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Andalas obstetrics and gynecology journal
Published by Universitas Andalas
ISSN : 25798324     EISSN : 25798413     DOI : https://doi.org/10.25077/aogj
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Immunology & microbiology Nursing Public Health
Andalas Obstetrics And Gynecology Journal (AOJ) (e-ISSN: 2579-8324) is a peer-reviewed, open-access national journal published by Universitas Andalas and is dedicated to publish and disseminate research articles, literature reviews, and case reports, in the field of obstetrics, gynecology, and other related disciplines.
Arjuna Subject : Kedokteran - Obstetrics and Gynaecology
Articles 469 Documents
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Factors Related to the Success of IVF Program in Morula BMC Clinic Padang Nurmala Sari Dewi; Dedy Hendri; Hafni Bachtiar
Andalas Obstetrics And Gynecology Journal Vol 6, No 1 (2022)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.6.1.50-57.2022

Abstract

Introduction: Infertility is the failure of a couple to get pregnant 12 months after having regular sex without contraception. One in seven couples even have to be treated using Assisted Reproductive Technology (TRB). The most widely used TRB is In Vitro Fertilization (IVF). In general, the success rate is in the range of 40-50%. In Indonesia, there are 32 clinics providing IVF program with a success rate of 30-40%. The success rate of IVF is influenced by multi variables that affect directly or indirectly including age, Antral Follicle Count (AFC), Anti Mullerian Hormone (AMH), basal Follicle Stimulating Hormone (FSH), number of egg cells, egg quality, sperm quality, embryo quality, and endometrial thickness. Objectives: This study aims to determine the factors associated with the success of IVF programMethods: This study used a cross-sectional analytic study design which was conducted on 77 medical records of patients undergoing IVF program at Morula Clinic BMC Padang from January 2018-December 2020. All data were then analyzed using univariate, bivariate and multivariate analysis with appropriate statistical test; Results: The average age of the study subjects was (33.4 ± 3.93) years, the average length of infertility was (6.73 ± 3.69) years, the most used antagonist protocols (88.16%), with the most common causes of infertility being factors sperm (48.9%) and overweight BMI (36.4%). From the bivariate analysis, it was found that the factors related to the number of eggs were age (r = -0.349), AFC (r = 0.471), FSH (p 0.02), and AMH (p < 0.01) with the dominant factor being AMH. Egg quality was related to AFC (p 0.007) and FSH (p 0.002), with the dominant factor being AFC. Embryo quality correlated with egg quality (p < 0.01). Meanwhile, the success of implantation was dominantly related to the embryo quality factor (0.034); Conclusion: The most dominant factor to the success of IVF program is the quality of the embryo.Keywords: IVF, IVF success
Placenta Percreta With Bladder Infiltration : A Case Report Poldo Reinaldo; Bayu Permana; Syahredi Syahredi
Andalas Obstetrics And Gynecology Journal Vol. 6 No. 1 (2022)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.6.1.104-109.2022

Abstract

Objective : To report a case of placenta percreta with bladder infiltration.Method : Case reports.Case :a 24-year-old female G2P1A0H1 gravid 26-27 weeks, placenta percreta with gross hematuria. The second pregnant patient was less months pregnant with the results of a fetal ultrasound examination with a placenta covering the uterine internum (OUI) and suspected of penetrating the uterine wall (percreta), and a cesarean hysterectomy was performed.Discussion : The cause of placenta percreta is unknown, it is associated with several clinical risk factors like the previous cesarean, placenta previa, grand multiparity, and previous uterine curettage. The management of placenta percreta can be challenging because the loss occurs at two sites in labor. Refractory hematuria occurs in 25% of patients due to placenta percreta invasion of the bladder. Management involves a team of obstetricians, urologists, intensivists, and neonatologists. Treatment is preferably carried out in tertiary care where there is a definite stock of blood with adequate blood products, a fully equipped neonatal intensive care unit (NICU). Delivery may be considered at 34-35 weeks gestation if there is no maternal and fetal deterioration because the incidence of antepartum hemorrhage appears to increase sharply at 36 weeks.Conclusion : Management is recommended for placenta percreta cases, planning for premature cesarean hysterectomy with placenta left in situ. However, the diagnosis is made based on the results of the anatomic pathology obtained after hysterectomy, and is not considered a first-line treatment for women who still wish to maintain future fertility.Keywords:placenta percreta, cesarean hysterectomy
DIFFERENCES IN PROTEASE ACTIVATED RECEPTOR-1 AND THROMBINE LEVELS IN PREECLAMPSIA AND NORMAL PREGNANCY Gistin Khusnul Khatimah; Joserizal Serudji; Vaulinne Basyir
Andalas Obstetrics And Gynecology Journal Vol 6, No 1 (2022)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.6.1.27-34.2022

