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Medica Hospitalia
Published by RSUP Dr. Kariadi Semarang
ISSN : 23014369     EISSN : 26857898     DOI : https://doi.org/10.36408/mhjcm
Core Subject : Health,
Dentistry Health Professions Medicine & Pharmacology Nursing Public Health
Medica Hospitalia: Journal of Clinical Medicine adalah jurnal ilmiah yang diterbitkan RSUP Dr. Kariadi dan menerima artikel ilmiah dalam bahasa Indonesia dan bahasa Inggris yang diharapkan dapat menjadi media untuk menyampaikan temuan dan inovasi ilmiah dibidang kedokteran atau kesehatan kepada para praktisi dan akedemisi di bidang kesehatan dan kedokteran.
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Articles 584 Documents
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The Relationship between the Duration of Suffering from Diabetes and HbA1c Levels with the Degree of Liver Stiffness in Type 2 Diabetes Mellitus Patients Faza Khilwan Amna; Maya Nuriya Widyasari; Hery Djagat Purnomo; Frederica Mardiana Wahyuni; Bambang Satoto; Hermina Sukmaningtyas
Medica Hospitalia : Journal of Clinical Medicine Vol. 11 No. 1 (2024): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36408/mhjcm.v11i1.1011

Abstract

BACKGROUND : Type 2 diabetes mellitus (DM) is one of the major problems faced by the health system. Diabetes is a multifactorial, chronic and progressive metabolic disorder characterized by chronic hyperglycemia. Persistent hyperglycemia is associated with long-term damage to the  liver. Ultrasound elastography is one of imaging modality that can assess liver stiffness, thus can assist clinicians in determining therapy, evaluating, and predicting disease progression. AIMS :  Aim of this study was to determine the relationship between liver stiffness degree by using ultrasound elastography with the duration of T2DM and HbA1c levels. METHOD : This study was an observational analytic research with a cross-sectional approach which carried out from May to September 2022 at the radiology department of Dr. Kariadi Hospital Semarang. Fifty subjects were included in this study and Rank-Spearman correlation test was used to analyze the relationship between liver stiffness degree with T2DM duration and HbA1c levels. RESULT :  Using ultrasonography elastography, the liver stiffness average was 7.92 + 6.72 kPa. The average of HbA1c levels was 8.55 + 2.63%. T2DM duration average was 9.10 + 6.50 years.   The rank-spearman test showed a significant correlation between HbA1c levels and the degree of liver stiffness (p = 0.000) with a correlation coefficient (r) of 0.68. There was no significant correlation between the T2DM duration and the degree of liver stiffness (p = 0.052). CONCLUSION : There was a significant correlation between liver stiffness and HbA1c levels, but there is no correlation between liver stiffness and T2DM duration
The Effect of Mckenzie Exercise to Increase Craniovertebral Angle in Forward Head Posture of Adolescent Raras Hestina Laksmi; Nitaya Putri Nur Hidayati; Yuliana Ratmawati
Medica Hospitalia : Journal of Clinical Medicine Vol. 11 No. 1 (2024): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36408/mhjcm.v11i1.1013

