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Andalas obstetrics and gynecology journal
Published by Universitas Andalas
ISSN : 25798324     EISSN : 25798413     DOI : https://doi.org/10.25077/aogj
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Immunology & microbiology Nursing Public Health
Andalas Obstetrics And Gynecology Journal (AOJ) (e-ISSN: 2579-8324) is a peer-reviewed, open-access national journal published by Universitas Andalas and is dedicated to publish and disseminate research articles, literature reviews, and case reports, in the field of obstetrics, gynecology, and other related disciplines.
Arjuna Subject : Kedokteran - Obstetrics and Gynaecology
Articles 17 Documents
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Search results for , issue "Vol. 6 No. 1 (2022)" : 17 Documents clear
Adult Women with Congenital Adrenal Hyperplasia (CAH) Muhammad Rudi Setiawan; Ichsan Arif; Bobby Indra Utama
Andalas Obstetrics And Gynecology Journal Vol. 6 No. 1 (2022)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.6.1.110-115.2022

Abstract

Introduction : Congenital Adrenal Hyperplasia (CAH) is the most common cause of ambiguous genitalia. It is a genetic disorder that occurs due to failure or disruption of the formation of enzymes which play a role in the production of cortisol and aldosterone and can cause fusion of the labia, clitoromegaly, and a fusion of the vagina and distal urethra.Case Reports:A 32-year-old patient, unmarried, came to the urogynecology department complaining of thickening of the upper genitalia that resembles male genitalia. This problem has been known to the patient since she was 16 years old and was brought to the doctor at the age of 21 and diagnosed with congenital adrenal hyperplasia. The patient has had menstruation since she was 14 years old, but it is irregular. Since 8 years ago, the patient has been regularly taking hydrocortisone from an internal medicine specialist but has never been to the obstetrics and gynecology department for 8 years, now the patient comes to the urogynecology department because she wants to get married. When the patient was in school, she grew up like a normal woman and have good academic abilities. In the family history, there was no family history of congenital abnormalities. From physical examination, her height is 150 cm. She shows the habitus of external body like a woman. On genital examination found no formation of labia, clitoromegaly. Karyotype 46, XX. Ultrasonography found uterus and ovaries within normal limits.Conclusion:Counseling, both surgical and non-surgical treatment with a multidisciplinary approach, will give good results in patients with CAH. Rapid diagnosis and treatment will provide good management for patients with CAH. Surgery in the form of reducing the size of the clitoris (while maintaining the function of sensation), as well as expanding the vaginal opening can help in these patients to improve the patient's quality of life.Keywords: Congenital Adrenal Hyperplasia; clitoromegaly; unmarried
Placenta Percreta With Bladder Infiltration : A Case Report Poldo Reinaldo; Bayu Permana; Syahredi Syahredi
Andalas Obstetrics And Gynecology Journal Vol. 6 No. 1 (2022)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.6.1.104-109.2022

Abstract

Objective : To report a case of placenta percreta with bladder infiltration.Method : Case reports.Case :a 24-year-old female G2P1A0H1 gravid 26-27 weeks, placenta percreta with gross hematuria. The second pregnant patient was less months pregnant with the results of a fetal ultrasound examination with a placenta covering the uterine internum (OUI) and suspected of penetrating the uterine wall (percreta), and a cesarean hysterectomy was performed.Discussion : The cause of placenta percreta is unknown, it is associated with several clinical risk factors like the previous cesarean, placenta previa, grand multiparity, and previous uterine curettage. The management of placenta percreta can be challenging because the loss occurs at two sites in labor. Refractory hematuria occurs in 25% of patients due to placenta percreta invasion of the bladder. Management involves a team of obstetricians, urologists, intensivists, and neonatologists. Treatment is preferably carried out in tertiary care where there is a definite stock of blood with adequate blood products, a fully equipped neonatal intensive care unit (NICU). Delivery may be considered at 34-35 weeks gestation if there is no maternal and fetal deterioration because the incidence of antepartum hemorrhage appears to increase sharply at 36 weeks.Conclusion : Management is recommended for placenta percreta cases, planning for premature cesarean hysterectomy with placenta left in situ. However, the diagnosis is made based on the results of the anatomic pathology obtained after hysterectomy, and is not considered a first-line treatment for women who still wish to maintain future fertility.Keywords:placenta percreta, cesarean hysterectomy
MULTI DRUG RESISTANT TUBERCULOSIS IN PREGNANCY muharam, maulana; Firina, Dewi Wahyu; Mizarti, Dessy
Andalas Obstetrics And Gynecology Journal Vol. 6 No. 1 (2022)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.6.1.1-15.2022

