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JFIOnline
ISSN : 14121107     EISSN : 2355696X     DOI : -
Core Subject : Health,
Jurnal Farmasi Indonesia yang diterbitkan oleh Pengurus Pusat Ikatan Apoteker Indonesia. Isi website memuat seluruh jurnal yang telah diterbitkan mencakup semua aspek dalam ilmu pengetahuan dan teknologi kefarmasian antara lain farmakologi, farmakognosi, fitokimia,farmasetika, kimia farmasi, biologi molekuler, bioteknologi, farmasi klinik,farmasi komunitas, farmasi pendidikan, dan lain-lain.
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Articles 28 Documents
Search results for , issue "Vol 9, No 1 (2017)" : 28 Documents clear
PRODUKSI ASAM GALAT DARI LIMBAH BUAH LOKAL DI PULAU LOMBOK SECARA ENZIMATIS JUNAIDI, EKA; ANWAR, YUNITA ARIAN SANI
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol 9, No 1 (2017): Punica Granatum
Publisher : Indonesian Research Gateway

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Abstract

ABSTRAK : Asam galat merupakan salah satu bahan obat yang belum dapat diproduksi dalam jumlah besar di dalam negeri. Senyawa ini berperan sebagai bahan sintetis antioksidan dan antibakteri. Penelitian ini bertujuan untuk menghasilkan asam galat menggunakan limbah buah lokal di Pulau Lombok secara enzimatis. Terdapat 3 jenis limbah buah lokal yang digunakan yaitu kulit buah juwet, kulit buah kepundung dan kulit buah manggis. Hasil penelitian menunjukkan enzim yang digunakan adalah tanase dengan aktivitas sebesar 57,827 U/mg. Asam galat tertinggi diperoleh pada konsentrasi enzim tanase sebesar 1% dan waktu reaksi sebesar 60 menit untuk kulit buah kepundung sedangkan kulit buah manggis dan kulit buah juwet menghasilkan asam galat tertinggi pada konsentrasi enzim tanase sebesar 1,2% dengan waktu reaksi yang sama. Jenis kulit buah lokal yang paling baik sebagai penghasil asam galat adalah kulit buah kepundung.
ANALISIS FAKTOR YANG MEMPENGARUHI KEPATUHAN PENGAMBILAN OBAT PESERTA PROGRAM RUJUK BALIK DI BANDAR LAMPUNG Efayanti, Dwi
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol 9, No 1 (2017): Punica Granatum
Publisher : Indonesian Research Gateway

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Abstract

ABSTRACT : Program (Program Rujuk Balik = PRB) through a health care program for the participants of the National Health Insurance with chronic diseases. Barriers to success of therapeutic treatment for patients with chronic diseases is non-adherence  related to the patient's treatment regimen. Taking medication adherence for patients with chronic illness is the first adherence can be assessed on how a person decides to get medicines for themselves. Analyzing factors affecting medication adherence taking participants PRB is important, cause non-adherence adverse effects appear in the treatment.  Participants adherence taking the drug on a PRB can be obtained from the data prescription claims to calculate the medication possession ratio (MPR), which MPR ≥ 80% declared adherence. Data obtained from  prescription claim by participants PRB for  September 2015 until December 2015 in Bandar Lampung. Sample case study 82 people with diabetes. The calculation result MPR explains that 62.2% of respondents declared adherence taking medication, while 37.8% of respondents declared non-adherence. The results of the  logistic regression analysis, stating that there are influences together of factors respondents' knowledge, respondents belief, attitudes of personnel pharmacy services, pharmacy facilities, cost, availability of medication PRB, family support, and accessibility affect to respondent adherence of  taking medication. However, factors that significantly influence medication adherence refer the decision back is knowledge of respondents with sig = 0,028 (sig <0.05), belief of respondents with sig = 0,003 (sig <0.05), and accessibility sig = 0,044 (sig < 0.05) significantly affect to adherence  of taking medication.
KAJIAN KEAMANAN ANTIHIPERTENSI PASIEN GAGAL GINJAL KRONIK LANJUT USIA DI UNIT HEMODIALISA RSUP DR. SARDJITO YOGYAKARTA Setyaningrum, Ndaru; Pramantara, I Dewa Putu
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol 9, No 1 (2017): Punica Granatum
Publisher : Indonesian Research Gateway

