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Jurnal Health Sains
Published by Syntax Corporation Indonesia
ISSN : 27236927     EISSN : 27234339     DOI : http://doi.org/10.36418
Core Subject : Health,
Dentistry Health Professions Medicine & Pharmacology Nursing Public Health Veterinary
Jurnal Health Sains adalah jurnal yang diterbitkan sebulan sekali oleh Ridwan Institute. Jurnal Health Sains akan menerbitkan artikel ilmiah dalam lingkup ilmu kesehatan. Artikel yang diterbitkan adalah artikel dari penelitian, studi atau studi ilmiah kritis dan komprehensif tentang isu-isu penting dan terkini atau ulasan buku-buku ilmiah.
Arjuna Subject : Profesi Kesehatan - Bimbingan Kesehatan dan Transkripsi
Articles 764 Documents
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Metode Validasi Analisis Senyawa Kimia Obat dalam Sampel Biologis (Plasma Darah) Fira Aulia Fatan; Gisel Rizuna Qothrunnada; Issabella Elsiana; Kholifatul Ulum; Klaritya Anisya Kurnia; Shafa Qotrunnada Widyatamaka; Shipa Paujiah
Jurnal Health Sains Vol. 3 No. 5 (2022): Jurnal Health Sains
Publisher : Syntax Corporation Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/jhs.v3i5.489

Abstract

Blood plasma is used as a biological sample in determining the levels of drug compounds because the concentration of the drug will bind to its receptors and determine the size of the pharmacological effect of a drug. The purpose of this study was to determine the accuracy of human blood plasma as a sample in several validation methods with different analytes. The research method used is by conducting a literature study in several credible journals with the criteria of the journals of the last 10 years regarding the determination of levels of drug compounds in human blood. The results obtained from five different analytes, namely glibenclamide combination with metformin, formalin, vancomycin, lisinopril and a-mangostin which have been validated using various validation methods, namely SPE-MIP followed by HPLC, UV-VIS spectrophotometer, HPLC-UV, UPLC and TLC densitometry using human blood plasma samples, all meet the validation requirements. So it can be concluded that, human blood plasma used as a sample in the validation test with various different methods and analytes that have been carried out is entirely accurate because all validation test methods meet the requirements
Pengaruh Parenting Education Pada Ibu Terhadap Pengetahuan dan Sikap Ibu Terhadap Balita Tentang Tumbuh Kembang Siti Patimah; Dita Eka Mardiani
Jurnal Health Sains Vol. 3 No. 5 (2022): Jurnal Health Sains
Publisher : Syntax Corporation Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/jhs.v3i5.492

Abstract

The role of the family, especially the mother in raising children, is very important in determining the growth and development of children. In order for parents to be able to carry out their functions properly, parents need to understand the level of child development, assess the growth or development of children, and have a strong motivation to advance the growth and development of children. The results of the study on parenting education show that the skills of parents in carrying out the parenting function are still low Syakrani, 2010 the causes include the absence of parenting programs, low understanding and awareness of parents about the importance and influence of motherhood on children's growth and development, and lack of information about the importance of parenting. child care. Shochib, 2010 explains that the knowledge and attitudes of parents in providing parenting to their children are influenced by the lack of information about ways to achieve a healthy life which can lead to deviations in parenting patterns for children. This study aims to determine the effect of parenting education on mothers of infants under five on the knowledge and attitudes of mothers of infants under five about growth and development. The research method used in this study is a quasi-experimental one-group pretest-post test design. The population of this research is mothers of infants under five in the Cikalang Village, Tasikmalaya City. The subjects of this study were mothers of infants under the age of five in the Cikalang sub-district who were selected using the purposive sampling method. The sample selected as the respondent is determined based on the criteria. Total 70 0 people. univariate analysis to determine the frequency distribution. The results of the data normality test showed that the data distribution was not normal, so the bivariate test used the Wilcoxon test. The results of the study obtained knowledge of mothers of infants under five about growth and development of infants under five before parenting education, the highest level of mother knowledge was in the less category (67.1%), while after attending parenting education the mother's level of knowledge was in the medium category (60%) and the good category (40%). Prior to parenting education, the mother's attitude was mostly in the bad category (64.3%), while after attending parenting education the mother's attitude was mostly in the good category (87.1%). The results of the different test were known as the Asymp.Sig value. (2-tailed) of 0.000 <0.05, which means that H0 is rejected. It can be concluded that there is an influence of parenting education on the knowledge and attitudes of mothers of infants under five about the growth and development of infants under five.
Perbedaan Derajat Keparahan Penyakit Berdasarkan Skor Psoriasis Area and Severity Index (PASI) Terhadap Profil Lipid pada Psoriasis Vulgaris Annisa Marsha Evanti; Fitri Kasmitasari; Muhammad Eko Irawanto
Jurnal Health Sains Vol. 3 No. 5 (2022): Jurnal Health Sains
Publisher : Syntax Corporation Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/jhs.v3i5.494

