%) were eligible as researchsample distributed from 12 until 42 wga. Due to evenly distributiondata, 2205 (78%) were distributed from 20 until 40 wgato develop fetal biometry nomogram. Most pregnant womenwere 28.9 years old (SD  5.74) in range of 21-30 (55%) yearsold. The youngest was 13 years old and the oldest was 45years old. Four fetal biometry were collected and distributedevenly using percentile method to establish fetal biometrynomogram. As for estimated fetal weight curve was developedby Hadlock C formula. Each biometry was calculated the 10th,50th and 90th centile curves according to gestational age. Thus,representing the fetal biometry and modified Hadlock C estimatedfetal weight nomogram based on normal population inJakarta.   Conclusion: Each biometry and modified Hadlock C estimated fetalweight were calculated in 10th, 50th and 90th centile curves accordingto gestational age represent fetal biometry nomogram based onnormal population in Jakarta. Keywords: biometry, estimated fetal weight formula, nomogram

Different Doses of Intraumbilical Oxytocin on the Third Stage of Labor Islamy, Nurul; Bernolian, Nuswil; BasiR, Firmansyah; Theodorus, Theodorus
Indonesian Journal of Obstetrics and Gynecology Volume 6 No. 3 July 2018
Publisher : Indonesian Socety of Obstetrics and Gynecology

  Objective: To compare the dose of oxytocin injected intraumbilicalltowards the duration of the third stage, blood loss volume, hemoglobinand hematocrit.   Methods: This study is a prospective randomised study with acontrol. The control group was given an intramuscular injection of10 IU oxytocin. The intervention of the three groups intraumbilicaloxytocin treatment dose of 10 IU, 20 IU and 30 IU diluted in 50 ml ofnormal saline solution and administered intraumbilically. Thesample selection by purposive sampling and the distribution groupbased on systematic random sampling (10 samples each). Data weretaken from the period April 2016-January 2017 with the inclusionand exclusion criteria. Data were analysed using Chi-square, T-test,ANOVA and Post hoc tests.   Results: Characteristics study for variables of age, occupation,parity, education, episiotomy and neonates weight showed homogeneouscharacteristics. The mean duration of the third stage forall groups was between 366.7  159.0 seconds and 440.1  244.99seconds. While the average number of postpartum haemorrhage forall group 61.894  226.3ml and 309.5  110.26 ml. There were nodifferences in the dose of oxytocin on the duration of the thirdstage (p> 0.05) and the amount of bleeding (p> 0.005). There was adifference of haemoglobin between intervention group of oxytocindose of 10 IU and 30 IU intraumbilical (p = 0.031). There was nodifference between the mean hematocrit levels between the groups(p> 0.005).   Conclusion: There were no differences in the dose of oxytocinintraumbilical towards the duration of the third stage, the amountof bleeding and hematocrit levels. The decrease of haemoglobingreater in 30 IU intraumbilical significantly. Keywords: duration of the third stage, haemoglobin and hematocrit,oxytocin intraumbilical, the amount of bleeding

Basal Temperature, Cervical Mucous, and Both Combination as Diagnostic Tools to Detect Ovulation Gunardi, Eka R; Mukti, Alexander; Situmorang, Herbert
Indonesian Journal of Obstetrics and Gynecology Volume 6 No. 3 July 2018
Publisher : Indonesian Socety of Obstetrics and Gynecology