Abstract

Introduction: Preeclampsia is a condition caused by alterations in endothelial function during pregnancy. Changes in endothelial function result in an increase in coagulation and microvascular fibrin accumulation, which results in impaired placental perfusion. Thrombin, which converts fibrin to fibrinogen, as well as platelet activity, the fibrinolytic system, and anticoagulants, are all procoagulant circumstances in preeclampsia. Thrombin contributes to the pathogenesis of preeclampsia by increasing the expression of sFlt-1 thereby providing an antiangiogenic response. Protease Activated Receptor-1 (PAR-1) is a mediator of thrombin for coagulation and inflammation in preeclampsia. Inhibition of Protease Activated Receptor-1 expression in trophoblasts can enhance placental angiogenesis and vascular remodeling. Recently, only few studies have assessed the levels of Protease Activated Receptor -7 and thrombin in preeclampsia.Objective: To determine the difference in levels of Protease Activated Receptor-1 and thrombin in preeclampsia and normal pregnancyMethods: This study is observational with a cross-sectional comparative study design. Sampling was conducted from March 2020 to March 2021. A total of 66 patients were investigated, with 33 samples of preeclampsia and 33 samples of normal pregnancy. The independent sample T-test was used for statistical analysis.Results: The mean levels of Protease Activated Receptor-1 in the preeclampsia group were higher at 28.56 ± 7.68 ng/mL while normal pregnancy was 21.67 ± 6.92 ng/mL. The results of statistical tests showed that there was a significant difference in levels of Protease Activated Receptor-1 between the preeclampsia and normal pregnancy groups (p<0.05). The mean thrombin level in the preeclampsia group was higher at 72.23 ± 7.99 ng/mL, while in normal pregnancy it was 63.70 ± 8.92 ng/mL. The difference in thrombin levels between the preeclampsia and normal pregnancy groups was statistically significant (p<0.05).Conclusion: Preeclampsia was associated with greater levels of Protease Activated Receptor-1 and thrombin than normal pregnancy. There was a significant difference in the mean levels of Protease Activated Receptor-1 and thrombin between preeclampsia and normal pregnancy.Keywords: Thrombin, Protease Activated Receptor-1(PAR-1), Preeclampsia
Analysis of the stress level of resident physician education program specialist in Obstetrics and Gynecology Andalas University in 2020 Ari Fuad Fajri; Bobby Indra Utama; Hardisman Hardisman
Andalas Obstetrics And Gynecology Journal Vol 6, No 1 (2022)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.6.1.65-71.2022

Abstract

Introduction:The Specialist Doctor Education Program (PPDS) is one of the academic education of general practitioners and is known as a resident doctor to become a specialist and is at the forefront ofhealth services. Resident doctors are expected to be flexible clinicians, educators, researchers, andadministrators by the end of their residency training. It often requires stressful hard work, and is oftenreported as a cause of burnout, anxiety, depression, anger, irritability, anxiety, sleep deprivation,fatigue, substance abuse, and psychosocial problems. One of the problems that often occurs with residents is long working hours. Based on the working hours regulation adopted in the UK since 1998, namely the European Working Time Directive (EWTD) and a policy change in 2007 and 2009 called The New Deal, the working hours of resident doctors to achieve optimal performance is 56 hours per week. In the initial survey of 10 PPDS Obgin Unand residents, network station residents still had to carry out their duties 24 hours a day for 1 month in the hospital. Except for applying for certain permits. If you add up, the average working hours in 1 week is more than 60 working hours. Objective: This study aims to determine the stress level of resident doctors in the Education Program of  Obstetric and Gynecology Specialist, Andalas University in 2020Methods: This research is a quantitative study followed by qualitative method using an explanatory design. Data was taken using the triangulation method. The data was taken from questionnaires, Focus Group Discussion (FGD), and document review from Obstetric and Gynecology residents of all semester at Andalas University.Results: The highest stress level in the Obstetric and Gynecology residents of Andalas University in 2020 was 60.3% at moderate level, there was a relationship between stress levels with graduation and semester. The highest stress domain is ARS (Academic Related Stressor) and SRS (Social Related Stressor).Conclusion: the stress level in the Obstetric and Gynecology residents of Andalas University in 2020 is at a moderate level, and the highest stress domain is ARS (Academic Related Stressor) and SRS (Social Related Stressor).Keywords: Resident Doctor; Obstetric and Gynecology; stress
Ovarian goiter with papillary thyroid carcinoma: A very rare case Puja Agung Antonius; Dr. dr. Syamel Muhammad, SpOG(K)-Onkogin; Muhammad Zaldy Rasyid Putra; Santy Saberko
Andalas Obstetrics And Gynecology Journal Vol. 6 No. 2 (2022)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.6.2.179-183.2022

