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JURNAL GIZI INDONESIA

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Search results for , issue "Vol 3, No 1 (2014)" : 9 Documents clear

Efek pemberian Chlorophyllin terhadap kadar nitric oxide dan malondialdehida tikus hiperkolesterolemia Pontang, Galeh S; Johan, Andrew; Subagio, Hertanto W
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 3, No 1 (2014)
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Background : Endothelial dysfunction is well-known as an early stage of atherosclerosis. Increased oxidative stress inhypercholesterolemia triggers endothelial dysfunction that is characterized by decreased biological availability ofnitric oxide (NO). Experimental studies showed that chlorophyllin had an effective antioxidant activity.Objectives : To determine the effect of chlorophyllin on nitric oxide (NO) and malondialdehyde (MDA) level ofhypercholesterolemic rats.Methods : Post test only randomized control groupusedtwenty four male Sprague Dawley rats were randomly dividedinto four groups: without treatment (technical control/K1), hypercholesterolemic (negative control/K2),hypercholesterolemic with chlorophyllin at dose of 1,8 mg/200 g/d (P1) and hypercholesterolemic with chlorophyllin atdose of 3,34 mg/200g/d (P2). Chlorophyllin was dissolved in water and was given via nasogastric tube for 21 days afterthe rats got hypercholesterolemia. Total cholesterol level of blood was measured by CHOD-PAP method, level of NOplasma was measured by Griess reaction and level of MDA plasma was measured by TBARS method. Hypothesis testwas analyzed by One Way Anova continued by Post hoc LSD test and Kruskall Wallis by significant level of 0,05.Results :NO plasma level was the lowest in group P2 (0.203+0.015 Î¼M) and the highest in the group K2 (0,224Â±0,001Î¼M), but no difference of NO plasma level among groups (p = 0.118). There were differences in MDA plasma levelamong the groups (p = 0.001). P1 and P2 groups had lower MDA plasma level than K2 (2.40+0.11 nmol/ml), indicatedby (1.94 +0.07 nmol/ml, p=0.0001) and (1,37 +0.13 nmol/ml, p=0.0001) respectively, but still higher than K1(0.94+0.05 nmol/ml, p=0.0001).Conclusion : The treatment of chlrophyllin does not have an effect of NO plasma level, but gives an effect of lowerMDA plasma level.

Kadar radikal superoksid (O2-), nitric oxide (NO) dan asupan lemak pada pasien hipertensi dan tidak hipertensi Astutik, Pudji; Adriani, Merryana; Wirjatmadi, Bambang
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 3, No 1 (2014)
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Background: Hypertension closely related to impaired endothelial dependent vasodilation due to a decline in theavailability of nitric oksid (NO) and high fat intake, decreased Nitric Oksid caused due to increased levels ofsuperoksid.Objective: to analyze the differences in the levels of Superoksid Radical (O2-), Nitric oxide (N0) and fat intake inpatients with hypertension and not hypertension .Methods: this research is cross sectional, research amount sampelnya taken at random. 24 respondent patientsconsisting of 12 cases control, and 12 the age of 65 40- tahun.pengambilan samples conducted in outpatient installationregional general hospital Sidoarjo. Done bseline superoksid levels, nitric oxide and recall fat intake.Results: the average rate of Superoksid respondents not hypertension 0.250Â± 0, 034U/mL, 0,314Â± 056U/mLhypertension, Average levels of Nitric oksid respondents not hypertension 116,083Â± 46,962Î¼ M, of which hypertension72,333Â± 40,51Î¼ M, average consumption of fat respondents not hypertension 41,65Â± 8, 32gram, 51,52Â± 6,74gramhypertension . Based on the test results the difference against Superoksid levels of both research groups using a t-testtwo samples are free retrieved the value p < 0,05 (p = 0,004), NO content retrieved the value p < 0,05 (p = 0,023), fatintake obtained the value of p < 0,05 (p = 0,004) which means that there is a meaningful difference in the levels ofSuperoksid, Nitric oxide and the level of fat intake among respondents with no hypertension and hypertension.Conclusion: there is a radical difference in the levels of Superoksid, NO (Nitric Oxide) and fat intake in patients withhypertension and not hypertension.

