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Hirowati Ali
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INDONESIA
Majalah Kedokteran Andalas
Published by Universitas Andalas
ISSN : 01262092     EISSN : 24425230     DOI : https://doi.org/10.25077
Core Subject : Health,
Health Professions Medicine & Pharmacology Public Health
Majalah Kedokteran Andalas (MKA) (p-ISSN: 0126-2092, e-ISSN: 2442-5230) is a peer-reviewed, open-access national journal published by Faculty of Medicine, Universitas Andalas and is dedicated to publish and disseminate research articles, literature reviews, and case reports, in the field of medicine and health, and other related disciplines
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 792 Documents
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Hubungan kadar feritin dan asupan energi dengan tingkat kebugaran mahasiswi DIII Gizi STIKes Perintis Alya Misdhal Rini; Afriwardi Afriwardi; Edison Edison; Widia Dara
Majalah Kedokteran Andalas Vol 42, No 3S (2019): Published in November 2019
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/mka.v42.i3S.p38-47.2019

Abstract

Kebugaran jasmani merupakan salah satu indikator kesehatan yang penting. Kebugaran dipengaruhi oleh banyak faktor antara lain feritin di dalam tubuh dan asupan energi. Feritin yang rendah menyebabkan anemia, dan dapat menurunkan tingkat kebugaran  fisik. Tujuan: Untuk mengetahui hubungan kadar feritin dan asupan energi dengan tingkat kebugaran pada mahasiswi Prodi DIII Gizi STIKes Perintis Padang. Metode: Desain penelitian cross-sectional, observasi pada seluruh mahasiswi Program Studi DIII Gizi STIKes Perintis Padang. Sampel sejumlah 66 orang. Kadar feritin diperiksa di Balai Laboratorium Kesehatan Sumatera Barat dengan metode ECLIA, asupan energi dengan Food Frequency Questionaire (FFQ), dan tingkat kebugaran dengan metode Harvard Step Test. Analisis statistik yang digunakan adalah T-independen untuk mengetahui hubungan kadar feritin dan asupan energi dengan tingkat kebugaran mahasiswi. Hasil: Didapatkan rerata kadar feritin mahasiswi adalah 86,6±106,8 ng/mL; rerata asupan energi mahasiswi adalah 1688,4±484,8 kkal/hari; dan sebagian besar mahasiswi tidak bugar. Analisis statistik menunjukkan ada perbedaan yang signifikan rerata kadar feritin dalam darah dan asupan energi antara responden yang bugar dengan yang tidak bugar (p<0,05). Simpulan: Terdapat hubungan yang signifikan antara kadar feritin dan asupan energi dengan tingkat kebugaran.
Karsinoma sel skuamosa penis Gangga Mahatma; Irza Wahid
Majalah Kedokteran Andalas Vol 42, No 3S (2019): Published in November 2019
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (825.534 KB) | DOI: 10.25077/mka.v42.i3S.p57-65.2019

Abstract

Karsinoma sel skuamosa penis merupakan keganasan yang jarang yang mewakili 0,4-0,6% dari semua keganasan pada pria di Amerika Serikat dan Eropa. Di Indonesia, di RS Sardjito pada tahun 2006-2013 didapatkan insiden sejumlah 35 kasus dengan usia rata-rata 56±14,4 tahun. Karsinoma penis sering muncul dengan tampilan klinis adanya lesi yang terlihat dan teraba pada penis, bisa disertai nyeri, adanya sekret, perdarahan, atau bau busuk apabila pengobatan ditunda. Tujuan: Melaporkan kasus karsinoma sel skuamosa penis. Kasus: Dilaporkan kasus laki-laki 58 tahun dengan benjolan dan tukak yang semakin membesar di penis dengan hasil biopsi jaringan Squamous Cell Carcinoma Penis, Keratinized, Well to Moderately Differentiated. Pada pasien dilakukan total penectomy dan perineostomy. Tiga bulan kemudian pasien kembali datang dengan benjolan di lipat paha kanan hingga skrotum kanan yang semakin membesar. CT scan abdomen dengan kontras menunjukkan massa di inguinal kanan meluas sampai ke skrotum kanan dan kiri. Pasien didiagnosis dengan Squamous Cell Carcinoma Penis Stadium IV (T3N3M0) post total penectomy dan perineostomy. Metastasis kelenjar getah bening inguinal pada pasien ini ditatalaksana dengan kemoterapi regimen Cisplatin-5FU. Simpulan: Telah dilakukan dua siklus kemoterapi dengan interval 3 minggu dan hasil menunjukkan adanya respon di mana ukuran benjolan mulai mengecil.
Uptake and effect of radioiodine exposure on SKBR-3 cell lines Miftah Irramah; Yulia Kurniawati; VY Susilo; S Setiyowati; Aisyah Elliyanti
Majalah Kedokteran Andalas Vol 43, No 1 (2020): Published in January 2020
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (337.275 KB) | DOI: 10.25077/mka.v43.i1.p23-28.2020

