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All Journal Jurnal Kesehatan Andalas Molecular and Cellular Biomedical Sciences (MCBS) Syntax Literate: Jurnal Ilmiah Indonesia Indonesian Journal of Obstetrics & Gynecology Science Journal of Midwifery JIK- JURNAL ILMU KESEHATAN Health and Medical Journal Andalas obstetrics and gynecology journal Jurnal Health Sains Jurnal Ilmu Kesehatan Indonesia (JIKSI) Jurnal Riset Ilmiah
Antonius, Puja Agung
Andalas University
Humanities Biochemistry, Genetics & Molecular Biology Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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HUBUNGAN INFEKSI Chlamydia trachomatis DENGAN KEJADIAN ABORTUS SPONTAN DI RSUD DR. RASIDIN DAN RSIA SITI HAWA PADANG Wenny Nursa Octarina; Andani Eka Putra; Puja Agung Antonius
Jurnal Kesehatan Andalas Vol 7 (2018): Supplement 3
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v7i0.863

Abstract

Abortus merupakan salah satu penyebab dari morbiditas dan mortalitas maternal. Abortus adalah berakhirnya kehamilan pada atau sebelum kehamilan tersebut berusia 22 minggu. Banyak faktor yang mempengaruhi abortus, salah satunya adalah infeksi yang disebabkan oleh Chlamydia trachomatis, selain itu faktor resiko lain yang mempengaruhi terjadinya abortus adalah usia maternal, paritas, riwayat kejadian abortus pada kehamilan sebelumnya, dan jarak kehamilan. Tujuan penelitian ini adalah untuk mengetahui hungan infeksi Chlamydia trachomatis dengan kejadian abortus spontan. Penelitian ini merupakan studi analitik dengan desain case control yaitu untuk mengetahui infeksi C. trachomatis dengan kejadian abortus spontan. Populasi penelitian adalah semua ibu hamil dengan abortus spontan di RS dr. Rasidin padang dan RSIA Siti Hawa Padang. Teknik pengambilan sampel dengan consecutive sampling yaitu setiap penderita yang memenuhi kriteria inklusi dimasukkan dalam subyek penelitian sampai jumlah sampel tercapai  yaitu sebanyak 50 sampel. Hasil penelitian didapatkan Proporsi kejadian abortus pada sampel positif C. trachomatis yaitu 44,0%. Analisa statistik dengan uji Fisher’s Exact Test menunjukan, terdapat hubungan yang bermakna antara infeksi C.trachomatis dengan kejadian abortus (p<0.05) dengan nilai Odds Ratio (OR) 5,7. Dari hasil penelitian dapat disimpulkan terdapat hubungan antara infeksi C.trachomatis dengan kejadian abortus. Diharapkan untuk penelitian berikutnya melakukan penelitian lebih lanjutan mengenai hubungan faktor resiko maternal dan  infeksi Chlamydia trachomatis  terhadap kejadian abortus spontan dengan metode penelitian yang berbeda dan jumlah sampel yang lebih banyak.
Faktor Risiko dan Luaran Maternal Plasenta Akreta di RSUP Dr. M. Djamil Padang Annissa Qatrunnada; Puja Agung Antonius; Yusrawati Yusrawati
Indonesian Journal of Obstetrics & Gynecology Science Volume 1 Nomor 2 September 2018
Publisher : Dep/SMF Obstetri & Ginekologi Fakultas Kedokteran Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1262.097 KB) | DOI: 10.24198/obgynia.v1n2.94

