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INDONESIA
Jurnal Respirasi (JR)
Published by Universitas Airlangga
ISSN : 24070831     EISSN : 26218372     DOI : -
Core Subject : Health,
Jurnal Respirasi is a National journal in accreditation process managed by Department of Pulmonology & Respiratory Medicine Faculty of Medicine Airlangga University - Dr. Soetomo General Hospital, Surabaya. Publish every January, May, September every year with each of 5 (five) complete texts in Indonesian.
Arjuna Subject : -
Articles 321 Documents
Seorang Laki-laki Usia 16 Tahun yang Mengalami Drowning dan Pneumotoraks Paska Pemasangan Ventilator Mekanik: [Pneumothorax in a Ventilated Young Man after Drowning: A Case Report] Ira Nurrasyidah; Winariani Koesoemoprodjo
Jurnal Respirasi Vol. 1 No. 1 (2015): Januari 2015
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (321.775 KB) | DOI: 10.20473/jr.v1-I.1.2015.15-21

Abstract

Background; Drowning is defined as respiratory impairment due to submersion/immersion in liquid. The liquid/air interface at the entrance of the airway prevents the victim from breathing air. According to the World Health Organization (WHO), 0.7% of all deaths worldwide - or more than 500,000 deaths each year - are due to unintentional drowning. Drowning is the second leading cause of unnatural death after road traffic injuries. Most of these deaths occur in countries with low or middle per capita income. Case; A16-years-old man rescued after drowning in the mud puddle for 15 minutes. He was unconscious, cyanosis, dyspnea and cough with blood and mud. After receiving oxygen in the nearest hospital he got conscious but still dyspnea. He came to our hospital and after undergone several examination we concluded that he had lung edema, ARDS and pneumonia aspiration. Patient immediately intubated and got mechanical ventilation. Five days later patient encounter pneumothorax on the right hemithorax, maybe due to barotrauma and we perfomed a chet tube insertion for three days. Patient had a good progression, there was no deficit neurologic and injury in the other organ. On follow up five months after patient hospitalized revealed normal condition on chest x ray.
Front Matter Vol 7 No 2, 2021 Front Matter
Jurnal Respirasi Vol. 7 No. 2 (2021): May 2021
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (695.356 KB) | DOI: 10.20473/jr.v7-I.2.2021.%p

Abstract

Pendekatan Terapi Asthma-COPD Overlap (ACO): [The Approach of Asthma-COPD Overlap Syndrome Treatment] Muhammad Amin; Alamsyah Sitepu
Jurnal Respirasi Vol. 3 No. 3 (2017): September 2017
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1458.147 KB) | DOI: 10.20473/jr.v3-I.3.2017.97-105

Abstract

Asthma and COPD are the most common chronic airways disease and have different clinical manifestations and treatments. Asthma is an airway inflammatory disease mediated by Th2 cytokines, CD4 + lymphocytes and eosinophils, whereas inflammation of COPD is affected by Th1 cytokines, CD8 + lymphocytes and neutrophils. Asthma-COPD overlap (ACO) is the presence of persistent airflow limitations with some symptoms resembling asthma and some other symptoms similar to COPD. Current treatment of ACO is to target the dominant inflammatory phenotype of eosinophils and neutrophils. Treatments given to patients with dominant eosinophil phenotype are inhaled and anti-IgE corticosteroids, and the drugs under reasearch are anti-IL-5, anti-IL-13, GATA3 inhibitors, anti-IL-33, anti-IL-25 and anti-thymic stromal lymphopoietin (anti-TSLP). Treatment given to patients with dominant neutrophil phenotype was macrolide, and treatment under reasearch was anti-IL-1, anti-IL-17A, anti-IL-23, CXCR2 antagonists, p38 MAPK inhibitor / JAK inhibitors and PDE4 inhibitors. Paucygranulocyte patient were given LAMA, LAMA + LABA therapy and bronchial thermoplasty. The therapy currently under study for this group is triple inhalation.
Perbandingan Pola Kuman dan Kadar Biomarker Inflamasi Penderita Severe Pneumonia dengan Penderita Non-severe Pneumonia : [Bacterial Pattern and Inflammatory Biomarker in Severe Pneumonia Compared to Non-Severe Pneumonia Patient] Daniel Maranatha; Mawardi Mawardi
Jurnal Respirasi Vol. 5 No. 2 (2019): Mei 2019
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (232.811 KB) | DOI: 10.20473/jr.v5-I.2.2019.29-33

