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Oto Rhino Laryngologica Indonesiana
Published by Perhimpunan Dokter Spesialis Telinga Hidung dan Tenggorok Bedah Kepala Leher Indonesia
ISSN : 02163667     EISSN : 25983970     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology
Journal Othorhinolaryngologica Indonesiana is a peer-reviewed and open access journal that focuses on promoting otorhinolaryngology-head and neck surgery that publishes research reports, case reports, and literature reviews, to increase knowledge and updating diagnostics procedurs on otorhinolaryngology-head and neck surgery.
Arjuna Subject : -
Articles 493 Documents
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A survey of Indonesian otolaryngologist behavior in medical service during the CoVid-19 pandemic Indra Zachreini; Jenny Bashiruddin; Susyana Tamin; Harim Priyono; Ika Dewi Mayangsari; Respati Ranakusuma; Natasha Supartono; Fikri Mirza Putranto; Dewo Aksoro; Selfiyanti Bimantara; Yussy Afriana Dewi; Kote Noordhianta; Bintang Napitupulu; Sagung Rai Indrasari; Nyilo Purnami; Tengku Siti Hajar Haryuna; Juliandi Harahap; Eka Savitri; Tjandra Manukbua
Oto Rhino Laryngologica Indonesiana Vol. 51 No. 1 (2021): Volume 51, No. 1 January - June 2021
Publisher : PERHATI-KL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32637/orli.v51i1.444

Abstract

Background: World Health Organization (WHO) announced a newly discovered virus that first identified in Wuhan, China on December 2019, namely SARS-CoV-2 as the cause of corona virus disease (COVID-19) which had become global pandemic. Doctors as medical practitioners are categorized as vulnerable group to be infected by corona virus, and many otorhinolaryngologists had been infected and even died in performing medical services. Among the causative factors why otorhinolaryngologists could get infected by corona virus is their behavior. Purpose: To assess the behavioral level of otorhinolaryngologists in medical services during Covid-19 pandemic. Method: Descriptive study with a cross sectional design. Research samples were otorhinolaryngologists in Indonesia who met the inclusions criteria. The samples were selected by consecutive sampling method, and obtained 1299 subjects. Behavioral level was assessed from 3 aspects: knowledge, attitude, and practice, which comprised of 12 questions. Result: It was found that 461 respondents had a good behavioral level (35.5%), 677 respondents had moderate levels (52.1%) and 161 respondents had low level (12.4%). There was a statistically significant correlation between knowledge with behavioral level, attitude with behavioral level, and practice with behavioral level (p=0.001). Conclusion: The study of behavioral level of otorhinolaryngologists in medical service during Covid-19 pandemic obtained the highest number was moderate level 677 respondents (57.2%), and there was a statistically significant correlations between the variable of knowledge with behavioral level, the variable of attitude with behavioral level, and the variable of practice with behavioral level (p=0.001).ABSTRAK Latar belakang: Organisasi kesehatan dunia (WHO) mengumumkan virus baru yang pertama kali muncul di Wuhan China, pada Desember 2019, yaitu SARS-CoV-2 sebagai penyebab corona virus disease 19 (Covid 19) dan menyatakan sebagai pandemi. Dokter sebagai tenaga kesehatan merupakan kelompok yang rentan terinfeksi virus corona dan berdasarkan laporan, sudah banyak dokter Telinga Hidung Tenggorok - Bedah Kepala Leher (THT-KL) yang terinfeksi bahkan meninggal dunia dalam pelayanan medis. Salah satu faktor penyebab dokter THT-KL terinfeksi oleh virus corona adalah tingkat perilaku dokter THT-KL. Tujuan: Mengetahui tingkat perilaku dokter THT-KL dalam melakukan pelayanan medis saat pandemi Covid 19. Metode: Penelitian deskriptif dengan rancangan studi potong lintang. Sampel penelitian adalah dokter THT-KL di Indonesia yang memenuhi kriteria inklusi. Teknik pengambilan sampel secara berurutan, dan mendapatkan 1299 sampel. Tingkat perilaku dinilai dari 3 aspek yaitu dimulai dari pengetahuan, sikap dan tindakan yang terdiri dari 12 pertanyaan. Hasil: Didapatkan tingkat perilaku responden dokter THT-KL dalam pelayanan medis pada pandemi Covid 19, tingkat perilaku baik sebanyak 461 responden (35,4%), tingkat sedang 677 responden (52,1%), dan tingkat kurang 161 responden (12.4%). Terdapat hubungan yang signifikan antara pengetahuan dan tingkat perilaku, sikap dengan tingkat perilaku dan tindakan dengan sikap perilaku (p=0,001). Kesimpulan: Didapatkan tingkat perilaku dokter THT-KL dalam pelayanan medis pada pandemi covid 19, terbanyak adalah tingkat perilaku sedang sebanyak 677 responden (57,2%), dan terdapat hubungan yang bermakna antara variabel pengetahuan dengan tingkat perilaku, variabel sikap dengan tingkat perilaku dan variabel tindakan dengan tingkat perilaku dokter THT-KL dalam pelayanan medis pada pandemi Covid 19, dimana nilai p = 0,001. Kata kunci: perilaku, dokter THT-KL, pandemic, Covid-19
Sensorineural hearing loss in Bartter syndrome Semiramis Zizlavsky; Fadilah -; Ronny Soewento; Tri Juda Airlangga
Oto Rhino Laryngologica Indonesiana Vol. 51 No. 1 (2021): Volume 51, No. 1 January - June 2021
Publisher : PERHATI-KL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32637/orli.v51i1.445

