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Jurnal Respirasi (JR)

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Published by Universitas Airlangga

ISSN : 24070831 EISSN : 26218372 DOI : -

Core Subject : Health,

Health Professions Medicine & Pharmacology Public Health

Jurnal Respirasi is a National journal in accreditation process managed by Department of Pulmonology & Respiratory Medicine Faculty of Medicine Airlangga University - Dr. Soetomo General Hospital, Surabaya. Publish every January, May, September every year with each of 5 (five) complete texts in Indonesian.

Arjuna Subject : -

Articles 321 Documents

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Back Matter Vol 2 No 3, 2016 Back Matter
Jurnal Respirasi Vol. 2 No. 3 (2016): September 2016
Publisher : Faculty of Medicine Universitas Airlangga

Manajemen Pemberian Antibiotik dengan Hasil Uji Kepekaan Resisten: [Management of Antibiotics Use with Resistant Sensitivity Test Results] Deny Perdana Putra; Tutik Kusmiati
Jurnal Respirasi Vol. 1 No. 1 (2015): Januari 2015
Publisher : Faculty of Medicine Universitas Airlangga

The use of antibiotics in developed countries 13-37% and 30-80% in developing countries. Inappropriate use of antibiotics around 40-62%. There is a relationship between the use of antibiotics in bacterial resistance. Reported a man, 45 years old with a diagnosis of pneumonia + sepsis + DM Type 2 + hypoalbuminemia + anemia + suspek nephrotic syndrome. Empirical therapy is given Meropenem and Levofloxacin 1 750 3 1 grams milligrams. Evaluation after empirical therapy showed no improvement clinically and radiologically. The result of the patient ‘s sputum cultures of Pseudomonas aeruginosa which are resistant to antibiotics tested, therefore the definitive therapy can not be given based on antibiotic susceptibility. The cause of this multifactorial resistance in patients with Pseudomonas resistance to antibiotics through four mechanisms. Therefore, definitive therapy based on local patterns of bacteria and sensitivity test on pneumonia issued by the Department of Microbiology Clinic. Based on the data, antibiotic Piperacillin-tazobactam 4 4, 5 grams are then administered. The results of the evaluation of clinical, radiological and laboratory showed significant improvements in patients.

Metastasis Kanker Paru: [Lung Cancer Metastatic] Anna Febriani; Achmad Furqon
Jurnal Respirasi Vol. 4 No. 3 (2018): September 2018
Publisher : Faculty of Medicine Universitas Airlangga

Metastasis is the ability of cells to escape from the primary tumor, then enter the circulation to the distant tissue and form a secondary tumor. There are hemodynamic hypothesis (anatomical) and seed and soil hypothesis (molecular recognition). Tumor cells spread through several ways: percontinuitatum, lymphogen, hematogenous, transluminal, transcelomic, and iatrogenic. The stages of the metastasis process include: detachement, invasion, intravasation, circulation, extravasation, and angiogenesis. Predilection of lung cancer metastasis often happens in the brain, bones, liver, and adrenal glands. The spread of lung cancer metastasis to the brain, bone, and liver occurs hematogenously. Adrenal glands metastasis ipsilateral occurs lymphatically, while contralateral occurs hematogenously. Lung cancer is often diagnosed at an advanced stage, because in the early stage it is often asymptomatic. Metastasis of lung cancer to distant organs is the most cause of lung cancer deaths.

Front Matter Vol 1 No 2, 2015 Front Matter
Jurnal Respirasi Vol. 1 No. 2 (2015): Mei 2015
Publisher : Faculty of Medicine Universitas Airlangga

Aspirasi Jarum Pentul yang Tertanam 10 Hari di Bronkus Kanan Seorang Remaja: [Aspiration of Implanted Pin in the Right Bronchus of a Teenager for More than a Week: A Case Report] Isnu Pradjoko; Irmi Syafa’ah; Aries Subianto
Jurnal Respirasi Vol. 3 No. 2 (2017): Mei 2017
Publisher : Faculty of Medicine Universitas Airlangga

Background: Foreign bodies can come from outside the body (exogenous) and in the body (endogenous). Foreign bodies can cause total obstruction resulting in atelectasis or partial obstruction with emphysema. Case: A 14-year-old girl with a cough with phlegm mixed with blood spots one day before admission. Patients swallowed needle 10 days ago while wearing jilbab while joking at school. Chest X-rays appear density of a metal with a long straight form of about 3.5 cm projected in the lower right hemitorac. Discussion: Performed Fiber Optic Bronchoscopy (FOB) with diagnostic and therapeutic indications for picking up foreign objects. In patients there is minimal bleeding post extraction pentul needle. Bleeding can be overcome by administering a cold sterile NaCl solution to the airway. Thoracotomy is not performed on the patient because the needle can be taken using FOB. Conclusion: Foreign bodies of the airways can be harmful. The needle extraction using FOB can rule out the need for thoracotomy in patients.

