Molekul: Jurnal Ilmiah Kimia
MOLEKUL is a peer-reviewed journal of chemistry published by the Department of Chemistry, Faculty of Mathematics and Natural Sciences, Jenderal Soedirman University, Indonesia. Publishing frequency 2 issues per year, on May and November. This Journal encompasses all branches of chemistry and its sub-disciplines including Pharmaceutical, Biological activities of Synthetic Drugs, Environmental Chemistry, Biochemistry, Polymer Chemistry, Petroleum Chemistry, and Agricultural Chemistry.
Articles
331 Documents
<![CDATA[Degradation of Phenol By Photolysis Using N-doped TiO2 Catalyst ]]>
<![CDATA[Safni Safni]]>;
<![CDATA[Mechy Rezita Wahyuni]]>;
<![CDATA[Khoiriah Khoiriah]]>;
<![CDATA[Yulizar Yusuf]]>
<![CDATA[ Molekul Vol 14, No 1 (2019) ]]>
Publisher : <![CDATA[Universitas Jenderal Soedirman ]]>
Show Abstract
|
Download Original
|
Original Source
|
Check in Google Scholar
|
Full PDF (285.977 KB)
|
DOI: 10.20884/1.jm.2019.14.1.447
<![CDATA[Phenol (C6H5OH) is a common contaminant in wastewater. In certain concentrations, phenol can inhibit the activity of microorganisms and give adverse effects tohumanhealth, such as liver and kidney damage, perfect heart rate, and lower blood pressure. In this study, phenol was degraded with andwithoutN-doped TiO2under photolysis UV-light (10 Watts, λ = 365 nm) and visible-light (13 watt Philips, lux= 1400, λ = 465-640 nm)irradiation. The reductionof phenol concentrationwas measured by a UV-Vis spectrophotometer at a wavelength 200-400 nm. Some parameters such as catalyst dose, irradiation timesand type of light sources were studied. The XRD and DRS UV-Vis characterization confirmthat the nitrogen modified of titania catalyst potentially actives in visible-light. The N-doped TiO2is able to catalyze and improve the efficiency of phenol degradation in photocatalysissystem. Phenol with initialconcentration 8 mg/L was degraded by 33.89% and 30.51% without catalyst and increased to be 90.8% and 67.80%by additionof 15 mg N-doped TiO2catalyst under UV-light and visible-lightfor 210 minutes photolysis, respectively. From the results,irradiation using UV-light achieveshigherefficiency than visible-lightonphenol degradation.]]>
<![CDATA[Penentuan Jenis dan Konsentrasi Pelarut untuk Isolasi Zat Warna Kulit Buah Manggis (Garcinia mangostana L) ]]>
<![CDATA[Amin Fatoni]]>;
<![CDATA[Mando Hastuti]]>;
<![CDATA[Dwi Agustina V]]>;
<![CDATA[Suwandri Suwandri]]>
<![CDATA[ Molekul Vol 3, No 1 (2008) ]]>
Publisher : <![CDATA[Universitas Jenderal Soedirman ]]>
Show Abstract
|
Download Original
|
Original Source
|
Check in Google Scholar
|
Full PDF (268.206 KB)
|
DOI: 10.20884/1.jm.2008.3.1.45
<![CDATA[Natural pigment recently have interest to explore to reduce synthetic chemical effect for organism and environment. Mangostine (Garcinia mangostana L) is one of tropical fruit that have peel strong pigment, thus potent as new natural pigmen. Solvents including water, ethanol and methanol applied to extract mangostine peel pigment. The best solvent determined by measuring pigment filtrate using spectrophotometer. The highest absorbance data indicated the best solvent, i.e. more extract yielded by this solvent. The optimum concentration of the solvent for best extraction also investigated with the same procedure above, and finally the natural pigment obtained identified using paper chromatography. The best solvent investigated for extraction was ethanol at concentration 70%. The pigment extracted from mangostine peel proposed as pellargonidine 3-glycoside group of anthocyanin]]>
