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INDONESIA
Jurnal Respirasi (JR)
Published by Universitas Airlangga
ISSN : 24070831     EISSN : 26218372     DOI : -
Core Subject : Health,
Jurnal Respirasi is a National journal in accreditation process managed by Department of Pulmonology & Respiratory Medicine Faculty of Medicine Airlangga University - Dr. Soetomo General Hospital, Surabaya. Publish every January, May, September every year with each of 5 (five) complete texts in Indonesian.
Arjuna Subject : -
Articles 321 Documents
POTT’S Disease Tutik Kusmiati; Hapsari Paramita Narendrani
Jurnal Respirasi Vol. 2 No. 3 (2016): September 2016
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (598.564 KB) | DOI: 10.20473/jr.v2-I.3.2016.99-109

Abstract

Pott's disease, sometimes reffered to tuberculous spondylitis, is an infection of tuberculosis that affects one or more vertebrae, which first described by Percival Pott. Tuberculous spondylitis is the most dangerous form of musculoskeletal tuberculosis because it can cause bone destruction, deformity and paraplegia. The spine is the most commonly affected due to bony dissemination of tuberculosis in bones. The deployment through the arteries, veins via Batson plexus and percontinuitatum by the spread of abscess paravertebral. The spread of tuberculosis infection will cause inflammation in paradiscs, and causes progressive bone destruction and then will make vertebral collapse and deformity arising shaped kyphosis (posterior angulation) called gibbus. Early diagnosis is often difficult, MRI is the best diagnostic tools for pott's disease. Tissue culture or spesimen of M. tuberculosis important to confirm the diagnosis. Medical treatment is preferred, whereas surgical therapy as a complements. Drop out of anti-tuberculous drugs is a major challenge for the treatment of spinal TB with MDR because of long duration of therapy and the cost. The prognosis for spinal TB increases with early diagnosis and rapid intervention.
Faal Paru Difusi : [Lung Diffusion: A Review] Alfian Nur Rosyid; Isnin Anang Marhana
Jurnal Respirasi Vol. 4 No. 2 (2018): Mei 2018
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (804.205 KB) | DOI: 10.20473/jr.v4-I.2.2018.61-70

Abstract

Diffusion capacity is useful for measuring ability of pulmonary microcirculation to transfer oxygen and carbon dioxide from alveoli to capillaries. Physiological examination of diffusion is a continuation of physiological examination of ventilation. Diffusion capacity is measured by DLCO (Diffusing capacity for Carbon Monoxide). Measurement of oxygen diffusion capacity directly is very difficult so that indirect methods are used using carbonmonoxide (DLCO). Diffusion capacity of oxygen is equivalent to DLCO multiplied by 1.23. Normal value of DLCO is 20-30 ml/minute mmHg. Some factors that affect DLCO are Hb levels, COHb in smokers, and alveolar volume. Some techniques for measuring DLCO include Steady-state, Three-equation Single-breath, Nitrogen Washout, and Intra-breath DLCO. This test is indicated in pulmonary parenchymal disease (pulmonary fibrosis, asbestosis, sarcoidosis, interstitial lung disease), cystic fibrosis, pulmonary hypertension, and pulmonary bleeding. DLCO is increased in asthma patients, obesity, polycythemia, intraalveolar bleeding, and right-left heart shunting. DLCO is decreased in emphysematous lung patients, pulmonary post resection, bronchial obstruction, multiple pulmonary embolism, anemia, idiopathic pulmonary fibrosis, asbestosis, sarcoidosis, vascular collagen disease, hypersensitive pneumonitis, and alveolar proteinosis.
Back Matter Vol 6 No 2, 2020 Back Matter
Jurnal Respirasi Vol. 6 No. 2 (2020): May 2020
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (315.901 KB) | DOI: 10.20473/jr.v6-I.2.2020.%p

Abstract

Diagnosis and Outcome of Tuberculosis of Knee Joint (Gonitis Tuberculosis) with Pulmonary Tuberculosis after Completing Anti-Tuberculosis Therapy: A Case Report Anita Nur Charisma; Winariani Koesoemoprodjo
Jurnal Respirasi Vol. 7 No. 1 (2021): January 2021
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (543.426 KB) | DOI: 10.20473/jr.v7-I.1.2021.19-26

