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JCPS (Journal of Current Pharmaceutical Sciences)
Published by Universitas Muhammadiyah Banjarmasin
ISSN : 25982087     EISSN : 25982095     DOI : -
Core Subject : Health,
Medicine & Pharmacology
Journal of Current Pharmaceutical Sciences is a scholarly journal and expects to Publish articles related to the science of pharmaceutical science became the main focus of the problem at this time. This journal may publish research results as well as the results of theoretical studies and reviews. JCPS has had an ISSN print version 2598-2087 and has an online version 2598-2095 since Vo. 1 No.1 year 2017.
Arjuna Subject : -
Articles 6 Documents
 1 
Search results for , issue "Vol 3 No 2 (2020): March 2020" : 6 Documents clear
PROFIL KEYAKINAN SAKIT PADA PASIEN HIPERTENSI DI PUSKESMAS Yusrinie Wasiaturrahmah
JCPS (Journal of Current Pharmaceutical Sciences) Vol 3 No 2 (2020): March 2020
Publisher : LPPM - Universitas Muhammadiyah Banjarmasin

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Abstract

Hipertensi atau peningkatan tekanan darah dimana tekanan darah sistolik 140 mmHg dan atau tekanan darah diastolik 90 mmHg dapat menyebabkan komplikasi yang lebih berbahaya. Hipertensi memerlukan pengobatan jangka panjang, sehingga kepatuhan pasien dalam pengobatan merupakan faktor penting untuk tercapainya target terapi. Salah satu faktor yang mempengaruhi kepatuhan pengobatan adalah keyakinan sakit (illness beliefatau illness perceptions) pasien terhadap penyakitnya. Keyakinan sakit mempengaruhi perilaku seseorang untuk mengambil atau tidak mengambil pengobatan. Tujuan penelitian untuk memberikan profile atau gambaran keyakinan sakit pasien hipertensi terhadap penyakitnya. Penelitian ini merupakan penelitian deskriptif dengan menggunakan Brief Illness Perception Questionnaire (BIPQ) untuk mengukur keyakinan sakit pasien hipertensi pada 100 responden. Hasil penelitian menunjukkan rata-rata skor total BIPQ pada penelitian ini sebesar 38,56(±7,389) yang berarti responden memiliki persepsi atau pandangan bahwa hipertensi merupakan penyakit yang tidak mengancam bagi mereka. Pasien sebagian besar mengurutkan bahwa penyebab hipertensi disebabkan oleh gaya hidup, stress dan keturunan (27%).
GAMBARAN POTENSI INTERAKSI OBAT PADA PERESEPAN PASIEN DIABETES MELITUS TIPE 2 DI APOTEK X (Overview of Potential Drug Interactions in Prescribing Type 2 Diabetes Mellitus Patients in Pharmacies X) Baiti Hayati; herda ariyani; ruslina wati
JCPS (Journal of Current Pharmaceutical Sciences) Vol 3 No 2 (2020): March 2020
Publisher : LPPM - Universitas Muhammadiyah Banjarmasin

