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Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua Jalan Besar Deli Tua No. 77, Kabupaten Deli Serdang, Sumatera- Utara
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INDONESIA
Jurnal Penelitian Farmasi dan Herbal
Published by INSTITUT KESEHATAN DELI HUSADA DELI TUA
ISSN : -     EISSN : 26547619     DOI : 10.36656/jpfh
Core Subject : Health,
Medicine & Pharmacology
Aims and Scope The Pharmaceutical & Herb Research Journal is a scientific journal published by Institut Kesehatan Deli Husada which publishes research journals in the field of pharmacy. Indonesia has a lot of natural resources that have the potential to have pharmacological effects. This journal is a place for researchers in the field of pharmacy to be able to publish their researches in 2 main areas, namely Pharmacy and Herbs In the Pharmacy area, accepted research articles include: • Pharmaceutical Biology • Pharmaceutical Chemistry • Pharmacology • Pharmaceutical Technology While the Herb area includes • Herb medicinal formulations from natural ingredients The Pharmaceutical & Herb Research Journal can also be a forum for informations and sources of knowledge related to the field of pharmaceutical science and herb medicine in Indonesia.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 193 Documents
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EVALUASI UJI EFEKTIVITAS EKSTRAK KAYU MANIS (Cinnamomum burmanni) SEBAGAI LARVASIDA TERHADAP KEMATIAN JENTIK NYAMUK (Aedes aegypti) Ike Widiya R
Jurnal Penelitian Farmasi & Herbal Vol 5 No 1 (2022): JURNAL PENELITIAN FARMASI & HERBAL
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v5i1.1001

Abstract

Alternative larvicides against Aedes aegypti larvae and safe for the environment, one of which is cinnamon oil which has been shown to have a larvicidal effect on larvae. Cinnamon contains flavonoid compounds which are strongly suspected to have a larvicidal effect. It can be said that this research is to determine the effectiveness of extracts from cinnamon as a larvicide against the death of Aedes aegypti mosquito larvae. And for the extraction method used in this study using the maceration method. For a concentration of 2% it can kill a total of 32 (53%) larvae, and for a concentration of 4% it can kill 43 (72%) total lava, and a concentration of 6% can kill 53 (88%) larvae, and for a positive control, namely abate (temephos). ) has the best larvicidal effect with an average % larval mortality of 100% within 1 hour. Cinnamon extract test treatments with a concentration of 2% (2ml/100ml) experienced larval death 32 (43%), and for a concentration of 4% (4ml/100ml) experienced larvae mortality 43 (53%). and for a concentration of 6%, 53 (88%) larvae died. And for temephos, it was able to kill a total of all larvae, while for negative control it did not die. The most effective concentration of cinnamon extract in killing larvae was 6%, the higher the concentration, the higher the larval mortality value.
ANALISIS TINGKAT KEPUASAN PASIEN ANALISIS TINGKAT KEPUASAN PASIEN RAWAT JALAN PESERTA BPJS KESEHATAN TERHADAP PELAYANAN FARMASI DI INSTALASI RSU SEMBIRING Anggun Syafitri; Bintang Lubis; Jhan Saberlan Purba; Sri Sudewi Pratiwi Sitio; Efrata Sembiring; Yunita Syaputri Damanik
Jurnal Penelitian Farmasi & Herbal Vol 5 No 1 (2022): JURNAL PENELITIAN FARMASI & HERBAL
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v5i1.1020

Abstract

Quality health services are health services that can satisfy every user of health services in accordance with the level of satisfaction. Satisfaction will occur if the expectations of the patient can be met by the services provided by the hospital so that it needs to be considered continuously the satisfaction and expectations of the patient. The purpose of this study was to determine the level of satisfaction of outpatients of BPJS Kesehatan participants with pharmaceutical services at the outpatient Pharmacy Installation at RSU Sembiring. The design of this study used descriptive survey research. The population in this study was 1400 patients, and the sample was 93 patients using the Slovin formula. Data collected through primary and secondary data and using univariant and bivariant analysis with the help of the SPSS computer program. The results of the chi square test obtained variables related to the satisfaction of outpatients at the general hospital, namely: Physical evidence (p value = 0.002), Reliability (p value = 0.000, Responsiveness (p value = 0.002), Guarantee (p value = 0.004), and Empathy (p value = 0.000). It is recommended to the Outpatient Pharmacy of Sembiring General Hospital to maintain a good quality of service and continue to improve the quality of service to patients.
STANDARISASI SIMPLISIA DAUN KELOR (Moringa oleifera L.) DARI DESA LUWUNG SIDOARJO DENGAN MENGGUNAKAN PENGERINGAN FOOD DEHYDRATOR MELLA NUR AZIZAH; ARISTA WAHYU NINGSIH; BUTET SINAGA
Jurnal Penelitian Farmasi & Herbal Vol 5 No 1 (2022): JURNAL PENELITIAN FARMASI & HERBAL
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v5i1.1034

