cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
Ripai Siregar
Contact Email
ripaisiregar1994@gmail.com
Phone
+6282274129993
Journal Mail Official
agngprwr@gmail.com
Editorial Address
Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua Jalan Besar Deli Tua No. 77, Kabupaten Deli Serdang, Sumatera- Utara
Location
Kab. deli serdang,
Sumatera utara
INDONESIA
Jurnal Penelitian Farmasi dan Herbal
Published by INSTITUT KESEHATAN DELI HUSADA DELI TUA
ISSN : -     EISSN : 26547619     DOI : 10.36656/jpfh
Core Subject : Health,
Medicine & Pharmacology
Aims and Scope The Pharmaceutical & Herb Research Journal is a scientific journal published by Institut Kesehatan Deli Husada which publishes research journals in the field of pharmacy. Indonesia has a lot of natural resources that have the potential to have pharmacological effects. This journal is a place for researchers in the field of pharmacy to be able to publish their researches in 2 main areas, namely Pharmacy and Herbs In the Pharmacy area, accepted research articles include: • Pharmaceutical Biology • Pharmaceutical Chemistry • Pharmacology • Pharmaceutical Technology While the Herb area includes • Herb medicinal formulations from natural ingredients The Pharmaceutical & Herb Research Journal can also be a forum for informations and sources of knowledge related to the field of pharmaceutical science and herb medicine in Indonesia.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 193 Documents
 6   7   8   9   10 
FORMULASI DAN UJI AKTIVITAS ANTI BAKTERI SEDIAAN SALEP EKSTRAK ETANOL DAUN SIRIH CINA (peperomia pellucida) TERHADAP BAKTERI Staphylococcus Aureus Rika Puspita Sari
Jurnal Penelitian Farmasi & Herbal Vol 4 No 2 (2022): Jurnal Penelitian Farmasi & Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v4i2.856

Abstract

Chinese betel leaf (Peperomiapellucida) is one among the wild herbaceous plants belonging to the Piperaceae family which is employed as a natural medicine. The study's goal was to determine the antibacterial activity of an ethanol extract of Chinese betel leaf ointment against Staphylococcus aureus, as well as the optimal concentration. The test of the study was administered by the diffusion method using disc paper. The results of the characterization examination of Chinese betel leaf simplicia powder obtained water soluble extract content of 64.58%, ethanol soluble extract content of 24.95%, total ash content of three 3.2%, 5.9 % water of content and 0.28% acid insoluble ash content of and Simplisia contains alkaloids, flavonoids, tannins, and saponins. Staphylococcus aureus obtained a degree of 8% with a diameter of 16.81, the diameter of the inhibition zone of the Chinese betel leaf ethanol extract against. The ethanol extract of Chinese betel leaf exhibits antibacterial action against Staphylococcus aureus, according to the findings of the study. Keywords: Antibacterial activity, Chinese betel leaf Staphylococcus aureus
The FORMULATION AND EVALUATION O FORMULATION AND EVALUATION OF THE PREPARATION OF HAIR TONIC Ethanol Extract of Patchouli Leaves (Pogostemon cablin Benth.) TO OVERCOME HAIR LOSS Bunga Rimta Barus; Linta Meliala
Jurnal Penelitian Farmasi & Herbal Vol 4 No 2 (2022): Jurnal Penelitian Farmasi & Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v4i2.860