    Objective: To make basal body temperature examination andcervical mucus as an alternative examination in detectingovulation, especially in health facilities that do not have ultrasound.   Methods: This cross-sectional study was conducted at the outpatientclinic of RSUPN Dr. Cipto Mangunkusumo in the year2016-2017. A total of 49 infertile female patients who had normalmenstrual cycles were asked to participate and performedbasal body temperature measurements, cervical mucussampling and transvaginal ultrasound examination, the dataare subsequently grouped into 3 Days Estimated Ovulation(DEO); DEO-2 days, DEO and DEO+ 2 days. Diagnostic testswere performed and accurate comparison between basal bodytemperature, cervical mucus and a combination of both werelater assessed.   Results: The best accuracy was found on cervical mucus andcombination of both with 65% in detecting ovulation, whilstthe lowest was basal body temperature (59%) with sensitivity46.7%, and specificity 78.9%. Cervical mucus in diagnosingovulation has a sensitivity of 70% and specificity 57.8%. Thecombination of temperature-cervical mucus in diagnosing ovulationhas sensitivity of 46.67% and specificity of 94.73%.   Conclusion: Cervical mucus examination has better accuracy comparedwith basal body temperature examination in detecting ovulation.Further research for validating these diagnostic tools to thewider community and not only in patients with infertility is needed.   Keywords: basal body temperature, cervical mucus, infertility, ovulationdetection, ultrasound

Rectovaginal Examination, Transvaginal Ultrasonography, and Magnetic Resonance Imaging as Diagnostic Tools for Identifying Deep Infiltrating Endometriosis Nodules Wirawan, Florencia; Marwali, Luky S; Muslim, Refni; Silalahi, Eva R; Bayuaji, Harjo S; Anindita, Astri
Indonesian Journal of Obstetrics and Gynecology Volume 6 No. 3 July 2018
Publisher : Indonesian Socety of Obstetrics and Gynecology

    Objective: To investigate the comparison between rectovaginal examination (RVT), transvaginal ultrasonography (TVUS) and magnetic resonance imaging (MRI) as diagnostic tools for identifying various Deep Infiltrating Endometriosis (DIE).   Methods: Prospective longitudinal study was done involving 31 women referred for surgical management of DIE. Calculation of sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy of RVT, TVUS and MRI for DIE were recorded.   Results: The mean age was 35.1 years. DIE were present in 95.45% of women which commonly located at uterosacral ligaments (58.33%), followed by rectovaginal (16,67%), rectosigmoid- colon (16.67%) and bladder-ureter (8.3%). TVUS had the best accuracy (RVT 50.24%; TVUS 88.85%; MRI 75.77%) among other diagnostic tools for nodules located at uterosacral ligaments (RVT 52.63%; TVUS 87%; MRI 40%) and rectovaginal (RVT 76.75%; TVUS 93.34%; MRI 80%), but it poorly identified nodules located at rectosigmoid (RVT 20%; TVUS 65.56%; MRI 88.75%) and bladder-ureteral area (RVT 50.44%; TVUS 87.66%; MRI 93.55%). RVT had good PPV (88.89%) but bad NPV (32.01%) profile, made it worth to be a screening diagnostic tool.   Conclusion: RVT was a good screening diagnostic tools as it could be done easily but was weak in diagnosing anterior DIE. TVUS gave a better diagnosis rates on DIE located at sacrouterina ligaments and rectovaginal area whereas MRI did better on bowel DIE (rectosigmoid- colon area) and urological DIE (bladder-ureteral area).    Keywords: deep infiltrating endometriosis, magnetic resonance imaging, tranvaginal ultrasonography

Compatibility between Menstrual Pictogram Assessment and Haemoglobin Assessment in Abnormal Uterine Bleeding Yulianti, Fitri; Manan, Heriyadi; Nurtjahyo, Awan; Husin, Syarif
Indonesian Journal of Obstetrics and Gynecology Volume 6 No. 3 July 2018
Publisher : Indonesian Socety of Obstetrics and Gynecology