Abstract

BACKGROUND : adolescents with low physical activity and smartphone addiction has been indicated to reduced the craniovertebral angle, there by causing a forward head posture and increasing scapular dyskinesis, characterized by a craniovertebral angle (CVA) less than 50o. McKenzie is one of exercise that can helm correct posture in forward head posture AIMS : to determine the effect of the McKenzie exercise on increasing the craniovertebral angle in the forward head posture of adolescents. METHOD : students of MAN 1 Surakarta (Islamic Boarding School) with advanced head posture, aged 14-17 years using a simple random sampling technique divided into group I as the intervention group (n=16) and group II as the control group (n=14). Group I was given treatment of McKenzie exercise 3 times a week for 4 weeks, and the control group was not given any treatment. The Craniovertebral angle were assessed using photo analysis with Image-J application. RESULT : The results of the study indicate that the characteristics of respondents according to age are mostly 16 years old. The mean NDI score in the intervention group was 23,63 and the mean NDI score in the control group was 24,60. The results of statistical test using independent samples test showed that there was a significant difference during the intervention and the control group (p=0,000) CONCLUSION : McKenzie's exercise can affect to increasing the craniovertebral angle in the forward head posture of adolescents.
The Influence of inflammatory factors (IL-6, CRP, NLPR, D-Dimer, LDH) on the PaO2/FiO2 ratio, in patients with severe and critical degrees of COVID-19 Harnoto, Yulia Octaviany; Assagaf, Ali; Pratiwi, Dewi Indah Noviana; Isa, Mohamad; Nurrasyidah, Ira; Kusumawardhani, Erna
Medica Hospitalia : Journal of Clinical Medicine Vol. 10 No. 3 (2023): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36408/mhjcm.v10i3.1014

Abstract

BACKGROUND: Several types of inflammatory biomarkers that are important in severe and critical Covid-19 infections include: levels of IL-6, C-reactive protein (CRP), lactate dehydrogenase (LDH), D-Dimer and neutrophil-lymphocyte platelet ratio (NLRP), which are independent variables. Meanwhile, the severity of Covid-19 infection can be determined by measuring the PaO2 /FiO2 ratio. However, the relationship between the PaO2/FiO2 ratio as the dependent variable is not yet known. AIMS: To analyze the relationship between PaO2/FiO2 ratio and inflammatory biomarkers in COVID-19 patients METHOD: An analytic observational study with a retrospective, cross-sectional approach. The research sample consisted of PCR-confirmed severe and critical COVID-19 patients who were treated in the isolation room of the Ulin Hospital in Banjarmasin from August–December 2021, who met the inclusion and exclusion criteria. Data analysis used the Spearman test to see the relationship between the PaO2/FiO2 ratio and various inflammatory markers. RESULT: 52 severe and critical patients were observed according to the research flow. The number of male and female subjects (32/20) was found. The mean age was 55.38 years. The correlation test found that: there was no significant relationship between the PaO2/FiO2 ratio and IL-6 (p = 0.964), but there was a negative correlation between the PaO2/FiO2 ratio and: a).CRP (p = 0.038), b).LDH ( p<0.001), c).NLPR (p = 0.013), and d). D-dimer (p<0.001). The inflammatory biomarkers NLPR, LDH, and D-dimer are important independent variables for the severity of COVID-19, namely the PaO2/FiO2 ratio. CONCLUSION: There are a significant correlation between the PaO2/FiO2 ratio to measure the severity of Covid-19 and several inflammatory biomarkers CRP, LDH, NLPR and D-dimer  
Differences In Effectiveness Between Progressive Muscle Relaxation Therapy And Slow Deep Breathing Therapy On Elderly Sleep Quality Wajihahni Rodiyah; Bintang Tatius; Novita Sari Dewi
Medica Hospitalia : Journal of Clinical Medicine Vol. 11 No. 2 (2024): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36408/mhjcm.v11i2.1015