Abstract

AbstrakTujuan: Penelitian ini bertujuan untuk mengetahui frekuensi kejadian, hubungan faktor risiko, dan luaran maternal dengan plasenta akreta.Metode: Penelitian ini adalah analitik observasional dengan desain cross sectional. Penelitian dilakukan di bagian rekam medis RSUP Dr. M. Djamil Padang dari Januari 2016 sampai Desember 2017 dengan sampel penelitian berjumlah 84 orang yang terbagi dalam 2 kelompok, yaitu kelompok suspek plasenta akreta dan kelompok kontrol.Hasil: Hasil penelitian didapatkan sebanyak 64 orang (4,3%) terdiagnosa suspek plasenta akreta. Terdapat hubungan yang bermakna antara usia, paritas, riwayat seksio sesarea, dan plasenta previa (p<0,05) dengan plasenta akreta. Didapatkan riwayat sectio cesarea ≥ 2 kali merupakan faktor dominan pada plasenta akreta (OR 6,038, 95% CI 2,145−16,995). Terdapat hubungan yang bermakna antara lama rawat >7 hari, butuh transfusi darah, dan histerektomi (p<0,05) dengan plasenta akreta.Kesimpulan: Riwayat sectio cesarea, plasenta previa, usia, dan paritas merupakan faktor risiko plasenta akreta dengan morbiditas berupa lama rawat >7 hari, butuh transfusi darah, dan histerektomi.Risk Factors and Maternal outcomes in Placenta Accretain Dr. M. Djamil Padang General HospitalAbstractObjective: This study aims to determine the frequency of occurrence, association of risk factors, and maternal outcomes with placenta accreta.  Method: This is an observational analytic with a cross-sectional design. This study was conducted in the medical record Dr. M. Djamil Padang General Hospital from January 2016 until December 2017 with total samples of the study were eighty four people and divided into 2 groups, suspected placenta accreta group and control group.Result: The result showed 64 people (4.3%) were diagnosed with suspect placenta accreta. There were significant association between age, parity, prior cesarean section, and placenta previa (p<0.05) with placenta accreta. The dominant factor in placenta accreta is ≥ 2 prior cesarean section (OR 6,038, 95% CI 2,145-16,995). There were significant association between length of stay more than 7 days, need blood transfusion, and hysterectomy (p<0,05) with placenta accreta.Conclusion: Prior cesarean section, placenta previa, maternal age, and parity are risk factors for placenta accreta with maternal morbidity such as length of hospital stay more than 7 days, requires blood transfusion, and hysterectomy.Key words: Placenta accreta, cesarean section, placenta previa 
Small cell neuroendocrine carcinoma of the uterine cervix (SCNEC): a case report and review Puja Agung Antonius; Hariyono Winarto
Jurnal Ilmu Kesehatan Indonesia Vol 2 No 1 (2021): Maret 2021
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1292.711 KB) | DOI: 10.25077/jikesi.v2i1.528

Abstract

Objective: Improving skill and knowledge to diagnose and manage a rare case of small cell neuroendocrine uterine cervical cancer Method: a Case report Result: A 51 years old, para 2, Indonesian woman with chief complaint post-coital vaginal bleeding. Gynecology examination revealed cervical exophytic fragile mass size 3x3x3,5 cm, easily bleeding, with a necrotic part, infiltrated both parametria but not reach the pelvic wall correspond to stage IIB. Initially, the histopathology result from punch biopsy was an adenocarcinoma well-differentiated, with no lymph vascular invasion, DD/ adenosquamous, neuroendocrine tumor. We did the histopathology review continued with immunohistochemistry examination. Immunohistochemistry result showed that although all the sample was not typical, immunohistochemical outward patterns can support morphological features of high-grade neuroendocrine carcinoma, small cell type. We proceed here for chemoradiation therapy. Conclusion: Small cell neuroendocrine carcinoma of the uterine cervix is a rare case. Histopathology and immunohistochemistry examination has an important role to develop the diagnosis. Although the prognosis is poor, adjuvant chemotherapy or chemoradiation was associated with improved survival in patients with advance staged. Keywords: SCNEC, immunohistochemistry, chemoradiation
Invasive epithelial ovarian carcinoma (EOC) at a young age: role of fertility-sparing Puja Agung Antonius; Tricia Dewi Anggraeni
Jurnal Ilmu Kesehatan Indonesia Vol 2 No 2 (2021): Juni 2021
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (437.114 KB) | DOI: 10.25077/jikesi.v2i2.529