Abstract

Background: Bartter syndrome is a rare inherited case characterized by autosomal recessive and has few different types. Diagnosis is established by laboratory findings, namely hypokalemic metabolic alkalosis, and normotensive. Hearing loss indicates Bartter syndrome type IV. Purpose: To report a case of Bartter syndrome with delayed speech. Case report: A seven years old girl with delayed speech and recurrent hypokalemia was referred to the Otolaryngology Head and Neck Surgery Department, Dr. Cipto Mangunkusumo Hospital, in order to evaluate the hearing level and treatment needed. Based on the Otoacoustic Emission (OAE), Brainstem Evoked Response Audiometry (BERA), and Auditory State Steady Response (ASSR), the diagnosis was profound bilateral sensorineural hearing loss and proceeded with hearing aid and also speech occupational therapy. Clinical question: Is there a relationship between Bartter syndrome and the incidence of hearing loss? Review method: Literature review through PubMed, Cochrane, and EBSCO, using keywords such as the impacts of Bartter syndrome on hearing loss, and sensorineural hearing loss in Bartter syndrome case. Result: Following screening of double publication and based on clinical questions over the past five years, only one relevant literature was found. Conclusion: Audiological assessment should be done in all Bartter syndrome’s cases. Early intervention and timely audiological rehabilitation could improve the quality of life of such children.ABSTRAK Latar belakang: Sindrom Bartter merupakan kasus jarang, yang diturunkan secara autosomal resesif dan terdiri atas beberapa tipe. Diagnosis ditegakkan berdasarkan temuan laboratorium yaitu hipokalemi, alkalosis metabolik dan tekanan darah normal. Adanya gangguan pendengaran merupakan sindrom Bartter tipe IV. Tujuan: melaporkan kasus Sindrom Bartter dengan keterlambatan bicara. Kasus: Dilaporkan satu kasus anak perempuan berusia tujuh tahun dengan gangguan bicara dan terdapat riwayat hipokalemia berulang yang dirujuk ke Departemen Telinga Hidung Tenggorok-Bedah Kepala Leher, Rumah Sakit Cipto Mangunkusumo untuk menilai ambang dengar serta tatalaksana selanjutnya. Berdasarkan hasil pemeriksaan Otoacoustic Emission (OAE), Brainstem Evoked Response Audiometry (BERA) dan Auditory State Steady Response (ASSR) ditemukan tuli sensorineural sangat berat bilateral yang kemudian ditatalaksana dengan pemakaian Alat Bantu Dengar dan terapi wicara dan okupasi. Pertanyaan klinis: Apakah ada hubungan antara sindroma Bartter dengan insidens gangguan pendengaran? Telaah literatur: Pencarian literatur melalui, PubMed, Cochrane dan EBSCO dengan kata kunci hubungan gangguan pendengaran pada sindrom Bartter, gangguan pendengaran sensorineural pada sindrom Bartter. Hasil: Setelah dilakukan skrining yakni publikasi ganda dan sesuai pertanyaan klinis dari lima tahun terakhir hanya didapatkan satu literatur yang relevan. Kesimpulan: Pemeriksaan pendengaran harus dilakukan pada kasus dengan sindrom Bartter. Intervensi dini dan rehabilitasi audiologi yang tepat waktu dapat meningkatkan kualitas hidup anak dengan sindrom Bartter.Kata kunci: sindroma Bartter, tuli sensorineural.
Correlation between score for allergic rhinitis and quality of life in chronic rhinitis patients Asti Widuri; Tri Wahyuliati; Winda Retno Ningrum
Oto Rhino Laryngologica Indonesiana Vol. 51 No. 2 (2021): VOLUME 51, NO. 2 JULY - DECEMBER 2021
Publisher : PERHATI-KL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32637/orli.v51i2.446

