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Contact Name
Rachmat Hidayat
Contact Email
dr.rachmat.hidayat@gmail.com
Phone
+6288225053819
Journal Mail Official
sriwijayajournalopthalmology@gmail.com
Editorial Address
Dr. Moh Ali street Palembang, 30126
Location
Kab. ogan ilir,
Sumatera selatan
INDONESIA
Sriwijaya Journal of Ophthalmology
Published by Universitas Sriwijaya
ISSN : -     EISSN : 27229807     DOI : https://doi.org/10.37275/sjo.v2i2.35
Core Subject : Health, Science,
Sriwijaya Journal of Opthalmology (SJO) is a peer-reviewed, scientific publication that welcomes the submission of original, previously unpublished manuscripts directed to ophthalmologists and visual science specialists describing clinical investigations, clinical observations, and clinically relevant laboratory investigations. Sriwijaya Journal of Opthalmology (SJO) publishes original article, case report and review article related opthalmology.
Articles 90 Documents
Management of Clinically Significant Macular Edema Elisa Taurisia; Ramzi Amin; AK Ansyori
Sriwijaya Journal of Ophthalmology Vol. 3 No. 1 (2020): Sriwijaya Journal of Ophthalmology
Publisher : Department of Opthalmology, Faculty of Medicine, Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (221.813 KB) | DOI: 10.37275/sjo.v3i1.23

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Introduction: Macular edema is the most common cause of visual impairment in NPDR. Macular edema occurs due to increased perifoveal capillary permeability resulting in fluid accumulation in the macular area. Control of blood sugar levels is an important factor in the management of diabetic retinopathy because it can reduce the risk of progression of retinopathy, decreased vision and macular edema. Currently, focal photocoagulation argon lasers are the only proven long-term treatment for diabetic macular edema. Case presentation: Reported case of a 55-year-old woman, address outside the city, came to the Dr. Mohammad Hoesin General Hospital Palembang eye clinic with complaints of blurred vision since ± 6 months ago. three days ago, the patient went to an internal medicine clinic and was said to have high blood sugar and blood pressure. The views of both sufferers' eyes are increasingly blurred. The treatment chosen for this patient was intravitreal anti-VEGF (bevacizumab) injection in the right and left eye to reduce vascular permeability thereby reducing macular edema. 1-time bevacizumab injection has only a short-term optimal effect so re-injection is needed at 4-6 weeks intervals. Conclusion: A clinically significant case of macular edema (CSME) has been reported that is treated with intravitreal anti-VEGF combined with focal photon photocoagulation laser. The patient's final vision 1 week after the focal photocoagulation argon laser was performed showed improvement.
Management of Submacula Bleeding with Pneumatic Displacement Shaelva Lassa Sabatini; AK Ansyori; Ramzi Amin
Sriwijaya Journal of Ophthalmology Vol. 2 No. 1 (2019): Sriwijaya Journal of Ophthalmology
Publisher : Department of Opthalmology, Faculty of Medicine, Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (201.984 KB) | DOI: 10.37275/sjo.v2i1.26

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Introduction. Submacular hemorrhage is defined as the presence of blood in the potential space between retinal pigment epithelium (RPE) and neurosensory retinal in the macula. Pneumatic displacement is one of the management procedures that is shifting the bleeding under the macula by injecting gas. The purpose of writing this case report is to report Sub-macula Bleeding cases which are managed with Pneumatic Displacement. Case Presentation. A 55-year-old woman, housewife, was living outside the city, came with complaints of a sudden blurred left eye since 2 weeks ago. At the ophthalmological examination, 612 pH (-) right eye vision and 1/300 left eye vision were obtained. On examination of the anterior segment in the right and left eye the lens is cloudy with grade I nuclear morphology. The image of the right eye fundoscopy is within normal limits, whereas in the left eye a macula is found: reflex fovea (-) blood (+). The choice of therapy in this patient is carried out by Pneumatic Displacement by injecting C3F8 gas, which aims to shift the bleeding under the macula by injecting gas. Conclusion. Pneumatic Displacement is a simple procedure, not too invasive, and the risk of intraocular complications is smaller. Pneumatic Displacement aims to shift blood from under the macula to other parts of the retina that are less vital for vision.
Management of Diabetic Retinopathy Nova Herdana; AK Ansyori; Ramzi Amin
Sriwijaya Journal of Ophthalmology Vol. 1 No. 2 (2018): Sriwijaya Journal of Ophthalmology
Publisher : Department of Opthalmology, Faculty of Medicine, Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (200.562 KB) | DOI: 10.37275/sjo.v1i2.27