<![CDATA[Bacterial Cellulose From Rice Waste Water With Addition Chitosan, Glycerol, And Silver Nanoparticle ]]>
<![CDATA[Eli Rohaeti]]>;
<![CDATA[Endang WLFX]]>;
<![CDATA[Anna Rakhmawati]]>
<![CDATA[ Molekul Vol 11, No 1 (2016) ]]>
Publisher : <![CDATA[Universitas Jenderal Soedirman ]]>
Show Abstract
|
Download Original
|
Original Source
|
Check in Google Scholar
|
Full PDF (1210.44 KB)
|
DOI: 10.20884/1.jm.2016.11.1.190
<![CDATA[This study aimed to prepare silver nanoparticles chemically, deposite silver nanoparticles on bacterial cellulose-chitosan-glycerol composite based rice waste water, as well as test the antibacterial activity of bacterial cellulose and its composite. Preparation of silver nanoparticles was conducted by chemical reduction of silver nitrate solution, as well as trisodium citrate as the reductor. Bacterial cellulose from rice waste water is fermented by the bacteria Acetobacter xylinum for 7 days. The dried bacterial cellulose was composited with chitosan and glycerol by immersion method on 2% of chitosan solution and 0.5% of glycerol solution. UV-Vis spectroscopy is used to determine the formation of silvernanoparticles and Particle Size Analyzer to test the size and particle size distribution. Characterization was conducted to bacterial cellulose and its composite included functional groups by FTIR, the mechanical properties by Tensile Tester, crystallinity by XRD, surface photograph by SEM, and antibacterial test against S. aureus and E. coli by the shake flask turbidimetry method. Silver nanoparticle characterization indicated that silver nanoparticles are formed at a wavelength of 421.80 nm, yellow, diameter particle size of 61.8 nm. SEM images showed that the surface of bacterial cellulose had deposited silver nanoparticles and antibacterial test showed an inhibitory effect of bacterial cellulose, bacterial cellulose-chitosan composite, and bacterial cellulose-chitosan-glycerol composite which are deposited silver nanoparticles against the growth of S. aureus and E. coli bacteria.]]>
<![CDATA[KAJIAN ADSORPSI LINEAR ALKYL BENZENE SULPHONATE (LAS) DENGAN BENTONIT-KITOSAN ]]>
<![CDATA[Miftah Rifai]]>;
<![CDATA[Irwan Nugraha]]>
<![CDATA[ Molekul Vol 8, No 2 (2013) ]]>
Publisher : <![CDATA[Universitas Jenderal Soedirman ]]>
Show Abstract
|
Download Original
|
Original Source
|
Check in Google Scholar
|
Full PDF (391.468 KB)
|
DOI: 10.20884/1.jm.2013.8.2.141
<![CDATA[Deterjen pada umumnya tersusun atas surfaktan anionik seperti LAS (Linear alkyl Benzene sulphonate). pada percobaan ini LAS dapat menyerap sinar pada daerahuv dengan panjang gelombang maksimumnya adalah 223,5 nm. LAS dalam perairan dapat menimbulkan potensi masalah pencemaran.Tujuan dari penelitian ini adalah sebagai salah satu alternatif penanganan masalah pencemaran limbah domestik dengan cara menguji kinerja bentonit alam dan bentonit termodifikasi kitosan dalam mengadsorpsi LAS. Untuk mengetahui bahwa kitosan telah bereaksi dengan bentonit maka diuji dengan FTIR dan XRD pada bentonit alam dan bentonit-kitosan. Kemudian ditentukan waktu kontak optimum antara LAS dengan bentonit alam dan bentonit-kitosan. Serta