Pengaruh pendidikan gizi terhadap pengetahuan dan sikap tentang gizi anak Sekolah Dasar Nuryanto, Nuryanto; Pramono, Adriyan; Puruhita, Niken; Muis, Siti Fatimah
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 3, No 1 (2014)
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Background: Nutrition education is one method to change the knowledge and attittude of nutrition on school children.The study aimed to see the effect of nutrition education on knowledge and attitude of nutrition among school children.Methods: The study was one group pre-post test design of a quasi experimental design. Subjects were 99 schoolchildren randomly selected through multi stage sampling method among the 4th, 5th, and 6th graders. They were givennutrition education using posters and pocket books in children meeting for three months. The data of knowledge andattitude were collected through interview using structure questionares. The differences in knowledge attitude andpractice of of nutrition among school children were tested by wilcoxon test.Results: The mean of knowledge about nutrition among school children before nutrition education is 66,45Â±9,6%increasing to 71,61Â±9,3% after nutrition education. Median of attitude before nutrition education is 70,31% increasingto 75% after nutrition education. The result showed that there was an effect of nutrition education on knowledge andattitude of school children.Conclusion: Nutrition education can improve knowledge and attitude of school children.

Efek ekstrak daun sirsak (Annona muricata Linn) terhadap profil lipid tikus putih jantan (Rattus Norvegicus) Wurdianing, Indrawati; Nugraheni, SA; Rahfiludin, Zen
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 3, No 1 (2014)
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Background: Lipid profile effects is a risk factor for Coronary Heart Disease. Soursop leaves (Annona muricata L) isa traditional medicine plant containing metabolic compounds that contribute to the improvement of the lipid profile.Objective: To determine the effects of soursop leaves extract on lipid profile (total cholesterol, LDL cholesterol, HDLcholesterol and triglyceride).Methods: An experimental study using randomized pre-posttest with control group design. Sample consisted of 28 maleWistar rats, were divided into four groups. The control group (K) was only given High Fat High Cholesterol (HFHC)diet and treatment groups (P1, P2, P3) were given a HFHC diet plus Annona muricata L extract with doses of 100, 200and 300 mg/kgBB per day for 28 days respectively. Data were analyzed by Wilcoxon test, Kruskal-Wallis and MannWhitney.Results: The mean total cholesterol level significantly decreased in the treatment group P1 (p = 0.028) from 60.7 mg/dl(47.6-75.3) to 45.5 mg/dl (38.4-62.4). Mean HDL cholesterol level significantly increased in the treatment group P2(p=0.043) from 26.0 mg/dl (19.7-35.3) to 27.9 mg/dl (18.8-38.0). The mean levels of LDL cholesterol and triglyceridedecreased but not significantly.Conclusion: The administration of Annona muricata L extract can decrease total cholesterol and increase HDLcholesterol significantly.