Abstract

Struma ovarii is a rare condition, in which thyroid tissue is the predominant element in an ovarian carcinoma. Thyroid tissue may demonstrate the same spectrum of pathological features as in the normal thyroid including benign and malignant changes. The malignant type is very rare, only 5% from all incidents of goiter ovarii. We present a case of papillary thyroid carcinoma arising in a struma ovarii of the right ovary in a 43-year-old female
Congenital Heart Defects: Risk Stratification for Pregnancy Joserizal Serudji
Andalas Obstetrics And Gynecology Journal Vol. 6 No. 2 (2022)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.6.2.116-121.2022

Abstract

Major advances in medicinal and operative therapy on congenital heart defects (CHD) patients have led the majority of affected women survive to childbearing age. The risk of cardiovascular complications during pregnancy and peripartum depends on the type of the underlying defect, the extent and severity of residual haemodynamic lesions and comorbidities. Thuugh pregnancy is well tolerated in patients with CHD, but for some women with particularly high-risk lesions and poor functional class, pregnancy poses significant risk for cardiovascular complications, including premature death. As a result, preconception risk stratification and counseling are mandatory and should be done in all women of childbearing age with CHD. This will enable informed decision making for pregnancy savers.
A Case Report: Vesico Vaginal Fistula Rezi Amalia; Yulia Margaretta Sari`
Andalas Obstetrics And Gynecology Journal Vol. 6 No. 2 (2022)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.6.2.209-213.2022

Abstract

Background: Vesica vaginal fistula is a part of urogenital fistula wich condition that present fistula between bladder and vagina and make urine mold through vagina. Case Report: Nullipara woman, 48 years old, admitted with complaining mold of urine from vagina since ten months ago after seven days having surgery procedure. Complaint appeared seven days after hysterctomi procedure as indication of uterine myoma. The vital signs are normal. On Per Speculum examination, clearly see there are fluids on the posterior fornix. Methylene blue test show result one fistula is at the top anterior of vagina, 6 cm proximal from hymenal ring about 1-1.5 cm. The patient underwent fistulorraphy with a vaginal approach using the futh mayo technique Discussion: Vesica vaginal fistula usually occur in the development country. Predisposition factors of it caused by hysterectomy procedure, besides trauma during labor and complications of pelvic surgery may also too. Physical and additional specific examination conventionally or minimally invasive like cystoscopy, cystography with contrast can obtain diagnosis, determine the location, size and number of fistula. Surgery is the mainstay therapy for urogenital fistula through trans vaginal or trans abdomen. Approaching depends on knowledge, experience and collaboration with other experts if needed. Surgery is the mainstay therapy for urogenital fistula through trans vaginal or trans abdomen. Approaching depends on knowledge, experience and collaboration with other experts if needed. Surgery is the mainstay therapy for urogenital fistula through trans vaginal or trans abdomen. Approaching depends on knowledge, experience and collaboration with other experts if needed.
Pregnancy confirmed COVID-19 in hospital Dr. M. Djamil Padang periode 2020-2021 Aladin Aladin; Linosefa Linosefa; Muhammad Rafky Alfi Putra
Andalas Obstetrics And Gynecology Journal Vol. 6 No. 2 (2022)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.6.2.152-158.2022

Abstract

Introduction: Coronavirus disease 2019 (COVID-19) caused a highly acute respiratory infection and high mortality. Symptoms of COVID-19 would be more severe if it affects people at high risk, one of which is pregnant women. This study aims to determine the characteristics of pregnant women with confirmed COVID-19 at RUSP Dr. M. Djamil Padang Objective: to find out the profile of the maternal charactheristic confirmed COVID-19 in hospital Dr. M. Djamil Padang Periode 2020-2021. Methods: This type of research is descriptive with a total sampling technique using secondary data, namely patient medical records. The sample of this study were all pregnant women who were confirmed to have COVID-19 at RSUP Dr. M. Djamil Padang for the 2020-2021 period with a total sample of 186 patient medical records. Univariate data analysis is presented in the form of frequency distribution and data processing using the Computerized SPSS version of the IBM version 26.0. Results: The highest age group was 20-35 years old (78%), the most addresses were Padang City (43,5). %), the most gravida status was multigravida (71,5%), the most parity status was multipara (38,2%), the most gestational age was third trimester (81,7%), the most clinical symptoms are asymptomatic (44,1 %), and the most comorbid status was without comorbid (82,3%). Conclusion: The most pregnant women have confirmed COVID-19 at RSUP Dr. M. Djamil Padang in 2020-2021 with characteristics of age 20-35 years, address in Padang City, status of multigravida and multiparous pregnancy, third trimester gestational age, asymptomatic and no comorbidities.
Pulmonary TB in Pregnancy Efriza Naldi; Nurmala Sari Dewi
Andalas Obstetrics And Gynecology Journal Vol. 6 No. 2 (2022)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.6.2.184-190.2022

