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PENGARUH USIA DAN JENIS KELAMIN PADA KEPATUHAN PASIEN DIABETES MELITUS MENGGUNAKAN OBAT ANTIDIABETES DI PERUM KETAPANG SOKARAJA KULON Ikhwan Yuda Kusuma
Viva Medika Vol 11 No 3 (2018)
Publisher : Universitas Harapan Bangsa Purwokerto

ABSTRACT The WHO survey results show that the number of DM patients in Indonesia is ranked the 4th largest in the world. DM causes death by 5% every year. Deaths from DM are expected to increase by 50% in the next ten years. The results of the 2007 Central Java RISKESDAS showed that the prevalence of DM in Central Java province was 0.8% and overall was 1.3%. The highest prevalence is found in Cilacap Regency (3.9%), second place is Tegal City Regency (3.1%), for the third place is Surakarta (2.8%), fourth place is Pemalang (2.1%), and fifth place is occupied by Banyumas (1.9%) (Ministry of Health, 2009). This study used an experimental design by treating the group of cases. The research instruments in this study were interview guides about the number of remaining antidiabetic drugs to check the compliance and MMAS questionnaires that had been validated and translated into Indonesian versions (Setyaningsih, 2013). The results of data analysis using the Chi-Square test were obtained p = 0.220 (p> 0.05) based on the MMAS questionnaire, this indicates that this indicates that this study of age has a significant influence on the adherence of antidiabetic use in DM patients in Perum Ketapang Sokaraja Kulon. Keywords: Age, Diabetes Mellitus, Drug Information

IDENTIFIKASI FLAVANOID PADA EKSTRAK DAUN MELINJO (GENATUM GENANOM L.) putriana rahmawati
Viva Medika Vol 11 No 1 (2017)
Publisher : Universitas Harapan Bangsa Purwokerto

Abstract Melinjo plants are an abundant food commodity in Indonesia and have many benefits for consumption ranging from young leaves, flowers, seeds, to the skin. According to Voondan Kueh (1999) all foods derived from melinjo plants have a high nutritional component, such as carbohydrates at 6.60%, protein at 4.20%, calcium at 94.00 mg, vitamins C1, 500 mg and others. The method of this research is Uv-Vis spectrophotometry analysis performed on melinjo leaf samples by measuring the standard absorbance of quercetin flavonoids at a wavelength of 424 nm. The results showed that the content of melinjo leaf flavonoids (Gnetum gnemon L) in Rempoah village was higher than the content of melinjo leaf flavonoids (Gnetum gnemon L) in Dukuh Waluh Village. Rempoah village has a solid soil texture, which causes the roots to easily absorb water from the soil because the particles of soil can hold back the rate of water so that the roots of plants easily absorb water, as a result the plant growth is also getting better. Shown with the content of flavonoid pigments that are better than Dukuh Waluh Village. Whereas in the Dukuh Waluh area the sandy and gravel soil structure results in very weak water binding capacity because the soil particles are too tenuous as a result of lack of water supply so that plant growth is also not good, so there is less flavonoid content. Solid soil causes the roots to easily handle mineral salts and results in increased secondary metabolite content. Keywords: mlinjo, determination, flavanoids

PENETAPAN KADAR FLAVANOID TOTAL EKSTRAK DAUN MELINJO (GENATUM GENANOM L.) DENGAN ANALISIS SPEKTROFOTOMETRI UV-VIS putriana rahmawati
Viva Medika Vol 11 No 1 (2017)
Publisher : Universitas Harapan Bangsa Purwokerto