Objective: To determine the amount of wasted blood and diagnosedAUB and determine amount of decrease in haemoglobinlevels by adjusting the examination of menstrual pictogramwith haemoglobin.Methods: Diagnostic test was conducted in the DepartmentObstetrics and Gynecology Dr. Mohammad Hoesin/Faculty ofMedicine Universitas Sriwijaya Palembang, start from January 2015through January 2017. Sample was obtained from 39 patients withabnormal uterine bleeding who meet the inclusion and exclusioncriteria. Frequency and distribution of data are described in tablesand cross analyze (cut-off point) to find cut points differencemenstrual pictogram and a decrease in haemoglobin levels usingROC curve. Accuracy is measured by the value of Kappa. Dataanalysis using SPSS version 21.Results: From 39 samples that obtained, majority characteristicsage > 35 years (59%), ideal BMI (59%) and multiparous(48.7%). From statistical analysis, there was significanceassociation between haemoglobin measurement toolsand menstrual pictogram (p = 0.063). Both measuring deviceshave compatibility in predicting the type of AUB (p = 0.047),with the degree of conformity is weak (Kappa = 0.232).Conclusion: Accuracy of menstrual pictogram examination andhaemoglobin has a weak degree of conformity, so menstrualpictogram examination can’t be used to determine a decrease inhaemoglobin levels. Menstrual pictogram menstruation only usedas an evaluation of therapeutic response.[Indones J Obstet Gynecol 2018; 6-3: 172-178]Keywords: abnormal uterine bleeding, haemoglobin, menstrual pictogram

Changes in Cortisol Levels before and after Supportive Psychotherapy in Patients with Comorbid Cervical Cancer Distress with Depression Type Nuranna, Laila; Nuryanto, Kartiwa H; Andriansyah, Andriansyah; Elvira, Sylvia D; Sutrisna, Bambang
Indonesian Journal of Obstetrics and Gynecology Volume 6 No. 3 July 2018
Publisher : Indonesian Socety of Obstetrics and Gynecology

Objective: To prove the success of supportive psychotherapy thatwas provided as a distress therapy on advanced cervical cancer.Knowing the prevalence of distress type of depression in patientwith epithelial cervical cancer, proving the benefits of psychotherapysupportive for distress can decreasing cortisol level in cervicalcancer patient, can assess distress thermometer score, HAM-D17score and scoring incident predictors of distress with depressiontype.Methods: There were 32 subjects from 71 advanced cervical cancerpatients had mild-moderate depression. Then randomizationblocking was performed to determine a subject who entered thetreatment group (n = 16) who got supportive psychotherapy orcontrol group who got common psychotherapy (n = 16). All ofparticipants assessed the distress level with cortisol value, distressthermometer score, and HAM-D17 score before and after they gotsupportive psychotherapy.Results: After the intervention of psychotherapy in the treatmentgroup decreased HAM-D17 score, the average decline 7.53 (SB 3.34).The mean decreasing in the control group was 3.98 (SB 2.85). Thereis a significant difference in mean reduction in HAM-D17 scores ontreatment and control groups with p = 0.003 (p <0.005). There wasdecreasing blood cortisol level in the treatment group amounted to39.43, while the control group there was a drop of 1.59. The reductionof cortisol level in the treatment group and the control has a pvalue0.302. After got supportive psychotherapy, found a decreasingthe average value of the thermometer distress in the treatmentgroup 3.02 and the control group 2.51, with a p value more than0.492.Conclusion: There were 45% of cervical cancer patients in the clinicexperiencing distress disorder with depressive type. The bloodcortisol level could be decreased by giving supportive psychotherapywith a mean decrease of 39.43 nmol/l. There was a significantreduction in the level of depression (HAM-D17 score) of 7.53 pointsand distress thermometer impairment by 3 points after givensupportive psychotherapy. Obtained scoring predictors for theoccurrence of distress type of depression in patients with advancedcervical cancer with a sensitivity of 46.15% and a specificity of89.47%.[Indones J Obstet Gynecol 2018; 6-3: 179-187]Keywords: cervical cancer, cortisol, distress, distress thermometer,HAM-D17 score