Abstract

Radioiodine has been known as an adjuvant therapy for thyroid cancer. Beside for thyroid cell, radioiodine is reported to be taken up by breast cell. It may be proposed as an alternative for breast cancer therapy. Objective: The study aim was to analyze an uptake of radioiodine and cell proliferation rate of breast cancer cell after the exposure of radioiodine. Methods: This study used SKBR-3 cell line as representative of Human Epidermal Growth Factor Receptor (HER2+) subtype. The cells were planted in DMEM medium added 10% fetal bovine serum (FBS), panstrep 1% and amphotericin B. The cells were grown until 80% confluent and then stripped. Subsequently the cells were sub-cultured on plates 12 and 6 wells respectively for measured uptake of radioiodine and cell proliferation rate after the exposure. Radioiodine uptake was calculated by sum efflux of 125 Iodine (125I) and the amount of uptake after the addition of 95% ethanol. Cell proliferation rate was measured by calculated by using clonogenic assay after iodine-131 (131I) exposure. Results: The average of iodine uptake was 194±50 cpm/106 cell. The average cell proliferation after radioiodine exposure was 54%±5%; Conclusions: Radioiodine is taken by SKBR-3 cells and it reduced cell proliferation rate. This finding shows an opportunity for radioiodine as an alternative therapy for breast cancer. Another studies are needed to understand of cell death the mechanism.
Preface and ToC - Vol 43, No 1 (2020) Redaksi MKA
Majalah Kedokteran Andalas Vol 43, No 1 (2020): Published in January 2020
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (328.689 KB)

Abstract

Preface and ToC - Vol 41, No 1 (2018) Redaksi MKA
Majalah Kedokteran Andalas Vol 41, No 1 (2018): Published in January 2018
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (318.94 KB)

Abstract

Korelasi resistive index ginjal dengan proteinuria pada pasien diabetes melitus tipe 2 Achi Rasma Welaty; Nurlaily Idris; Bachtiar Murtala; Andi Alfian Zainuddin; Hasyim Kasim; Nikmatia Latief
Majalah Kedokteran Andalas Vol 43, No 1 (2020): Published in January 2020
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (637.312 KB) | DOI: 10.25077/mka.v43.i1.p29-37.2020

