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Mohammad Saifur Rohman
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Heart Science Journal
Published by Universitas Brawijaya
ISSN : 27219976     EISSN : 27219984     DOI : http://dx.doi.org/10.21776/ub.hsj.2020.001.01
Core Subject : Health, Science,
Health Professions Immunology & microbiology Medicine & Pharmacology
HEART SCIENCE is the official open access journal of Brawijaya Cardiovascular Research Center, Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia. The journal publishes articles three times per year in January, May, and September. The journal is a peer reviewed publication and accepts articles for publication from across the world. HEART SCIENCE accepts and publishes articles in the English language only. The primary goal of this journal is to publish clinical and basic research relevant to cardiovascular medicine. The journal covers the following topics: clinical cardiology, interventional cardiology, intensive and acute cardiovascular care, vascular diseases, non-invasive cardiology, pediatric cardiology, cardiac nuclear medicine imaging, arrhythmia, cardiac prevention and rehabilitation, and cardiac surgery. Animal studies are also considered for publication in HEART SCIENCE. To serve the interest of both practicing clinicians and researchers, the journal provides platform or forum for research scholars, intellectuals, and cardiologists to reveal their views and research work for dialogue, education, and interaction to the entire world. HEART SCIENCE publishes original research, reviews, brief reports, case reports, case series, editorial, and commentary. HEART SCIENCE also publishes the special issues and abstracts of papers presented at the annual meeting of the Cardiological Society of Malang.
Arjuna Subject : Kedokteran - Cardiology and Cardiovascular Medicine
Articles 302 Documents
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Fever-Induced Brugada-Pattern Electrocardiogram Nugraha, Yudha Tria; Prasetya, Indra; Martini, Heny; Rizal, Ardian
Heart Science Journal Vol. 5 No. 1 (2024): Inflammation and Cardiovascular Disease
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub/hsj.2024.005.01.7

Abstract

Background: The Brugada syndrome is a type of cardiac arrhythmia frequently overlooked because of the dynamic character of the condition. Because it tends to progress into ventricular arrhythmias, it is a disorder that, if left untreated, carries the risk of being deadly. Not only is it essential for the practicing clinician to understand the situations that can disclose the concealed Brugada syndrome, but it is also essential for patients to understand these circumstances so that they can be educated to seek medical assistance quickly. This study aimed to describe the diagnosis and management of fever-induced Brugada pattern electrocardiogramCase presentation: Male in his 42-year-old with a history of intermittent fever for four days before hospital admission. High-degree fever was only relieved by taking antipyretics and was accompanied by nausea and muscle and joint pain. Upon arrival at the emergency department, he denied any complaints of chest pain or discomfort, shortness of breath, orthopnea, PND, leg swelling, palpitation, or syncope. A chest radiograph showed normal cardiac and pulmo (Figure 1); a first electrocardiogram showed Sinus Rhythm, HR 112 bpm, regular, FA normal, HA normal, P wave normal, PR interval 160 msec, QRS 80 msec, QTc 326 msec, Coved ST elevation at lead V1 (1 mm), V2 (3 mm), T inversion at lead V1-V2, suggesting sinus tachycardia with type II Brugada pattern.Conclusion: A Brugada pattern can be exposed to several stimuli, but fever is particularly potent. To assist urgent or emergency follow-up in cardiology, Emergency physicians must be informed of specific ECG findings based on the patient's clinical risk factors. The emergency doctor must be able to tell the difference between this pattern and a typical variation of RBBB, as a delayed diagnosis can have dire consequences.
Cracking the Case of the Cryptic Coronary: Novel Diagnostic Strategies for Anomalous RCA Originating from Mid-LAD Indrihapsari, Pratiwi; Satrijo, Budi
Heart Science Journal Vol. 5 No. 2 (2024): Challenges in the Management of Congenital Heart and Structural Heart Diseases
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub/hsj.2024.005.02.15

