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JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Published by Universitas Airlangga
ISSN : 19073623     EISSN : 26849453     DOI : -
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health
Juxta (Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga) is a scientific peer-reviewed medical doctor which relevant to a medical doctor and other health-related professions by the Faculty of Medicine Universitas Airlangga, Indonesia. Juxta provides a forum for original article to the editor and it will be published Two-times a year. Studies that focus on evaluating and understanding the complex medical importance are welcomed in Juxta.
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Articles 193 Documents
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Characteristics of Patients with Abnormal Scars Managed at a Tertiary Hospital in Indonesia: A Descriptive Study Shafira Irmalia; David Sontani Perdanakusuma; Dwi Murtiastutik
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 17 No. 1 (2026): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/juxta.V17I12026.28-34

Abstract

Highlights: Burn scars were the leading cause of abnormal scars. Surgery was the primary treatment for abnormal scars.   Abstract Introduction: Human skin is prone to damage, resulting in abnormal scarring that can adversely affect individuals and society. This study aimed to examine the frequency, characteristics, and treatment options of patients with abnormal scars treated at Dr. Soetomo General Academic Hospital, Surabaya, Indonesia, from 2019 to 2023. Methods: This was a descriptive retrospective study that utilized 48 medical records of patients with abnormal scars at the Department of Plastic Reconstructive and Aesthetic Surgery, Dr. Soetomo General Academic Hospital, Surabaya, Indonesia, from 2019 to 2023. Data analysis was performed using the International Business Machines Corporation (IBM) Statistical Package for the Social Sciences (SPSS) for Windows version 25.0. The variables in this study included demographic characteristics, etiology of the scar, region, size, and management of abnormal scars. Results: Of 48 patients, the highest incidence was in 2023 (29.2%). The majority of patients were female (60.4%) and aged 15-49 years old (41.7%). Burns were the primary etiology of scars (35.4%), and most scars measured over 20 cm² (34.5%). Surgical treatment was the most common management option (54.7%). Conclusion: Patients with abnormal scars are most frequently affected by burn scars. A significant proportion of these individuals present with extensive hypertrophic keloid scars, for which surgical intervention is the most often used therapeutic method.
Attitude towards Blended Learning, Stress Levels, and Academic Procrastination Behavior: A Cross-Sectional Study Rania Azaria Triswiandi; Agneta Irmarahayu; Nunuk Nugrohowati; Hikmah Muktamiroh
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 17 No. 1 (2026): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/juxta.V17I12026.35-41

Abstract

Highlights: Academic procrastination can affect the quality of education. Normal stress reduces the likelihood of procrastination by 78% compared to very severe stress.   Abstract Introduction: Academic procrastination is the tendency to postpone academic work and is almost always associated with anxiety, which can adversely affect academic performance. This study aimed to determine the relationships between attitudes towards blended learning, stress levels, and academic procrastination behavior among medical students. Methods: This study employed an observational, analytical approach with a cross-sectional design and proportional stratified random sampling. The sample of this study comprised 229 students across 3 batches. The research instrument included an attitude questionnaire on blended learning, the Depression, Anxiety, and Stress Scale-21 Items (DASS-21), and an academic procrastination scale. The statistical tests used for bivariate analysis were the Chi-square and Kruskal-Wallis tests, with p-values reported. Multivariate analysis used ordinal logistic regression. Results: The bivariate test showed that the p-value for the association between attitudes towards blended learning and academic procrastination behavior was 0.612, and the p-value for the association between stress levels and academic procrastination behavior was 0.002. The multivariate test showed that normal stress reduced the likelihood of procrastination by 78% compared to very severe stress. There was no relationship between attitudes towards blended learning and academic procrastination, but there was a relationship between stress levels and academic procrastination. Conclusion: Attitudes towards blended learning did not affect academic procrastination behavior, while normal stress reduced the likelihood of procrastination compared to very severe stress.
Cost-Effectiveness Analysis of Taxane-Based and Anthracycline-Based Chemotherapy in Stage 4 Breast Cancer Patients at Dr. Soetomo General Hospital, Surabaya, Indonesia Adele Sabrina; Abdul Khairul Rizki Purba; Azril Okta Ardhiansyah; Annette d’Arqom
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 17 No. 1 (2026): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/juxta.V17I12026.42-47