Abstract

Introduction. Diabetic retinopathy (RD) is one of the most common complications of diabetes mellitus, and is a major cause of blindness in patients aged 20-64 years worldwide. The main principle of the management of RD is to prevent, inhibit and overcome complications that occur. Vitrectomy, laser photocoagulation, intravitreal anti VEGF injection become modalities in RD therapy. If PDR has occurred, vitreous hemorrhage can occur or the retina is attracted by proliferation tissue, vitrectomy should be performed. Case Presentation. The patient is a 52-year-old man who came with the main complaint that both eyes have blurred slowly since ± 6 months ago. Blurred vision is not accompanied by red eyes, there is smoke-like vision. In the past the history of the disease obtained a history of DM 15 years of irregular control and hypertension of 3 years with regular control, a history of spectacles present. The ophthalmological examination of the right eye revealed a vision of 6/30 pH (-), TIOD within normal limits, and a grade II nuclear cataract in the lens. Right eye fundoscopy revealed decreased foveal reflexes and exudates in the macula, dot, blot, flame-shaped bleeding in 4 quadrants of the retina, exudate, venous beading, micro-aneurism. Management in these patients is pars plana vitrectomy, endolaser, and intravenous OS anti-VEGF injection under general anesthesia. Whereas the right eye was intravitreal photocoagulation laser and anti-VEGF laser (done 2 weeks before). Conclusion. A case of advanced left eye PDR with severe NPDR and right eye DME and grade II nuclear cataracts has been described in both eyes. Patients treated with laser photocoagulation in the right eye. In the left eye pars plana vitrectomy, endolaser, and intravitreal bevacizumab injection. Sharp vision of the left eye progressed postoperatively.
Retinometry : a Literature Review Febrina Art; Ramzi Amin; AK Ansyori
Sriwijaya Journal of Ophthalmology Vol. 1 No. 1 (2018): Sriwijaya Journal of Ophthalmology
Publisher : Department of Opthalmology, Faculty of Medicine, Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (147.534 KB) | DOI: 10.37275/sjo.v1i1.31

Abstract

Sharp vision is a major concern in cataract cases. Sharp improvement in vision is the expected outcome of the management of cataract cases, namely by operative measures. Before surgery, there are several ophthalmological examinations that must be performed. Quantitative instruments have been developed to determine the visual potential of eyes that experience turbidity of refractive media. One examination that can be done is a retinometry examination that is the examination of the sharp potential of vision with a retinometer. Retinometry is a process of measuring sharp eyes using a retinometer to determine the potential for sharp eyesight. Retinometer is one tool that uses the principle of interference fringes to assess the patient's sharp vision through a cloudy lens. On a retinometer, a light source is split into two rays which then enter the least turbid lens area so that interference grating is formed on the retina. The lattice can have a vertical, horizontal or oblique meridian orientation
Stargardt's Disease : Case Report Dian Ariani; AK Ansyori; Ramzi Amin
Sriwijaya Journal of Ophthalmology Vol. 1 No. 1 (2018): Sriwijaya Journal of Ophthalmology
Publisher : Department of Opthalmology, Faculty of Medicine, Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (207.13 KB) | DOI: 10.37275/sjo.v1i1.32

Abstract

Introduction. The Stargardt disease is a frequent macular dystrophy and the most common cause of decreased central visus in adults below 50 years. This condition is caused by the presence of mutations in the ABCA4 gene, located in the chromosome chain 1 short sleeve, which encode the ATP-binding cassette (ABC) protein transporter expressed by the outer trunk cell segment. Case Presentation. A man, 59 years old, civil servants, was living in the city, came to the eye Polyclinic RSMH on February 4, 2016. From anamnesis, main complaint of the right eye was view blurred since 2 years ago. The history of the illness since ± 2 years ago, the sufferer complained the right eye view blurred slowly, the longer the more blurred. Often glare (+), the sufferer also complains to see black spots, such as enclosed curtains (-). Conclusion. A case of Stargardt disease has been reported in a 58-year-old male. Patients come with complaints of blurry vision slowly in both eyes. On posterior segment examination, a picture of atrophy in the macula that typically leads to Stargardt disease. Additional examination of OCT also showed a stretch of RPE depletion. Supportive therapy such as correction with low vision aids or the provision of sun protective glasses can help in the daily lives of patients.
Relationship Between HbA1c Level with Retinal Nerve Fiber Layer Thickness in Diabetic Retinopathy Febrina Art; AK Ansyori; Ramzi Amin
Sriwijaya Journal of Ophthalmology Vol. 2 No. 2 (2019): Sriwijaya Journal of Ophthalmology
Publisher : Department of Opthalmology, Faculty of Medicine, Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (153.013 KB) | DOI: 10.37275/sjo.v2i2.34