Faktor risiko stunting pada anak umur 6-24 bulan di kecamatan Penanggalan kota Subulussalam provinsi Aceh Lestari, Wanda; Margawati, Ani; Rahfiludin, Zen
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 3, No 1 (2014)
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Background : Aceh is one of the province in Indonesia with high prevalence of stunting that is 39% compared withnational 35,6%. Subulussalam has a highly proportion of stunting.Objective : This study was aimed to analyze the risk factors for stunting among children between 6-24 months old.Methods : The design was case-control study, the subjects were children between 6-24 months with 55 stunted and 55normal. The subjects chosen by consecutive sampling. The risk factors were education levels and employment of parent,family income, suffering from diarrhea and URTI, energy and protein intake, height of the parent, birth weight,exclusive breastfeeding, the time of complementary feeding, parenting style and source of clean water. Data analysisusing the odds ratio with 95% confidence interval and regression analysis.Results : The risk factors for stunting were low income of family (OR=8,5, 95%CI: 2,68-26,89), suffering from diarrhea(OR=5,04, 95%CI: 1,84-13,81) and URTI (OR=5,71, 95%CI: 1,95-16,67), inadequate of energy (OR=3,09, 95%CI:1,02-9,39) and protein intake (OR=5,54, 95%CI: 2,43-12,63), short stature of the parent (OR=11,13, 95%CI: 4,37-28,3), low birth weight (OR=3,26, 95%CI: 1,46-7,31), not exclusively breastfeeding (OR=6,54, 95%CI: 2,84-15,06),giving complementary feeding too early (OR=6,54, 95%CI: 2,84-15,06), and poor parenting style of feeding practices(OR=4,59, 95%CI: 2,05-10,25), child hygiene practices (OR=3,26, 95%CI: 1,46-7,31) and treatment of childrenpractices (OR=2,46, 95%CI: 1,13-5,34). Regression analysis showed that the dominant risk factor for stunting wasshort stature of the parent (OR=13,16, 95%CI: 3,72-46,52).Conclusions : The dominant risk factor for stunting was short stature of the parent.

Pengaruh pemberian probiotik Lactobacillus helveticus Rosell-52 dan Lactobacillus rhamnosus Rosell-11 terhadap kadar limfosit lanjut usia Wahyuningsih, Retno; SS, Darmono; Margawati, Ani
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 3, No 1 (2014)
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Background: Infectious disease remains a health problem for the elderly. The elderly are susceptible to infection,because the body's ability to fight infection decreases immunity. The immune status can be improved through the effortsof immunization, and nutrition. However the elderly are not sufficient to meet the nutritional needs of food, so probioticcould support nutritional adequacy.Objective: Analyze the effect of probiotic Lactobacillus helveticus Rosell-52 and Lactobacillus rhamnosus Rosell-11 onlevels of lymphocytes in the elderly in Tresna Elderly Social Institution Puspakarma Mataram, West Nusa Tenggara.Methods: This was quasi-experimental study, randomized pre-post control group design. The population is elderly aged60-75 years, involving 45 subjects were divided randomly into two groups, namely the treatment groups givenprobiotics and the control group was given a placebo. Probiotics were given for 4 weeks, with the provision of onecapsule a day. Immunity status in this study was lymphocytes. Data examined included the intake of nutrients (protein,vitamin A, vitamin C, vitamin E, Fe, Zn), health status, quality of sleep, and levels of lymphocytes in the elderly. Datawere analyzed using bivariate with different test Independent sample t-test, Mann-Whitney U test, Spearman, Pearson,and Paired t-test.Results: Increasing number of lymphocytes were significantly in the treatment group (Ï‡ Â± SD: 1.84 Â± 1.85) and in thecontrol group (0.95 Â± 5.0). There is no relationship between intake (protein, vitamin A, vitamin C, vitamin E, Fe, Zink),physical health status, and quality of sleep with levels of lymphocytes.Conclusion: Probiotics in 4 weeks is proven to increase the number of lymphocytes in the elderly.

Pengaruh pemberian yoghurt sinbiotik tanpa lemak ditambah tepung gembili terhadap kadar kolesterol ldl tikus hiperkolesterolemia Towil, Afida Soucha; Pramono, Adriyan
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 3, No 1 (2014)
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Background: Yoghurt is probiotics a fermented milk product, produced by lactic acid bacteria and has being proved tolower cholesterol. The addition lesser yam of inulin could be the hypocholesterolemic effect.Objective:The aim of this study was to analyze the effect of non-fat yoghurt synbiotic added with of lesser yam flouradministration towards LDL cholesterol level in hypercholesterolemic rats.Methods: True experimental study with pre-post test was conducted to 24 male Wistar ratshypercholesterolemiainducedwhich grouped using simple random sampling. Samples was divided into 4 groups by simple random sampling:control, P1 (consumed 2 ml dose), P2 (consumed 3 ml dose), and P3 (consumed 4 ml dose), each group were containedof 6 rats. Non-fat yoghurt synbiotic added with oflesser yam were administered for 14 days intervention. LDLcholesterol level were determined using CHOD-PAP methods. All datas collected were analyzed using paired t-test andOne Way ANOVA followed by LSD test at 95% confidence level.Results: LDL cholesterol level was decreased significantly after 14 days intervention (P1=16.63% (p=0.033);P2=20.72% (p=0.034); P3=20.51% (p=0.013)). P2 was the highest decreasing of LDL cholesterol compared to P3,with the provision of non-fat yoghurt synbiotic added with of lesser yam flour for about 3 ml.Conclusion: Non-fat yoghurt synbiotic added with of lesser yam flour was significant lowering LDL cholesterol level inhypercholesterolemic rats.