Abstract

One of the vegetation that may be used each as meals and medication is the Moringa plant (Moringa oleifera L.). Empirically, Moringa leaves have many advantages and had been proven to be powerful in treating numerous diseases, consisting of diabetes, hepatitis, heart ailment and excessive cholesterol. The chemical parts contained on this plant are terpenoids, tannins, steroids, polyphenols, and alkaloids. This look at aims to pick out medicinal uncooked substances the use of the meals dehydrator drying method whilst on the equal time making sure the drug raw materials, so that the standardization can be accounted for for its quality. Standardization is done by setting specific and non-specific parameters. This study uses descriptive qualitative and quantitative analysis methods. The sample of this research was taken from Luwung village, Sidoarjo regency. The results of standardization for specific parameters showed the determination of the flavonoid content of 16,08±3,62 mgQE/g, the TLC test showed stains in the form of yellow-green fluorescence under UV light at 366 nm, the water-soluble extract test yielded 7.8%, and the water-soluble extract test yielded 7.8%. ethanol yielded 13.58%. The results for non-specific parameters showed that drying shrinkage was 4.2%, water content was 1.80%, and ash content was 1.4%. The results of the microbial contamination test were 3.9x colonies/ml while the total mold/yeast contamination was 3.1x colonies/ml. Based at the results of studies that has been carried out, Moringa leaf simplicia from Luwung village has met the requirements of specific and non-specific parameters, so that the simplicia may be used as raw material for medication.
ANALISIS CEMARAN LOGAM BERAT TIMBAL (Pb) PADA MAKANAN DAN MINUMAN : STUDI LITERATUR Audi Ichsani Aribowo; Bunga Nur Annisa; Nena Vauziah Sary; Lina Nurfadhila; Marsah Rahmawati Utami
Jurnal Penelitian Farmasi & Herbal Vol 5 No 1 (2022): JURNAL PENELITIAN FARMASI & HERBAL
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v5i1.1038

Abstract

Heavy metals are defined as the transition elements that have a high atomic mass, are toxic, and cannot be broken down by living organisms. Metal Lead (Pb) is one of the heavy metals which are widely distributed in the environment. Heavy metal lead is one of the causes of serious health problems because it can cause disturbances to the human body. Therefore, the aim of this literature review is to present an illustration and up-to-date data on the analytical methods used for food and beverages contaminated with lead heavy metal (Pb). The methodology of this research is a literature review study from several databases such as Science Direct, Pubmed, and Google Scholar with a limitation of publication in the last 10 years. The results of a literature review from the analysis of Pb metal contamination in food and beverages, there are several techniques that can be utilized to analyze and various factors that cause the amount of lead (Pb) levels such as the atomic absorption spectrophotometer (AAS) method.
GAMBARAN PENGETAHUAN DAN UPAYA SWAMEDIKASI MAHASISWA FAKULTAS KESEHATAN MASYARAKAT UIN SUMATERA UTARA MEDAN Wahyudi Wahyudi
Jurnal Penelitian Farmasi & Herbal Vol 5 No 1 (2022): JURNAL PENELITIAN FARMASI & HERBAL
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v5i1.1057

Abstract

Swamedikasi merupakan upaya diri untuk menggunakan atau memperoleh obat tanpa diagnosis, resep, pengawasan ataupun konsultasi dengan dokter untuk mengobati suatu penyakit ringan tertentu. Penelitian ini bertujuan Untuk mendeskripsikan pengetahuan dan upaya mahasiswa Fakultas Kesehatan Masyarakat UIN Sumatera Utara Medan. Penelitian ini merupakan penelitian kuantitatif deskriptif menggunakan menggunakan metode survey. Pengumpulan data dilakukan dengan kuesioner via google form yang selanjutnya dianalisis untuk dapat mendeskripsikan hasil penelitian. Hasil penelitian menunjukkan bahwa tingkat pengetahuan swamedikasi mahasiswa FKM UIN Sumatera Utara termasuk kategori kurang baik dimana 52,7% mahasiswa belum familiar dengan istilah swamedikasi dan hanya 25,9% yang mengetahui bahwa antibiotik harus dibeli dengan resep dokter. Upaya swamedikasi mahasiswa termasuk kategori baik karena 62,5% mahasiswa melakukan upaya swamedikasi jika mengalami sakit ringan, 43,8% mengetahui aturan pakai obat dari apoteker/asisten apoteker dan 52,7% mengetahuinya dari kemasan obat. Penelitian ini juga menunjukkan bahwa mahasiswa telah melakukan persiapan swamedikasi dengan cara menyimpan obat yang akan digunakan saat mereka sakit. Kesimpulan dari penelitian ini adalah tingkat pengetahuan swamedikasi mahasiswa FKM UIN Sumatera Utara termasuk kategori kurang baik (36,6%) dan upaya swamedikasi termasuk kategori baik (80,36%). Obat yang paling banyak disimpan sebagai persiapan swamedikasi adalah obat penurun demam (82,1%).
PENYALAHGUNAAN AMFETAMIN DAN DAMPAK PENGGUNA TERHADAP KESEHATAN DAN SOSIAL : LITERATURE REVIEW Bunga Nur Annisa; Indah Laily Hilmi; Salman Salman
Jurnal Penelitian Farmasi & Herbal Vol 5 No 1 (2022): JURNAL PENELITIAN FARMASI & HERBAL
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v5i1.1060