Abstract

ABSTRACTBackground: Allergic rhinitis is a chronic inflammatory condition of the nasal mucosa that occurs as an Imunoglobulin E (IgE) mediated reaction after provocation of allergen. The prevalence of rhinitis in Indonesia reaches 12.4% and still rising. Chronic rhinitis can affect the quality of life, especially daily activities and sleep disturbances. Purpose: This study aimed to determine the correlation between the Score for Allergic Rhinitis (SFAR) and the patient’s quality of life (QOL) using allergic rhinitis mobile phone application. Method: This was an observational analytic research using cross sectional method. The number of samples was 46 with predetermined inclusion and exclusion criteria. The research instrument used was a mobile phone application of SFAR and for quality of life was Visual Analog Scales (VAS) questionnaire. Data analysis was using Shapiro-Wilk for normality test and contingency coefficient test to determine the correlation between variables. Result: The result showed that there was a significant correlation between the Score for Allergic Rhinitis and the quality of life in chronic rhinitis sufferers (p = 0.000). The correlation had uni-direction and moderate strength (r = 0.567). There were 52.17% respondents who stated that rhinitis complaints would be reduced after using nasal drugs/sprays. And for the VAS parameter, the highest number given was 0 in 45.65% respondents, which meant that they did not feel any discomfort. Conclusion: There was a significant correlation between SFAR and quality of life AR sufferers with moderate strength and uni-direction.Keywords: Score for Allergic Rhinitis, quality of life, rhinitis, mobile applicationABSTRAKLatar belakang: Rinitis alergi adalah kondisi inflamasi kronis pada mukosa hidung sebagai reaksi yang dimediasi Imunoglobulin E (IgE) setelah provokasi alergen. Prevalensi rinitis di Indonesia mencapai 12,4 % dan akan terus meningkat. Rinitis kronik dapat memengaruhi kualitas hidup terutama aktivitas sehari-hari dan gangguan tidur. Tujuan: Penelitian ini bertujuan untuk mengetahui korelasi Score for Allergic Rhinitis (SFAR) dengan kualitas hidup penderita menggunakan aplikasi rinitis alergi pada telepon genggam. Metode: Penelitian ini berupa analitik observasional dengan desain cross sectional. Sampel yang digunakan sebanyak 46 responden dengan kriteria inklusi dan eksklusi yang sudah ditentukan. Instrumen penelitian menggunakan aplikasi telepon genggam berisi kuisioner SFAR dan kualitas hidup dengan Visual Analog Scales (VAS). Analisis data menggunakan Shapiro-Wilk untuk uji normalitas dan uji koefisien kontingensi untuk mengetahui korelasi antar variabel. Hasil: Didapatkan hasil berupa hubungan korelasi yang bermakna antara skor SFAR dengan kualitas hidup penderita rinitis kronik (p=0,000). Hubungan korelasi tersebut memiliki satu arah dan kekuatan yang sedang (r=0,567). Diperoleh pernyataan dari 52,17% responden bahwa keluhan rinitis akan berkurang setelah minum obat/menggunakan semprot hidung. Untuk parameter VAS didapatkan hasil bahwa angka terbanyak yang diberikan adalah 0 pada 45,65% responden, yang berarti tidak merasakan ketidaknyamanan. Kesimpulan: Terdapat korelasi bermakna antara SFAR dan kualitas hidup penderita AR dengan kekuatan hubungan sedang dan satu arah.Kata kunci: Score for Allergic Rhinitis, kualitas hidup, rinitis, aplikasi telepon genggam
Fat graft augmentation rhinoplasty compared to costal cartilage graft in saddle nose panfacial fractures Dini Widiarni Widodo; Satria Dipo Putra Asmoro; Raden Ayu Anatriera
Oto Rhino Laryngologica Indonesiana Vol. 51 No. 2 (2021): VOLUME 51, NO. 2 JULY - DECEMBER 2021
Publisher : PERHATI-KL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32637/orli.v51i2.449