Abstract

Background Every individual has a lifetime, starting from the womb, born into the world, to becoming elderly. Aging is a process of gradual loss of tissue's ability to repair itself, maintain its normal structure and function so that it cannot defend the tissue from injury (including infection), and repair the damage that occurs. In the elderly, there are various kinds of health problems such as sleep disorders. Sleep disorder or insomnia is a person's inability to sleep. Poor sleep quality can be improved in various ways such as relaxation techniques. Aim To compare the effectiveness of Jacobson's Progressive Muscle Relaxation (JPMR) and Slow Deep Breathing Therapy in improving sleep quality in the elderly. Method This type of research was a quantitative quasi-experiment with pretest and post-test methods (one group pre-test and post-test design). Respondents involved 49 people while research data were processed with the Mann-Whitney and Wilcoxon tests. The Sleep Quality Questionnaire used the PSQI questionnaire. Result The Wilcoxon test with an alternative to the Mann-Whitney test showed no significant difference in effectiveness between the two therapies with p-value = 0.274. Conclusion Both therapies had almost the same level of effectiveness; there was no significant difference between the two, so progressive muscle relaxation therapy and Slow Deep Breathing were equally effective in treating anxiety and improving sleep quality.
The Effectiveness Of E-Backnshou Exercise To The Improvement Of Neck, Shoulder And Back Pain In Computer Vision Syndrome Patient Hari Peni Julianti; Trilaksana Nugroho; Tanti Ajoe Kesoema; Neni Susilaningsih; Fifin Luthfia Rahmi; Maharani Prizka Pritadesya
Medica Hospitalia : Journal of Clinical Medicine Vol. 11 No. 1 (2024): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36408/mhjcm.v11i1.1017

Abstract

BACKGROUND : Extra-ocular complaints of Computer Vision Syndrome (CVS) are neck, shoulder, back pain.  The 20-20-20 rule and E-BACKNSHOU exercise are expected to improve accommodative mechanisms, ocular surface of the eye and extra ocular symptoms of CVS. AIMS :  Proving the effectiveness of E-BACKNSHOU exercise for the improvement of neck, shoulder and back pain in CVS patient. METHOD : The research design was Pre-Post Test with Control Design. Subjects were 30 medical students of Faculty of Medicine, Diponegoro University, Semarang, Indonesia who experienced CVS and neck, shoulder and back pain. The treatment group got the 20-20-20 rule and E-BACKNSHOU exercise and the control group got the 20-20-20 rule for 1 month. Pain was measured by Visual Analogue Scale (VAS). Statistical test was conducted using paired t-test, unpaired t-test and chi square. Value of significance p<0.05. RESULT :  There were significant differences in VAS score of neck, shoulder, upper back pain (p=0.00), and low back pain (p=0.022) before and after the intervention in the treatment group and VAS score of neck (p=0,002), shoulder (p=0.020), upper back (p=0.011), and low back pain (p=0.019) in the control group. Delta VAS score of the treatment group was greater than the control group and there was a significant difference in delta VAS score of shoulder pain (p=0,030), but there were no significant differences in delta VAS score of neck (p=0,934), upper back (p=0,356), and low back pain (p=0,150). CONCLUSION : The effectiveness of 20-20-20 rule and E-BACKNSHOU exercise is better than the 20-20-20 rule alone on treating neck, shoulder and back pain in CVS patient.
Rare case of of Enlargment dextro Inguinal Endometriosis TissueLump : Case Report and Literature review Susianto, Indra Adi; Hartono, Edward; Riyadi, Barkah Fajar; Amarwati, Siti; Kristanti, Alberta Widya; Mandagie, Aprilia Karen; Haekal, Mohammad
Medica Hospitalia : Journal of Clinical Medicine Vol. 10 No. 3 (2023): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36408/mhjcm.v10i3.1019

Abstract

Background : Endometriosis is usually found in intrapelvic structures such as the ovaries, peritoneum, gynecological organs and the pouch of Douglas. We report an unusual case of endometriosis in the  right  inguinal region. Cases : A 36-year-old woman with a history of laparoscopic surgery for endometriosis 4 years ago complained of catamenial pain and a mass in the  right  inguinal region, and her symptoms fluctuated with the menstrual cycle. An indistinct firm mass palpable in the  right  inguinal region. Ultrasound examination revealed a 2 × 1 cm mass in front of the pubic area on the lower edge of the rectus abdominis muscle. In a patient with an inguinal subcutaneous mass who complains of periodic changes in symptoms, endometriosis should be considered in the differential diagnosis. Conclusion : The low incidence of inguinal endometriosis is one of the considerations in the different diagnosis of painful inguinal hernias in the inguinal area in women with childbearing age. The diagnosis of endometriosis can be demonstrated clearly on High-Definition Ultrasound by trained personnel. Surgery is the optional treatment and is curative in this case.
Rehabilitation of A Child with Low Endurance in the Recovery Phase of Guillain-Barré Syndrome Budiati Laksmitasari; Johanes Putra; Luh Karunia Wahyuni; Rizky Kusuma Wardhani
Medica Hospitalia : Journal of Clinical Medicine Vol. 11 No. 1 (2024): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36408/mhjcm.v11i1.1020