penentuan isoterm adsorpsi LAS dengan bentonit alam dan bentonit-kitosan dengan cara membuat variasi konsentrasi larutan LAS. Uji kinerja bentonit alam dan bentonit-kitosan dalam mengadsorpsi LAS dilakukan dengan menggunakan sistem batch. Didapat waktu kontak optimum antara LAS berinteraksi dengan bentonit alam adalah 15 menit dengan kapasitas adsorpsi sebesar 3,265 mg/g. Sedangkan Waktu kontak optimum interaksi LAS dengan bentonit-kitosan terjadi pada waktu 15 menit dengan kapasitas adsorpsi sebesar 1,7mg/g. Dari hasil yang didapat maka dapat terlihat bahwa bentonit alam memiliki kapasitas adsorpsi yang lebih besar dibandingkan bentonit hasil modifikasi dengan kitosan. Interaksi antara bentonit alam dan bentonit–kitosan dengan LAS terjadi secara fisik dengan energi adsorpsi bentonit alam dengan LAS adalah 19,31 KJ/mol dan energi adsorpsi bentonit-kitosan dengan LAS adalah 19,60 KJ/mol.]]>
<![CDATA[Quantitative Structure-Property Relationship Analysis Against Critical Micelle Concentration of Sulfonate-Based Surfactant Based on Semiempirical Zindo/1 Calculation ]]>
<![CDATA[Ponco Iswanto]]>;
<![CDATA[Eva Vaulina Yulistia Delsy]]>;
<![CDATA[Ely Setiawan]]>;
<![CDATA[Fiandy Aminullah Putra]]>
<![CDATA[ Molekul Vol 14, No 2 (2019) ]]>
Publisher : <![CDATA[Universitas Jenderal Soedirman ]]>
Show Abstract
|
Download Original
|
Original Source
|
Check in Google Scholar
|
Full PDF (129.009 KB)
|
DOI: 10.20884/1.jm.2019.14.2.467
<![CDATA[Development of anionic surfactant compound isvery important because the anionic surfactant class iswidely used in people's lives. For instance,anionic surfactantsare used as food additives and detergents. The novelcompound of sulfonate-basedsurfactantor proposed compound has predictedthe CriticalMicelle Concentration(CMC) value of experiment. Quantitative Structure-Property Relationship (QSPR)analysisbased on semiempiricalZINDO/1 calculationwas conducted to obtain QSPR equation. Theoretical predictorsor independent variable which have an influence on the value of CMC are used to construct QSPR equation. The theoretical predictors areclassified intopredictor of electronic properties, solubility and steric. A total of 108experimentalCMCbelongs to sulfonate-basedsurfactant are calculated their theoretical predictors and analyzed by multiple linear regression. The QSPR equationwhich is obtainedfromthis study contains theimportant theoretical predictors.They are solubility properties, molecular weight, molecular size and net charge of carbon atomin thepolar partof sulfonate-based surfactant. This QSPR equation couldbe used to predict the CMC value of the novelsulfonate-based surfactant.]]>
<![CDATA[AKTIVITAS ANTIBAKTERI KITOSAN TERHADAP BAKTERI S.aureus ]]>
<![CDATA[Mardiyah Kurniasih]]>;
<![CDATA[Dwi Kartika]]>
<![CDATA[ Molekul Vol 4, No 1 (2009) ]]>
Publisher : <![CDATA[Universitas Jenderal Soedirman ]]>
Show Abstract
|
Download Original
|
Original Source
|
Check in Google Scholar
|
Full PDF (127.248 KB)
|
DOI: 10.20884/1.jm.2009.4.1.56
<![CDATA[Chitosan is the N-deacetylated derivative of chitin. Chitosan is biodegradable, biocompatible and non-toxic. Chitosan is polycationic in acidic media and give antibacterial activity. In this paper, antibacterial activity of chitosan have been studied.Chitosan had been isolated from white shrimp. Antibacterial activity of chitosan solutions was examined against S. aureus The result showed that antimicrobial effect on S. aureus was strengthened as the choitosan concentrate decreased.]]>