Abstract

Background: Severe pneumonia is still a serious problem with high mortality rate. The cause of severe pneumonia due to high inflammation or different microbial pattern compared to non-severe pneumonia is still unknown. Methods: An analytic observational study with cross-sectional design was performed in patients with severe pneumonia and non-severe pneumonia treated in intensive care unit (ICU), intensive observation room (ROI), and all inpatient wards of Dr. Soetomo General Hospital Surabaya for a period of 1 year from September 2017 to September 2018. Patients with pneumonia accompanied by active pulmonary tuberculosis (TB), lung tumors, and acute infections other than pulmonary organs were excluded from this study. All study subjects were taken for sputum samples for aerobic sputum culture and blood samples for biomarker examination of C-reactive protein (CRP) and procalcitonin (PCT). Results: The total subjects were 64. Mean value of CRP and PCT levels severe pneumonia was 143.8 mg/L and PCT levels 23.1 ng/ml, respectively. Mean value of CRP and PCT levels non-severe pneumonia was 75.0 mg/L and PCT level 8.08 ng/ml, respectively. There was a significant difference in CRP and PCT levels of severe pneumonia and non-severe pneumonia patients (p < 0.05), whereas no meaningful difference in microbial patterns in both groups. Conclusion: Since inflammation responses of severe pneumonia were more massive than nonsevere patients, it will produce higher CRP and PCT levels.
Perubahan Fungsi Paru pada Usia Tua: [Lung Function Alteration in Geriatric Patients] Helmia Hasan; Rena Arusita Maranatha
Jurnal Respirasi Vol. 3 No. 2 (2017): Mei 2017
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (96.176 KB) | DOI: 10.20473/jr.v3-I.2.2017.52-57

Abstract

Aging causes many changes in biological processes characterized by progressive and widespread changes associated with increased susceptibility to various diseases. Aging is not a homogeneous process. In contrast, human organs aging at different rates are affected by several factors, including genetic factors, lifestyle, and environmental exposure. Healthy aging remains accompanied by some morphological and functional changes in the respiratory system. During the first two decades of life, the lungs undergo a phase of growth and maturation. Respiratory system achieves maximum function at the age of 20 years for women and 25 years for men. Throughout the rest of life, aging is associated with a progressive decline in pulmonary performance and function. The normal aging of the respiratory system is associated with structural and functional decline in the respiratory system, resulting in increased respiratory work compared to younger subjects and is associated with reduced reserves in cases of acute illness, such as heart failure, infection, or airway obstruction. Pulmonary function decreases slowly throughout life even in healthy people. Disabilities and diseases related to aging are a global problem due to the longevity of life expectancy. An increased proportion of the elderly population is a challenge for doctors because of the clinical complexity of the elderly. A better understanding of change can help diagnose and treat lung disease in the elderly population.
Allergic Reaction due to Anti-Tuberculosis Drugs, How to Manage? Nur Prasetyo Nugroho; Tutik Kusmiati
Jurnal Respirasi Vol. 7 No. 2 (2021): May 2021
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (377.555 KB) | DOI: 10.20473/jr.v7-I.2.2021.79-85

Abstract

Tuberculosis (TB) still becomes a significant health problem in Indonesia. The first-line anti-tuberculosis drug (ATD) is still the most effective TB drug, but it can have some side effects. One of them is allergic skin reactions that can affect a patient's compliance. Allergic reactions due to ATD are found in 4-6% of TB cases and are the third most frequent side effect after gastrointestinal and liver function disorder. All first-line ATD can cause allergic reactions. Allergic reactions due to ATD can be mild, such as itching and reddish rashes, to severe and life-threatening rashes, such as anaphylactic shock, Steven Johnson Syndrome (SJS), and Toxic Epidermal Necrotic (TEN). The most important things in the management are identifying and stopping drugs. It includes drug challenge and desensitization of causing drug. Desensitization must be distinguished from drug challenge or provocation tests, which are diagnostic tools. The proper management of ATD allergic reactions can improve compliance and patient's outcomes. 
Kepositifan Induksi Sputum NaCl 3% dan Teknik Broncho Alveolar Lavage pada Pneumocystis Pneumonia: [Positivity Result of Nebulized NaCl 3% versus Bronchoalveolar Lavage in Pneumocystis Pneumonia] Isnin Anang Marhana; Retna Dwi Puspitarini
Jurnal Respirasi Vol. 2 No. 3 (2016): September 2016
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (113.621 KB) | DOI: 10.20473/jr.v2-I.3.2016.69-75