Abstract

Nilam leaves contain flavonoids. flavonoids that have activity that can accelerate hair growth and prevent hair loss. The purpose of the study was to make a hair tonic preparation containing patchouli leaf extract and to determine the concentration of the best formula to treat hair loss. Hair tonic is made with nilam leaf extract at concentrations of 5%, 10%, 15%. The ingredients for making Hair Tonic include propylene glycol, propyl paraben, methyl paraben, menthol, sodium metabisulfite, 96% ethanol, Ol. Rosae, Aquades. The method of the study an experimental method with extraction by maceration for 5 days and remaceration for 2 days using 96% ethanol as solvent. Evaluation of Hair Tonic preparations includes homogeneity, pH, organoleptic, viscosity, irritation, preference, and hair growth effectiveness test. The effectiveness test on hair growth in rabbits was carried out on 5 rabbits with 5 treatment groups, namely, positive control group Hair Tonic nature, negative control group, 5% concentration group, 10% concentration group, and 15% concentration group. The analysis of the data on growth testing using One Way Anova. Hair growth data on day 12 were positive control 0.95 mm, negative control 0.03 mm, formula 1 (5%) 0.08 mm, formula 2 (10%) 0.13 mm, formula 3 (15%) 0.83mm. The best formula to treat hair loss is hair tonic with a concentration of 15% nilam leaf ethanol extract. It can be concluded that the greater the concentration of nilam leaf extract given to each treatment, the faster the hair growth.
FORMULASI SEDIAAN BLUSH ON DARI EKSTRAK KUBIS UNGU (Brassica Oleracea L. var. capitates f. rubra) SEBAGAI PEWARNA DALAM BENTUK COMPACT POWDER Nadia Nadia
Jurnal Penelitian Farmasi & Herbal Vol 4 No 2 (2022): Jurnal Penelitian Farmasi & Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v4i2.861

Abstract

Cosmetics have been known to humans since centuries ago. Since the last 40 years, cosmetics has grown rapidly. Quantias and the quality of biological materials for use on the skin are increasing. Blush on is created from attractive colors and of course using coloring agents. Purple cabbage extract is used as a dye in blush on with a concentration of 30% and Isopropyl myristate as a binder with various concentrations of 0.5%, 1.0% and 2.0%. Purple cabbage extract was obtained by 96% ethanol maceration, then filtered and rotary using a rotary evaporator, then evaporated in a water bath with a temperature of 700 C. Blush on is made by pressing. The extract yield obtained was 18.68%. The observations show that preparations with a concentration of Isopropyl myristate 1.0% are better and more preferable because the preparation is not brittle and not too hard. In the pH test, all dosages meet the requirements. In the irritation test, all preparations did not cause irritation reactions to all panelists. Purple cabbage extract can be used as a natural dye in the process of making blush on and the best concentration of Isopropyl myristate is 1.0%.
FORMULASI SEDIAAN MASKER Gel Peel Off EKSTRAK ETANOL DAUN JAMBU BIJI (Psidium Guajava L.) SEBAGAI PEMBERSIH WAJAH Palas Tarigan
Jurnal Penelitian Farmasi & Herbal Vol 4 No 2 (2022): Jurnal Penelitian Farmasi & Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v4i2.862

Abstract

Guava plants contain psiditanin “eugenol” essential oil, tannis, flavonoids, saponins, alkaloids. Compounds that have very good strength come from the class of flavanoids, vitamin C which can be usedas a facial cleanser. This study aims to determine the preparation of peel gel mask of guava leaf extract is effective as a facial cleanser and to find out the peel off gel mask of guava leaf extract can irritate the skin of volunteers. The made with 4 formulation with concentrations of 0%, 10%, 15%, 20%. The testing of the peel off gel mask formulation ethanol extract on cleanliness was carried out with the analysis of the ms. Excel bar diagram. The results showed that (psidium guajava L) contain flavonoid, alkaloids, tannins and saponins. The results of the characteristics of the simplicia powder were 5,42% water content 9,56% total ash content 0,34% acid insoluble ash, ethanol soluble extract 64,295. The results of the peel off gel mask formulation test with a cleanliness test on the panelists facial skin concentration of 15% included in the category can clean the panelist’s facial skin.Guava leaf ethanol extract has a facial cleansing activitywith a score of 3
UJI AKTIVITAS EKSTRAK BUAH ARA (Ficus carica Linn) TERHADAP TIKUS YANG DI INDUKSI ALOKSAN Atika Patni Suri
Jurnal Penelitian Farmasi & Herbal Vol 4 No 2 (2022): Jurnal Penelitian Farmasi & Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v4i2.865