Abstract

Drug abuse is defined as the use of one or more types of drugs without medical regulations or not according to indications so that it has various side effects, including physical, psychological, and social dysfunction. One of the drugs that are often used by the public is amphetamine because amphetamine causes euphoria and a sense of calm (psychotropic group). Hence, the purpose of this literature review is to provide an overview and the most recent information regarding the effects of amphetamine use. The method for this literature analysis is by evaluating references from Science Direct, PubMed, and Google Scholar, with a publication restriction of the previous 10 years. Based on the relevant literature, amphetamine misuse has diverse impacts on its users. Drug abuse has psychological and physical effects on adolescents (students) to adults and affects a person's social interactions.
A ntihypercholesterolemia UJI EFEKTIVITAS ANTIHIPERKOLESTEROLEMIA EKSTRAK DAUN KOPI ARABIKA (Coffea arabica L.) PADA TIKUS PUTIH JANTAN (Rattus norvegicus) YANG DIINDUKSI DIET TINGGI LEMAK Linta Meliala
Jurnal Penelitian Farmasi & Herbal Vol 5 No 1 (2022): JURNAL PENELITIAN FARMASI & HERBAL
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v5i1.1063

Abstract

Hypercholesterolemia is a condition that cholesterol in the blood increases beyond the normal which is one of the risk factors for cardiovascular disease. Arabica coffee leaves are part of the arabica coffee plant which contains flavonoid, saponin, mangiferin, chlorogenic acid which are thought to reduce cholesterol levels in the blood. This study aims to determine the antihypercholesterolemia effectiveness of arabica coffee leaves ethanol extract (ACLEE) in male rats induced by a high-fat diet. The test of antihypercholesterolemia effectiveness used male rats induced by a high-fat diet as test animals. The study used 25 rats and divided into 5 groups : negative control (CMC-Na 0.5%), positive control (simvastatin 0.9 mg/kgBW), ACLEE 200 mg/kgBW, ACLEE 300 mg/kgBW and ACLEE 400 mg/kgBW. Total cholesterol were measured by the CHOD-PAP method. The data obtained were analyzed statistically used one way Anova. The results of statistical analysis showed that there was a significant difference between negative control with positive control, ACLEE 200, 300 and 400 mg/kgBW (p-value<0.05). The decrease in total cholesterol levels increased in line with the increase in the dose of arabica coffee leaves ethanol extract. The most effective of ACLEE as antihypercholesterolemia was ACLEE 400 mg/kgBW. There was no significant difference between positive control and ACLEE 400 mg/kgBW (p.>0.05). Based on the results of statistical analysis, it can be concluded that the arabica coffee leaves ethanol extract has antihypercholesterolemic effect in rats.
FORMULASI SEDIAAN CREAM DAN UJI AKTIVITAS ANTIBAKTERI PADA EKSTRAK ETANOL KOMBINASI KULIT PISANG (Musa paradisiaca) DAN KULIT NANAS (Ananas comosus) TERHADAP BAKTERI PENYEBAB JERAWAT Propionibacterium acnes Pintata Sembiring
Jurnal Penelitian Farmasi & Herbal Vol 5 No 1 (2022): JURNAL PENELITIAN FARMASI & HERBAL
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v5i1.1065