Abstract

Objective: Improving knowledge to manage an invasive epithelial ovarian cancer at a young age who expect to preserve their reproductive function Method: a Case report Result : A 26 years old, nulliparity, Indonesian woman with chief complaint abdominal enlargement simultaneous with dyspnoea condition. Physical examination revealed an enlarged abdomen until processus xhypoideus with positive shifting dullness. Gynecology examination found normal uterine size, palpable cystic mass originated from adnexa until navel, mobile. CT whole abdomen showed a cystic solid mass in the pelvic area up to mid abdominal size 17,8 x 10,7 x 18,8 cm accompanied by lymphadenopathy in paraaortic and bilateral inguinal. Ascites and pleural fluid cytology examination results were both positive for malignant cells (metastatic adenocarcinoma). The patient was assessed as advanced staged ovarian cancer and procced for Interval Debulking Surgery (IDS) after 3 cycles of Neoadjuvant Chemotherapy (NACT). Postoperative histopathology examination result was high-grade clear cell ovarian carcinoma Conclusion: Fertility-sparing surgery for invasive epithelial ovarian carcinoma could be chosen for selective young age patients who fulfilled the criteria. Education and informed consent is a must regarding the risk of recurrence and prognosis. Keywords: Invasive EOC, fertility sparing, selection criteria, recurrence, prognosis
Ovarian goiter with papillary thyroid carcinoma: A very rare case Puja Agung Antonius; Dr. dr. Syamel Muhammad, SpOG(K)-Onkogin; Muhammad Zaldy Rasyid Putra; Santy Saberko
Andalas Obstetrics And Gynecology Journal Vol. 6 No. 2 (2022)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.6.2.179-183.2022

Abstract

Struma ovarii is a rare condition, in which thyroid tissue is the predominant element in an ovarian carcinoma. Thyroid tissue may demonstrate the same spectrum of pathological features as in the normal thyroid including benign and malignant changes. The malignant type is very rare, only 5% from all incidents of goiter ovarii. We present a case of papillary thyroid carcinoma arising in a struma ovarii of the right ovary in a 43-year-old female
Profil Kasus pada Ibu Hamil yang Dirawat dengan Covid-19 di RSUP Dr. M. Djamil Padang Periode Januari—Desember 2020 Salsabila Dhiyaa Syifa; Mohamad Reza; Zelly Dia Rofinda; Puja Agung Antonius; Firdawati Firdawati; Biomechy Oktomalio Putri
Jurnal Ilmu Kesehatan Indonesia Vol 3 No 3 (2022): September 2022
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jikesi.v3i3.888

Abstract

Latar Belakang: Coronavirus Disease 2019 (COVID-19) adalah penyakit pada saluran pernafasan yang diakibatkan oleh Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). Virus ini dapat menginfeksi kelompok rentan, termasuk ibu hamil. Penelitian ini bertujuan untuk mengetahui gambaran profil kasus pada ibu hamil yang dirawat dengan COVID-19. Objektif: Penelitian ini bertujuan untuk mengetahui gambaran profil kasus pada ibu hamil yang dirawat dengan COVID-19 di RSUP Dr. M. Djamil Padang Periode Januari—Desember 2020. Metode: Penelitian ini menggunakan metode deskriptif dengan desain cross-sectional di RSUP Dr. M. Djamil Padang dengan jumlah sampel sebanyak 136 ibu hamil dengan COVID-19 pada tahun 2020. Data yang digunakan berupa data sekunder dari rekam medis dengan menggunakan teknik total sampling. Hasil: Ibu hamil yang terpapar COVID-19 memiliki gejala ringan (95,6%), berada pada usia tidak berisiko (83,8%),berada pada kehamilan trimester III (87,5%), dan terpapar tanpa komorbid (81,6%). Didapatkan juga peningkatan kadar NLR dan D-Dimer, banyak yang mendapat tindakan berupa sectio caesarea (64,7%), dan adanya kematian 3 ibu (2,2%). Kesimpulan: Sebagian besar ibu hamil dengan COVID-19 memiliki gejala ringan, berada pada usia tidak berisiko (usia 20—35 tahun), hamil pada trimester III, terpapar tanpa komorbid, memiliki peningkatan NLR dan D-Dimer, dilakukan tindakan sectio caesarea, dan tidak banyak terjadi kasus kematian.
Myxoid ovaries that resemble malignancy in young girls: a case report Fajriman Fajriman; Puja Agung Antonius; Syammel Muhammad
Andalas Obstetrics And Gynecology Journal Vol. 7 No. 2 (2023)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.7.2.473-478.2023