Abstract

Tuberculosis can develop to multi drug resistant tuberculosis, this will be a serious health problem, not only in Indonesia, also in the world. This disease complexity, length of treatment, adverse effect of drug, make it management become challenging. Pregnancy with physiological changes in it made pregnant woman susceptible to infection, include tuberculosis infection. Data about MDR TB in pregnancy were not much, because TB screening in pregnancy were not often done, also pregnancy it self almost exclude from any trial. Because of MDR TB regiment adverse effect, much of clinician suggest woman in MDR TB treatment to not get pregnant while on it. Management MDR TB on pregnancy use individual regiment, by keep secure and safety aspect of patient, also her fetus.
DIFFERENCES IN PROTEASE ACTIVATED RECEPTOR-1 AND THROMBINE LEVELS IN PREECLAMPSIA AND NORMAL PREGNANCY Khatimah, Gistin Khusnul; Serudji, Joserizal; Basyir, Vaulinne
Andalas Obstetrics And Gynecology Journal Vol. 6 No. 1 (2022)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.6.1.27-34.2022

Abstract

Introduction: Preeclampsia is a condition caused by alterations in endothelial function during pregnancy. Changes in endothelial function result in an increase in coagulation and microvascular fibrin accumulation, which results in impaired placental perfusion. Thrombin, which converts fibrin to fibrinogen, as well as platelet activity, the fibrinolytic system, and anticoagulants, are all procoagulant circumstances in preeclampsia. Thrombin contributes to the pathogenesis of preeclampsia by increasing the expression of sFlt-1 thereby providing an antiangiogenic response. Protease Activated Receptor-1 (PAR-1) is a mediator of thrombin for coagulation and inflammation in preeclampsia. Inhibition of Protease Activated Receptor-1 expression in trophoblasts can enhance placental angiogenesis and vascular remodeling. Recently, only few studies have assessed the levels of Protease Activated Receptor -7 and thrombin in preeclampsia.Objective: To determine the difference in levels of Protease Activated Receptor-1 and thrombin in preeclampsia and normal pregnancyMethods: This study is observational with a cross-sectional comparative study design. Sampling was conducted from March 2020 to March 2021. A total of 66 patients were investigated, with 33 samples of preeclampsia and 33 samples of normal pregnancy. The independent sample T-test was used for statistical analysis.Results: The mean levels of Protease Activated Receptor-1 in the preeclampsia group were higher at 28.56 ± 7.68 ng/mL while normal pregnancy was 21.67 ± 6.92 ng/mL. The results of statistical tests showed that there was a significant difference in levels of Protease Activated Receptor-1 between the preeclampsia and normal pregnancy groups (p<0.05). The mean thrombin level in the preeclampsia group was higher at 72.23 ± 7.99 ng/mL, while in normal pregnancy it was 63.70 ± 8.92 ng/mL. The difference in thrombin levels between the preeclampsia and normal pregnancy groups was statistically significant (p<0.05).Conclusion: Preeclampsia was associated with greater levels of Protease Activated Receptor-1 and thrombin than normal pregnancy. There was a significant difference in the mean levels of Protease Activated Receptor-1 and thrombin between preeclampsia and normal pregnancy.Keywords: Thrombin, Protease Activated Receptor-1(PAR-1), Preeclampsia
Semen Quality of Infertile Men and Correlation with Demographic Characterictics Iqbal, Muhammad; Karmia, Hudila Rifa; Alvarino, Alvarino
Andalas Obstetrics And Gynecology Journal Vol. 6 No. 1 (2022)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.6.1.58-64.2022

Abstract

Objective: To analyze semen quality of infertile men and its correlation with demographics characteristics.Methods: This was an analytic observational study with cross-sectional retrospective study design on 92 infertile men. The study began in May 2021 to December 2021 in the Obstetrics and Gynecology Clinics at BMC Hospital Padang.Results:The correlation between age and marital duration was positively correlated (r= 0,558), with a weak correlation and there is statistically significant relationship between age and marital duration. Age and sperm concentration was positively correlated (r=0.048), with a weak correlation. Marital duration and sperm concentration was positively correlated (r=0.052), with a weak correlation. The correlation between age and progressive motility and non-progressive motility percentage were positively correlated (r = 0.009 and 0.035),with a weak correlation. The correlation between age and progressive immotile sperm percentage were negatively correlated (r = - 0,030),with a weak correlation.Conclusion: There was a positive correlation between age and sperm concentration, and progressive and non progressive motility with a weak correlation. There was a positive correlation between age and marital duration with a strong correlation. There was negative correlation between and sperm immotility with a weak correlation.Keywords:  male infertility, semen, age, marital duration
Comparison of womwne's quality of life post abdominal and vaginal hysterectomy F, Fauzan; Utama, Bobby Indra; Firdawati, Firdawati
Andalas Obstetrics And Gynecology Journal Vol. 6 No. 1 (2022)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.6.1.35-41.2022