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Abstract

ABSTRAK Diabetes Melitus (DM) merupakan penyakit metabolik yang ditandai dengan hiperglikemia kronis akibat defek pada sekresi insulin, aksi insulin atau keduanya. Interaksi obat merupakan satu dari masalah yang terkait obat yang diidentifikasi sebagai kejadian atau keadaan terapi obat yang dapat mempengaruhi outcome klinis pasien. Penelitian ini bertujuan untuk mengetahui gambaran potensi interaksi obat pada peresepan pasien diabetes melitus tipe 2 di Apotek X Banjarmasin. Penelitian ini merupakan jenis penelitian deskriptif dengan metode retrospektif. Pengumpulan lembar resep pasien yang berisikan obat antidiabetika di Apotek X pada tanggal 23, 24 dan 27 Januari 2020. Teknik pengambilan sampel dengan teknik insidental sampling dikaji berdasarkan literatur dan diolah dalam bentuk tabel dengan menghitung persentasenya. Hasil penelitian dari 27 resep, pasien diabetes terbanyak terdapat pada jenis kelamin perempuan sebanyak (66,67%) dan berusia 55-64 tahun (44,44%). Besar persentase terjadinya potensi interaksi obat sebesar (81,48%). Kejadian interaksi obat berdasarkan mekanisme yaitu farmakodinamik 30 kejadian (76,92%), farmakokinetik 2 kejadian (5,12%) dan tidak diketahui 7 kejadian (17,94%). Kategori tingkat keparahan interaksi obat yang paling besar yaitu moderat sebanyak 33 kejadian (84,61%) dan minor sebanyak 6 kejadian (15,38%). Obat antidiabetika yang paling banyak menimbulkan potensi interaksi obat yaitu metformin sebanyak 15 kejadian. Kata Kunci : Diabetes melitus, Potensi interaksi obat, Obat Antidiabetika, Resep ABSTRACT Diabetes mellitus (DM) is a metabolic disease characterized by chronic hyperglycemia due to defects in insulin secretion, insulin action or both. Drug interactions are one of the drug-related problems that are identified as drug therapy events or conditions that can affect a patient's clinical outcome. This study aims to determine the potential for drug interactions in prescribing type 2 diabetes mellitus patients at Pharmacy X Banjarmasin. This research is a type of descriptive research with a retrospective method. Collection of patient prescription sheets containing antidiabetic drugs at Pharmacy X on January 23, 24 and January 27, 2020. Sampling techniques with incidental sampling techniques were a ssessed based on literature and processed in tabular form by calculating the percentage. The results of the 27 recipes, most diabetes patients found in female sex (66.67%) and aged 55-64 years (44.44%). Large percentage of potential drug interactions amounted to (81.48%). The mechanism of drug interaction based on the mechanism is pharmacodynamics 30 events (76.92%), pharmacokinetics 2 events (5.12%) and 7 events (17.94%) unknown. The category of the severity of drug interactions with the highest is moderate with 33 events (84.61%) and minor with 6 events (15.38%). The antidiabetic drugs that cause the most potential drug interactions are 15 events metformin. Keywords: Diabetes mellitus, potential drug interactions, antidiabetic drugs, recipes
Pengaruh Propilen glikol dan Menthol sebagai Enhancer terhadap Sifat Fisik serta Indeks Iritasi Kulit dalam Sediaan Gel Meloksikam Asa Falahi
JCPS (Journal of Current Pharmaceutical Sciences) Vol 3 No 2 (2020): March 2020
Publisher : LPPM - Universitas Muhammadiyah Banjarmasin

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Abstract

ABSTRAK Meloksikam adalah obat golongan anti inflamasi non-steroid (AINS) yang banyak digunakan untuk mengobati nyeri dan inflamasi. Penggunaan oral Meloksikam dapat menimbulkan berbagai efek samping sistemik. Pemakaian transdermal diketahui mampu mencapai konsentrasi efektif pada jaringan target, dengan konsentrasi plasma yang lebih rendah dibanding penggunaan oral, sehingga dapat mengurangi resiko efek samping sistemiknya. Penelitian ini bertujuan untuk membuat sediaan emulgel untuk penghantaran transdermal Meloksikam. Propilenglikol 10% dan menthol 3% digunakan sebagai peningkat penetrasi. Sediaan dievaluasi meliputi pengamatan organoleptik, pH, viskositas, daya sebar serta pengujian stabilitas fisik menggunakan metode freeze thaw. Sediaan emulgel memenuhi persyaratan sifat fisik yang ditentukan baik sebelum maupun setelah kurun waktu penyimpanan 3 siklus pada suhu freeze dan thaw. Efektifitas anti inflamasi paling baik ditunjukan pada formula 3 yaitu emulgel dengan enhancer menthol.
The Effect of Olive Oil, VCO, and Corn Oil with Adeps Lanae and Vaselin Alba Variation to Physical Characteristic of Methyl Salicylic Stick Balm Anisa Amalia
JCPS (Journal of Current Pharmaceutical Sciences) Vol 3 No 2 (2020): March 2020
Publisher : LPPM - Universitas Muhammadiyah Banjarmasin