Abstract

Diabetes is a disease in which the blood sugar level rises above the normal level. When blood sugar levels are regulated by the hormone insulin produced by the pancreas. The fig fruit (Ficus carica Linn) is a plant that is thought to be used as an herbal remedy in the management of diabetes. Contains flavonoids which are thought to have potential as antidiabetic. Flavonoid mechanism in reducing blood glucose levels is to reduce glucose absorption and increase insulin secretion. Flavonoids are phenol compounds that have several pharmacological activities. Objective knowing antidiabetic activity of fig extract (Ficus carica Linn) against mice induced by alloxan. The process used is a 70% ethanol solvent immersion process. This study method is designed before and after the control group. Fifteen rats were divided into 5 treatment groups. 1 (negative control) received the CMC Na 1% group, 2 (positive control) received glibenclamide 0.09 mg / kgBB, 3, 4 and 5 received 9 mg / kgBB, 18 mg / kgBB, and 36 mg / kg. The fig extract was administered at a dose of kgBB. Previously, rats were given alloxan 125 mg / kg BB intraperitoneally for 3 days and mice with a blood glucose level of ± 200 mg / dL were used in this study. The results of this study showed that glibenclamide 0,09 mg/kgBB and fig extract dose 36 mg/kgBB could reduce the best glucose levels for seven days. Conclusion the best glibenclamid as antidiabetic in male white rats induced by alloxan and fig extract at a dose of 36 mg/kgBB 1,5% concentration is good as antidiabetic mellitus in male white mice induced by alloxan.
PEMBUATAN MIKROKRISTALIN SELULOSA (MCC) dari BATANG PISANG MAS (Musa acuminata colla) dengan AVICEL PH 102 SEBAGAI PEMBANDING TAHUN 2019 Erdiwan Erdiwan
Jurnal Penelitian Farmasi & Herbal Vol 4 No 2 (2022): Jurnal Penelitian Farmasi & Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v4i2.866

Abstract

Commercial cellulose microcrystalline known as Avicel PH 102, which is a tablet filling material Avicel PH 102 which is expensive and uses a lot of it, it is necessary to look for other alternative sources of producing microcrystalline cellulose. The Waste of banana stem contains water content of 80-90%, cellulose 63-64%, hemicellulose 20%, and lignin 5% and contains 11-12% other constituens so that it can be the basic material for making MCC. This study aimed to isolate α-cellulose from banana mas stems and characterize microcrystalline cellulose with Avicel PH 102. The method of this study was an experimental. Microcrystalline banana stem cellulose is obtained by heating banana stem powder with 4% NaOH which serves to dissolve lignin, then bleached with 2.5% NaOCl, 17.5% NaOH heated to dissolve β-cellulose and γ-cellulose, and heated with HCL 2 N . The results are hydrolyzed with α-cellulose and then hydrolyzed with 2.5N HCl to give microcrystalline cellulose, which is characterized and compared to Avicel PH102. The result of characterization of banana mas stem microcrystalline cellulose and Avicel PH 102 which were obtained respectively is organoleptic tests of coarse powder, white, doesn’t have any smells; pH 6.6 and 6.5; solubility of substances in water 0.023 and 0.023%; total ash content are 0.17 and 0.12%; decrease of drying 5.47 and 5.28%; real density 0.337 and 0.404 g / cm3; true type weight 1.43 and 1.43 g / cm3; incompressible density 0.478 and 0.480 g / cm3; compressibility index 41.77 and 18.85%; Hausner index 1.41 and 1.18; porosity; 76.43 and 93.640%. Based on the results of the study concluded that microcrystalline cellulose can be made from banana mas stems and has the same characteristics as Avicel PH 102.
Pengaruh Pemberian Omeprazole Terhadap Profil Farmakokinetika Piroxicam Dengan Metode Kromatografi Cair Kinerja Tinggi (KCKT) Dasma Arihan Nauli Sipayung
Jurnal Penelitian Farmasi & Herbal Vol 4 No 2 (2022): Jurnal Penelitian Farmasi & Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v4i2.867