Abstract

Tujuan: Penelitian ini bertujuan mengetahui korelasi resistive index ginjal dengan proteinuria pada pasien diabetes melitus tipe 2. Metode: Penelitian ini dilakukan di Bagian Radiologi RS Pendidikan Universitas Hasanuddin Makassar pada Maret s/d Juni 2019. Penelitian ini adalah penelitian deskriptif dengan kajian potong lintang. Pertama dilakukan penilaian proteinuria, perhitungan eGFR, dan melakukan ultrasonografi Doppler sehingga mendapatkan nilai resistive index. Analisis data statistik melalui uji korelasi Spearman. Sampel penelitian ini sebanyak 82 sampel dengan 41 sampel disertai proteinuria dan dengan 41 sampel tanpa disertai proteinuria. Hasil: Penelitian menunjukkan korelasi kuat antara resistive index ginjal dengan proteinuria (r=0,449 dan r=0,551) dan memiliki hubungan yang signifikan (p<0,0001). Untuk korelasi resistive index ginjal dengan eGFR terdapat korelasi yang kuat (r=0,604 dan r=0,666) serta hubungan yang signifikan (p<0,0001). Dan terdapat korelasi yang cukup antara proteinuria dengan eGFR serta memiliki hubungan yang signifikan (r=0,449; p<0,0001). Simpulan: Semakin tinggi kadar proteinuria, maka semakin tinggi nilai resistive index ginjal pada pasien diabetes melitus tipe 2. Terdapat hubungan yang cukup kuat antara resistive index ginjal kanan dan kiri dengan eGFR pada pasien diabetes melitus tipe 2. Dimana semakin tinggi nilai resistive index ginjal, maka semakin rendah nilai eGFR (semakin tinggi stadium PGK).
Preface and ToC - Vol 42, No 3S (2019) Redaksi MKA
Majalah Kedokteran Andalas Vol 42, No 3S (2019): Published in November 2019
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (331.392 KB)

Abstract

Prognostic factors influencing prolonged ventilation after open mitral valve surgery Supomo Supomo
Majalah Kedokteran Andalas Vol 43, No 1 (2020): Published in January 2020
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (243.266 KB) | DOI: 10.25077/mka.v43.i1.p1-7.2020

Abstract

Objective: To determine prognostic factors influencing prolonged ventilation after surgery in our hospital. Method: Seventy-five patients fulfilled inclusion criteria were included in this retrospective cross-sectional study. Prognostic factors analyzed were age, chronic pulmonary disease, heart failure (NYHA class function), left ventricular (LV) dysfunction (based on ejection fraction), recent myocardial infarction, pulmonary hypertension (PH), duration of cardiopulmonary bypass (CPB), ischemic time and aorta clamp time, which were analyzed in relation to prolonged ventilation after open mitral valve surgery. Results: Subjects were 75 patients aged between 19 and 62 years old (mean 39.76, SD 11.44) whom underwent open mitral valve repair or replacement surgery. Twenty-three patients (30.67%) had prolonged ventilation (≥24 hours) after surgery. Bivariate analysis showed there were no significant correlation between age, heart failure, PH and LV dysfunction. There are different with statistically significance between groups (p<0.05). Conclusions: In this study, almost one-third of patients had prolonged ventilation after surgery. Factors influencing this morbidity were the duration of ischemic time, aorta clamp time and CPB. Age, heart failure, LV dysfunction and PH were not statistically related to the prolonged ventilation event.
Preface and ToC - Vol 41, No 2 (2018) Redaksi MKA
Majalah Kedokteran Andalas Vol 41, No 2 (2018): Published in May 2018
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (318.198 KB)

Abstract

Is narrow qrs complex tachyarrythmia always from supraventricular? Tiya Setiadi; Hauda El Rasyid
Majalah Kedokteran Andalas Vol 43, No 1 (2020): Published in January 2020
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1354.9 KB) | DOI: 10.25077/mka.v43.i1.p38-46.2020

Abstract

Idiopathic left ventricular tachycardia (previously known as fascicular VT) is characterized by right bundle branch block (RBBB) left axis ventricular tachycardia (VT) with a relatively narrow QRS (120–140 ms) in young patients and sensitive to verapamil. Objective: To remind that not all tachyarrhythmias with relatively narrow QRS are derived from supraventricular. Cases: First case of 23 years old man with chief complain palpitation and presyncope with narrow QRS ventricular tachycardia electrocardiography (ECG). Second case of 16 years old man with chief complain palpitation with narrow QRS ventricular tachycardia ECG, both of them are getting better after administration of diltiazem and verapamil. Conclusions: Idiopathic left ventricular tachycardia is associated with presyncope, palpitation and was successfully terminated with verapamil. Medical management is variable in its outcomes and given the age of the population affected. Narrow QRS complex tachycardia not always from supraventricular, we should think about ventricular tachycardia especially ILVT if there is no structural heart disease.

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