Abstract

ABSTRACTBackground: Panfacial fracture can cause nasal function and esthetics alterations, one of which is saddle nose deformity. Post-traumatic saddle nose could be treated with augmentation rhinoplasty to correct the nasal structure and function. It can use autologous material such as fat graft and cartilage graft. Purpose: To report the effect of fat graft augmentation rhinoplasty compared to costal cartilage graft on patients’ satisfaction of saddle nose panfacial fracture cases. Case report: Reporting two cases of panfacial fracture with saddle nose. The first case, a 22-years-old female with multiple facial fractures underwent plate and screw fixation and nasal fracture close reduction followed by augmentation rhinoplasty using fat graft. The second case was a 23-years-old male diagnosed as blow-out fracture treated with internal fixation and costal cartilage augmentation rhinoplasty. Clinical question: Does fat graft augmentation rhinoplasty result in a better satisfaction level than costal cartilage graft in panfacial fracture with saddle nose cases. Review method: Evidence-based literature searching was performed through Pubmed, Scopus and Proquest databases to evaluate the effect of rhinoplasty augmentation using fat graft compared to costal cartilage on patient satisfaction level. Result: One study showed patient’s high satisfaction level after fat graft augmentation procedure. Another study showed that satisfaction rates were also high in cartilage graft augmentation patients. Conclusion: The advantages of using fat graft augmentation are the more natural esthetic outcome, easy to perform and low morbidity. Rhinoplasty Outcome Evaluation (ROE) questionnaire could be used to evaluate the outcome of augmentation rhinoplasty with high sensitivity and specificity.Keywords: saddle nose, panfacial fracture, fat graft augmentation, costal cartilage graft, ROEABSTRAKLatar belakang: Fraktur panfasial dapat mengakibatkan perubahan struktur wajah disertai kelainan fungsi dan estetika hidung, salah satunya deformitas saddle nose. Saddle nose pasca trauma wajah dapat ditatalaksana dengan rinoplasti augmentasi untuk memperbaiki struktur dan fungsi hidung. Rinoplasti augmentasi dapat menggunakan material tandur autologous misalnya tandur lemak dan kartilago. Tujuan: Melaporkan hasil augmentasi tandur lemak dibandingkan tandur kartilago iga terhadap tingkat kepuasan pasien kasus saddle nose fraktur panfasial. Laporan kasus: Dua kasus fraktur panfasial disertai saddle nose. Kasus pertama, perempuan 22 tahun dengan fraktur wajah multipel, dilakukan fiksasi internal menggunakan plate and screw dan reduksi tertutup fraktur nasal, dilanjutkan rinoplasti augmentasi tandur lemak untuk memperbaiki saddle nose. Kasus kedua, laki-laki 23 tahun dengan fraktur blow-out ditatalaksana dengan fiksasi internal dilanjutkan rinoplasti augmentasi tandur kartilago iga. Pertanyaan klinis: Apakah rinoplasti augmentasi tandur lemak menghasilkan tingkat kepuasaan pasien lebih baik dibandingkan tandur kartilago iga pada kasus saddle nose pada fraktur panfasial? Telaah literatur: Pencarian literatur mengenai pengaruh augmentasi tandur lemak dibanding tandur kartilago iga terhadap tingkat kepuasan pasien fraktur panfasial dalam database Pubmed, Scopus dan Proquest. Hasil: Satu artikel menunjukkan tingkat kepuasan pasien pasca rinoplasti augmentasi tandur lemak yang tinggi dengan tingkat morbiditas rendah. Artikel lain menunjukkan tingkat kepuasan yang juga tinggi pada pasien augmentasi tandur kartilago tanpa komplikasi mayor. Kesimpulan: Keuntungan penggunaan tandur lemak pada rinoplasti adalah terlihat lebih alami, lebih mudah dilakukan dengan morbiditas rendah, akan tetapi dengan tingkat resorpsi tinggi. Kuesioner Rhinoplasty Outcome Evaluation (ROE) dapat menjadi alat untuk menilai outcome dari rinoplasti augmentasi dengan sensitivitas dan spesifitas cukup tinggi.Kata kunci: saddle nose, fraktur panfasial, augmentasi tandur lemak, tandur kartilago iga, ROE
Labyrinthine fistula size as a prognostic factor for postoperative hearing deterioration Ratna Dwi Restuti; Harim Priyono; Ayu Astria Sriyana; Rangga Rayendra Saleh; Eka Dian Safitri
Oto Rhino Laryngologica Indonesiana Vol. 51 No. 2 (2021): VOLUME 51, NO. 2 JULY - DECEMBER 2021
Publisher : PERHATI-KL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32637/orli.v51i2.497