Abstract

Piroxicam is an anti-inflammatory drug belonging to the NSAID group and is also used as an analgesic and anti-rheumatic drug. Its use is often combined with stomach medicines, as the side effects of piroxicam can irritate the stomach. One of them is omeprazole. Since piroxicam and omeprazole act on the same enzyme, CYP450, they can affect the pharmacokinetic profile, especially at the metabolic stage and excretion of piroxicam. The purpose of this study was to determine the effect of omeprazole on the pharmacokinetic profile of piroxicam especially in the metabolic phase and excretion. The method used in this study was an experimental method using three male rabbits. These rabbits are divided into three groups. The first treatment group was giving pyroxicam solution 0.653 mg / kg body weight, the second treatment group gave piroxicam 0.653 mg / kg body weight that one hour before was given omeprazole 1.2 mg / kg body weight and the third group treated with piroxicam 0.7 mg / kg body weight at the same time with omeprazole 1,4 mg / kg body weight. Plasma levels of the drug piroxicam are measured using a high performance liquid chromatography (HPLC) tool. The verification method is executed. This is the determination of LOD and LOQ values, accuracy and accuracy testing. The result of data analysis using t-table. The results showed that there was an increase or difference in pharmacokinetic parameter values ​​during the absorption phase, but no significant effect was shown for each group. Pharmacokinetic parameter values ​​for metabolic stages and excretion were reduced and no significant difference was shown between the groups. Simultaneous administration of omeprazole and piroxicam and administration of piroxicam 1 hour before omeprazole may inhibit piroxicam-metabolizing enzymes and thus affect pharmacokinetic parameters and excretion during absorption, but are not significant.
PENGUJIAN EFEKTIVITAS PENYEMBUHAN LUKA BAKAR GEL EKSTRAK ETANOL DAUN TEMBAKAU (Nicotiana tabacum L.) PADA TIKUS Mona Hutagalung
Jurnal Penelitian Farmasi & Herbal Vol 4 No 2 (2022): Jurnal Penelitian Farmasi & Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v4i2.868

Abstract

Tobacco leaves (Nicotiana tabacum L.) have secondary metabolites namely alkaloids as antibacterial, flavonoids and steroids / terpenoids as antimicrobials and adstringers which play a role in wound shrinkage, efficacious saponins stimulate collagen formation. This study aims to determine the effectiveness of tobacco leaf gel ethanol extract in the healing of burns. Tobacco leaf extract was prepared using a 96% ethanol immersion process. This study of tobacco leaf extract is prescribed in the form of gels at 5%, 10%, and 15% concentrations. There were five groups in this study. The first group (positive control), the second group (negative control), and the third group are tobacco leaf ethanol extract gels 5%, 10%, and 15%. In this study, 15 rats with burns on the backs of mice coated with the test preparation will be measured and photographed once daily. This is done until the wound is 0 cm in diameter or covered with new tissue. The data results of the mean wound healing rate data were statistically tested using the SPSS program. We analyzed the data using Oneway, ANOVA, TukeysB, and LSD to see the actual differences between the processes. The data results of the analysis on day 16 showed that the 15% tobacco leaf ethanol extract had a wound healing effect that was not significantly different from the positive control (Bioplasenton) (p> 0.05). cure burns that are comparable to comparable drugs (Bioplasenton). The conclusion of this study is that the most effective gel concentration is 15% with the day of recovery on the 16th day.
Formulasi Dan Evaluasi Sediaan Krim Pewarna Rambut Dari Ekstrak Etanol Umbi Bit (Beta vulgaris L.) Sarah Damayanti
Jurnal Penelitian Farmasi & Herbal Vol 4 No 2 (2022): Jurnal Penelitian Farmasi & Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v4i2.869