Abstract

Introduction:Hysterectomy is the most common major surgical procedure in gynecology. Approximately 90% of hysterectomies are performed on indications of benign gynecological disease. The number of women affected by hysterectomy is relatively low, but the impact of these complications often changes the quality of life. There are several types of hysterectomy, from partial/supravaginal, complete/total, to radical. Hysterectomy with any surgical technique can cause complications. This can be minimized by careful surgical planning and preparation before surgeryAssessing changes in quality of life after surgery is important for patient decision making and for health care evaluation, as health care becomes more standardized. Objective: This study aims to determine the difference in quality of life between women who have undergone abdominal hysterectomy surgery and women who have undergone vaginal hysterectomy surgery.Methods: This research is an analytic observational study with a cross sectional comparative study approach which was conducted on 54 women who had undergone hysterectomy at Dr. RSUP. M. Djamil, Padang. 27 of them underwent abdominal hysterectomy, and 27 others underwent vaginal hysterectomy. All patients were interviewed using the Short Form-36 (SF-36) questionnaire. The assessment is carried out with a scoring system where a score of 0 is the lowest value, and 100 is the highest value.Results: The average quality of life of the woman's post abdominal and vaginal hysterectomy was 91.71 ± 6.73 and 99.07 ± 1.66 respectively. There is a difference in the mean value of quality of life of women and post abdominal and vaginal hysterectomy (p<0.05).Conclusion: There was a significant difference between the quality of life of women after hysterectomy, where women who underwent vaginal hysterectomy had a higher quality of life than women who underwent abdominal hysterectomyKeywords: Hysterectomy, Abdominal, Vaginal, Quality of life
Factors Related to the Success of IVF Program in Morula BMC Clinic Padang Dewi, Nurmala Sari; Hendri, Dedy; Bachtiar, Hafni
Andalas Obstetrics And Gynecology Journal Vol. 6 No. 1 (2022)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.6.1.50-57.2022

Abstract

Introduction: Infertility is the failure of a couple to get pregnant 12 months after having regular sex without contraception. One in seven couples even have to be treated using Assisted Reproductive Technology (TRB). The most widely used TRB is In Vitro Fertilization (IVF). In general, the success rate is in the range of 40-50%. In Indonesia, there are 32 clinics providing IVF program with a success rate of 30-40%. The success rate of IVF is influenced by multi variables that affect directly or indirectly including age, Antral Follicle Count (AFC), Anti Mullerian Hormone (AMH), basal Follicle Stimulating Hormone (FSH), number of egg cells, egg quality, sperm quality, embryo quality, and endometrial thickness. Objectives: This study aims to determine the factors associated with the success of IVF programMethods: This study used a cross-sectional analytic study design which was conducted on 77 medical records of patients undergoing IVF program at Morula Clinic BMC Padang from January 2018-December 2020. All data were then analyzed using univariate, bivariate and multivariate analysis with appropriate statistical test; Results: The average age of the study subjects was (33.4 ± 3.93) years, the average length of infertility was (6.73 ± 3.69) years, the most used antagonist protocols (88.16%), with the most common causes of infertility being factors sperm (48.9%) and overweight BMI (36.4%). From the bivariate analysis, it was found that the factors related to the number of eggs were age (r = -0.349), AFC (r = 0.471), FSH (p 0.02), and AMH (p < 0.01) with the dominant factor being AMH. Egg quality was related to AFC (p 0.007) and FSH (p 0.002), with the dominant factor being AFC. Embryo quality correlated with egg quality (p < 0.01). Meanwhile, the success of implantation was dominantly related to the embryo quality factor (0.034); Conclusion: The most dominant factor to the success of IVF program is the quality of the embryo.Keywords: IVF, IVF success
Analysis of the stress level of resident physician education program specialist in Obstetrics and Gynecology Andalas University in 2020 Fajri, Ari Fuad; Utama, Bobby Indra; Hardisman, Hardisman
Andalas Obstetrics And Gynecology Journal Vol. 6 No. 1 (2022)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.6.1.65-71.2022