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Abstract

ABSTRACT : The growth of elderly population increase fastest among the other age group. The elderly population been related to decrease renal function and other comorbidity as consequence of aging. The aim of this study is to know how about adverse drug reaction (ADR) and potential interaction of antihypertension drug in chronic kidney disease patient. This is a descriptive study about elderly patient with chronic kidney disease on period October 22th 2012 – January 22th 2013. This study use Naranjo scale to evaluate ADR and Tatro Drug Interactions Fact to evaluate potential drug interaction. There were 38 subjects analized, age < 70 years old (24 patients) and ≥ 70 years old (14 patients); gender men (26 patients) and women (12 patients); duration hemodialysis < 8 months (8 patients) and ≥ 8 months (30 patients); comorbidity DM (23 patients) and non DM (15 patients). There were probable ADR 4 events (10,8%) consist of nifedipine (2 events), lisinoprile (1 event) and captoprile (1 event). There were 14 events (37,8%) potential drug interactions consist of minor interaction (12 events) 32,4% and major interaction (2 events) 5,4%. This study show that there were actual probable ADR 10,8% and potential drug interaction 37,8%.  
ANALISIS FAKTOR YANG MEMPENGARUHI KEPATUHAN PENGAMBILAN OBAT PESERTA PROGRAM RUJUK BALIK DI BANDAR LAMPUNG Setyaningrum, Ndaru; Pramantara, I Dewa Putu
Jurnal Farmasi Indonesia Vol 9, No 1 (2017)
Publisher : Jurnal Farmasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (4801.067 KB) | DOI: 10.35617/jfi.v9i1.552

Abstract

ABSTRACT : Program (Program Rujuk Balik = PRB) through a health care program for the participants of the National Health Insurance with chronic diseases. Barriers to success of therapeutic treatment for patients with chronic diseases is non-adherence  related to the patient's treatment regimen. Taking medication adherence for patients with chronic illness is the first adherence can be assessed on how a person decides to get medicines for themselves. Analyzing factors affecting medication adherence taking participants PRB is important, cause non-adherence adverse effects appear in the treatment.  Participants adherence taking the drug on a PRB can be obtained from the data prescription claims to calculate the medication possession ratio (MPR), which MPR � 80% declared adherence. Data obtained from  prescription claim by participants PRB for  September 2015 until December 2015 in Bandar Lampung. Sample case study 82 people with diabetes. The calculation result MPR explains that 62.2% of respondents declared adherence taking medication, while 37.8% of respondents declared non-adherence. The results of the  logistic regression analysis, stating that there are influences together of factors respondents' knowledge, respondents belief, attitudes of personnel pharmacy services, pharmacy facilities, cost, availability of medication PRB, family support, and accessibility affect to respondent adherence of  taking medication. However, factors that significantly influence medication adherence refer the decision back is knowledge of respondents with sig = 0,028 (sig <0.05), belief of respondents with sig = 0,003 (sig <0.05), and accessibility sig = 0,044 (sig < 0.05) significantly affect to adherence  of taking medication.
PRODUKSI ASAM GALAT DARI LIMBAH BUAH LOKAL DI PULAU LOMBOK SECARA ENZIMATIS JUNAIDI, EKA; ANWAR, YUNITA ARIAN SANI
Jurnal Farmasi Indonesia Vol 9, No 1 (2017)
Publisher : Jurnal Farmasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (4476.959 KB) | DOI: 10.35617/jfi.v9i1.559