Abstract

Highlights: Epirubicin (anthracycline-based) showed the highest cost-effectiveness. Taxane-based regimens were less cost-effective compared with anthracyclines.   Abstract Introduction: Breast cancer, particularly stage 4, contributes significantly to global morbidity and mortality. Anthracycline- and taxane-based chemotherapies are commonly used for metastatic breast cancer, but their high costs necessitate a cost-effectiveness analysis to inform healthcare financing. This study aimed to assess the cost-effectiveness of these therapies for patients with stage 4 breast cancer at Dr. Soetomo General Hospital, Surabaya. Methods: A retrospective review of medical records from 124 stage 4 breast cancer patients treated in inpatient and outpatient settings was conducted. Effectiveness rates and cost data for epirubicin, doxorubicin, docetaxel, and paclitaxel were analyzed. Data processing involved basic calculations in Google Sheets, and the average cost-effectiveness ratio (ACER) and incremental cost-effectiveness ratio (ICER) were calculated. Ethical clearance was obtained. Results: Epirubicin was the most cost-effective, with an ACER of 958,878 Indonesian Rupiah (IDR) and an ICER of -IDR 2,603,667. Conclusion: Epirubicin is the most cost-effective chemotherapy option for stage 4 breast cancer, supporting its use in resource-limited settings and guiding cancer therapy decisions.
Dermatome Distributions in Herpes Zoster Patients at Dermatology and Venereology Outpatient Clinic, Dr. Soetomo General Academic Hospital, Surabaya, Indonesia, in 2012-2014 Dara Sabrina; Trisiswati Indranarum; Subur Prajitno
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 17 No. 1 (2026): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/juxta.V17I12026.48-54

Abstract

Highlights: Various distributions of dermatomes in HZ patients and the correlations between dermatomes and the history of other diseases. There was a correlation between dermatome location and hypertension as a comorbid disease in HZ patients.   Abstract Introduction: Herpes zoster (HZ) can occur when the varicella-zoster virus, which infects the spinal nerves and causes dermatomal injury, reactivates in individuals who have previously had varicella and have healed. This study aimed to identify the risk factors and clinical consequences of HZ among patients at the Dermatology and Venereology Outpatient Clinic, Dr. Soetomo General Academic Hospital, Surabaya, Indonesia, from 2012 to 2014, in order to support the development of improved preventive strategies and reduce the prevalence of HZ. Methods: This retrospective study used the medical records of 138 HZ patients (n=138). This study employed both descriptive and analytical research methods. The Chi-Square and Fisher’s Exact tests were used in the bivariate analysis. The International Business Machines Corporation (IBM) Statistical Package for the Social Sciences (SPSS) version 24.0 was used to analyze the results, which were displayed as tables and charts. Results: Of 138 HZ patients, none had complications. Symptoms of HZ, which were more common among females aged 51 to 60 years old, included burning and pain in the left part of the body (40.58%) and the thoracic dermatome (41%). Most efflorescence (37.2%) belonged to grouped vesicles. Most other disease histories were varicella (53.49%). Correlation test results indicated that dermatome location, sex, symptoms, and a history of other diseases were not associated with efflorescence or age (p<0.05). Nonetheless, there was a connection between hypertension and dermatome location (p=0.008 <0.05). Conclusion: Herpes zoster was more common among females aged 51 to 60 years. Symptoms included discomfort and a burning sensation encircling the lesion in the left thoracal dermatomal region. The majority of patients had a prior varicella infection. Hypertension and dermatome location were correlated.
Comparative Efficacy of Alcohol-Based Chloroxylenol, Triclosan, and Gentamicin in Inhibiting Staphylococcus aureus Biofilm Formation Muhammad Jundi Aziz Ashari; Agung Dwi Wahyu Widodo; Brian Eka Rachman
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 17 No. 1 (2026): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/juxta.V17I12026.55-61