Abstract

BACKGROUND: Guillain-Barré Syndrome (GBS) usually has a good prognosis of recovery. However, some patients can have remaining disabilities due to low cardiorespiratory fitness or endurance and needs to be managed. AIMS: This study reports the rehabilitation assessment and management of a child with low cardiorespiratory endurance in the recovery phase of GBS. CASE: A 12-year-old girl with a history of hospitalization due to Acute Motor and Sensory Axonal Neuropathy (AMSAN)-type of GBS was referred to the Physical Medicine and Rehabilitation (PMR) outpatient clinic with tiredness that restricted her school participation. She had low cardiorespiratory endurance, which was confirmed by a six-minute walk test (6-MWT). After the rehabilitation program, her endurance level was increased, and she can return to school. DISCUSSION: A comprehensive assessment showed that the muscle weakness, accompanied by obesity, anemia, and inactivity, led to low cardiorespiratory endurance that restricted the activity and participation. A rehabilitation program that consisted of aerobic and strengthening exercises improved cardiorespiratory endurance, walking ability, and school participation. CONCLUSION: Rehabilitation management in children with low cardiorespiratory endurance due to the sub-acute phase of GBS could help them regain their activity and participation during the recovery phase.
Effectiveness of Kelly Plication Method on Clinical Improvement in Stress Urinary Incontinence Patients Puspitasari Notohatmodjo; Besari Adi Pramono; Inu Mulyantoro; Herman Kristanto; Dewi Astri Purnaningtyas; Arufiadi Anityo Mochtar; Erwinanto Mulyantoro
Medica Hospitalia : Journal of Clinical Medicine Vol. 11 No. 1 (2024): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36408/mhjcm.v11i1.1032

Abstract

BACKGROUND: Patients with pelvic organ prolapse (POP) usually present with POP, but stress urinary incontinence (SUI) is also found during history taking and physical examination. As a result, the complaint of SUI is persistent despite POP surgery. Therefore, SUI found along with POP and undergoing surgery can be performed Kelly plication method. OBJECTIVES: To examine the effectiveness of Kelly's plication method on clinical changes and quality of life of patients suffering from SUI. METHODS: A single cohort prospective one-group pretest-posttest design conducted at RSUP Dr. Kariadi Teaching Hospital Semarang involving 31 research subjects. All subjects were measured preoperative IIQ-7 questionnaire and pad test. Then, all subjects will undergo Kelly method surgery. Postoperative evaluation will be conducted 3 months later, including measurement of the IIQ-7 questionnaire and pad test. All data will be analyzed with univariate and bivariate analysis using paired t-test and Wilcoxon test. RESULTS:  The effectiveness rate of Kelly's plication method was 58.06% in this study. Most of the subjects were aged 50-59 (38.7%) years and had experienced menopause (87.1%). Correlation analysis of baseline data on the degree of preoperative SUI showed that the degree of POP correlated SUI. The Pad test and IIQ-7 questionnaire test showed a significant decrease in postoperative measurements in the treatment group (p: <0.001 & p: <0.001). CONCLUSIONS: Kelly's plication method is effective in treating SUI.
The Correlation between Volatile Organic Compounds (VOC) with Leukotriene B4 and Eosinophil Counts in Chronic Obstructive Pulmonary Disease Patients Andrew Santosa; Ngakan Putu Parsama Putra; Aditya Sri Listyoko; Arinto Yudi Ponco Wardoyo; Nanik Setijowati
Medica Hospitalia : Journal of Clinical Medicine Vol. 11 No. 1 (2024): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36408/mhjcm.v11i1.1035