Abstract Melinjo plants are an abundant food commodity in Indonesia and have many benefits for consumption ranging from young leaves, flowers, seeds, to the skin. According to Voondan Kueh (1999) all foods derived from melinjo plants have a high nutritional component, such as carbohydrates at 6.60%, protein at 4.20%, calcium at 94.00 mg, vitamins C1, 500 mg and others. The method of this research is Uv-Vis spectrophotometry analysis performed on melinjo leaf samples by measuring the standard absorbance of quercetin flavonoids at a wavelength of 424 nm. The results showed that the content of melinjo leaf flavonoids (Gnetum gnemon L) in Rempoah village was higher than the content of melinjo leaf flavonoids (Gnetum gnemon L) in Dukuh Waluh Village. Rempoah village has a solid soil texture, which causes the roots to easily absorb water from the soil because the particles of soil can hold back the rate of water so that the roots of plants easily absorb water, as a result the plant growth is also getting better. Shown with the content of flavonoid pigments that are better than Dukuh Waluh Village. Whereas in the Dukuh Waluh area the sandy and gravel soil structure results in very weak water binding capacity because the soil particles are too tenuous as a result of lack of water supply so that plant growth is also not good, so there is less flavonoid content. Solid soil causes the roots to easily handle mineral salts and results in increased secondary metabolite content. Keywords: mlinjo, determination, flavanoids

PENGARUH PENGGUNAAN VARIASI KONSENTRASI AVICEL PH-101 PADA FORMULA TABLET PREDNISOLONE hilda suherman
Viva Medika Vol 11 No 1 (2017)
Publisher : Universitas Harapan Bangsa Purwokerto

Abstract Prednisolone is a steroid class drug that is used to treat certain types of allergies, inflammatory conditions, autoimmune disorders and cancer. Solubility of prednisolone is very difficult to dissolve in water causing problems in the absorption process so that the optimum formula is needed to form Prednisolone tablets that meet the requirements of the physical properties of tablets. The purpose of this study was to make the optimum formula with a combination of lactose excipients, avicel pH-101, and amprotab to obtain prednisolone tablets with good physical properties and dissolution. Prednisolone tablets made 7 formulas with a combination of lactose (A) Avicel PH-101 (B), and Amprotab (C), Formula I (100% A); Formula II (100% B); Formula III (100% C); Formula IV (50% A + 50% B); Formula V (50% A + 50% C); Formula VI (50% B + 50% C); Formula VII (33.33% A + 33.33% B + 33.33% C) in 2 batches. The method of making prednisolone tablets by direct printing. Testing of prednisolone tablets included the physical properties of tablets, weight uniformity, uniformity in size, hardness, friability, disintegration time, and dissolution test, and content determination. Keywords: optimization of formulas, tablets, Prednisolone, Simplex Lattice Design.

PENGARUH PENGGUNAAN VARIASI KONSENTRASI AVICEL PH-101 PADA FORMULA TABLET PREDNISOLONE hilda suherman
Viva Medika Vol 11 No 1 (2017)
Publisher : Universitas Harapan Bangsa Purwokerto

Abstract Prednisolone is a steroid class drug that is used to treat certain types of allergies, inflammatory conditions, autoimmune disorders and cancer. Solubility of prednisolone is very difficult to dissolve in water causing problems in the absorption process so that the optimum formula is needed to form Prednisolone tablets that meet the requirements of the physical properties of tablets. The purpose of this study was to make the optimum formula with a combination of lactose excipients, avicel pH-101, and amprotab to obtain prednisolone tablets with good physical properties and dissolution. Prednisolone tablets made 7 formulas with a combination of lactose (A) Avicel PH-101 (B), and Amprotab (C), Formula I (100% A); Formula II (100% B); Formula III (100% C); Formula IV (50% A + 50% B); Formula V (50% A + 50% C); Formula VI (50% B + 50% C); Formula VII (33.33% A + 33.33% B + 33.33% C) in 2 batches. The method of making prednisolone tablets by direct printing. Testing of prednisolone tablets included the physical properties of tablets, weight uniformity, uniformity in size, hardness, friability, disintegration time, and dissolution test, and content determination. Keywords: optimization of formulas, tablets, Prednisolone, Simplex Lattice Design.