Abstract

Background: Pneumocystis pneumonia (PCP) is a major cause of morbidity and mortality in patients immunocompromised. The incidence of PCP in HIV are 0.3 cases per 100 person years with mortality 63.6%. The diagnosis of PCP experiencing difficulties because of the causative organism can not be cultured. Several attempts were carried out to obtain a representative sample sputum through induced sputum and bronchoalveolar lavage. This study compared the use of induced sputum and bronchoalveolar lavage (BAL) in the diagnosis of PCP. Methods: From September, 2015, to February, 2016, HIV-positive patients 21 to 65 years old were evaluated at UPIPI ward, Soetomo hospital with suspicion of PCP based on clinical and radiological findings. Sputum induction and BAL was done for Giemsa staining. Result: Thirteen subjects with a mean age of 40, with 11 male (84.6%). All subjects with chief complain shortness of breath and common complain cough with hard to expetorate. Most frequent risk factors was freesex. Mean of subjects received treatment cotrimoxazole is 3.5 days. Six subjects have been treated with ART. Mean of LDH serum was 554.62 ± 376.707 U/l. Interstitial infiltrate was the most frequent radiological pattern (76.9%). Most bronchoscopy examinations showed normal results (84.6%). Both Giemsa staining from induced sputum and BAL showed no positive results. Conclusion: All Giemsa staining from both induced sputum and BAL can not be compared due to no positive result.
Pneumotoraks Bilateral dan Transaminitis Non Spesifik pada Silikosis: [Bilateral Pneumothorax and Transaminitis in Silicosis Patient: A Case Report] Sahrun Sahrun; Winariani Koesoemoprodjo; Ariani Permatasari
Jurnal Respirasi Vol. 4 No. 3 (2018): September 2018
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (529.871 KB) | DOI: 10.20473/jr.v4-I.3.2018.76-85

Abstract

Background: Silicosis is a fibrosis in the lung caused by inhalation, retention, and reaction to crystalline silica. The prevalence rate is potentially increasing throughout the world. Cases of bilateral spontaneous pneumothorax and transaminitis due to complications of silicosis are very rare. In this case, the patient was presented with bilateral secondary spontaneous pneumothorax as well as in the development of the diagnosis of silicosis, liver dysfunction, and pneumonia. Case: A 36-year-old male was admited to hospital with shortness of breath, the patient was once stone artisans for 7 years, rarely using PPE. Bilateral pneumothorax was established based on the results of clinical and radiological examinations. HRCT showed that it supported silicosis, left fluidopneumothorax, and right pneumothorax. Bronchoscopy was not possible due to the incompatible conditions and subsequently the patient was examined for silica levels from both plueral fluid with significant pleural silica. Summary: Diagnosis of pulmonary silicosis was done by clinical, radiological, and silica analysis of bronchial rinses, but certain conditions of silica could be found from pleural fluid. Silicosis therapy with complications until recently is only symptomatic, definitive therapy has not been found. Silicosis complications can be from pneumothorax bilateral (rarely), tuberculosis, transaminitis, and pneumonia. Conclusion: Pulmonary silicosis can be found from pleural fluid when the amount is large enough, fibrosis and extensive lung damage occurred. Silicosis can have an impact on pneumothorax, liver disorders, pneumonia, tuberculosis, and respiratory problems.
Back Matter Vol 1 No 2, 2015 Back Matter
Jurnal Respirasi Vol. 1 No. 2 (2015): Mei 2015
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (184.282 KB) | DOI: 10.20473/jr.v1-I.2.2015.%p

Abstract

Front Matter Vol 5 No 3, 2019 Front Matter
Jurnal Respirasi Vol. 5 No. 3 (2019): September 2019
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (135.66 KB) | DOI: 10.20473/jr.v5-I.3.2019.%p

Abstract