Abstract

BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a progressive respiratory disorder characterized by increasing Leukotriene B4 (LTB4) and eosinophil counts. Volatile organic compounds (VOCs) have shown promise as non-invasive biomarkers, reflecting COPD pathophysiology. Identifying specific VOCs associated with increased LTB4 and eosinophil counts could lead to the discovery of potential biomarkers for COPD severity or progression. AIMS: This study aims to investigate the correlation between VOCs and leukotriene B4 (LTB4) levels, as well as eosinophil counts counts in COPD patients. METHOD: Using an observational-analytic method with a case-control approach, 20 COPD patients and 20 controls were enrolled from the respiratory outpatient department of Dr. Saiful Anwar General Hospital, Malang. VOC levels were measured using a breath analyzer, while LTB4 levels were determined through enzyme-linked immunosorbent assays. Spearman’s correlation tests examined associations between VOCs, LTB4, eosinophil counts, and comorbidity, with Mann-Whitney tests comparing results against the control group. Data significance was set at p < 0.05. RESULT: There were 40 COPD patients and 40 controls in this study. There were significant differences between VOCs in the COPD group and the control group (p < 0.05). LTB4 level significantly increased in the COPD group than in the control group (p < 0.001), and there was no difference in the eosinophil level. There was a correlation between LTB4 and VOC level of C2H5OH in COPD patients (p = 0.009; r = 0.410). There was no correlation between eosinophil counts and VOCs (p = 0.939). The level of VOCs was significantly different between patients with only COPD and patients with COPD and comorbid lung cancer (p < 0.05). CONCLUSION: There is a correlation between VOC and LTB4 in COPD patients.
Prenatal, Perinatal And Postnatal Risk Factors From Mother And Child To The Incidence Of Epilepsy Susan Megawati Sibuea; Endang Kustiowati; Maria Immaculata Widiastuti Samekto; Dodik Tugasworo; Aris Catur Bintoro; Elta Diah Pasmanasari
Medica Hospitalia : Journal of Clinical Medicine Vol. 11 No. 1 (2024): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36408/mhjcm.v11i1.1042

Abstract

BACKGROUND: Epilepsy is a health problem that affects sufferers and their families, characterized by at least two seizures without provocation with an interval of more than 24 hours between seizures, one seizure without provocation with the possibility of recurring within 10 years, a diagnosis of epilepsy syndrome has been established. The risk of epilepsy can be influenced by the condition of the mother and child in the prenatal, perinatal and postnatal periods. AIMS: This study analyzed the risks of several prenatal, perinatal, and postnatal factors of mother and child as risk factors for epilepsy incidence. METHOD: A case control study was conducted at RSUP Dr. Kariadi Semarang from July 2022 to March 2023. A total of 90 eligible subjects  were divided into 45 case with epilepsy and 45 control with a non-epileptic diagnosis. Inclusion criteria were aged over 17 years to 40 years and exclusion criteria were subjects with mothers who had died or could not be interviewed, data were incomplete and had structural brain disorders or other diseases with clinical symptoms of seizures for the control group. The data obtained were analyzed  using chi squares test for bivariate association, followed by multivariate analysis with multiple logistic regression. RESULT: Maternal age during pregnancy (p=0.016), low birth weight (p=0.007), surgical birth (p=0.004), head trauma at the age of less than 6 years (p=0.008) have been shown to influence the occurrence of epilepsy with significance respectively. CONCLUSION: Prenatal factors of the mother which is maternal age during pregnancy, perinatal and postnatal factors of the child which are low birth weight, surgical birth, and head trauma at the age of less than 6 years are risk factors that influence the occurrence of adulthood epilepsy.

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