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SRIWIJAYA JOURNAL OF MEDICINE
Published by Universitas Sriwijaya
ISSN : -     EISSN : 26223589     DOI : -
Core Subject : Health, Science,
Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health
Sriwijaya Journal of Medicine (SJM) is a scientific journal managed by Faculty of Medicine Universitas Sriwijaya, Indonesia. It publishes original research articles and reviews in Biomedical Sciences, Medicine (Neurology, Cardiovascular, Respiratory, Gastrointestinal, Urogenital, Endocrine and Metabolism, Integument, Mental Health, Obstetry and Gynecology, Ophtalmology, ENT, Musculosceletal) and Public Health Medicine. Sriwijaya Journal of Medicine (SMJ) published three times a year (January, April, October).
Arjuna Subject : Kedokteran - Anatomi
Articles 335 Documents
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Association Between Remnant Cholesterol, Non-HDL Cholesterol, and HbA1c in Statin-Treated Patients with Type 2 Diabetes Mellitus Khoirun Mukhsinin Putra; Yulianto Kusnadi; Ratna Maila Dewi; Alwi Shahab
Sriwijaya Journal of Medicine Vol. 9 No. 2 (2026): Vol 9, No 2, 2026
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/sjm.v9i2.406

Abstract

Type 2 diabetes mellitus (T2DM) is strongly associated with an increasing risk of cardiovascular complications and is often paired with atherogenic dyslipidemia. Remnant cholesterol (RC) and non-high-density lipoprotein (non-HDL) cholesterol are increasingly recognized as markers reflecting the entire burden of atherogenic lipoproteins. Nevertheless, how these parameters relate to each other and to glycemic control remains insufficiently explored. This was a cross-sectional research designed to assess the correlation between RC and non-HDL cholesterol, along with their association with glycemic status in patients with T2DM. A cross-sectional study was conducted using secondary clinical data obtained from medical records of patients attending the Integrated Diabetes Clinic of Dr. Mohammad Hoesin General Hospital, Palembang, Indonesia, between November and December 2025. All participants were receiving statin therapy. Remnant cholesterol was calculated as total cholesterol minus LDL cholesterol minus HDL cholesterol, whereas non-HDL cholesterol was calculated as total cholesterol minus HDL cholesterol. Correlation analysis was performed using Spearman’s rank correlation coefficient because all variables showed non-normal distributions. A total of 100 participants were analyzed. The results showed a moderate positive correlation between remnant cholesterol and non-HDL cholesterol (r = 0.618; p < 0.001). Conversely, no statistically significant correlation was identified between HbA1c and non-HDL cholesterol (r = –0.180; p = 0.074). These findings indicate that remnant cholesterol was positively correlated with non-HDL cholesterol, whereas HbA1c was not. Because RC and non-HDL cholesterol share calculated lipid components and all participants were receiving statin therapy, these findings should be interpreted cautiously.
Antimicrobial Prescribing Profile at the Dermatovenereology Outpatient Clinic of Universitas Sebelas Maret Hospital Surakarta from August to December 2024 Hillary Yoedyanto; Labitta Aquaira; Rina Purnamasari; Muhammad Irawanto; Alamanda Murasmita
Sriwijaya Journal of Medicine Vol. 9 No. 2 (2026): Vol 9, No 2, 2026
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/sjm.v9i2.407

Abstract

Antimicrobial agents, both topical and systemic, are commonly used in dermatology for the management of infectious skin diseases. Data regarding antimicrobial prescribing patterns in dermatovenereology outpatient settings in Indonesia remain limited. This study aimed to describe the antimicrobial prescribing profile at the Dermatovenereology Outpatient Clinic of Universitas Sebelas Maret Hospital, Surakarta. A retrospective descriptive study was conducted using electronic medical records and outpatient pharmacy data. Prescriptions containing antimicrobial agents issued at the Dermatovenereology Outpatient Clinic of Universitas Sebelas Maret Hospital between August and December 2024 were analyzed. Of 2,383 dermatovenereology outpatients, 510 (21.4%) received an antimicrobial agent. Topical antimicrobials were prescribed more frequently than systemic antimicrobials. The most commonly prescribed topical antimicrobials were 2% mupirocin cream (42.94%), 0.1% gentamicin cream (23.14%), and 2% fusidic acid cream (7.06%). Among systemic antimicrobials, azithromycin was the most frequently prescribed (13.3%), followed by cefixime (5.69%), metronidazole (2.75%), clindamycin (1.96%), doxycycline (1.76%), and cefadroxil (1.37%). Antimicrobial prescribing at the Dermatovenereology Outpatient Clinic of Universitas Sebelas Maret Hospital was dominated by topical antimicrobial agents, particularly 2% mupirocin cream and 0.1% gentamicin cream, while azithromycin was the most frequently prescribed systemic antimicrobial. These findings provide baseline data for monitoring antimicrobial use and may support antimicrobial stewardship initiatives in dermatology practice.
Drug Utilization Pattern Study of Magnesium Sulphate In Pregnant Patients with Preeclampsia at Mohammad Hoesin Hospital, Palembang Nyayu Nurhaliza Hasanah; Nia Savitri Tamzil; Syarinta Adenina; Debby Handayati Harahap; Evi Lusiana; Rulan Adnindya
Sriwijaya Journal of Medicine Vol. 9 No. 2 (2026): Vol 9, No 2, 2026
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/sjm.v9i2.414