Abstract

In the most recent publications on Mayer-Rokitansky-Küster-Hauser (MRKH) Myxoma is a benign tumor that generally occurs in the heart, soft tissue, muscle, skin and bone. But in this case, we present myxoma that occurs primarily in the ovary. Ovarian myxsoma is a rare benign tumor.In this case report, it was found that a 12-year-old girl was brought by her parents to the M. Djamil Hospital in the city of Padang, West Sumatra. After performing the gynecological physical examination and ultrasonography, there was a hypoechoic mass with an indeterminate solid part of the right adnexa, which was suspected of being an ovarian malignancy. Then it was decided to carry out a procedure in the form of a conservative surgical staging laparotomy. The results of the Anatomical Pathology examination confirmed the myxoid ovarian appearance and the patient was decided for regular monitoring. 
Choriocarcinoma with Pulmonary and Spinal Metastases : A Case Report Fardani Putra Syafar; Syammel Muhammad; Puja Agung Antonius
Andalas Obstetrics And Gynecology Journal Vol. 7 No. 2 (2023)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.7.2.495-501.2023

Abstract

Background : Choriocarcinoma is extremely malignant tumor contains of anaplastic trophoblast and prominent hemorrhage, necrosis, and vascular invasion. Choriocarcinoma is a rare, aggressive neoplastic type of trophoblastic disease. This condition grow rapidly and can metastasize to the lung and liver. There are few cases of choriocarcinoma metastases to the spine that have been reported.Case Report : A 28-year-old woman with complaints of haemoptoe and shortness of breath. Previously the patient complained of not feeling the sensation for defecation and micturition. The patient had been diagnosed with choriocarcinoma since 3 years ago, refused to have a hysterectomy and had received chemotherapy 12 times in the first year with choriocarcinoma, but dropped out of chemotherapy in the second year, then came with a worsening condition a year later. The results of the chest x-ray and lumbar MRI showed suspicion of metastases to the lungs and spine. The patient was continued with chemotherapy with paclitaxel and carboplatin and was monitored with periodic beta HCG evaluation. Choriocarcinoma a have different prognoses depending on stage and onset. In these patients, based on FIGO staging, she has reached stage IV and also suspected chemotherapy-resistant Gestational Trophoblastic Neoplasia (GTN), worsened by disobedience to previous treatment. Many patients with GTN require multiple regimens with or without surgery to achieve complete remission.
Personalized Medicine on Muscinous Ovarian Cancer Effendy Fila; Antonius Puja Agung
Jurnal Health Sains Vol. 5 No. 3 (2024): Journal Health Sains
Publisher : Syntax Corporation Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Ovarian cancer (OC), ranking third among gynecological cancers, poses a significant health concern with the worst prognosis and highest mortality rate. The global incidence, as per 2018 data, reached 295,414 cases, constituting 3.4% of women's cancer cases. The prevalence has notably risen in Asian countries, including Singapore and Indonesia. This report highlights two cases from Dr. M. Djamil, emphasizing the importance of personalized medicine (PM) in treating OC. PM, leveraging genomic information, aids in tailoring treatments for individual patients. The standard treatment involves cytoreductive surgical debulking and platinum-based chemotherapy. Notably, PM has shown promise in addressing specific genetic mutations, such as BRCA1 and BRCA2, prevalent in breast and ovarian tumors, enabling more targeted therapeutic approaches and enhancing treatment outcomes.
PERITONEAL TUBERCULOSIS IN YOUNG AGE LADY MIMICKING GYNECOLOGY MALIGNANCY : A CASE REPORT Lusi Jelita Sari; Puja Agung Antonius; Syamel Muhammad
Andalas Obstetrics And Gynecology Journal Vol. 8 No. 1 (2024)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.8.1.653-659.2024