Abstract

ABSTRACTBackground: A labyrinthine fistula is an abnormal opening in the bony capsule of the inner ear, such as cochlea or semi-circular canals that may occur as a complication of chronic suppurative otitis media (CSOM) with cholesteatoma. Purpose: To find out the relation of the size of labyrinthine fistula as a prognostic factor of hearing deterioration after a complete cholesteatoma removal. Case report: Two cases of labyrinthine fistula in CSOM with cholesteatoma, along with preoperative and postoperative audiometry results. Clinical question: Does the labyrinthine fistula size in CSOM with cholesteatoma patients could serve as a prognostic factor in the postoperative hearing outcome? Review method: A structured, evidence-based literature search using Pubmed, Proquest and Cochrane to find studies of labyrinthine fistula as a complication of CSOM. The articles were selected based on eligibility criteria i.e. surgery procedure, labyrinthine fistula measurement, and postoperative evaluation of hearing function. The appraisal of each article used Oxford critical appraisal independently for prognostic study and systematic review. Result: Two studies met the inclusion criteria. One article used cohort retrospective method valid based on appraisal for prognostic studies. The other article used a systematic review method which had low validity. Conclusion: Fistula size is still debatable as a postoperative prognostic factor for hearing deterioration in CSOM with cholesteatoma. Larger sample size and better methods of study are necessary to resolve the clinical question.Keywords: chronic suppurative otitis media (CSOM), cholesteatoma, labyrinthine fistula, fistula sizeABSTRAKLatar belakang: Fistula labirin adalah terbukanya dinding tulang pada koklea atau kanalis semisirkularis yang merupakan suatu komplikasi dari otitis media supuratif kronik (OMSK) tipe bahaya. Tujuan: Untuk menjawab pertanyaan klinis terkait hubungan antara ukuran fistula labirin dengan prognosis penurunan pendengaran pasca operasi pengangkatan kolesteatoma. Laporan kasus: Dua kasus fistula labirin pada penderita OMSK tipe bahaya, disertai dengan hasil pemeriksaan audiometri pendengaran sebelum dan sesudah operasi. Pertanyaan klinis: Apakah ukuran fistula labirin pada kasus OMSK dengan kolesteatoma dapat menjadi faktor penentu prognosis untuk hasil pemeriksaan pendengaran pasca operasi? Telaah literatur: Pencarian literatur berbasis bukti menggunakan Pubmed, Proquest dan Cochrane terkait fistula labirin pada kasus OMSK. Kriteria inklusi studi berdasarkan teknik operasi, ukuran fistula dan evaluasi pendengaran pasca operasi. Metode Oxford critical appraisal digunakan untuk studi prognosis pada satu artikel, dan digunakan systematic review untuk artikel lainnya. Hasil: Dari pencarian literatur terdapat dua artikel yaitu studi kohort retrospektif, dan systematic review yang memenuhi kriteria inklusi. Hasil telaah literatur menunjukan bahwa study kohort retrospektif memiliki validitas cukup baik, sedangkan studi systematic review memiliki validitas yang kurang baik. Kedua artikel ini memiliki hasil yang berbeda dalam hubungan ukuran fistula labirin dengan prognosis penurunan pendengaran pasca operasi. Kesimpulan: Ukuran fistula sebagai faktor prognosis penurunan pendengaran pasca operasi pada kasus OMSK tipe bahaya masih memerlukan penelitian dengan sampel yang lebih banyak, dan metode yang lebih baik untuk dapat menjawab pertanyaan klinis.Kata kunci: otitis media supuratif kronik (OMSK), kolesteatoma, fistula labirin, ukuran fistula
Gangguan pendengaran penderita Tuberkulosis Multidrug Resistant Yulianti, Yulianti; Mahdiani, Sally
Oto Rhino Laryngologica Indonesiana Vol. 45 No. 2 (2015): Volume 45, No. 2 July - December 2015
Publisher : PERHATI-KL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32637/orli.v45i2.112

Abstract

Latar belakang: Tuberkulosis Multidrug Resistant (TB MDR) merupakan penyakit tuberkulosis (TB) yang resisten terhadap isoniazid dan rifampisin, dengan atau tanpa resisten terhadap obat anti- TB lain. Terapi aminoglikosida pada TB MDR berisiko untuk terjadinya gangguan fungsi telinga dan sistem keseimbangan tubuh, yang dapat bersifat irreversible atau permanen. Kerusakan pada koklea dapat menimbulkan penurunan pendengaran permanen. Tujuan: Mengetahui gangguan pendengaran penderita TB MDR di poliklinik TB MDR Ilmu Penyakit Dalam RS Hasan Sadikin Bandung. Metode: Penelitian deskriptif secara retrospektif pada pasien TB MDR yang berobat jalan di poliklinik TB MDR Ilmu Penyakit Dalam Rumah Sakit Hasan Sadikin Bandung periode 1 Januari - 31 Desember 2013. Hasil: Didapatkan gangguan pendengaran sebanyak 20,8% dari pasien TB MDR selama mendapat terapi TB MDR dengan keluhan tinitus dan gangguan pendengaran dengan onset timbulnya keluhan di bulan ke-3 (53,3%), kemudian bulan ke-6 (40%), dan bulan ke-10 (6,7%) setelah mulai pemberian terapi TB MDR. Pada pemeriksaan audiometri nada murni ditemukan penurunan pendengaran sensorineural yang bervariasi dari derajat ringan sampai berat. Kesimpulan: Pengobatan TB MDR dapat menyebabkan penurunan pendengaran sensorineural.Kata Kunci : Tuberkulosis Multidrug Resistant, audiometri nada murni, gangguan pendengaran sensorineural ABSTRACT Background: Multidrug Resistant Tuberculosis (MDR TB) is a tuberculosis (TB) which resistant to isoniazid and rifampin, with or without resistancy to other anti-TB drugs. Aminoglycoside therapy in MDR TB patients takes risks to malfunctioning of the ear and balance system. The hearing loss and balance system impairment that appeared are irreversible/permanent. Cochlear damage can cause permanent hearing loss. Purpose: To describe hearing loss in patients with MDR TB at MDR TB clinic of internal medicine in Hasan Sadikin hospital. Methods: A retrospective descriptive study on MDR TB patients in MDR TB outpatient clinic of Internal Medicine in Hasan Sadikin hospital in the period of January 1st to December 31th, 2013. Results: There were 20,8% of MDR TB patients who received treatment for MDR TB with tinnitus and hearing loss with onset of presentation at the 3rd month (53,3%), at the 6th month (40%), and at the 10th month (6,7%) of MDR TB therapy. Pure tone audiometry examination found sensorineural hearing loss with various degrees from mild to severe. Conclusion: Treatment of MDR TB could cause sensorineural hearing loss.Keywords: Tuberculosis Multidrug Resistant, pure tone audiometric, sensorineural hearing loss
Pengaruh N–asetilsistein terhadap transpor mukosilia tuba Eustachius penderita otitis media supuratif kronis tanpa kolesteatoma Sari, Ajeng Putika; Soemantri, Johanes Bambang; Retnoningsih, Endang
Oto Rhino Laryngologica Indonesiana Vol. 45 No. 2 (2015): Volume 45, No. 2 July - December 2015
Publisher : PERHATI-KL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32637/orli.v45i2.113