Abstract

Abstract Background: Diabetes mellitus (DM) have a direct effect to retinal neural tissue. Diabetic retinopathy slowly proggress with reserved visual acuity and no symptoms in early stage. Retinal nerve fiber layer thickness significantly decrease in type 2 diabetes mellitus patients related to glycemic blood level. Purpose: To analyze the relationship between HbA1c level and retinal nerve fiber layer thickness in diabetic retinopathy patients. Methods: A cross sectional analytical study was conducted in RSUP dr. Mohammad Hoesin Palembang from October 2017 until March 2018. Sixty eight type 2 diabetes mellitus patients consist of various grade of diabetic retinopathy. Measurement of HbA1c level was performed on these samples and retinal nerve fiber layer thickness was measured by Optical Coherence Tomography (OCT). Results: There is a significant relationship between duration of DM with RNFL thickness (p = 0,002). There is a significant relationship between hypertension with RNFL thickness (p = 0,007). There is a significant relationship between HbA1c level with RNFL thickness in all quadrants (superior, nasal, inferior quadrants p = 0,000, temporal quadrant p = 0,011). The most important factor of RNFL thinning in superior, nasal and inferior quadrants is HbA1c level (superior and nasal adjusted p value 0,002, inferior adjusted p value 0,002) while in temporal quadrant is hypertension (adjusted p value 0,042). Conclusion: There is a significant relationship between HbA1c level with RNFL thickness in all quadrants in which the patients with HbA1c > 7% have a higher risk of thinner RNFL compared to patients with HbA1c ≤ 7%.
The Relationship Between Immunoglobulin E Serum Levels And Age-Related Cataract Meidina Rahmah; Alie Solahuddin
Sriwijaya Journal of Ophthalmology Vol. 2 No. 2 (2019): Sriwijaya Journal of Ophthalmology
Publisher : Department of Opthalmology, Faculty of Medicine, Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (187.838 KB) | DOI: 10.37275/sjo.v2i2.35

Abstract

ABSTRACT Objective: To determine the relationship of serum IgE levels and age-related cataract at the Special Eye Hospital in Palembang. Methods: An observational study with cross-sectional design study was undertaken in October 2018 to May 2019 at the Special Eye Hospital in Palembang. There were 86 patients who met the inclusion and exclusion criteria. The independent variable in this study is the level of serum immunoglobulin E and the dependent variable is senile cataract. The data analysis has been done with diagnostic research by SPSS version 20.0 (SPSS, Inc Chicago, Illinois). Results: Thirty five people suffered from senile cataracts and fifty one people did not suffer from cataracts. The mean IgE level in senile cataract patients was 5.129 ± 1.588 ng /mL while in patients without cataracts it was 5.001 ± 1.564 ng/mL. There was no difference in IgE levels between senile cataract patients and patients without cataracts (p = 0.891). With statistical analysis using the ROC curve it was found that the IgE concentration cut off point was 5.046 ng/mL. There were 54.3% of senile cataract patients and 51% of patients without cataracts who had IgE levels > 5.046 ng/mL. Patients with IgE levels > 5.046 had an almost equal risk of senile cataracts compared to patients with IgE levels <5.046 (PR = 1.142 (CI95% 0.482 - 2.705; p = 0.935). Conclusion: There is no significant relationship between IgE levels and the incidence of senile cataracts.
The Effect of Aloe Vera Extract to Extensive Lesion and Expression of Transforming Growth Factor (TGF-β) on Alkaline Chemical Trauma Cornea Model Fahcreza; Elsa Iskandar; Rachmat Hidayat; Petty Purwanita; Anang Tribowo; Riani Erna
Sriwijaya Journal of Ophthalmology Vol. 1 No. 2 (2018): Sriwijaya Journal of Ophthalmology
Publisher : Department of Opthalmology, Faculty of Medicine, Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (236.279 KB) | DOI: 10.37275/sjo.v1i2.36