Abstract

Highlights: The combination of alcohol with triclosan and alcohol with chloroxylenol was effective in inhibiting the growth of S. aureus biofilms. Lower concentrations of gentamicin resulted in optical density (OD) values above the cut-off, suggesting that these doses were insufficient for biofilm inhibition and might potentially contribute to the persistence or stimulation of S. aureus biofilm growth.   Abstract Introduction: This study investigated the comparative efficacy of alcohol-based chloroxylenol, alcohol-based triclosan, and gentamicin in inhibiting Staphylococcus aureus biofilm formation. Biofilms formed by S. aureus present significant clinical challenges due to their antibiotic resistance and persistence in nosocomial infections. Methods: This study used the crystal violet assay with an enzyme-linked immunosorbent assay (ELISA) reader to evaluate S. aureus cultures treated with various antimicrobials. The treatments included chloroxylenol (10, 100, 1,000 ppm), triclosan (0.3, 3, 30 µg/ml), and gentamicin (5, 10, 15 mg/ml). The experiment consisted of three groups based on treatment type (n=72), each with three dosage levels (n=8). It was analyzed using the International Business Machines Corporation (IBM) Statistical Package for the Social Sciences (SPSS) version 27.0. A probability p<0.05 was considered significant. Results: The first group, chloroxylenol with alcohol, demonstrated significant inhibitory effects (n=24, p=0.007). The second group, triclosan with alcohol, exhibited the strongest antibiofilm activity (n=24, p=0.001). In contrast, the third group, gentamicin, showed no significant inhibitory effect (n=24, p=0.21). Conclusion: Chloroxylenol and triclosan exhibited significant inhibition (p=0.007 and p=0.001), whereas gentamicin did not (p=0.21). It also suggested that suboptimal gentamicin doses may contribute to biofilm persistence and adaptive responses in S. aureus. These findings underscore the potential of alcohol-based chloroxylenol and triclosan as effective agents for biofilm inhibition and highlight the need for reconsidering the role of gentamicin in treating biofilm-associated infections. Further research is warranted to explore optimal dosing strategies and the mechanisms underlying biofilm resistance.
Pattern of Laryngomalacia Cases at the Ear, Nose, and Throat Outpatient Clinic of Dr. Soetomo General Academic Hospital, Surabaya, Indonesia, 2021-2022 Stavina Dwiputri Rizky Rusuldi; Rizka Fathoni Perdana; Lynda Rossyanti; Rosydiah Rahmawati
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 17 No. 1 (2026): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/juxta.V17I12026.62-67

Abstract

Highlights: The majority of laryngomalacia patients were between 3 and 12 months. Pneumonia was the most common clinical symptom, alongside dysphagia.   Abstract Introduction: Laryngomalacia is the most frequent cause of stridor in infants and neonates. This study aimed to analyze the characteristics of patients with laryngomalacia at the Ear, Nose, and Throat (ENT) Outpatient Clinic, Dr. Soetomo General Academic Hospital, Surabaya, Indonesia, during 2021-2022. Methods: This was a descriptive retrospective study conducted at the ENT Outpatient Clinic, Dr. Soetomo General Academic Hospital, Surabaya, Indonesia, from 2021 to 2022. The research variables included age, gender, clinical symptoms, and comorbidities. Results: Most patients were in the 3-12-month age group (38 patients, 48.1%). They were followed by the age group of <3 months (27 patients, 34.18%). Forty-six (58.22%) patients were males, while there were 33 (41.78%) female patients. The most common clinical symptom in patients was pneumonia (63 patients, 36.41%), followed by dysphagia (53 patients, 30.63%). Meanwhile, the most common comorbidities in patients were craniofacial abnormalities (34 patients, 30.35%), followed by heart defects (30 patients, 26.78%). The results showed that laryngomalacia patients were dominated by babies aged 2 months, with an average age of 8 months. Conclusion: Laryngomalacia often shows with pneumonia and dysphagia. There are several comorbidities that could worsen the laryngomalacia, such as craniofacial abnormalities, heart defects, and congenital syndromes. Laryngomalacia can manifest at several days or months. Any gender is at risk of being affected by laryngomalacia.
Clinical Patterns of Pharmacotherapy Administration in Acute Heart Failure at a Tertiary Hospital in Indonesia Nadhifa Ainur Rohmah; Andrianto Andrianto; Sundari Indah Wiyasihati; Anudya Kartika Ratri
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 17 No. 1 (2026): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/juxta.V17I12026.68-73