Abstract

 Latar belakang: Otitis Media Supuratif Kronik (OMSK) adalah radang telinga tengah dengan perforasi membran timpani dan keluarnya sekret lebih dari 2 bulan. Pengobatan OMSK saat ini masih belum memuaskan. Peneliti mengharapkan dengan kelebihan dari N–asetilsistein (NAC) dapat memperbaiki transpor mukosilia tuba Eustachius. Tujuan: Penelitian ini bertujuan membandingkan waktu transpor dan penurunan waktu transpor mukosilia tuba Eustachius penderita OMSK tanpa kolesteatoma sebelum dan setelah diberikan pengobatan, baik pada kelompok pemberian NAC maupun pada kelompok kontrol. Metode: Uji klinis pada 24 subjek penelitian dengan desain penelitian non randomized double blind pre post test control group dengan pendekatan cohort. Hasil: Waktu transpor mukosilia yang dinilai dengan siprofloksasin pada kelompok pemberian NAC sebelum pengobatan sebesar 683,00 detik dan setelah pengobatan sebesar 279,83 detik dengan rerata selisih sebesar 403,17 detik, sedangkan pada kelompok kontrol sebelum pengobatan 538,33 detik dan sesudah pengobatan 225,00 detik dengan rerata selisih sebesar 313,33 detik. Pada penilaian dengan Methylene blue (MB) pada kelompok pemberian NAC sebelum pengobatan sebesar 118,50 detik dan setelah pengobatan sebesar 244,25 detik dengan rerata selisih sebesar 125,75 detik, pada kelompok kontrol sebelum pengobatan 100,67 detik dan sesudah pengobatan 38,33 detik dengan rerata selisih sebesar 62,33 detik. Kesimpulan: Tidak didapatkan perbedaan yang bermakna pada waktu transpor dan penurunan waktu transpor mukosilia tuba Eustachius penderita OMSK tanpa kolesteatoma sebelum dan setelah diberikan pengobatan NAC baik pada kelompok pemberian NAC maupun kelompok kontrol. Kata kunci: OMSK tanpa kolesteatoma, transpor mukosilia, N-asetilsisteinABSTRACT Background: Chronic Suppurative Otitis Media (CSOM) is a chronic inflammation of the middle ear with tympanic membrane perforation and discharges, for more than 2 months. Treatment of CSOM is still unsatisfactory. We hoped that N–acetylsistein (NAC) could improve the mucociliary transport of Eustachian tube. Purpose: To compare mucociliary transport time and the decrease of Eustachian tube mucociliary transport time in patients after and before treatment between NAC treated group and control group. Method: This was a randomized double blind pre and post test control group clinical trial with cohort approach involving 24 subjects. Result: Mucociliary transport time subjectively in NAC-treated group before and after NAC therapy were 683,00 seconds and 279,83 seconds respectively, with mean difference -403,17 seconds. Mucociliary transport time in control group before and after therapy were 538,33 seconds and 225,00 seconds respectively, with mean difference -313,33 seconds. Mucociliary transport time objectively in NAC-treated group before and after NAC therapy were 118,50 seconds and 244,25 seconds respectively, with mean difference -125,75 seconds. Mucociliary transport time in control group before and after therapy were 100,67 seconds and 38,33 seconds respectively, with mean difference -62,33 seconds. Conclusion: There was no significant difference of mucociliary transport time and the decrease of mucociliary transport time of Eustachian tube in CSOM without cholesteatoma before and after NAC treatment in both of group Keywords: CSOM without cholesteatoma, mucociliary transport, N-acetylcysteine
Korelasi otitis media dengan temuan nasoendoskopi pada penderita rinosinusitis akut Anugrahani, Ariel; Madiadipoera, Teti; Dermawan, Arif
Oto Rhino Laryngologica Indonesiana Vol. 45 No. 2 (2015): Volume 45, No. 2 July - December 2015
Publisher : PERHATI-KL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32637/orli.v45i2.114