Abstract

Background:Coronary artery anomalies are typically congenital, though they may remain undetected until routine cardiac catheterization is performed. With a detection rate of only 1.3%, these anomalies often go unnoticed. In rare cases, the right coronary artery may originate from the left coronary system, but this anomaly is generally benign, provided the vessel does not traverse the aorta and pulmonary artery.Case Illustration: A 55-year-old male patient was diagnosed with NSTEMI and underwent coronary angiography. However, the medical team was unable to cannulate into the right coronary ostium despite multiple attempts. The left coronary ostium was located in the left sinus of Valsalva. Selective left coronary arteriography revealed normal courses of the left main and LAD but identified a critical stenosis in the LCx and a possible CTO at the RCA ostium. The patient received a stent in the LCx and returned the following month for another angiography, during which he received a stent in the proximal LAD. However, during cine angiography, it was found that the patient had an anomalous RCA that originated from the mid-portion of LAD, coursing anteriorly to the pulmonary artery, and down to the right atrioventricular groove. Subsequent CCTA confirmed the RCA's origin from the mid-LAD.Conclusion:The report uncovers a unique occurrence where the RCA originates from the mid of the LAD. Appreciation to the integration of coronary CTA, a non-invasive imaging method, it is now feasible to conduct a comprehensive examination of the heart and its intricate vascular network. This, in turn, enables the development of effective surgical and interventional cardiovascular therapies. In a medical environment, this cutting-edge technology is particularly valuable for detecting and assessing coronary abnormalities.
Tailoring Management of May-Thurner Syndrome : Case Comparison Suprapta, Aloysius Yuwono; Kurnianingsih, Novi; Elizabeth Damanik, Gracelia Ruth
Heart Science Journal Vol. 5 No. 3 (2024): The Science and Art of Revascularization in Acute Coronary Syndrome
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub/hsj.2024.005.03.15

Abstract

BACKGROUND: May-Thurner syndrome (MTS) is a post-thrombosis syndrome (PTS) of the lower extremity. This disorder results from compression and/or irritation from adjacent crossing the right common iliac artery to the left iliac venous. In this report, we present two management comparisons of patients with left lower DVT with consideration of MTS.CASE ILLUSTRATION: A 49-year-old male soldier presented with chronic unilateral left leg edema and a mild clinical presentation for 9 months. Previous Doppler ultrasonography (DUS) revealed a thrombus in the left venous femoralis. Anticoagulant was given for six months. DUS and CT venography following anticoagulant treatment revealed a thrombus in the left venous femoralis. Venography revealed entire blockage of the left common femoral and left iliac veins, with adequate collateral flow. PTV was attempted twice and failed both times. The patient was following a conservative therapy (walking exercise and stocking compression) that yielded positive outcomes. A 53-year-old male soldier has had unilateral left leg edema for three years, which has increased during the previous three months with ulceration and active bleeding.Previous Doppler ultrasonography revealed a thrombus in the left iliac externa. Anticoagulants and compression stockings were given for eight months, but the symptoms persisted. CT and venography revealed a complete blockage from the left popliteal vein to the iliac vein. Femoral crossover bypass surgery yielded favorable results.CONCLUSION: Clinically moderate MTS demonstrated fair results with conservative treatment, whereas clinically severe MTS showed superior results with bypass surgery.
Neutrophil-Lymphocyte Ratio value as a predictor of Troponin Elevation in patients with Non-ST Segment Elevation Acute Coronary Syndrome zunardi, Lutfi hafiz; Anjarwani, Setyasih; Prasetya, Indra; Rahimah, Anna Fuji
Heart Science Journal Vol. 5 No. 1 (2024): Inflammation and Cardiovascular Disease
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub/hsj.2024.005.01.2

Abstract

Acute coronary syndrome (ACS) is a prominent contributor to mortality and morbidity on a global scale, consistently ranking within the top five primary causes. Inflammation is one of the many elements that have a role in the pathophysiology of the development and destabilization of plaque atherosclerosis in ACS. Troponin is a component of a biomarker that signals damage to the heart muscle in ACS patients; however, at the present time, not all medical facilities are able to perform troponin testing. An acute myocardial infarction begins with an initial inflammatory process that generates proinflammatory cytokines at the cellular level. This can be evaluated by the NLR through peripheral blood tests. The NLR as an indication of systemic inflammation has been demonstrated to be associated with poor clinical outcomes, an increased risk of complications, and mortality in ACS patients. In addition, several studies showed that the NLR has prognostic value in patients with ACS. The NLR is a mix of inflammatory markers, which can be a predictor of increased troponin in cases of non-ST segment elevation acute coronary syndrome (NSTEACS) in an emergency room.
The Relationship Between Cha2ds2-Vasc Scores And The Degree of TIMI Flow in Patients With Acute St-Segment Elevation Myocardial Infarction Who Underwent Primary Percutaneous Coronary Intervention at Dr. Saiful Anwar Malang Aji, Bayu; Widito, Sasmojo; Anjarwani, Setyasih; Kurnianingsih, Novi; Ruspiono, Evit
Heart Science Journal Vol. 5 No. 2 (2024): Challenges in the Management of Congenital Heart and Structural Heart Diseases
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub/hsj.2024.005.02.10