Abstract

Introduction:The Specialist Doctor Education Program (PPDS) is one of the academic education of general practitioners and is known as a resident doctor to become a specialist and is at the forefront ofhealth services. Resident doctors are expected to be flexible clinicians, educators, researchers, andadministrators by the end of their residency training. It often requires stressful hard work, and is oftenreported as a cause of burnout, anxiety, depression, anger, irritability, anxiety, sleep deprivation,fatigue, substance abuse, and psychosocial problems. One of the problems that often occurs with residents is long working hours. Based on the working hours regulation adopted in the UK since 1998, namely the European Working Time Directive (EWTD) and a policy change in 2007 and 2009 called The New Deal, the working hours of resident doctors to achieve optimal performance is 56 hours per week. In the initial survey of 10 PPDS Obgin Unand residents, network station residents still had to carry out their duties 24 hours a day for 1 month in the hospital. Except for applying for certain permits. If you add up, the average working hours in 1 week is more than 60 working hours. Objective: This study aims to determine the stress level of resident doctors in the Education Program of  Obstetric and Gynecology Specialist, Andalas University in 2020Methods: This research is a quantitative study followed by qualitative method using an explanatory design. Data was taken using the triangulation method. The data was taken from questionnaires, Focus Group Discussion (FGD), and document review from Obstetric and Gynecology residents of all semester at Andalas University.Results: The highest stress level in the Obstetric and Gynecology residents of Andalas University in 2020 was 60.3% at moderate level, there was a relationship between stress levels with graduation and semester. The highest stress domain is ARS (Academic Related Stressor) and SRS (Social Related Stressor).Conclusion: the stress level in the Obstetric and Gynecology residents of Andalas University in 2020 is at a moderate level, and the highest stress domain is ARS (Academic Related Stressor) and SRS (Social Related Stressor).Keywords: Resident Doctor; Obstetric and Gynecology; stress
The relationship delay in referral with maternal mortality Dr. M. Djamil central general hospital Padang Hasjmy, Ibnu Razi Mulya; Ferry, Ferdinal; Bachtiar, Hafni
Andalas Obstetrics And Gynecology Journal Vol. 6 No. 1 (2022)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.6.1.71-81.2022

Abstract

Introduction: Maternal mortality is maternal death during pregnancy, childbirth, and 42 days after delivery. Maternal Mortality Rate (MMR) is the number of maternal deaths per 100,000 live births. There was an increase in MMR in Indonesia on 2012 compared to 2007 which is 228 per 100,000 population. There were 17 maternal deaths at Dr. M. Djamil Hospital throughout 2019. Delay in referral can cause death for both mother and infantObjectives: This study aims to determine the relationship between delay in referral and maternal mortality in obstetric emergencies that came to the emergency unit at Dr. M. Djamil Hospital, Padang.Methods: This study used a cross-sectional comparative study design conducted on 90 pregnant women who visited Dr. M. Djamil Padang Hospital from January - February 2021. All data were then analyzed using univariate and bivariate analysis with appropriate statistical tests.Results: The mean age of the study subjects was 25.34 ± 5.99 years old with 12.21% of sample were nullipara, 21.27% primipara, 61.83% multipara, and 4.58% grande multipara. From the questionnaire, 54.3% were late to refer. From the medical records, it was found that in the group who died, 94.5% experienced a delay in referral and bivariate analysis showed a relationship between late referral and maternal mortality (p = 0.000).Conclusion: There is a significant relationship between late referral and maternal mortality at Dr. M. Djamil Central General Hospital PadangKeywords: Maternal Mortality Rate; late referrals; pregnant women
Amnioinfusions to Treat Early Onset Anhydramnios Caused by Bilateral Renal Agenesis : Potter’s Syndrome Yusrawati, Yusrawati; Yusra, Rizka Fadhillah
Andalas Obstetrics And Gynecology Journal Vol. 6 No. 1 (2022)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.6.1.89-97.2022

Abstract

Introduction: Anhydramnios is a very small amount of amniotic fluid where the MVP measurement is 2cm by ultrasound. The most common cause of anhydramnios that persists into the second trimester of pregnancy is bilateral renal agenesis. Bilateral renal agenesis is closely related to Potter's Syndrome. Potter's syndrome is a picture of reduced amniotic fluid regardless of the cause. The most common cause of newborn death in cases of anhydramnios is pulmonary hypoplasia. Amnioinfusion is an action of adding fluid into the amniotic cavity which is expected to reduce uterine pressure due to anhydramnios and maintain alveolar distension to increase fetal lung growth.Objective: The aim of this case report is to share amnioinfusion on anhydramnios.Case Report: A 26-year-old woman G3P1A1H1 gravid 27-28 weeks was referred to the fetomaternal polyclinic of RSUP M. Djamil Padang with suspicion of anhydramnios caused by bilateral renal agenesis. Physical and obstetric examinations were found to be within normal limits. On ultrasound examination, there was no amniotic fluid, so MVP was difficult to assess, no fetal kidney and bladder were seen, so it is suspected that this is a bilateral renal agenesis disorder and leads to Potter's Syndrome. The patient was subjected to amnioinfusion to prevent contractures and pulmonary hypoplasia in the fetus. From the first amnioinfusion, the MVP increased to 2.99 cm. Monitoring and amnioinfusion are carried out periodically until the fetus is viable to be bornConclusion: Amnioinfusion in bilateral renal agenesis is useful for assisting diagnosis and as a preventive therapy for pulmonary contractures and hypoplasia in the fetus as well as increasing life expectancy when the fetus is born.Keywords: Bilateral Renal Agenesis, Anhydramnios, Amnioinfusion, Potter's Syndrome

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