Abstract

Psoriasis vulgaris is a chronic systemic autoimmune disease that affects skin, joint, nail and other organ with clinical manifestation well-defined erythematous plaques with thick silvery scales. Psoriasis vulgaris is associated with dyslipidemia include elevated level of total cholesterol, LDL and triglyceride serum and decreased HDL serum levels. Psoriasis Area and Severity Index (PASI) is an examination to assess the severity of psoriasis vulgaris and mostly used in clinical practice and research. Purpose: To determine differences in disease severity based on PASI scores on lipid profiles in psoriasis vulgaris patients. Methods: This research is an observational analytic study with cross sectional research design conducted at Dr. Moewardi General Hospital Surakarta from February to March 2022. The total number of subjects was 25 patients with psoriasis vulgaris. All data were analyzed using SPSS version 21 application (IBM Corp. Chicago, USA). Bivariate analysis with parametric independent T test and Mann-Whitney test were used to determine the differences of total cholesterol, LDL, triglyceride and HDL serum level between PASI <10 and PASI ≥10 with p<0,05 considered significant. Results: Patients with PASI <10 had mean value of total cholesterol levels 187,53±26,39, LDL levels 128,24±28,37, triglyceride levels 115,88±61,74 and HDL levels 46,29±11,98 while in patients with PASI ≥10 had value of total cholesterol levels 218,75±34,92 (p=0,020), LDL levels 145,63±35,76 (p=0,201), triglyceride levels 201,88±158,04 (p=0,215) and HDL levels 44,13±11,36 (p=0,672). There is a significant difference between the severity of the disease based on the PASI score on total serum cholesterol levels in psoriasis vulgaris patients. Conclusion: There was a significant difference between PASI score <10 and PASI score ≥10 on total serum cholesterol levels in patients with psoriasis vulgaris.
Asep Wirayasa (2022) CRISPR/CAS9 untuk Modifikasi Gen E7 pada HPV-6 dan HPV-11 sebagai Tatalaksana Kuratif Condyloma Acuminata Asep Wirayasa
Jurnal Health Sains Vol. 3 No. 5 (2022): Jurnal Health Sains
Publisher : Syntax Corporation Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/jhs.v3i5.495

Abstract

Sexually Transmitted Diseases (STDs) or Venereal Diseases (VD) are diseases that are transmitted through sexual intercourse, either vaginal, anal, or oral. HPV infection has a large number of about one million cases every day. One study conducted by WHO stated that 31% of women in Indonesia were exposed to infection from this virus. The HPV that can cause Condyloma Acuminata are HPV-6 and HPV-11. Although pharmacological and preventive therapies such as vaccines have been carried out, the number of sufferers is still increasing and becomes a burden for the country because in general this disease attacks the productive age population, so it is time to take a more sophisticated approach to the curative treatment of this disease. Looking for the latest curative methods that can stop condyloma acuminate permanently in each individual. The research method used is by conducting a literature study through several journal databases such as Pubmed, Cinahl, Google Scholar, and others. Based on several studies, it was found that CRISPR/Cas9 proved to be effective in suppressing the expression of the E7 protein and its sequence, proliferation and at the same time inducing apoptosis through the caspase-3 pathway in the conservative genome-specific proteins E7 HPV-6 and HPV-11. Not only decreasing expression and increasing deletion of the target genome, CRISPR/Cas9 has also been shown to be very efficient in suppressing cell proliferation. Keratin cells that have been exposed to the E7 HPV-6 and HPV-11 genomes will cause uncontrolled cell proliferation. With this method, the treatment of Condyloma Acuminata can be carried out effectively and efficiently so that it does not cause recurrence in the sufferer.
Perawatan Konservatif Rehabilitasi Khusus Terintegrasi yang Komprehensif Untuk Skoliosis Remaja Idiopatik Regina Emmanuela Gusti Pratiwi
Jurnal Health Sains Vol. 3 No. 5 (2022): Jurnal Health Sains
Publisher : Syntax Corporation Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/jhs.v3i5.496