Abstract

Background: Tuberculosis (TB) in extra-pulmonary organs, such as bone and joint TB, has an incidence rate of 19% of the cases and represents 11-15% of all extra-pulmonary TB. The predilection of bones and joints is the most common predilection with more than 10% of the cases. Gonitis TB is a monoarthritis, chronic progressive, and intermittent disease. Hematogenous spreads through synovial or subchondral or as a focus in the juxta-articular bone. The spread can also occur indirectly from osseous lesions of the epiphyseal bone in adults or metaphysis in children, which causes erosion in the joint space and becomes arthritis.Case: A 19-year-old female with a chief complaint of swelling in the right knee joint accompanied by pain and difficulty in the legs to move and straighten the body. Another complaint was cough with whitish sputum, fever and night sweating, decreased appetite, and loss of body weight. Radiological chest X-ray showed fibro-infiltrates in both hemithoraces and radiological of the right genu, impression like joint effusion and mass density opacity in the popliteal, and suspicious abscess in the soft tissue. GeneXpert MTB/RIF examination of genu tissue and sputum: medium  Mycobacterium tuberculosis (M.Tb) was detected, rifampicin sensitive. Histopathology from the open biopsy showed the tissue consisted of epitheloid-shaped histiocyte cells forming granulomas. Ziehl Neelsen staining of the tissue obtained acid-fast bacillus (AFB).Conclussion: Gonitis TB is a hematogenous spread of M.Tb from infection with a deep primary focus on the joint that is chronic progressive and generally affects one joint. The management can be done by administering anti-tuberculosis and clinical monitoring.
Nilai Diagnostik Adenosine Deaminase (ADA) Cairan Pleura pada Penderita Efusi Pleura Tuberkulosi: [The Value of Adenosine Deaminase of Pleural Fluid in Tuberculosis Patient] Rizki Nur Amalia; Isnu Pradjoko
Jurnal Respirasi Vol. 2 No. 2 (2016): Mei 2016
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (181.968 KB) | DOI: 10.20473/jr.v2-I.2.2016.35-40

Abstract

Background: Tuberculosis pleural effusion is the most common extrapulmonary TB after lymphadenitis TB. Limited diagnostic methods make TB pleural effusion hard to diagnose. Adenosine deaminase ADA is an enzyme in purin catabolism process which catalyze adenosine into inosine and deoksiadenosine into deoksiinosin. This process is important in lymphoid cell differentiation. ADA is elevated in TB pleural effusion. Method: This study was a cross sectional analytic observational. Statistic analysis was using two independent samples T test. ROC curve was used to determine cut off value of ADA. Kappa test was used to determined the level of agreement of ADA cut off value. Results: Forty eight samples were included in this study, 18 samples with TB pleural effusion and 30 samples with non TB pleural effusion. There was significant difference between pleural fluid ADA in TB and non TB. Positivity of AFB sputum and MTB culture did not show any significant differences. Cut off ADA value for TB pleural effusion diagnosis was 39,19 with sensitivity 88,9% and spesificity 90%. Conclusion: Examination of ADA level in pleural fluid is a usefull tool to diagnose TB pleural effusion.
Manajemen Ekstravasasi Kemoterapi: [Extravasasion Chemoteraphy Management] Nur Nubli Julian Parade; Isnu Pradjoko
Jurnal Respirasi Vol. 5 No. 1 (2019): Januari 2019
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1468.389 KB) | DOI: 10.20473/jr.v5-I.1.2019.15-21

Abstract

Extravasation is a problem for patient receiving chemotherapy. This will cause pain, ulcer, necrosis and might be a permanent disability. Extravasation is a leakage of a fluid or medicine to the surrounding subcutaneous tissue of the vein or vascular, that may cause skin or tissue necrotic. There was a wide span of incidence data of extravasation on the literature, between  0,01% and 11% reported from child to adult. Management of extravasation was based on proper maintenance of the intravenous (IV) line and application of cold or warm compresses, plus the use of antidotes when available. Antidotes for extravasation that have been shown to be useful are sodium thiosulfate for nitrogen mustard, dimethylsulfoxide for anthracyclines and mitomycin, and hyaluronidase for the vinca alkaloids. New treatments include dexrazoxane, sargramostim, and hyperbaric oxygen for doxorubicin extravasations. In order to improve patient service  quality and reduce morbidity, every medical staff handle cancer patient receiving chemotherapy should have sufficient knowledge about how to manage extravasation event.
Cerebellar Tuberculoma in a Patient with Lung Tuberculosis New Case: A Case Report Gemilang Khusnurrokhman; Tutik Kusmiati
Jurnal Respirasi Vol. 6 No. 3 (2020): September 2020
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (266.979 KB) | DOI: 10.20473/jr.v6-I.3.2020.75-78