PENGARUH FAKTOR USIA, JENIS KELAMIN, DAN PENGETAHUAN TERHADAP SWAMEDIKASI OBAT hilda suherman
Viva Medika Vol 11 No 3 (2018)
Publisher : Universitas Harapan Bangsa Purwokerto

Abstract Self-medication is a human effort to treat diseases or symptoms of minor ailments such as fever, cough, flu, pain and others without a doctor's prescription. In practice, limited knowledge of drugs and their use can be a source of medication errors (medication error). This research was conducted with a cross sectional descriptive research method. Data was collected through a validated questionnaire filling technique. A total of 300 respondents involved in this study were selected by consecutive sampling method from 3 pharmacies in the city of Purwokerto which were determined proportionally according to the population of each pharmacy. Data were analyzed by Chi-square test and Fisher's test used Statistical Product and Servicer Solution (SPSS) version 17. The results showed that the patient's knowledge level was 22.6% classified as poor, 48% classified as moderate, and 29.4% classified as good. The use of self-medication is 26.3% irrational and 73.7% rational. Based on the results of the Chi-square and Fisher test, the level of knowledge is influenced by age, recent education, and occupation. While self-medication rationality is not influenced by gender, education and employment. Based on the results of the study, it was found that the patient's level of knowledge was classified as moderate with a percentage of 48%. While self-administered rationality is classified as rational with a percentage of 73.7%. Keywords: self-medication, pharmacy, rationality of drug use

GAMBARAN PIO SWAMEDIKASI APOTEKER DALAM PENATALAKSANAAN FLU hilda suherman
Viva Medika Vol 11 No 3 (2018)
Publisher : Universitas Harapan Bangsa Purwokerto

Abstract Self-medication is a human effort to treat diseases or symptoms of minor ailments such as fever, cough, flu, pain and others without a doctor's prescription. In practice, limited knowledge of drugs and their use can be a source of medication errors (medication error). This research was conducted with a cross sectional descriptive research method. Data was collected through a validated questionnaire filling technique. A total of 300 respondents involved in this study were selected by consecutive sampling method from 3 pharmacies in the city of Purwokerto which were determined proportionally according to the population of each pharmacy. Data were analyzed by Chi-square test and Fisher's test used Statistical Product and Servicer Solution (SPSS) version 17. The results showed that the patient's knowledge level was 22.6% classified as poor, 48% classified as moderate, and 29.4% classified as good. The use of self-medication is 26.3% irrational and 73.7% rational. Based on the results of the study, it was found that the patient's level of knowledge was classified as moderate with a percentage of 48%. While self-administered rationality is classified as rational with a percentage of 73.7%. Keywords: Self-medication, Pharmacy, Knowledge, Rationality of drug use

FORMULASI SEDIAAN MASKER ANTIOKSIDAN DARI EKSTRAK TEH HIJAU (CAMELLIA SINENSIS) desi nawangsari
Viva Medika Vol 11 No 3 (2018)
Publisher : Universitas Harapan Bangsa Purwokerto

Abstract Research has been carried out on the formulation of maskantioxidant preparations containing green tea leaf extract. The study begins with testing the antioxidant activity of ethanol extract of green tea leaves with a free radical reduction method of 1,1-diphenyl-2-picrylhydrazyl using visible spectrophotometry. Testing of antioxidant activity showed that the ethanol extract of green tea leaves gave an IC50 value of 3.17µg / mL. Formulations of gel masks made were F0 (base without active substances), F1 (base + concentration of ethanol extract of green tea leaves for IC50 (0,000317%)), F2 (base + concentration of ethanol extract of green tea leaves for 50xIC50 (0, 0158%)), F3 (base + concentration of ethanol extract of green tea leaves for 100xIC50 (0.0317%)), F4 (base + concentration of ethanol extract of green tea leaves for IC50), F5 (base + concentration of ethanol extract of green tea leaves worth IC50), F6 (base + concentration of ethanol extract of green tea leaves for IC50. Evaluation of gel mask preparations include, organoleptic examination and homogeneity, pH, viscosity, dry time of preparation and testing of antioxidant stability. F2 provides better and higher free radical reduction activity than products on the market. F4, F5, F6 shows an increase in free radical reduction activity. Keywords: Green tea leaves (Camellia sinensis L.), DPPh, IC50 gel mask.