Abstract

Preeclampsia is a hypertensive disorder of pregnancy characterized by systolic blood pressure ≥140 mmHg or diastolic blood pressure ≥90 mmHg on two measurements taken at least 4 hours apart after 20 weeks of gestation, accompanied by new-onset proteinuria. Preeclampsia with severe features may progress to eclampsia. Magnesium sulphate is recommended for seizure prophylaxis because of its effectiveness and relatively low risk of serious neonatal adverse effects. This study aimed to evaluate the appropriateness of magnesium sulphate prescribing in pregnant women with preeclampsia at Mohammad Hoesin Hospital Palembang based on predefined prescribing indicators. This descriptive drug utilization study was conducted from August to September 2024 using total sampling of medical records that met the inclusion criteria, resulting in 45 samples. Data were analyzed using SPSS version 27.0 for MacOS and presented as frequency distributions. The prevalence of preeclampsia was 77.46%. All patients had preeclampsia with severe features (100%); most were housewives (68.9%), multiparous (55.5%), multigravida (80%), and had a gestational age ≥34 weeks (71.1%). Magnesium sulphate use was appropriate regarding indication (100%), dosage regimen (100%), duration of administration (100%), and absence of contraindications (100%). Eighteen patients (40%) received concomitant nifedipine, while 27 patients (60%) had no identified potential drug interactions. Overall, magnesium sulphate uses in pregnant women with preeclampsia at Mohammad Hoesin Hospital Palembang met the evaluated rational drug use criteria.
Nutritional Status Profile in Children with Acyanotic Congenital Heart Disease: Analysis of Relationship with Diagnosis and Defect Size Devy Kusmira; Ria Nova; Fani Paulina; Sheila Stephanie Chandra
Sriwijaya Journal of Medicine Vol. 9 No. 2 (2026): Vol 9, No 2, 2026
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/sjm.v9i2.416

Abstract

Congenital heart disease (CHD) occurs in approximately 9 per 1,000 live births and can impair growth due to chronic hemodynamic burden, feeding difficulties, and increased energy demands. This study aimed to describe the nutritional status of children with acyanotic CHD and assess its relationship with diagnosis and defect size. A cross-sectional analytical study was conducted involving 34 children with patent ductus arteriosus (PDA) or ventricular septal defect (VSD) scheduled for transcatheter closure. Nutritional status was determined using anthropometric measurements, while defect size was assessed by 2D echocardiography. Associations were analyzed using Spearman correlation and Kruskal-Wallis tests. Of the 34 subjects, 58.8% (n=20) had good nutritional status, 29.4% (n=10) were undernourished, and 11.8% (n=4) had severe malnutrition. Malnutrition was slightly more common in VSD (50.0%) than PDA (37.5%). Defect size ranged from 2.0–7.0 mm, with a median of 5.0 mm, and most defects were classified as small to moderate. Median defect sizes were 5.0 mm in both the good nutritional status and undernutrition groups and 4.5 mm in the severe malnutrition group, with no significant difference (p=0.549). Nutritional status was also not significantly correlated with absolute defect size (ρ=0.128; p=0.473). Although most children had good nutritional status, malnutrition remained prevalent (41.2%). These findings suggest that malnutrition in CHD is multifactorial and cannot be explained solely by the anatomical diameter of the defect.
Correlation Between Prematurity and Abnormal Hearing-Screening Outcomes in a Tertiary Pediatric Population: A Retrospective Study Fani Paulina; Devy Kusmira; Depi Jufri
Sriwijaya Journal of Medicine Vol. 9 No. 2 (2026): Vol 9, No 2, 2026
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/sjm.v9i2.417

Abstract

Prematurity is a recognized risk factor for neonatal hearing impairment, but its independent contribution may be difficult to distinguish from coexisting neonatal morbidities and intensive-care exposures. This study aims to assess the association between prematurity and abnormal hearing-screening outcomes and to describe the distribution of abnormal outcomes according to selected perinatal risk factors. This retrospective observational study included 349 participants who underwent otoacoustic emissions and/or auditory brainstem response testing. Participants were classified according to gestational age at birth as preterm (<37 completed weeks) or term (≥37 completed weeks). An abnormal outcome was defined as a “refer” result in either ear on either test. Groups were compared using the chi-square test and odds ratio (OR). Of 349 participants, 240 (68.8%) were born preterm and 109 (31.2%) were born at term. Overall, 169 participants (48.4%) had an abnormal hearing-screening result. The proportion was 45.8% (110/240) among premature participants and 54.1% (59/109) among term participants, with no significant difference (χ²=1.746; p=0.186; OR=0.72, 95% CI 0.45–1.13). High proportions of abnormal screening outcomes were observed among participants with documented ototoxic drug exposure (13/13, 100%), asphyxia (27/36, 75.0%), and hyperbilirubinemia (13/19, 68.4%). Prematurity alone was not associated with abnormal early hearing-screening outcomes in this high-risk population. The high referral rate supports universal screening and targeted audiological follow-up, particularly for participants with ototoxic exposure, asphyxia, or hyperbilirubinemia.

Page 34 of 34 | Total Record : 335

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