Abstract

The use of natural hair dyes is a solution to the problem of synthetic hair dyes. one of the plants such as beetroot contains a lot of secondary metabolites, one of which is flavonoids which can provide specific dyes. The natural color found in beetroot can be used as a natural dye in cosmetics. To find out at what concentration the beetroot produces the most optimal quality physical color of the hair dye preparation. This research method was carried out including making beetroot (Beta vulgaris L.) ethanol extract by maceration for 5 days with 95% ethanol solvent and continued remeseration with the same solvent. The extract formula used was 10%, 15%, and 20% physical evaluation carried out included organoleptic test, irritation test, pH test, homogeneity test, stability test for washing, stability test for sunlight. As a result of inspection of the three hair dye cream formulations, the formulations met the requirements of the test formulations. The results of the hair tack test showed that it gave a good color at a density of 20% time. In the color stability test of the wash after 15 shampoo washes, all three formulations have a fixed color up to 9 washes. Also, in terms of color stability to sunlight, after exposure to direct sunlight, the color appears to change slightly, making the hair darker than before. The result of the concentration of beetroot ethanol extract that gives the best color is a concentration of 20%.
FORMULASI DAN UJI AKTIVITAS ANTIBAKTERI SEDIAAN LOTION EKSTRAK ETANOL DAUN DUKU (Lansium domesticum Corr.) TERHADAP BAKTERI Staphylococcus Aureus PADA PENYEMBUHAN PENYAKIT KULIT BERNANAH TAHUN 2022 sulasmi sulasmi
Jurnal Penelitian Farmasi & Herbal Vol 4 No 2 (2022): Jurnal Penelitian Farmasi & Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v4i2.870

Abstract

Duku leaves (Lansium domesticum Corr.) can be used as an alternative treatment for skin-related diseases such as boils caused by Stapylococcus aureus. Duku leaves contain flavonoids, saponins and triterpenoids that are able to provide antibacterial effects. This study aims to formulate duku leaf extract intopreparations lotion antibacterialagainst Stapylococcus aureus. The study was conducted experimentally, the sample was extracted by maceration method, then the extract was formulated intopreparations lotion with concentrations of 4%, 8% and 12%, of the three concentrations compared with positive control (caladin), negative control (basis lotion), then evaluation was carried out in the form organoleptic test, homogeneity test, dispersion test, pH test, irritation test and hedonic test for each formulation. After the evaluation data was obtained, an antibacterial test was carried out for each formulation. Then proceed with statistical analysis method One Way Anova. The results obtained at a concentration of 4% have the best formula in terms of organoleptic and hedonic (attractive color), thick shape, smells of perfume). In terms of pH it has a pH of 7.0; spreadability (6.27 cm ± 0.4); There is no irritation in this formulation. Based on statistical analysis, the sig Anova value of P < 0.05 (0.000) showed that there was a difference between each formulation in the concentration variation when compared to the positive control. Based on the antibacterial test the formulation concentration of 12% had the best antibacterial properties, namely 16.82 mm ± 4.00 compared to other formulations and the positive control had the best antibacterial properties, namely 17.32 mm ± 1.58. Based on statistical analysis, sig P value < 0.05 (0.000) which means that there are differences in each antibacterial formulation when compared with positive controls. The results showed that in terms of formulation, lotion with a concentration of 4% was the best formulation compared to other formulas. Based on antibacterial lotion concentration of 12% has the best antibacterial properties compared to other formulas.

Page 8 of 20 | Total Record : 193

 6   7   8   9   10 

Filter by Year

2018 2025


Reset
Filter By Issues
All Issue Vol 8 No 1 (2025): Jurnal Penelitian Farmasi dan Herbal Vol 7 No 2 (2025): Jurnal Penelitian Farmasi Dan Herbal Vol 7 No 1 (2024): Jurnal Penelitian Farmasi & Herbal Vol 6 No 2 (2024): Jurnal Penelitian Farmasi & Herbal Vol 6 No 1 (2023): JURNAL PENELITIAN FARMASI & HERBAL Vol 5 No 2 (2023): JURNAL PENELITIAN FARMASI & HERBAL Vol 5 No 1 (2022): JURNAL PENELITIAN FARMASI & HERBAL Vol 4 No 2 (2022): Jurnal Penelitian Farmasi & Herbal Vol 4 No 1 (2021): Jurnal Penelitian Farmasi & Herbal Vol 3 No 2 (2021): Jurnal Penelitian Farmasi & Herbal Vol 3 No 1 (2020): Jurnal Penelitian Farmasi & Herbal Vol 2 No 2 (2020): Jurnal Penelitian Farmasi & Herbal Vol 2 No 1 (2019): Jurnal Penelitian Farmasi & Herbal Vol 1 No 2 (2019): Jurnal Penelitian Farmasi & Herbal Vol 1 No 1 (2018): Jurnal Penelitian Farmasi & Herbal More Issue