Abstract

Abstract Background: Chemical trauma to the cornea is an emergency condition of the eye that requires early diagnosis and good treatment. Alkaline have ability to saponify fatty acids in cells and cell membranes which can make penetration into the stroma and destroy proteoglycans and collagen in cells. Aloe vera (AV) contains several active substances that are reported to have anti-inflammatory, immunomodulatory, and wound healing effects. AV has been reported to accelerate the healing process of corneal epithelial defects by increasing fibroblast proliferation, collagen production and growth factor production. This study aims to determine the difference between the effect of aloe vera extract with a concentration of 10%, 20%, 40% and BSS on the healing of extensive corneal lesions in white wistar rats alkaline trauma models. Method: This study was an experimental study with a pre and posttest only with control group design in vivo approach to 30 Wistar white rats which were divided into 5 treatment groups for 3 days. Comparative analysis of effectiveness using the ANNOVA test or the Kruskal Wallis test and continued by the post hoc test. Results: Based on the one way ANOVA test there was a statistically significant difference in effectiveness between the five treatment groups on the percentage of corneal wound healing area and TGF-β expression with an assessment of p = 0,000 each. The administration of alloevera (AV) concentration of 20% had a significant difference in percentage of healing of corneal lesions and TGF-β expression compared with other treatment groups with p = 0,000 each. Large differences in the area of corneal lesions in the 40% AV group were -0.45 in the BBS group, 0.146 in the 10% AV group, 0.493 in the 20% AV group. The difference in the AV group 10% was 0.30 in the BBS group, -064 in the AV group 20%, and -0.14 in the AV group 40%. However, TGFβ expression in the normal control group that did not receive treatment was 54.94 (53.21-56-12). TGFβ levels in the BSS group were 10.44, the 10% aloe vera group was 25.43, 47.99 for the 20% aloe vera group and 37.95 for the 40% aloe vera group. Conclusion: There is a difference between the effect of aloe vera extract with concentrations of 10%, 20%, 40% and BSS on the extensive healing of corneal lesions in white wistar rats with alkaline chemical trauma models.
P16INK4A Expression on Retinoblastoma at Mohammad Hoesin Hospital Palembang Sri Tanty Fuji A Harahap; Ika Kartika; Rusdianto
Sriwijaya Journal of Ophthalmology Vol. 1 No. 1 (2018): Sriwijaya Journal of Ophthalmology
Publisher : Department of Opthalmology, Faculty of Medicine, Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (299.166 KB) | DOI: 10.37275/sjo.v1i1.37

Abstract

ABSTRACT Background: Retinoblastoma is a malignant tumor with an average incidence of one case per 15,000-20,000 births. Retinoblastoma is associated with the presence of the Rb1 gene mutation which has role in preventing DNA replication. Various studies have linked the existence of p16INK4A as a CDK inhibitor that inhibits Cyclin D and CDK4 so that the activity of the Rb1 gene is inhibited. Objective: This study was conducted to identify p16INK4A expression on Retinoblastoma at Mohammad Hoesin Hospital. Methodology: A descriptive study used on the paraffin blocks of 14 cases Retinoblastoma in Mohammad Hoesin Hospital Palembang from January 2014- July2018. Histopathologic feature were examined with Hematoxylin- Eosin staining and immunohistochemical were examined with p16INK4A antibody. Data were analyzed using SPSS version23 to identify histopathological feature of p16INK4A expression in Retinoblastoma Results: Most retinoblastoma samples in this study were expressed in p16INK4A (92.86%). The degree of differentiation of retinoblastoma with the largest number at Mohammad Hoesin Hospital is moderately differentiated (57.14%). Retinoblastoma invasion of the optic nerve and sclera in the study at Mohammad Hoesin Hospital, respectively at 57.14% and 42.86%. Conclusion: Most retinoblastoma samples in this study were expressed in p16INK4A.
Correlation Between Ocular Rigidity With Intraocular Pressure In Patient With Type 2 Diabetes Mellitus Roland Iqbal; Prima Maya Sari; Ramzi Amin; Fidalia
Sriwijaya Journal of Ophthalmology Vol. 2 No. 1 (2019): Sriwijaya Journal of Ophthalmology
Publisher : Department of Opthalmology, Faculty of Medicine, Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (191.056 KB) | DOI: 10.37275/sjo.v2i1.38

Abstract

ABSTRACT Introduction and Objectives: Diabetes mellitus (DM) is known to have a biomechanical effect on tissue. High blood glucose concentrations that lead to increased production of free radical intermediates causes ocular rigidity (OR) changes. This change can effect intraocular pressure (IOP) in patients with type 2 DM. This study to determine correlation between ocular rigidity with IOP in patients with type 2 DM. Methods: A cross-sectional study with a correlation test design of OR with IOP in type 2 DM patients was conducted in RSUP dr. Mohammad Hoesin Palembang from January until June 2018. Eighty eye samples consist of 60 type 2 DM and 20 control group. IOP examination was performed using a Goldmann applanation tonometer and OR measurements using schiotz tonometer with two loads then assessed in Friedenwald differential tables. Result: There was a significant correlation between diabetic retinopathy and OR (p=0,000). There was a significant correlation between OR and IOP in NPDR and PDR group (p=0,000). There was a significant relationship between patient age with OR and IOP (p<0,05). Conclusion: There is a significant correlation between ocular rigidity and IOP in people with type 2 DM.