Human Papilloma Virus16 and 18 Infection and the Cervical Cytology Changes in Combined Hormonal Contraceptive Users Darkuthni, Merdyana; Tahir, Mardiah; Tumedia, Josephine L
Indonesian Journal of Obstetrics and Gynecology Volume 6 No. 3 July 2018
Publisher : Indonesian Socety of Obstetrics and Gynecology

    Objective: To evaluate the correlation between HPV-16 and 18infection and the cervical cytology changes among combinationhormonal contraceptives users.   Methods: A cross-sectional study involved 40 women usingcombined hormonal contraceptive (oral or injection/DMPA contraceptive)and 40 women of non-hormonal contraceptive users wasconducted in Dr. Wahidin Sudirohusodo hospital, some affiliatedhospitals of Department of Obstetrics and Gynecology Faculty ofMedicine, Universitas Hasanuddin and a private clinic in Makassarfrom November 2015 and April 2016. HPV 16 and 18 genotypingin cervix using PCR method and cervical cytology changes usingliquid-based cytology (LBC) method were performed. HPV infectionand cervical cytology changes were analysis based on Fisher’s testand chi-square test.   Results: A significant difference found only in parity (p<0.05)between users and control of baseline characteristics. Neither usersnor control were significantly associated with HPV-16 and 18infection and changes in cervical cytology.   Conclusion: Combined hormonal contraceptives are not correlatedwith HPV-16 and 18 infection and changes in cervical cytology. Keywords: cervix, combined hormonal contraceptive, human papillomavirus

Vaginal Delivery in Placental Abruption Adjie, JM Seno; Ghazali, M Farid; Khusen, Denny
Indonesian Journal of Obstetrics and Gynecology Volume 6 No. 3 July 2018
Publisher : Indonesian Socety of Obstetrics and Gynecology

    Objective: To describe the case of vaginal delivery in placental abruption.   Methods: A case report   Results: In the case of placental abruption, we could perform vaginal delivery.   Conclusion: The treatment of placental abruption can be vaginally or by cesarean section depending on the severity of disease, gestational age, and state of the mother and fetus. Keywords: IUFD, placental abruption, vaginal delivery

Endoglin Expression (CD105) in Ephithelial Ovarian Cancer Jumsa, Rizkinov; Rambulangi, John; Arifuddin, Sharvianty; Miskad, Upik
Indonesian Journal of Obstetrics and Gynecology Volume 6. No. 2 April 2018
Publisher : Indonesian Socety of Obstetrics and Gynecology

Abstract Objective: Endoglin ( CD105 ) is one of the factors that play a role in vascular development , angiogenesis and vascular homeostasis. The aim of this research is to address the endoglin expression (CD105) in primary tumor and metastasis tumor (omentum) and their relation with clinicopathological factor: stadium, differentiation level, and histological epithelial ovarian cancer. Method: The research was performed at Public Service Hall of Dr. Wahidin Sudirohusodo Hospital and educational networking hospital of Obstetrics and Gynecology Departement of Medical Faculty Hasanuddin University Makassar. The research design is cross sectional with 55 samples consisting of 55 samples of primary tumor and 55 matastasis tumor. Imunohistochemistry examination was performed to all samples. Result:The results show a significant relation between endoglin (CD105) at omentum metastasis tumor and stadium and cell differentiation level of epithelial ovarian cancer. There is no significant relation between endoglin (CD105) expression at primary tumor of ovarian cancer and stadium and differentiation and type of histopathological cell. In addition, there is no significant relation between endoglin expression (CD105) at omentum metastasis tumor and type of histophatological cell of ovarian cancer. There is a significant correlation (strong category) between endoglin expression at omentum metastasis tumor and endoglin expression at primary tumor of epithelial ovarian cancer. Conclusion: Endoglin expression in ovarian cancer metastatic tumor to omentum is correlated to clinical stage and differentiation level of ovarian cancer. And endoglin is one of the pro angiogenic and pro metastasis factors. Keywords:epithelial ovarian cancer, endoglin expression, CD105, immunohistochemistry  

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eko subaktiansyah

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