Abstract

Background: Acne vulgaris is a chronic inflammatory skin disease with a complex pathogenesis, involving sebaceous glands, follicular hyperkeratosis, bacterial overgrowth, immune and inflammatory responses. Objective: This formulate the ethanol extract of banana peel and pineapple peel into cream preparations and to test the effective antibacterial activity of the combination of banana peel and pineapple peel ethanol extract cream against Propionibacterium acnes. Methods: This research was conducted experimentally with maceration extraction using 70% ethanol as solvent. Acne cream is made with a concentration ratio between (Banana peel: Pineapple peel) namely F1 (Cream Base), F2 (5%:15%), F3 (7.5%:12.5%), F4 (10%:10% ), F5 (12.5%:7.5%), F6 (15%;5%), F7 (20%:0%) and F8 (0%;20%). Then, the physical stability test was carried out in the form of organoleptic test, viscosity test, pH test, homogeneity test, spreadability test and cream type test. Followed by testing the bacteria Propionibacterium acnes in Na media. Results: The antibacterial activity test on F3 showed that the diameter of 20.18 mm was relatively larger than F1 of 0mm, F2 of 18.63 mm, F4 of 18.38 mm, F5 of 16.48 mm, F6 of 18.28 mm, F7 of 13.91 mm and The F8 is 16.11 mm. Conclusion: Cream preparations from formula 1 to formula 8 the cream stability organoleptic test, viscosity test, pH test, homogeneity test, test spreadability and cream type test. The cream preparation in formula 3 has the widest diameter for antibacterial activity compared to other formulas.
STUDI FARMAKOVIGILANS PADA OBAT HERBAL Cantika Nurul Sa'adah
Jurnal Penelitian Farmasi & Herbal Vol 5 No 1 (2022): JURNAL PENELITIAN FARMASI & HERBAL
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v5i1.1067

Abstract

There is a trend of "back to nature" which has become the lifestyle of today's society, so that people return to using various natural ingredients in medicine. A drug side effect is any adverse and unwanted response to a drug that occurs at doses normally used in humans for the treatment of disease, diagnosis, prevention, or modification of physiological function. Pharmacovigilance is carried out with the aim of monitoring drug safety by detecting an increase in the incidence of Advers Drugs Reaction (ADR). This review was conducted to see an overview of the initial data/reports on the relationship between the use of herbal medicines and the incidence of ADR. As a result, it is known that the percentage of ADR events in various places is 19%, 12%, 13.36% and 10-15% with possible and probable categories. The types of herbal medicines used are white turmeric, fitsea, garcia, ginger water, turmeric, herbalife, niran, calcusol, vegeta, tensigard, diapet, herbal vegeta, diabetes herbs, hypertension herbs, cholesterol herbs, kidney stone herbs, anti-inflammatory analgesic herbs, herbal medicine for asthma and herbal medicine for diarrhea.
ANALISIS KADAR ASAM ASETAT HASIL FERMENTASI ECO-ENZYME DARI KULIT JERUK BALI (Citrus maxima Merr.) DAN POTENSINYA SEBAGAI ANTIOKSIDAN DENGAN METODE ALKALIMETRI DAN DPPH bungamri sembiring
Jurnal Penelitian Farmasi & Herbal Vol 5 No 1 (2022): JURNAL PENELITIAN FARMASI & HERBAL
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v5i1.1069

Abstract

The garbage problem is a very important problem because it has the potential to damage the balance of the environmental ecosystem. Many studies have been carried out on the content of active compounds in grapefruit peel, but there are differences in sampling locations, types of solvents for extraction, differences in treatment and testing. In the discovery of Eco-enzyme fermentation solution product, Dr. Rosukon Poompanvong to help local farmers to obtain better yields while being friendly to the environment. Eco-Enzyme is a popular fermented fruit peel organic waste which has been developed because it is very practical, economical, and environmentally friendly. Utilization of fruit peels into Eco-Enzyme is an evolution of science in the health sector. This study aims to determine the Eco-Enzyme fermentation process from pomelo peel and Eco-Enzyme acetic acid levels and their potential as antioxidants with experimental research using Eco-Enzyme sample solution with FeCl3 solution as a qualitative test indicator for Eco-Enzyme samples. Quantitative test using 1-2 drops of Eco-Enzyme sample solution 0,1 M NaOH standard solution and phenolphthalein indicator solution in alkalimetric titration and DPPH method with DPPH solution using UV-Vis spectrophotometer. From the results of qualitative research, the results of Eco-Enzyme fermentation are in the form of a light brown solution, have a brick red precipitate, and there is a brick red precipitate. The results of quantitative research on alkalimetric titration of Eco-Enzyme fermentation, there is an acetic acid level of 7.5% per one gram of pomelo peel, and the DPPH method on the fermented Eco-Enyme solution with an IC50 value of 9.418075752 ppm, which means it has very strong antioxidant potential. Eco-enzyme sample solution has acetic acid level of 7,5% per one gram of pomelo peel and has very strong antioxidant potential

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