Abstract

Highlights: Diuretics were the most commonly administered therapy for AHF patients. Pharmacotherapy administration adhered to the existing European Society of Cardiology (ESC) and the Indonesian Heart Association (PERKI) guidelines.   Abstract Introduction: Acute heart failure (AHF) has long been the leading cause of hospitalizations among the elderly. In Indonesia, AHF poses a significant challenge due to its high rates of hospitalization and mortality, with the number of cases continuing to rise annually. This study aimed to characterize the clinical pharmacotherapy patterns of AHF patients during hospitalization at Dr. Soetomo General Academic Hospital, Surabaya, Indonesia, providing valuable insights into therapeutic approaches in this tertiary care setting. Methods: This retrospective descriptive study utilized secondary data from medical records of AHF patients admitted to Dr. Soetomo General Academic Hospital, Surabaya, Indonesia, between January and December 2023. This study included 52 patients aged 18 years and older with complete medical records. All statistical procedures were performed using the International Business Machines Corporation (IBM) Statistical Package for the Social Sciences (SPSS) version 25.0 to support systematic and reproducible evaluation of the dataset. Results: This study categorized AHF treatment based on clinical manifestations, etiology, and ejection fraction. Diuretics were the most commonly used medication across all categories. Patients with acute decompensated heart failure (ADHF) and acute pulmonary edema primarily received diuretics and vasodilators, while inotropes were administered for isolated left ventricular failure. Patients with cardiogenic shock were treated with vasopressors and inotropes. Treatment patterns highlighted the tailored use of additional therapies, including vasodilators and vasopressors, according to specific clinical presentations and ejection fraction profiles. Conclusion: All medications administered to AHF patients at Dr. Soetomo General Academic Hospital, Surabaya, Indonesia, from January to December 2023 adhered to existing guidelines.
Profile of Glioma Patients at Dr. Soetomo General Academic Hospital, Surabaya, Indonesia, 2018-2022 Rizki Ahmad Fauzan; Djohan Ardiansyah; Dyah Fauziah; Yudha Haryono
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 17 No. 1 (2026): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/juxta.V17I12026.74-80

Abstract

Highlights: This study provides updated insights into glioma profiles in Indonesia, focusing on a large patient cohort from a major referral hospital. Most gliomas were large tumors located in the cerebrum, with midline shift and heterogeneous contrast enhancement being the primary radiological features observed. Glioblastoma was the predominant type, yet no significant correlation was found between radiological features and histopathological grading, highlighting a potential gap in predictive diagnostics.   Abstract Introduction: Glioma is a common brain tumor that significantly impacts patients’ quality of life by affecting motor, sensory, cognitive, and emotional functions. This study aimed to provide a holistic and comprehensive analysis of glioma characteristics by examining clinical, radiological, and histopathological data from patients treated at Dr. Soetomo General Academic Hospital, Surabaya, Indonesia, over five years from 2018 to 2022. Methods: This retrospective cross-sectional study analyzed records of 204 glioma patients from Dr. Soetomo General Academic Hospital, Surabaya, Indonesia (2018-2022). Data included demographics, clinical symptoms, tumor size and location, radiological features, and histopathological grading. Statistical analysis used Fisher’s exact test (p<0.05), and data were processed using the International Business Machines Corporation (IBM) Statistical Package for the Social Sciences (SPSS) version 23.0. Results: The most affected age group was 30-39 years old (19.1%), and it was predominantly male (59.8%). Headache was the most common presenting symptom (33.8%). Tumors were predominantly located in the cerebrum (75.9%), and most lesions measured >4 cm (76.9%). Midline shift was observed in 69.1% of cases. Contrast enhancement was described as heterogeneous in 35.8% and homogeneous in 1.5%, while 62.7% of cases lacked enhancement data. Histopathologically, the World Health Organization (WHO) grade 4 gliomas (glioblastoma) were the most frequent (39.22%). No significant association was found between radiological features (midline shift or contrast enhancement) and histopathological grading (p>0.05). Conclusion: Gliomas were predominantly found in male patients and were most common among individuals in their younger adult years. The primary clinical symptom was headache, with tumors frequently located in the cerebrum and typically presenting as large masses. Histopathologically, glioblastoma represented the most frequent and aggressive type identified.
Lack of Significant Association between Stromal Tumor-Infiltrating Lymphocytes and 2014 FIGO Stage in Epithelial Ovarian Cancer: A Cross-Sectional Study Amanda Putri; Aswiyanti Asri; Puja Agung Antonius
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 17 No. 1 (2026): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/juxta.V17I12026.81-86