EVALUASI SEDIAAN MASKER ANTIOKSIDAN DARI EKSTRAK DAUN TEH HIJAU (CAMELLIA SINENSIS) desi nawangsari
Viva Medika Vol 11 No 3 (2018)
Publisher : Universitas Harapan Bangsa Purwokerto

Abstract Green tea (Camellia sinensis L.) has the main efficacy as an antioxidant and contains polyphenol compounds in green tea leaves with the main component of polyphenol fraction namely Epigallocatechin-3-gallate (EGCG) which has strong activity to prevent free radicals that cause premature aging. Research has been carried out on the formulation of maskantioxidant preparations containing green tea leaf extract. The study begins with testing the antioxidant activity of ethanol extract of green tea leaves with a free radical reduction method of 1,1-diphenyl-2-picrylhydrazyl using visible spectrophotometry. Testing of antioxidant activity showed that the ethanol extract of green tea leaves gave an IC50 value of 3.17µg / mL. Formulations of gel masks made were F0 (base without active substances), F1 (base + concentration of ethanol extract of green tea leaves for IC50 (0,000317%)), F2 (base + concentration of ethanol extract of green tea leaves for 50xIC50 (0, 0158%)), F3 (base + concentration of ethanol extract of green tea leaves for 100xIC50 (0.0317%)), F4 (base + concentration of ethanol extract of green tea leaves for IC50), F5 (base + concentration of ethanol extract of green tea leaves worth IC50), F6 (base + concentration of ethanol extract of green tea leaves for IC50. Evaluation of gel mask preparations include, organoleptic examination and homogeneity, pH, viscosity, dry time of preparation and testing of antioxidant stability. F2 provides better and higher free radical reduction activity than products on the market. F4, F5, F6 shows an increase in free radical reduction activity. Keywords: Green tea leaves (Camellia sinensis L.), DPPh, IC50 gel mask.

UJI AKTIVITAS SEDIAAN MASKER ANTIOKSIDAN DARI EKSTRAK DAUN TEH HIJAU (CAMELLIA SINENSIS) desi nawangsari
Viva Medika Vol 11 No 3 (2018)
Publisher : Universitas Harapan Bangsa Purwokerto

Abstract Green tea (Camellia sinensis L.) has the main efficacy as an antioxidant and contains polyphenol compounds in green tea leaves with the main component of polyphenol fraction namely Epigallocatechin-3-gallate (EGCG) which has strong activity to prevent free radicals that cause premature aging. Research has been carried out on the formulation of maskantioxidant preparations containing green tea leaf extract. The study begins with testing the antioxidant activity of ethanol extract of green tea leaves with a free radical reduction method of 1,1-diphenyl-2-picrylhydrazyl using visible spectrophotometry. Testing of antioxidant activity showed that the ethanol extract of green tea leaves gave an IC50 value of 3.17µg / mL. Formulations of gel masks made were F0 (base without active substances), F1 (base + concentration of ethanol extract of green tea leaves for IC50 (0,000317%)), F2 (base + concentration of ethanol extract of green tea leaves for 50xIC50 (0, 0158%)), F3 (base + concentration of ethanol extract of green tea leaves for 100xIC50 (0.0317%)), F4 (base + concentration of ethanol extract of green tea leaves for IC50), F5 (base + concentration of ethanol extract of green tea leaves worth IC50), F6 (base + concentration of ethanol extract of green tea leaves for IC50. Evaluation of gel mask preparations include, organoleptic examination and homogeneity, pH, viscosity, dry time of preparation and testing of antioxidant stability. F2 provides better and higher free radical reduction activity than products on the market. F4, F5, F6 shows an increase in free radical reduction activity. Keywords: Green tea leaves (Camellia sinensis L.), DPPh, IC50 gel mask.

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Contact Name
Fauziah Hanum Nur Adriyani

Contact Email
fauziahhanum@uhb.ac.id

Phone
-

Journal Mail Official
fauziahhanum@uhb.ac.id

Editorial Address
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Location
Kab. banyumas,

Jawa tengah

INDONESIA

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Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name Fauziah Hanum Nur Adriyani

Contact Email fauziahhanum@uhb.ac.id

Phone -

Journal Mail Official fauziahhanum@uhb.ac.id

Editorial Address -

Location Kab. banyumas, Jawa tengah INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Contact Name
Fauziah Hanum Nur Adriyani

Contact Email
fauziahhanum@uhb.ac.id

Phone
-

Journal Mail Official
fauziahhanum@uhb.ac.id

Editorial Address
-

Location
Kab. banyumas,

Jawa tengah

INDONESIA