<![CDATA[Optimizing Conditions to Cholesterol Adsorbed with Carboxymethyl Chitosan ]]>
<![CDATA[Mardiyah Kurniasih]]>;
<![CDATA[Dwi Kartika]]>;
<![CDATA[Riyanti Riyanti]]>
<![CDATA[ Molekul Vol 11, No 1 (2016) ]]>
Publisher : <![CDATA[Universitas Jenderal Soedirman ]]>
Show Abstract
|
Download Original
|
Original Source
|
Check in Google Scholar
|
Full PDF (605.921 KB)
|
DOI: 10.20884/1.jm.2016.11.1.200
<![CDATA[A research on optimizing conditions to cholesterol adsorbed have been performed. Optimization was performed by varying: contact time, adsorbent weight and temperature of the system's. A full factorial experimental design was used in this study. Characterization performed on the synthesized chitosan and carboxymethyl chitosan including FTIR, water content, ash content, solubility, porosity, and swelling effect. The results showed that carboxymethyl chitosan able to adsorb cholesterol under conditions optimal adsorbent with cholesterol ratio (1:200) with a contact time of 90 minutes at temperature of 40 °C. Meanwhile, at a temperature of 55 °C carboxymethyl chitosan capable of adsorb cholesterol under conditions optimal adsorbent with cholesterol ratio (1:300) with a contact time of 30 minutes. Chitosan and carboxymethyl chitosan synthesized has a water content of 7.4 and 10.2%, ash content of 0.14 and 2.29%, solubility in distilled water at 1.10-5and 1.98.10-3%, solubility in acetic acid 0.02 and 0.04%, porosity at 88.3% and 88.8%, and swelling at 163.13 and 182.98%.]]>
<![CDATA[PEMBUATAN DAN UJI KEMAMPUAN MEMBRAN KITOSAN SEBAGAI MEMBRAN ULTRAFILTRASI UNTUK PEMISAHAN ZAT WARNA RHODAMIN B ]]>
<![CDATA[Nita Kusumawati]]>;
<![CDATA[Septiana Tania]]>
<![CDATA[ Molekul Vol 7, No 1 (2012) ]]>
Publisher : <![CDATA[Universitas Jenderal Soedirman ]]>
Show Abstract
|
Download Original
|
Original Source
|
Check in Google Scholar
|
Full PDF (552.803 KB)
|
DOI: 10.20884/1.jm.2012.7.1.105
<![CDATA[Telah dilakukan penelitian tentang pembuatan membran kitosan dan aplikasinya dalam pemisahan zat warna Rhodamin B. Tujuan penelitian ini adalah untuk mengetahui karakteristik fisik serta kinerja membran kitosan yang dihasilkan dalam memisahkan zat warna Rhodamin B dengan variasi konsentrasi kitosan dan tekanan operasional. Penelitian ini diawali dengan pembuatan membran dengan variasi konsentrasi kitosan, yaitu 1-5%. Membran kitosan dibuat dengan mencampurkan kitosan dalam asam asetat 1% kemudian dicetak pada cawan petri. Uji karakteristik fisik membran meliputi, kekuatan tarik dan regangan membran menggunakan Autograph, dan morfologi serta ukuran pori membran menggunakan Scanning Eletron Microscopy (SEM). Kinerja membran meliputi nilai fluks dan rejeksi, diketahui dari pengukuran menggunakan alat uji membran “dead-end” dan UV-Visible Genesys 10. Hasil penelitian menunjukkan bahwa membran kitosan yang dihasilkan masuk dalam rentang membran ultrafiltrasi. Membran memiliki daya tegang dan regang yang tinggi dengan bertambahnya konsentrasi kitosan. Nilai tegangan (Load) yang diperoleh sebesar 0,1531–2,8571 kgf dan nilai regangan (Stroke) sebesar 2,86-5,48%. Semakin besar konsentrasi kitosan dalam membran akan menghasilkan fluks yang kecil. Nilai fluks terbaik dihasilkan oleh membran kitosan 1% pada tekanan 5 kg/cm2 yakni sebesar 38,372 L/m2 jam. Sedangkan nilai koefisien rejeksi tertinggi dihasilkan oleh membran kitosan 3% pada tekanan 1 kg/cm2 yakni sebesar 88,27%.]]>