Abstract

Objective : To report a case of pulmonary TB in pregnancyMethod : A case reportCase : Presented a case of cpulmonar TB in pregnancy on 33-year-old patient. This is fifth pregnancy with twice history of abortion, malnutrition and pulmonary TB (in treatment). The result of chest x-rays was pulmonary TB. The patient was on treatment for anti-tuberculosis drugs for second month. Patient had BMI was 16,88 kg/m2 which is underweight category. There were bronchovesicular and ronchi from both side of lung from auscultation examination. From laboratory findings there was decrease of albumin serum levels to 2,1 gr%. From ultrasound got impression 16-17 weeks of pregnancy. Patient got anti tuberculosis drugs treatment category I incentive phase (2HRZE). During hospitalization treatment, patient was given some nutrition consultation and high calories and high protein diet and also extra 3 egg whites per day. Total calories are 2250 kcal. Patient also got 1 infuse bottle of albumin and albumin supplementation.Discussion : . The incidence of TB in pregnancy was 1/10,000 pregnancies. .. Provision of an appropriate and adequate chemotherapy regimen will improve the quality of life of the mother, reduce the side effects of anti-tuberculosis drugs (OAT) on the fetus and prevent infection in newborns. Patient got anti tuberculosis drugs treatment category I incentive phase (2HRZE) which is no difference theraphy with no-pregnant patient. Patient was not given pyridoxine as adjuvant drugs along with the anti- tuberculosis drugs. Pyridoxine supplementation must be given with the dose  of 50 mg/day and is suggested for every pregnant woman who consumes isoniazid because the deficiency often happens in pregnancy than general population.Conclusion The diagnosis of this patient was correct based on anamnesis, physical examination, and supporting test . Active TB treatment in pregnancy doesn’t have any difference with non-pregnant. The management of this patient is not correct because the patient didn’t get pyridoxine supplementation, didn’t undergo sputum test in second month, and wasn’t done culture M. Tuberculosis as a gold standard. 
Bacteriological Profile and Antibiotic Sensitivity Pattern of Surgical Site Infection Following Gynecologic Oncology Surgery at Hasan Sadikin General Hospital Kemala Isnainiasih Mantilidewi; Ali Budi Harsono; Jessica Kireina; Jaeni Pringgowibowo; Windy Natasya Al Baihaqi
Andalas Obstetrics And Gynecology Journal Vol. 6 No. 2 (2022)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.6.2.122-129.2022

Abstract

Introduction: Surgical site infection (SSI) is the most common complication of gynecologic oncology surgeries. Understanding the characteristics, bacteriological profile, and antibiotic sensitivity pattern of SSI patients can help guide patient’s management and reduce morbidity, mortality, and economic burden caused by SSI. The aim of this study is to describe the characteristics, bacteriological profile, and antibiotic sensitivity pattern of SSI patients following gynecologic oncology surgery at Hasan Sadikin General Hospital Bandung in 2021. Methods: This is a descriptive study that analyzed medical records of patients undergoing gynecologic oncology surgery at Hasan Sadikin Hospital Bandung from January to December 2021. Results: Out of 157 gynecologic oncology surgeries in 2021 that met the criteria, there were 11 incidences of SSI (7%). All SSI patients received postoperative antibiotics, with the most common type of antibiotic given being a combination of ceftriaxone and metronidazole. Ten out of the 11 specimens from SSI patients showed bacterial growth and a total of 17 bacterial isolates were found. Most specimens showed polymicrobial infection with the most common isolate being Escherichia coli Extended-Spectrum Beta-Lactamase (ESBL). Gram-positive bacteria in this study were most sensitive to Vancomycin, Tigecycline, and Gentamicin. Meanwhile, gram-negative bacteria were most sensitive to Ertapenem and Meropenem. Conclusion: Incidence of SSI following gynecologic oncology surgery at Hasan Sadikin General Hospital in 2021 is 7%. The most frequently found isolate was Escherichia coli ESBL. Gram-positive bacteria were most sensitive Vancomycin, Tigecycline, and Gentamicin; while gram-negative bacteria were most sensitive to Ertapenem and Meropenem.

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