Abstract

Latar belakang: Rinosinusitis akut adalah inflamasi pada hidung dan sinus paranasal yang berlangsung kurang dari 12 minggu. Adanya sumbatan pada hidung dapat menyebabkan sumbatan pada tuba Eustachius sehingga dapat terjadi gangguan ventilasi dan inflamasi yang dapat menimbulkan otitis media. Tujuan: Melihat adanya hubungan hidung tersumbat, nasal edema, dan rinore pada pasien rinosinusitis akut dengan otitis media. Metode: Penelitian dengan desain cross sectional study dan data diambil secara deskriptif retrospektif dari rekam medis, di Poliklinik Rinologi Alergi Ilmu Kesehatan THT-KL RSHS Bandung, dalam periode Januari 2013 - Juni 2014. Didapatkan jumlah sampel sebanyak 93 pasien yang terdiri dari 38 pasien dengan OMA, 27 pasien dengan OME, dan 28 pasien dengan OMSK, dengan usia 1 sampai 79 tahun, berdasarkan derajat berat penyakit menurut Visual Analogue Scale (VAS), gejala hidung berdasarkan Weeke, Davis dan Okuda, pemeriksaan nasoendoskopi berdasarkan Lund-Kennedy. Analisis data menggunakan uji Kruskal-Wallis, chi square (p<0,05), dan analisis korelasi Spearman. Hasil: Terdapat korelasi yang bermakna antara otitis media dengan temuan nasoendoskopi yaitu edema mukosa dan rinore. Kesimpulan: Terdapat hubungan antara peningkatan gejala obstruksi hidung dan edema mukosa serta rinore pada temuan nasoendoskopi pada penderita rinosinusitis akut dengan otitis media. Kata kunci: rinosinusitis akut, nasoendoskopi, otitis mediaABSTRACT Background: Acute rhinosinusitis is an inflammation of the nose and paranasal sinuses, which going on less than 12 weeks. If the Eustachian tube obstruction occurs, there will be ventilation and inflammatory disorders that can cause otitis media.rPurpose: This study aimed to find out the correlation of nasal obstruction, nasal edema, and rhinorrhea in acute rhinosinusitis patients with otitis media. Methods: The study was a cross sectional study which data were collected from retrospective descriptive study based on medical record at Rhinology-Allergy Clinic of ORL-HNS Department, Dr. Hasan Sadikin General Hospital, Bandung, from January 2013 to June 2014, involved 93 patients from 1 to 79 years old. Data were analyzed by using the Kruskal-Wallis, chi square, and Spearman statistical test based on anamnesis, severity of the disease using Visual Analogue Scale, nasal symptoms from Weeke, Davis and Okuda, nasoendoscopy findings from Lund-Kennedy. Results: There was a significant correlation between otitis media with mucosal edema and rhinorrhea from nasoendoscopy. Conclusion: There was a correlation between the increased symptoms of nasal obstruction,mucosal edema, and rhinorrhea in nasoendoscopy findings in patients with acute rhinosinusitis with the occurrence of otitis media. Key words: acute rhinosinusitis, nasoendoscopy, otitis media
Pengaruh tonsiloadenoidektomi terhadap kadar insulin-like growth factor-1 pada anak dengan obstructive sleep apnoea syndrome Hafiz, Al; Novialdi, Novialdi; Yerizel, Eti; Bachtiar, Hafni
Oto Rhino Laryngologica Indonesiana Vol. 45 No. 2 (2015): Volume 45, No. 2 July - December 2015
Publisher : PERHATI-KL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32637/orli.v45i2.115

Abstract

 Latar belakang: Infeksi kronis pada tonsil palatina disertai pembesaran tonsil palatina, dapat menyebabkan sumbatan pada jalan nafas bagian atas. Gangguan pertumbuhan banyak ditemukan pada kelompok pasien ini. Tujuan: Mengetahui apakah ada pengaruh tindakan tonsiloadenoidektomi terhadap kadar serum insulin-like growth factor-1 (IGF-1) dan nilai body mass index (BMI) pada anak yang menderita hipertrofi tonsil palatina dan adenoid, dengan gejala obstructive sleep apnoea syndrome (OSAS). Metode: Desain penelitian adalah eksperimental dengan studi pre- dan post-trial, dengan membandingkan kadar IGF-1 dan nilai BMI dalam serum anak dengan gejala OSAS, sebelum dan tiga bulan setelah dilakukan tonsiloadenoidektomi. Hasil: Sesuai protokol penelitian terdapat 14 subjek penelitian, menunjukkan peningkatan nilai kadar IGF-1 dan nilai BMI. Tindakan tonsiloadenoidektomi terbukti dapat meningkatkan kadar hormon pertumbuhan, yang tergambar dari peningkatan kadar IGF-1 dan nilai BMI. Kesimpulan: Tindakan tonsiloadenoidektomi berpengaruh terhadap peningkatan kadar hormon pertumbuhan, yang disimpulkan melalui pengukuran kadar IGF-1 dan nilai BMI dalam serum anak dengan gejala OSAS. Kata kunci: tonsiloadenoidektomi, insulin-like growth factor-1, obstructive sleep apnoea syndromeABSTRACT Background: Chronic infection with the enlargement of the palatine tonsil, could cause blockage of the upper airway. Growth disorders are common in this patient group. Purpose: To determine the effect of tonsilloadenoidectomy on the level of serum IGF-1 in children with palatine tonsil and adenoid hypertrophy and obstructive sleep apnoea syndrome (OSAS) symptoms. Methods: The study design was experimental, pre-and post-study, by comparing the serum levels of IGF-1 and the value of Body Mass Index (BMI) in children with OSAS symptoms, before and three months after tonsiloadenoidectomy. Result: According to the study protocol, there were 14 subjects showed increased levels of IGF-1 and BMI values. Tonsilloadenoidectomy was shown to increase the growth hormone levels, which was reflected from the increased levels of IGF-1 and BMI. Conclusion: Tonsiloadenoidectomy affected the increased levels of growth hormone, which was concluded through the measurement of the levels of IGF-1 and the value of BMI in the serum of children with symptoms of OSAS. Keywords: tonsilloadenoidectomy, insulin-like growth factor-1, obstructive sleep apnea syndrome
Perubahan kualitas hidup, eosinofil mukosa hidung, dan interleukin-5 serum pasien rinitis alergi pasca terapi Pitarini, Arinda Putri; Irawati, Nina; Poerbonegoro, Niken Lestari; Wulandari, Dewi; Badarsono, Saptawati
Oto Rhino Laryngologica Indonesiana Vol. 45 No. 2 (2015): Volume 45, No. 2 July - December 2015
Publisher : PERHATI-KL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32637/orli.v45i2.116