Abstract

Background: Suboptimal reperfusion of the compromised myocardium in the area of the culprit coronary arteries is one of the main problems associated with primary PCI that need reliable risk stratification methods to accurately predict the occurrence of decreased TIMI flow given its complex pathophysiology. Some parameters are included CHA2DS2-VASc score.Objective: To understand the relationship between CHA2DS2-VASc and the decreased TIMI flow in STE-ACS patients who had underwent primary PCI at RSUD dr. Saiful Anwar Malang.Material and Methods: The study was cohort retrospective with the inclusion criteria being all STE-ACS patients who underwent primary PCI in RSUD Dr. Saiful Anwar Malang from January 2018 – August 2023. Patients were assigned to TIMI flow grade <3 group (N =169) and TIMI flow grade 3 (N = 677) according to TIMI Flow degree after primary PCI. All the patient’s angiogram were evaluated for TIMI score and CHA2DS2-VASc score is based on a guideline. We concluded data in SPSS program and used the Spearman test and p value of .05 was considered as significant.Result: From a total sample of 846 patients, the correlation between STE-ACS onset and TIMI flow indicates that a higher number of patients with STE-ACS onset <12 hours was found in the TIMI flow <3 and 3 groups (p=0.000). The cutoff CHA2DS2 VASC score's sensitivity and specificity values were ascertained using ROC analysis with cut off value 2.5. The incidence of decreased TIMI flow rate was more significant in the CHA2DS2-VASc ≥3 group with DM (+) and age ≥64 (OR value 0.156, p=0.000) than in the CHA2DS2-VASc ≥3 group without DM and age < 64. With an OR value of 2.94 (p=0.000), Killip class > 2 is another powerful predictor of lower TIMI flow.Conclusion: The only variables in the CHA2DS2-VASc score component that are most strongly associated with the risk of reducing the degree of TIMI flow are DM, age, and Killip class.
Successful Emergency Percutaneous Coronary Intervention of Challenging Unprotected Left Main Coronary Artery Disease Patient: How to Prepare and Optimize Suprayoga, Imam Mi'raj; Rohman, Mohammad Saifur; Martini, Heny; Satrijo, Budi
Heart Science Journal Vol. 5 No. 3 (2024): The Science and Art of Revascularization in Acute Coronary Syndrome
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub/hsj.2024.005.03.11

Abstract

Background: Myocardial infarction (MI) due to unprotected left main coronary artery disease (ULMCAD) is a relatively uncommon presentation. It represents as the anatomical subset of coronary artery disease (CAD) with the highest risk of atherosclerotic obstructive CAD. In the setting of acute MI, the treatment options are limited in this particular condition. Major advances in the field of PCI have made PCI as a viable option for patients with ULMCAD who are equally suited for CABG or PCI.Objective: This study aimed to describe the contemporary evidence PCI for ULMCADCase presentation: A man was admitted to our hospital with crescendo angina accompanied with dyspnea. Electrocardiogram (ECG) showed biphasic t wave on V2-V5 leads. He continued to experience symptoms of ischemia and had increased serial cardiac enzymes. Intra-aortic balloon pump (IABP) support was implemented before performing the PCI. After eight days of hospitalization, he was discharged with stable hemodynamics. Conclusion: PCI has risks and advantages when performed on patients with complex CAD, including ULMCAD. The prognosis for this high-risk patient group can be improved with thorough preparation and effective treatment strategies.
Successful Management of High-Risk Acute Pulmonary Embolism in Patients with Undetected Hepatocellular Carcinoma: A Case Report zunardi, Lutfi hafiz; Kurnianingsih, Novi; Martini, Heny
Heart Science Journal Vol. 4 No. 4 (2023): The Science and Art of Caring for Critically III Patients in Intensive Cardiac
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.hsj.2023.004.04.6

Abstract

AbstractBackground: Acute pulmonary embolism (PE) as the earliest manifestation of hepatocellular carcinoma (also known as HCC) is an extremely uncommon discovery and a very uncommon illness. It is a serious condition that can be life-threatening and has high morbidity and mortality rates. Despite the high prevalence of PE, the diagnosis is still challenging, mainly due to the unpredictability of symptoms and physical signs and the unexplained cause. The stratification of acute pulmonary embolism is important because it determines the right steps in decision-making.Case Illustration: A 45-year-old man presented to the ER at a private hospital with complaints of sudden shortness of breath after taking a bath. His family brought him to the private hospital 30 minutes after the onset. He came with desaturation and shock conditions. He was assessed as having an acute coronary syndrome (ACS). He got loaded with dual antiplatelets and was referred to our hospital. Because the patient's complaint is not angina but sudden shortness of breath accompanied by desaturation, we rule out ACS. We considered the possibility of a pulmonary embolism, so we performed bedside TTE in the ER and found RV dysfunction and McConnell's sign leading to acute PE. We continued with the CT examination and found a thrombus in the pulmonary artery. We assessed patients with high-risk pulmonary embolism and performed thrombolysis with rTPA. The patient's complaints gradually improved. Initially, we suspected unprovoked PE because we did not find a clear trigger, such as malignancy, prolonged bedriddenness, recent surgery, or old age. We accidentally found HCC from the patient's CTPA evaluation, and HBSAG was reactive.Conclusion: Every case of dyspnea that shows up at an emergency room should have acute PE taken into consideration in the differential diagnosis. In patients with suspected PE without obvious risk factors, we can use CT to triple-rule out ACS, Aortic dissection, and pulmonary embolism. Patients treated with thrombolytic therapy show rapid improvement, which may lead to a lower rate of mortality and morbidity.
Echocardiography Features in Patient Rheumatic Mitral Stenosis Dwigustiningrum, Nur Kaputrin; Rahimah, Anna Fuji; Karolina, Wella; Martini, Henny
Heart Science Journal Vol. 5 No. 2 (2024): Challenges in the Management of Congenital Heart and Structural Heart Diseases
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub/hsj.2024.005.02.5