Abstract

ABSTRAK : Asam galat merupakan salah satu bahan obat yang belum dapat diproduksi dalam jumlah besar di dalam negeri. Senyawa ini berperan sebagai bahan sintetis antioksidan dan antibakteri. Penelitian ini bertujuan untuk menghasilkan asam galat menggunakan limbah buah lokal di Pulau Lombok secara enzimatis. Terdapat 3 jenis limbah buah lokal yang digunakan yaitu kulit buah juwet, kulit buah kepundung dan kulit buah manggis. Hasil penelitian menunjukkan enzim yang digunakan adalah tanase dengan aktivitas sebesar 57,827 U/mg. Asam galat tertinggi diperoleh pada konsentrasi enzim tanase sebesar 1% dan waktu reaksi sebesar 60 menit untuk kulit buah kepundung sedangkan kulit buah manggis dan kulit buah juwet menghasilkan asam galat tertinggi pada konsentrasi enzim tanase sebesar 1,2% dengan waktu reaksi yang sama. Jenis kulit buah lokal yang paling baik sebagai penghasil asam galat adalah kulit buah kepundung.
Uji Aktivitas Antioksidan Kombinasi Daun Kopi Arabika (Coffea arabica) dan Daun Pandan (Pandanus amaryllifolius) dengan Metode DPPH Retnaningtyas, Yuni; Hamzah, Muhammad Hafidi; Kristiningrum, Nia
Jurnal Farmasi Indonesia Vol 9, No 1 (2017)
Publisher : Jurnal Farmasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (5577.823 KB) | DOI: 10.35617/jfi.v9i1.553

Abstract

ABSTRACT : Antioxidants are nutrient that can prevent the oxidative damage in the body. Arabica coffee and pandan is most common species of plant found in Indonesia. Arabica coffee and pandan known as plants with antioxidant activity. This study aimed to determine and compare antioxidant activity of water and ether fraction from methanolic extract of Arabica coffee leaves, pandan leaves and both combination by DPPH method. Vitamin C was used as positive control. The result show that Arabica coffee leaves have antioxidant activity better than pandan leaves and also gives big donation of antioxidant activity in their combinations. Statistical analysis showed that antioxidant activity from all sample were significanly different (p<0,05).
Uji Aktivitas Antioksidan Kombinasi Daun Kopi Arabika (Coffea arabica) dan Daun Pandan (Pandanus amaryllifolius) dengan Metode DPPH Retnaningtyas, Yuni; Hamzah, Muhammad Hafidi; Kristiningrum, Nia
Jurnal Farmasi Indonesia Vol 9, No 1 (2017)
Publisher : Jurnal Farmasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (984.415 KB) | DOI: 10.35617/jfi.v9i1.565

Abstract

ABSTRACT : Antioxidants are nutrient that can prevent the oxidative damage in the body. Arabica coffee and pandan is most common species of plant found in Indonesia. Arabica coffee and pandan known as plants with antioxidant activity. This study aimed to determine and compare antioxidant activity of water and ether fraction from methanolic extract of Arabica coffee leaves, pandan leaves and both combination by DPPH method. Vitamin C was used as positive control. The result show that Arabica coffee leaves have antioxidant activity better than pandan leaves and also gives big donation of antioxidant activity in their combinations. Statistical analysis showed that antioxidant activity from all sample were significanly different (p<0,05).  
ANALISIS FAKTOR YANG MEMPENGARUHI KEPATUHAN PENGAMBILAN OBAT PESERTA PROGRAM RUJUK BALIK DI BANDAR LAMPUNG Efayanti, Dwi
Jurnal Farmasi Indonesia Vol 9, No 1 (2017)
Publisher : Jurnal Farmasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (746.226 KB) | DOI: 10.35617/jfi.v9i1.564