<![CDATA[An Electrochemical Immunosensor for the Detection of B-Type Natriuretic Peptide (BNP) Based on Sandwich ELISA Using Screen Printed Carbon Electrodes ]]>
<![CDATA[Yeni Wahyuni Hartati]]>;
<![CDATA[Muhammad Hilman Daniswara]]>;
<![CDATA[Ratna Nurmalasari]]>;
<![CDATA[Shabarni Gaffar]]>;
<![CDATA[Toto Subroto]]>
<![CDATA[ Molekul Vol 13, No 1 (2018) ]]>
Publisher : <![CDATA[Universitas Jenderal Soedirman ]]>
Show Abstract
|
Download Original
|
Original Source
|
Check in Google Scholar
|
Full PDF (448.537 KB)
|
DOI: 10.20884/1.jm.2018.13.1.379
<![CDATA[B-type natriuretic peptide (BNP) is a 32-amino acid polypeptide, a cardiac neuro hormone that specifically secreted from heart ventricle as a response towards the increase of volume and pressure in the heart. The determination of BNP concentration in patients blood is one of the method used to diagnose heart failure. An electrochemical immunosensor modified with the streptavidin/biotin system on screen printed carbon electrodes for the detection of the BNP antigen was developed in this study. Monoclonal anti-BNP capture antibody was immobilized on streptavidin-modified SPCEs to give a well oriented of antibody. Furthermore, a biotinylated anti-BNP that conjugated with horseradish peroxidase (HRP) was used as secondary antibody. The electrochemical signal produced by redox activity of substrate 3,3,5,5'-tetramethybezidine dihydrochloride (TMB/H2O2) was measured by differential pulse voltammetry. The BNP immunosensor showed a linear response between 1.0×10-2 and 1.0×102 ng/mL, and the limit of detection was 3.3 ng/mL. BNP immunosensor is a promising technology for the rapid and convenient detection of heart failure.]]>
<![CDATA[FRAKSINASI EKSTRAK METANOL KULIT BATANG Rhizophora mucronata DAN UJI DAYA HAMBATNYA TERHADAP BAKTERI Escherichia coli ]]>
<![CDATA[Dian Riana Ningsih]]>;
<![CDATA[Warsinah Warsinah]]>;
<![CDATA[Suwandri Suwandri]]>
<![CDATA[ Molekul Vol 1, No 1 (2006) ]]>
Publisher : <![CDATA[Universitas Jenderal Soedirman ]]>
Show Abstract
|
Download Original
|
Original Source
|
Check in Google Scholar
|
Full PDF (122.293 KB)
|
DOI: 10.20884/1.jm.2006.1.1.20
<![CDATA[Rhizhophora mucronata is commonly found mangrove plant due to it’s wide distribution. The bark of this plant used for traditional medicine as slimming, antidiarrhea , anticonstipation. The chemical compounds of R. mucronata are tannins, alcaloide, flavanoids and saponin. In order to find out the effect of chemical activity of this plant, a research entitled Fractionation Metanol Extracts Bark of R. Mucronata and Inhibiting Capacity Assay againstEscherichia coli Bacteria has been carried out.The bark of R. mucronata was extracted by soxhlet with methanol solvent. Than methanol extract was fractionated with developing solvent kloroform : metanol (1:9) and producing five fractions that gave positive result on test for alcaloide compounds. The result of infrared spectroscopy that fraction 1-5 also contains of alcaloide. All fractions from coulomn chromatography tested on E. coli with dilution method which gave result that these fractions inhibit the growth of E. coli.]]>