Abstract

Scoliosis is an abnormal lateral curvature of the spine associated with or without rotation of the vertebrae. Scoliosis is not just a cosmetic problem, but it has impact on many aspects of a person’s quality of life. One’s can experience pain, posture, respiratory, psychosocial problems. In This case report we would like to demonstrated an integrated comprehensive, tailor-made rehabilitation treatment for adolescent scoliosis. The patient is a 15-year-old female with complaints of scoliosis and back pain. Her first menarche was when she was 11 years old. No medical Problem was found. She loved to hang out with her friends and family but since her back hump getting worse, she ashamed of herself and sometimes refused to meet them or cover it with thick layer clothes. The pain in scale of 6 has been present for 1 year. She is unhappy with her body alignment and posture. From physical examination we found The Adam forward bend test was positive. From the x-ray before treatment showed the cobb angle was 20. Pelvic tilt (+), Risser sign 3-4, with Scoliosis C Curve. She can easily do her activities without feeling easily tired nor dyspnoea. She was prescribed a tailor-made Boston brace, physical exercise, heating modality, psychosocial intervention. After 12 weeks of therapy and bracing there was an improvement in posture, minimal pain (3-4), and she became more confidence and happy. The spine malalignment and the curvature can compress spinal disks, irritate nerve, strain joints, tighten muscles and it leads to pain. Because of this spine malalignment can affect posture it can leads to a psychosocial problem. Since the cobb angle was 20 degrees, no full maturation found, it is indicated for Brace prescription, to correct posture and prevent progressivity of curve angle. A proper exercise with heating modality can decrease muscle spasm and pain, maintain flexibility and strengthen spine/core muscle. The earlier diagnosis and treatment of an adolescent scoliosis can give so much different; it depends on the maturation and the cobb angle. In this comprehensive treatment needs a support not only from the patient but also from her society.
Aktivitas Antialopesia Sediaan Hairtonic Dari Berbagai Tanaman Arum Hasanah; Dikdik Caesar Barkah; Dinda Aisyah; Nia Yuniarsih
Jurnal Health Sains Vol. 3 No. 6 (2022): Jurnal Health Sains
Publisher : Syntax Corporation Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/jhs.v4i06.508

Abstract

Hair is a part of the body that is often referred to as a crown by every human being given by God. However, problems that can occur in hair if not treated properly can cause one of them is hair loss. Hair loss is a major problem, in appearance. Because having healthy and beautiful hair can increase a person's confidence in appearance. The use of hair tonic today is a must if it is to prevent or repair hair damage, because hair tonic is a liquid cosmetic preparation consisting of chemicals and/or other ingredients that can be used to help repair, strengthen and maintain hair condition. hair tonic is a product for the treatment of hair loss that is safe and does not cause irritation. Various plant extracts are formulated to treat hair loss as an alternative to synthetic hair tonics which can cause side effects. Therefore, this review article aims to inform various kinds of plants that can be used as ingredients for making hair tonic cosmetic preparations. The results of the study of the article show that in various plant parts of plants that have the potential as anti-alopecia for hair tonic preparations are bidara leaves, kukukan leaves, celery leaves, hibiscus flowers and candlenut by showing the effectiveness of hair growth and preventing hair loss within a period of 4-8 days. week.
Aktivitas Antioksidan Serum Gel dari Ekstrak Biji Asam Jawa (Tamarindus indica L) sebagai Penangkal Radikal Bebas dan Pencerah Wajah Farid Ahmad; Siti Ningrum Ratna Ningsih; Nia Yuniarsih
Jurnal Health Sains Vol. 3 No. 6 (2022): Jurnal Health Sains
Publisher : Syntax Corporation Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/jhs.v3i06.509