Abstract

ABSTRACT : Program (Program Rujuk Balik = PRB) through a health care program for the participants of the National Health Insurance with chronic diseases. Barriers to success of therapeutic treatment for patients with chronic diseases is non-adherence  related to the patient's treatment regimen. Taking medication adherence for patients with chronic illness is the first adherence can be assessed on how a person decides to get medicines for themselves. Analyzing factors affecting medication adherence taking participants PRB is important, cause non-adherence adverse effects appear in the treatment.  Participants adherence taking the drug on a PRB can be obtained from the data prescription claims to calculate the medication possession ratio (MPR), which MPR � 80% declared adherence. Data obtained from  prescription claim by participants PRB for  September 2015 until December 2015 in Bandar Lampung. Sample case study 82 people with diabetes. The calculation result MPR explains that 62.2% of respondents declared adherence taking medication, while 37.8% of respondents declared non-adherence. The results of the  logistic regression analysis, stating that there are influences together of factors respondents' knowledge, respondents belief, attitudes of personnel pharmacy services, pharmacy facilities, cost, availability of medication PRB, family support, and accessibility affect to respondent adherence of  taking medication. However, factors that significantly influence medication adherence refer the decision back is knowledge of respondents with sig = 0,028 (sig <0.05), belief of respondents with sig = 0,003 (sig <0.05), and accessibility sig = 0,044 (sig < 0.05) significantly affect to adherence  of taking medication.
AKTIVITAS ANTIJERAWAT DARI LOTION LENDIR BEKICOT (ACHATINA FULICA) Ristiawati, Nita; Kristanty, Ruth Elenora
Jurnal Farmasi Indonesia Vol 9, No 1 (2017)
Publisher : Jurnal Farmasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (5521.153 KB) | DOI: 10.35617/jfi.v9i1.554

Abstract

ABSTRAK : Lendir bekicot (Achatina fulica) dalam bentuk lotion telah diuji secara ilmiah aktivitasnya terhadap bakteri penyebab infeksi jerawat. Penelitian bertujuan menghasilkan formula lotion lendir bekicot yang bisa mengobati jerawat. Metode pengujian antibakteri menggunakan turbidimetri. Evaluasi sediaan yang dilakukan meliputi pengamatan organoleptik dan pH, ujidaya sebar dan uji daya lekat. Berdasarkan hasil pengujian yang telah dilakukan, lendir bekicot dan lotion lendir bekicot memiliki aktivitas antibakteri terhadap Propionibacterium acnes. Lotion lendir bekicot yang menghasilkan efek anti jerawat paling baik adalah yang mengandung konsentrasi lendir 16%. Sediaan lotion memiliki karakteristik, daya sebar, dan daya rekat yang baik. Bentuk sediaan stabil dalam penyimpanan suhu kamar selama lima minggu.
Tinjauan Implementasi Penilaian Risiko Terintegrasi Terhadap Manajemen Rantai Pasok pada Industri Farmasi Dermawan, Doni; Bahtiar, Rio
Jurnal Farmasi Indonesia Vol 9, No 1 (2017)
Publisher : Jurnal Farmasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (5654.253 KB) | DOI: 10.35617/jfi.v9i1.546

Abstract

ABSTRAK : Akses akan obat sebagai salah satu hak manusia merupakan salah satu tujuan utama diselenggarakannya sistem pelayanan kesehatan. Rantai pasok (supply chain) produk farmasi harus dapat menyediakan obat dengan kuantitas yang memadai dan kualitas yang memenuhi pesyaratan. Manajemen risiko rantai pasok merupakan bagian penting dan tak terpisahkan dari manajemen rantai pasok untuk mencapai tujuan implementasinya. Tinjauan literatur ini sebagai langkah pertama dari manajemen risiko pada rantai pasok produk farmasi yang bertujuan untuk mengidentifikasi semua risiko yang dapat mengancam akses terhadap obat akibat aspek-aspek yang berperan sebagai tinjauan. Penilaian berfokuspada risiko kualifikasi pemasok dan rantai pasok, risiko finansial, risiko organisasi perusahaan, risiko logistik, isu pasar, dan regulasi. Hasil pengolahan data menunjukkan bahwakualifikasi pemasok adalah masalah paling penting yakni sebesar 45 % dari keseluruhan risiko. Oleh karena itu, perlu adanya pula implementasi yang sifatnya integratif dan komprehensif terhadap penilain risiko-risiko pada rantai pasok produk farmasi secara konsisten dan berkelanjutan.

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