Pengaruh variasi pemberian Snack bar ubi jalar kedelai hitam terhadap Kadar Superoksida Dismutase (SOD) darah Ayustaningwarno, Fitriyono; Sabuluntika, Novita
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 3, No 1 (2014)
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Background: Snack bar from sweet potatoes and black soybeans is low GI, fat and calorie snack which haveantioxidant content, such as Î²-carotene, anthocyanin, isoflavone, and antioxidant activity, so can be an alternativesnack for patients with DM type 2. Antioxidants intake can prevent the oxidative stress that lead micro- and macrovascularcomplications in DM type 2. Antioxidant intake may preserve endogen antioxidant capacity, which is can bedetermined by analyzing SOD concentration.Objective: analyze effect variety of Snack bar from sweet potatoes and black soybeans consume to SOD concentration.Methods: experimental post-pretest research used 3 varieties of sweet potatoâ€™s color (red, yellow, and purple)interventions. SOD concentration was analyzed by colorimetric. Statistic data was analyzed by dependent t-test andOne Way Anova.Results: No different between groups interventions Snack bar from purple, yellow or red sweet potatoes (p=0,122).Group with snack bar from purple sweet potatoes intervention has lowest SOD decreasing percentage among otherintervention groups.Conclusion: Consume snack bar form purple sweet potatoes and black soybeans can preserve SOD concentrationbetter than consume snack bar form yellow or red sweet potatoes and black soybeans

Pengaruh mikronutrien taburia terhadap perkembangan motorik anak usia 24-48 bulan yang stunting (Studi di Tanjungkarang Barat Kabupaten, Bandar Lampung) Nugroho, Arie; Susanto, Hardhono; Kartasurya, Martha Irene
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 3, No 1 (2014)
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Background: Stunting is associated to the developmental delays of gross motor and fine motor skills. Previous studiedstate that micronutrient supplementation has a positive effect on both motor skills development in children aged under24 months.Objective: The aim of this study was to analysis the effect of micronutrient sprinkle on motor development amongstunted children aged 24 to 48 months.Methods: A quasi-controlled experimental group study with a total of 63 stunting age 24-48 months are divided intotreatment group (31 children) and controls (32 children). Treatment group received micronutrient sprinklesupplementation once in two days for two months. Fine and gross motor development was measured by DDST II beforeand after intervention.Results: There was no difference in age, sex, energy intake, protein, zinc, folic acid and developmental delaypercentage before treatment. The percentage of fine motor delays before treatment was 48.4% in the treatment groupand 53.1% in the control group, while the percent of gross motor delay was 32.3% in the treatment group 34.4% in thecontrol group. After intervention, the percentage of fine motor developmental delays significant decreases 25.8%, in thetreatment group and 34.4% in the control group, while the percentage of gross motor delay in the control groupsignificant decreased to 12.5%, but not significant decreased to 16,1% in the treatment group. Confounding variablesin this study were include energy adequacy level, protein adequacy level, zinc, iron and folic acid. There was nodifferences percentage of developmental delays on fine motor (p= 0,514) and gross motor (p= 0,571) after theintervention and after controlling with confounding variables.Conclusion: Micronutrient sprinkle supplementation for two months did not influence the development of fine motorskills gross motor skills on stunting preschooler children age 24 to 48 months

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