Abstract

Background: Tuberculosis (TB) is an infectious disease which can occur in the lungs and extra lung. One kind of extra lung TB is Cerebellum tuberculoma, which is one of rare manifestations form of TB, difficult to diagnosed, because sign and symptom is not specific.Case: A 17-year-old female presented a TB symptoms. She also had contact with her neighbor that was diagnosed with TB. In physical examination there was reduced motor function on her right extremities. Chest radiology revealed opacities in 2/3 superior in the left lung before treatment. Computed Tomography (CT) head scan with contrast showed ring contrast enhancement in left subcortical hemisphere cerebellum with size as 1.8 x 1.8 x 1.7 cm. Multiple lymphadenopathy in right-left upper-aid jugular and lymph node subcentimeter in right of submandibular, right-left lower jugular with varieties of size, the biggest is 1.6 x 1.5 cm. After 6 months treatment the tuberculoma of cerebellum was gone.  Conclusion:Cerebellum tuberculoma is a rare presentation of active TB. Radiological imaging plays an important role in the diagnosis and monitoring of the disease. The appereance of tuberculoma on our patient CT showed nodular-enhancing lesion. Intracranial tuberculoma should be treated conservatively, since the majority of these lesions resolve completely with Anti-Tuberculosis Drugs (ATD). Our patient started ATD and the lesions completely disappeared within 6 months. We wanted to present our case due to well-responded to ATD and being an example of atypical presentation of tuberculosis both clinically and radiologically. 
Back Matter Vol 4 No 3, 2018 Back Matter
Jurnal Respirasi Vol. 4 No. 3 (2018): September 2018
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (206.282 KB) | DOI: 10.20473/jr.v4-I.3.2018.%p

Abstract

TB MDR Primer dengan Limfadenitis TB pada Wanita SLE: [Primary Multidrug-Resistant Tuberculosis Mixed with Lymphadenitis Tuberculosis in a Woman with SLE] Ika Yunita Sari; Tutik Kusmiati
Jurnal Respirasi Vol. 1 No. 3 (2015): September 2015
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (292.684 KB) | DOI: 10.20473/jr.v1-I.3.2015.81-87

Abstract

Background: Primary resistance is the resistance that occurs in patients who have never received treatment OAT or had ever received  treatment OAT is less than 1 month. The incidence of primary MDR in Central Java in 2006 2.07%. Extrapulmonary TB about 15-20%  of all cases of TB, and TB lymphadenitis is the highest form (35% of all extrapulmonary TB). Patients with decreased immune systems  (SLE) can increase the incidence of TB. Research in Spain get 6x higher TB incidence in patients with SLE. Case: We present the case  of 19 year old woman SLE who received treatment for 11 months whose came with shortness of breath and chronic cough since 2 month  prior to admission. In physical examination we found right and left submandibula lymphonodi enlargement as solid, slightly mobile  nodule with diameter 3 cm. Chest X ray showed lung inflammation which suspicion of specific process and minimal left pleural effusion,  and concluded as pulmonary TB. FNAB confirmed lymphadenitis TB with granulomatous inflammation. One of AFB result is positive  and Gene Xpert is MTB positive with rifampicin resistant that make this patient categorized as primary MDR TB with lymphadenitis  TB. This patient received Pirazinamid 1500 mg, Ethambutol 800 mg, Kanamicin 750 mg, Levofloxacin 750 mg, Ethionamide 500 mg,  Cicloserin 500 mg, and B6 100 mg. Conclusion: MDR TB in general occur in patients with a history of OAT previous TB (MDR TB  secondary). Primary MDR TB with lymphadenitis tb is a rare case, but can occur on the condition that decreases the immune system,  one of SLE. This involves multiple immune disorders caused by the use of long-term immunosuppressive therapy. 
Front Matter Vol 3 No 1, 2017 Front Matter
Jurnal Respirasi Vol. 3 No. 1 (2017): Januari 2017
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (145.886 KB) | DOI: 10.20473/jr.v3-I.1.2017.%p

Abstract