Abstract

 Latar belakang: Rinitis alergi adalah suatu penyakit inflamasi pada hidung yang dimediasi oleh imunoglobulin-E, yang terjadi setelah mukosa hidung terpajan alergen. Sel dan mediator inflamasi yang berperan penting adalah eosinofil, histamin, dan sitokin produk Th2. Penyakit ini ditandai dengan gejala rinorea, bersin berulang, hidung tersumbat dan/atau hidung gatal. Selain dari gejala yang mengganggu, rinitis alergi berdampak buruk terhadap kualitas hidup penderita. Tatalaksana komprehensif, meliputi penghindaran alergen, farmakoterapi, imunoterapi dan edukasi, ditujukan untuk menghilangkan gejala dan memperbaiki kualitas hidup pasien. Tujuan: Mengetahui perubahan kualitas hidup, jumlah eosinofil mukosa hidung, dan kadar IL-5 serum pada pasien rinitis alergi setelah mendapat terapi farmaka sesuai panduan. Metode: Penelitian ini merupakan studi pre-eksperimental analitik dengan pengambilan data sebelum dan sesudah pemberian farmakoterapi. Hasil: Sebanyak 31 dari 33 subjek mengalami perubahan kualitas hidup yang bermakna (MID>0,7). Seluruh pasien, 33 subjek memperlihatkan perubahan yang responsif dari jumlah eosinofil mukosa hidung. Sebanyak 30 subjek dinyatakan responsif dan terdapat penurunan kadar IL-5. Tidak ada hubungan yang bermakna antara perubahan kualitas hidup dan kadar IL-5. Kesimpulan: Perubahan kualitas hidup, jumlah eosinofil mukosa hidung, dan kadar IL-5 serum dapat digunakan sebagai penanda objektif keberhasilan terapi rinitis alergi yang dapat dipakai dalam praktik klinis sehari-hari maupun kepentingan riset. Kata kunci: rinitis alergi, kualitas hidup, eosinofil, interleukin-5ABSTRACT Background: Allergic rhinitis defined as an inflammatory disease of the nose mediated by immunoglobulin-E, induced after nasal mucosa exposure to allergen. Important inflammatory cells and mediators are eosinophils, histamine, and Th2-related cytokines. Symptoms include rhinorrhea, repeated sneezing, nasal congestion and/or nasal itching. Aside from its bothersome symptoms, allergic rhinitis decreases patient’s quality of life (QOL). Comprehensive management consist of allergen avoidance, medication, immunotherapy, and education, aimed to diminish symptoms and improve the patient’s quality of life. Purpose: To evaluate changes in quality of life, nasal mucosal eosinophil count, and level of interleukin-5 in allergic rhinitis after medicamentous treatment. Methods: This was an analytic pre-experimental study with data taken before and after medicamentous treatment. Results: Thirty-one of 33 subjects showed significant changes of QOL (MID>0,7). All samples, 33 subjects, experienced responsive changes in nasal mucosal eosinophil count. Thirty subjects were responsive, which showed decrease of IL-5 level. There was no significant relation between changes of QOL and changes of IL-5 level. Conclusion: Changes in quality of life, nasal mucosal eosinophil count, and IL-5 level are objective markers of treatment efficacy in Allergic Rhinitis, which can be used in clinical practices and researches. Keywords: allergic rhinitis, quality of life, eosinophil, interleukin-5, intranasal steroid, antihistamine

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