Abstract

Background : Peritoneal tuberculosis is one of the most challenging forms of extrapulmonarytuberculosis to diagnose. Extrapulmonary TB is very difficult to diagnose because of its non-specific signs and symptoms, thus it sometimes leads to a diagnosis of gynaecologicalmalignancy such as advanced ovarian carcinoma.Case Report : A teenage girl, 12 years old, with a chief complaint of intermittent abdominalpain since the last 1 month. There was no history of an enlarged abdomen, fever and weightloss. Ultrasound examination revealed an irregular adnexal mass suggesting an ovarianmalignancy with other possibilities of an infectious process. Diagnostic laparoscopy andperitoneal biopsy were performed on the patient. Intraoperatively, multiple friable nodular-mylar peritoneal masses with abdominopelvic attachments and fibrin fibres and white vesicleswere found on the entire surface of the genitalia, peritoneum, and intestines. A mass biopsywas performed with histopathological results showing peritoneal tuberculosis. Currently, thepatient is undergoing anti-tuberculosis drugs (OAT) treatment.Discussion : The diagnosis of this disease is difficult to establish. Symptoms are highlyvariable and non-specific and can lead to the wrong tumour pathology. The clinicalcharacteristics are dominated by changes in general condition, abdominal pain and transitdisorders, as well as masses (20 to 25%). The gold standard for definitive PTB diagnosisremains laparoscopy with peritoneal biopsy and subsequent pathological or microbiologicalconfirmation. Yellow/white nodules in the peritoneum observed on the patient's laparoscopicimages are the hallmark of wet peritoneal TB. Omental thickening and abdominal cocoon withmatted small bowel are other classic laparoscopic findings for peritoneal TB.Conclusion : PTB has similar characteristics to peritoneal carcinoma, which makes diagnosisdifficult for clinicians. Early and correct diagnosis of PTB helps to initiate medical managementquickly and helps reduce morbidity and mortality.
Co-Authors Anavelda, Aura Putri Andani Eka Putra Annissa Qatrunnada Anugrah, Mutia Paramadita Azmira, Nazurah Caesar Muhammad Wijaya Defrin, Defrin Deni Heryanto Dia Rofinda, Zelly Dia Dimba, Modester Effendy Fila Elmatris, Elmatris Erlina Rustam Fadila, Zurraya Fajriman Fajriman Fajriman, Fajriman Fardani Putra Syafar Firdawati Firdawati Firdawati, Firdawati Fitrayeni Fitrayeni Fitria, Henni Harbaindo, Shavira Quincy Hariyono Winarto Ida Rahmah Burhan Insani, Aldina Ayunda Irfan Kurnia Karmia, Hudila Rifa Karsa, Salsa Bila Kurnia, Irfan Linosefa Linosefa Lusi Jelita Sari Meuthia, Susan Mohamad Reza Muhammad Zaldy Rasyid Putra Muhammad, SpOG(K)-Onkogin, Dr. dr. Syamel Muhammad, Syammel Netti Suharti, Netti Putri, Biomechy Oktomalio Rahman, Chairani Rasyid Putra, Muhammad Zaldy Rinal Effendi Rini Rustini Saberko, Santy Salsabila Dhiyaa Syifa Santy Saberko Sari, Lusi Jelita Savannah, Aisha Sugeng, Santoso Syafar, Fardani Putra Syamel Muhammad Syammel Muhammad Syammel Muhammad Tricia Dewi Anggraeni Virgusrudhina, Mitra Wenny Nursa Octarina Wijaya, Caesar Muhammad Yusrawati Yusrawati Yusri, Elfira