Abstract

Highlights: Understanding the relationship between TIL infiltration and tumor stage could refine prognostic models and guide targeted therapies. Tumor-infiltrating lymphocytes density is considered an essential immune marker in ovarian cancer, but this study did not demonstrate a significant association with FIGO staging.   Abstract Introduction: Ovarian cancer is the fifth most common cancer among females. Prognostic factors such as stage and tumor-infiltrating lymphocytes (TILs) may influence outcomes. This study aimed to analyze the relationship between stromal TIL density and 2014 International Federation of Gynecology and Obstetrics (FIGO) staging in epithelial ovarian cancer. Methods: This cross-sectional analytical study included 44 cases (n=44) of epithelial ovarian cancer diagnosed at the Laboratory of Anatomical Pathology, Dr. M. Djamil General Hospital, Padang, Indonesia, in 2021-2022, selected using consecutive sampling. Stromal TIL density was evaluated on hematoxylin and eosin (HE) slides according to the International TILs Working Group guidelines and categorized as low (≤10%) or high (>10%). 2014 FIGO staging was obtained from medical records. Statistical analysis was performed using the International Business Machines Corporation (IBM) Statistical Package for the Social Sciences (SPSS) version 26.0, with Chi-square or Fisher’s exact test, and p<0.05 was considered significant. Results: Early-stage disease (stage I-II) comprised 25 cases (56.8%), of which 12 cases (48%) had low TIL density, and 13 cases (52%) had high TIL density. Advanced-stage disease (stage III-IV) comprised 19 cases (43.2%), of which 13 (68.4%) had low TIL density and 6 (31.6%) had high TIL density. Chi-square analysis showed no significant association between TIL density and FIGO stage (p=0.295). Conclusion: No significant relationship was found between stromal TIL density and 2014 FIGO staging in epithelial ovarian cancer. Further research with larger cohorts and detailed TIL subtypes may clarify their prognostic relevance.
Smoking as a Risk Factor for Arrhythmia in Cengkareng General Hospital, Jakarta, Indonesia, during 2020-2024 Princyelova Estevan Sutantyo; Andria Priyana
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 17 No. 1 (2026): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/juxta.V17I12026.87-92

Abstract

Highlights: No significant association was found between smoking habits and arrhythmia, despite a slightly elevated prevalence ratio. Ventricular extrasystole constituted the predominant subtype of arrhythmia observed in the study population.   Abstract Introduction: Arrhythmia is a cardiac rhythm disorder associated with stroke, heart failure, and sudden death. Smoking is an established cardiovascular risk factor, yet its relationship with arrhythmia remains insufficiently explored in Indonesia. This study aimed to examine the association between smoking habits and arrhythmia among patients at Cengkareng General Hospital, Jakarta, Indonesia. Methods: A cross-sectional study was conducted at Cengkareng General Hospital, Jakarta, Indonesia, including 140 patients aged ≥18 years old diagnosed with arrhythmia. Data were analyzed using the International Business Machines Corporation (IBM) Statistical Package for the Social Sciences (SPSS) version 25.0. Results: Of all participants, 59.3% were males and 20.7% were smokers. Arrhythmia was detected in 95.7% of cases, with ventricular extrasystole (VES) being most frequent (65%). Statistical analysis demonstrated no significant association between smoking and arrhythmia, although smokers exhibited a marginally higher risk (probability/Pr=1.011). Hypertension, diabetes mellitus (DM), renal dysfunction, and medication use were also identified as contributing factors. Conclusion: Although smoking was not significantly associated with arrhythmia, it showed a tendency to increase risk. Ventricular extrasystole was the predominant arrhythmia observed in this cohort.

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