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Abstract

AbstractThe physical characteristic of stick balm have been affected the consistency and comfortness at the time of used. Components that affected the physical properties of stick balm were components of fats and oils. Fat used were adeps lanae and vaseline alba, as it can prevented the tendency to split up oil. The components of the oil used were the VCO which had saturated fatty acids, olive oil and corn oil which had not saturated fatty acids which could affected the melting point and hardness. Based on the foregoing, the comparison of oil type with variations of adeps lanae and vaseline alba carried out towards the physical characteristic of stick balm methyl salicylate. The purpose of this research was to knew the effect of olive oil, corn oil and VCO with variations of adeps lanae and vaseline alba towards the physical properties of stick blam. Adeps lanae and vaselin alba concentration was 10%. Characterization performed on stick balm which included analysis of organoleptics, the melting point and hardness. Results indicate formula with adeps lanae more colored yellow. Homogeneity test of each formula showed that the stick balm was homogeneous. On the hardness and melting point assay, the results qualified on 3.3 mm - 4.16 mm and 51.25 0C - 56.52 0C. A summary of this research was the used of adeps lanae with VCO delivered the highest melting point on 56.52 ºC and the most violent both with translucent 3.33 mm depth. Keywords: physical characteristic, stick balm, a type of oil, variations of adeps lanae and vaseline alba
UJI DAYA HAMBAT EKSTRAK ETANOL DAUN GANDARIA (Bouea macrophylla Griff) TERHADAP PERTUMBUHAN BAKTERI Staphylococcus aureus dan Escherichia coli Eka Astuty Rachman
JCPS (Journal of Current Pharmaceutical Sciences) Vol 3 No 2 (2020): March 2020
Publisher : LPPM - Universitas Muhammadiyah Banjarmasin

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Abstract

Penyakit infeksi saat ini menjadi masalah yang cukup serius di negara berkembang. Penyakit infeksi dapat ditangani dengan penggunaan antibakteri. Bila penggunaan antibakteri tidak rasional akan menyebabkan resistensi antibiotik. Tanaman gandaria (Bouea macrophylla Griff) merupakan tanaman yang memiliki potensial sebagai antibakteri. Peneltian ini bertujuan untuk mengetahui daya hambat ekstrak etanol daun gandaria (Bouea macrophylla Griff). Konsentrasi ekstrak etanol yang digunakan adalah 10%, 15%, 20%, 25%, 30%, 40%, 80% dan 100%. Uji aktivitas antibakteri terhadap bakteri Staphylococcus aureus dan Escherichia coli menggunakan metode difusi cakram. Hasil uji menunjukkan bahwa semua konsentrasi ekstrak etanol memiliki kemampuan untuk menghambat pertumbuhan bakteri Staphylococcus aureus dengan konsentrasi 10%, 15%, 20%, 25%, 30%, 40%, 80% dan 100% dengan masing-masing zona hambat adalah 10,70 mm, 10,83 mm, 11,13 mm, 11,34 mm, 11,40 mm, 14,97 mm, 16,03 mm, dan 16,07. Sedangkan untuk bakteri Escherichia coli, ekstrak etanol daun gandaria tidak memiliki zona hambat. Analisis data menggunakan one way ANOVA dan uji lanjut menggunakan uji Duncan Multiple Range Test memperoleh nilai signifikansi 0,000 (sig<0,05). Hal ini berarti secara statistik esktrak etanol daun gandaria berpengaruh terhadap daya hambat pertumbuhan bakteri Staphylococcus aureus
REVIEW TEKNIK MIKROENKAPSULASI PADA EKSTRAK MANGOSTEEN Rosa Riau Wati; Sriwidodo Sriwidodo; Anis Yohana Chaerunisa
JCPS (Journal of Current Pharmaceutical Sciences) Vol 3 No 2 (2020): March 2020
Publisher : LPPM - Universitas Muhammadiyah Banjarmasin

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Abstract

Mangosteen ( Garcinia mangostana L. ) is a popular tropical fruit that is widely found in southeast Asia . One of the important compounds in mangosteensal extract is Xanthones which underlies its various pharmacological activities . Mangosteen has characteristics, is unstable, reactivity , and is very easily oxidized, as well as poor solubility and bioavability. which can inhibit the formulation process. So that the microencapsulation method is used to protect the bioactive compounds in mangosteen extract, namely xanthones so that they can last a long time and can still be utilized properly by the body. Microencapsulation is the process by which a liquid is packaged or coated by a polymeric material . to produce micro sizes, called microcapsules . There are several methods of microencapsulation, frezee draying, spray draying, cooling, fluid bed coating, coacervation, and liposome entrapment . in the microencapsulation technique the material used in coating can be in the form of a polymer. Each polymer has different characteristics and purpose of use and variations of polymers that are tailored to the needs. The polymer to be used is capable of providing a cohesive thin layer with core material and chemically blended but still inert. Keyword: Mangosteen , Microencapsulation, Method, Polymer

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