Abstract

Damage to the facial skin will interfere with the health and appearance of humans so that the facial skin needs to be protected and maintained its health. One of the factors causing damage to facial skin is free radicals. Free radicals can be found in a dirty environment, it is necessary to have an alternative route for free radical scavengers, namely Serum gel from Tamarind Seed Extract (Tamarindus Indica L.) The method used in this study is to use Literature Review Article (LRA). The literature mentions that Tamarind Seeds have a very high antioxidant content. Antioxidant testing on Tamarind Seeds uses the DPPH method (2,2-diphenyl-1-picrylhydrazil) with stable results and has gone through guaranteed clinical test parameters.
The Effect of Education on Quality of Life of Breast Cancer Patients With Family Assistance and Treatment Compliance As A Mediation Variable Rolianna Harianja; Kemala Rita Wahidi; Rina Mutiara
Jurnal Health Sains Vol. 3 No. 6 (2022): Jurnal Health Sains
Publisher : Syntax Corporation Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/jhs.v4i06.510

Abstract

Breast cancer is the most common type of cancer compared to other types of cancer. Breast cancer can have a psychological impact from the early diagnosis. In addition, the side effects of cancer modality therapy can also affect the psychology of patients and families. The purpose of this study was to analyze the effect of providing education on the quality of life of breast cancer patients with family assistance and medication adherence as mediating variables at the "Dharmais" Cancer Hospital. Quality of life is a subjective measure that describes happiness and freedom for an individual and how good or bad a person is. Health education is an important tool for fostering patient empowerment and encouraging their contribution to disease control. Family companion is a form of interpersonal relationship that protects a person from the effects of bad stress. Obedience comes from the root word obedient which means to obey, like to obey orders. Types of correlational research. The population is 1,174 and the sample is 291, using purposive sampling technique and proportional random sampling. Validity test using Pearson product moment. Reliability test using Cronbach alpha. Data collection techniques using questionnaires and statistical analysis of simple and multiple linear regression. The results showed that the average value of providing education, family assistance, medication adherence and quality of life was high. There was an effect of providing education (p=0.000), family assistance (p=0.001) and medication adherence (p=0.000) on the quality of life. The conclusion shows that there is the provision of education, family assistance and medication adherence to the quality of life. So it is suggested that the hospital can pay more attention to improving the quality of life such as doing health promotion.
Potensi Tabir Surya Pada Berbagai Tanaman Herbal Mikha Ayu Lia Ningsih; Mita Lianastuti; Qori Putri Suciyanti; Nia Yuniarsih
Jurnal Health Sains Vol. 3 No. 6 (2022): Jurnal Health Sains
Publisher : Syntax Corporation Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/jhs.v4i06.511

Abstract

The skin is the outermost part of the body that can be exposed to direct sunlight. One of the cosmetics that can be used to protect the skin from the harmful effects of the sun is sunscreen. Herbal plants can be used as active ingredients for making sunscreen, such as Moringa leaves, soursop, basil, blackberries, and onion skin. The purpose of this study was to see the effectiveness of adding plant extracts in the sunscreen formula. The research method was carried out by literature review or literature review in research journal databases from 2012 to 2022. The results showed that there was an effect of sunscreen on plant extracts added to the sunscreen formula, testing both in-vitro using UV-Vis spectrophotometry and in vivo using test animal. Phenolic compounds such as flavonoids and tannins contained in these plants are proven to absorb UV rays.
Faktor-Faktor yang Mempengaruhi Akses Pelayanan Kesehatan di Indonesia Gadisty Bunga Mentari; Susilawati Susilawati
Jurnal Health Sains Vol. 3 No. 6 (2022): Jurnal Health Sains
Publisher : Syntax Corporation Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/jhs.v4i06.512

Abstract

The number of available health facilities raises the question of whether they are able to provide the best medical services and can be accessed by all levels of society. In this case, the government, the Ministry of Health and other stakeholders are required to provide uniform health facilities throughout Indonesia. Therefore, this article provides a review of the factors that affect access to health services in Indonesia. This research method uses a Systematic review research method. Systematic review research is a way in the research process to find the best results from previous research to systematically search the literature and then analyze and conclude data from the results of literature data analysis to answer problems effectively, and significantly. The data that has been collected from the data collection method is then processed and combined to obtain an explanation regarding the factors that affect access to health services in Indonesia. The results of the study based on systematic articles that have been carried out access to health is influenced by a person's gender, distance from home to health care facilities, transportation costs, domicile, community views on health, service quality, income and insight.

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