Correlation between FEV1% Predicted and Blood Eosinophils in Patients with Exacerbations of Chronic Obstructive Pulmonary Disease (COPD) Alfian Nurfaizi; Isnin Anang Marhana; Gadis Meinar Sari; Arief Bakhtiar
Jurnal Respirasi Vol. 7 No. 2 (2021): May 2021
Publisher : Faculty of Medicine Universitas Airlangga

Introduction: Chronic obstructive pulmonary disease (COPD) exacerbations are still the leading causes of mortality. Eosinophil counts were recommended in assessing the risk of exacerbations. This additional examination was preferred rather than the pulmonary function test (PFT), which was considered less precise and had vast differences. Therefore, an analysis of the correlation between the FEV1% predicted and blood eosinophil counts were needed as a reference in the diagnosis of COPD exacerbation. This study aimed to determine the correlation between FEV1% predicted and blood eosinophils counts in patients with COPD exacerbations.Methods: This was a retrospective cross-sectional study by analyzing medical records of patients with COPD exacerbations at Dr. Soetomo General Hospital, Surabaya, from 2017 to 2018.Results: The characteristics of patients with exacerbations of COPD consisted of 91.7% male patients. Most of them were in the age group of 61-70 years old, 58.3% were in the private sector, 75% had a high school diploma, and 41.7% had normal body mass index (BMI). The percentage of the FEV1% predicted is directly proportional to the percentage of blood eosinophils with weak and statistically insignificant strength.Conclusion: The FEV1% predicted and blood eosinophil counts had a very weak correlation and statistically insignificant strength. Thus, it could not be used as a reference for diagnosis using one of the variables. Further research is needed with sputum eosinophils and biopsy as consideration for more accurate results.

Peran Imunitas Mukosa terhadap Infeksi Mycobacterium Tuberculosis: [The Role of Mucosal Immunity in Mycobacterium tuberculosis Infection] Irmi Syafa’ah; Resti Yudhawati
Jurnal Respirasi Vol. 2 No. 2 (2016): Mei 2016
Publisher : Faculty of Medicine Universitas Airlangga

Tuberculosis (TB) is one of major health problems in the world, with high morbidity and mortality rates. According to Global Tuberculosis Report 2015, Indonesia ranks as country with the 2nd highest number of TB cases in the world. Airway was described as a ‘gateway’ to the main pathogens, allergens and particles from the external environment. It has surveillance function that filtering beneficial and non-beneficial antigens, including Mycobacterium tuberculosis (MTB) as the causative agent of TB. MTB is a mucosal transmitted pathogen, infects human through mucosal tissue of respiratory tract. Airway mucosa was considered as the first barrier as well as inductive sites to initiate mucosal immune response against MTB. In this literature, the role of mucosal immune system, in this case especially airway mucosa, and its role against Mycobacterium tuberculosis infection in humans will be further discussed.

Triple Mutation Epidermal Growth Factor Receptor (EGFR) Exon 18 (G719S), 20 (T790M) and 21 (L858R) in a Male Patient with Lung Adenocarcinoma: A Case Report Nur Marleta Riza; Daniel Maranatha
Jurnal Respirasi Vol. 6 No. 1 (2020): January 2020
Publisher : Faculty of Medicine Universitas Airlangga

Background: Lung cancer is one of the deadliest cancers in the world. The percentage of non small cell lung cancer (NSCLC) is about 80% of the incidence of lung cancer. The type of NSCLC, adenocarcinoma, is usually found in the presence of epidermal growth factor receptor (EGFR) mutations.Case. A male patient aged 70 years, an active smoker, works as a farmer. He has complained of shortness of breath, and chest pain for three months. There was no family history of suffering from malignancy. The cytology result of the right pleural fluid indicated adenocarcinoma. He was diagnosed with pulmonary adenocarcinoma (D) stage IV positive mutation of EGFR exon 18 (G719S), 20 (T790M) and 21 (L858R) carnofsky score 70. He could survive for more than 11 months with the treatment of EGFR TKI, and received a good therapeutic response. Initially, for the first six months it was such a progressive disease, and for the next eleven months it became stable.Conclusion: In addition to the exon mutations found in this case, the cells in the tumor will continue to grow and develop into new mutants that are immune such drugs and rapidly split themselves into new, different forms. The therapy for complex mutations is still being developed. EGFR TKI therapy in this patient had a relatively good response. Further understanding of the molecular biology of lung cancer is seriously required.

The First Case of COVID-19 in South Kalimantan Muhammad Nor; Haryati Haryati
Jurnal Respirasi Vol. 6 No. 3 (2020): September 2020
Publisher : Faculty of Medicine Universitas Airlangga

Background: In December 2019, a series of acute respiratory syndromes occurred in Wuhan, China. This syndrome became known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The sudden appearance and rapid global spread of SARS-CoV-2 led World Health Organization (WHO) to declare it as a pandemic disease on March 11, 2020. We will report the first case COVID-19 in South Kalimantan.Case: A 44-year-old man was presented with fever, 7 days before admission. The patient also complained about cough with white phlegm and shortness of breath, accompanied by nausea with heartburn and decreased of appetite. He confessed that he just returned from local transmission areas of COVID-19. From physical examination, it was found SaO2 92% room air with bronchial sounds and ronchi in the lung. Chest X-ray showed peripheral infiltrates and diagnostic swab with RT-PCR in the oropharynx and nasopharynx showed that the patient was infected with SARS-CoV-2. HbsAg marker on this patient was also reactive. The patient then received supportive therapy as well as antiviral therapy. After 10 days of treatment, the patient was already free from the symptom, but swab evaluation remained positive. On the 31st day of treatment, the patient was finally declared cured with a negative swab result.Conclusion: The number of COVID-19 cases has increased from time to time. Holistic treatment and rapid detection greatly affect the prognosis of this disease. Prevention through health protocols is also very important to reduce its spread.

Front Matter Vol 5 No 2, 2019 Front Matter
Jurnal Respirasi Vol. 5 No. 2 (2019): Mei 2019
Publisher : Faculty of Medicine Universitas Airlangga

Page 12 of 33 | Total Record : 321

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Jawa timur

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Editorial Address Jl. Mayjen Prof. Dr. Moestopo 6-8 Surabaya 60286 Indonesia

Location Kota surabaya, Jawa timur INDONESIA

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respirasi@journal.unair.ac.id

Editorial Address
Jl. Mayjen Prof. Dr. Moestopo 6-8 Surabaya 60286 Indonesia

Location
Kota surabaya,

Jawa timur

INDONESIA