Abstract

Rheumatic mitral stenosis (RMS) is a progressive valvular heart disease that can lead to significant morbidity and mortality, especially in developing countries. Echocardiography plays a crucial role in the diagnosis, assessment, and management of patients with RMS. This study aims to review the utility echocardiography feature in patient RMS. We discuss the key echocardiographic parameters used for assessment and severity of RMS, and associated valvular abnormalities. Additionally, we explore the role of multimodality imaging, such as transesophageal echocardiography in enhancing the diagnostic accuracy and therapeutic decision-making in RMS. A thorough understanding of echocardiographic findings in RMS is essential for clinicians involved in the care of these patients, as it aids in risk stratification, treatment planning, and monitoring of disease progression. Integrating echocardiography is a widely used non-invasive method for comprehensive assessment, monitoring disease progression and evaluating treatment efficacy, ensuring optimal management for patient with RMS.
Increase Cardiovascular Event in Patient with Diabetes Mellitus Undergoing Percutaneous Coronary Intervention Millisani, Hayla Iqda; Prasetya, Indra; Rohman, Mohammad Saifur; Satrijo, Budi
Heart Science Journal Vol. 5 No. 3 (2024): The Science and Art of Revascularization in Acute Coronary Syndrome
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub/hsj.2024.005.03.5

Abstract

Diabetes mellitus (DM) associated with increase major risk factors of cardiovascular disease, such as peripheral arteriopathy, ischemic heart disease, or cerebrovascular accident. The Framingham study showed that patient with DM considerably increase coronary artery disease (CAD), particularly in old patient and women. Prevalence of DM is rising and cardiovascular mortality associated with DM is the main problem in the world. Additionally, there is a higher death rate among DM patients following a myocardial infarction with complications, such as stent thrombosis, instent restenosis, and no reflow phenomenon can worse overall long term prognosis with CAD. This review c onsiders the mechanism for diabetes mellitus in CAD patient, expecially patient with DM can increase risk of major complication in patient CAD undergoing percutaneous coronary intervention (PCI).
Successful Pregnancy in Uncorrected Tetralogy of Fallot with Right Aortic Arch: An Interdisciplinary Team Approach Millisani, Hayla Iqda; Putri, Valerinna Yogibuana Swastika
Heart Science Journal Vol. 5 No. 1 (2024): Inflammation and Cardiovascular Disease
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub/hsj.2024.005.01.8

Abstract

Background: Tetralogy of Fallot (ToF) is the most common cyanotic disorder, with a global prevalence of congenital heart disease nearly reaching 10%. The anomalies observed in individuals with ToF result from the anterior and cephalad displacement of the infundibular (outflow tract) component of the interventricular septum. ToF continues to be a significant contributor to maternal morbidity, mortality, and adverse outcomes in newborns with the condition.Case presentation: An 18-year-old woman in her 28th week of pregnancy was referred to our tertiary referral center, Saiful Anwar Hospital, diagnosed with uncorrected Tetralogy of Fallot (TOF), which had been noticed since she was 2 years old. At that time, her parents refused treatment. She became pregnant unexpectedly and was then directed to RSSA for further management.Conclusion: We present a successful case of pregnancy in a woman who has not undergone surgical repair for ToF. An interdisciplinary pregnancy heart team, including a cardiologist, obstetrician, anesthesiologist, midwives, and neonatologists at our tertiary hospital, developed a care plan based on an individualized assessment of the patient's comorbidities and ToF. The life expectancy of this pregnant woman and her baby is higher with a team approach. The choice of contraception and family planning should be part of the discussion and follow-up from the teenage years, allowing patients with ToF to control their fertility and make informed decisions about having children.

Page 13 of 31 | Total Record : 302

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