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Linta Meliala
Institut Kesehatan Deli Husada
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UJI EFEK ANTIDIARE EKSTRAK RIMPANG KUNYIT (Curcuma domestica val.) PADA MENCIT JANTAN Linta Meliala; Winda Sari; Palas Tarigan
Jurnal Penelitian Farmasi & Herbal Vol 2 No 2 (2020): Jurnal Penelitian Farmasi & Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v2i2.208

Abstract

Objectives : The purpose of this study to determine the effect and dose of effective use of rhizome extract of turmeric as antidiarrhea in male mice induced castor oil and the use of rhizome extract of turmeric equivalent to Loperamid HCl. Method : This research method is carried out experimentally with the research stages of sample preparation, sample characterization, simplicia screening, preparation of extracts, preparation of animal experiments and testing of antidiarrheal effects in experimental animals. Results : The results showed that the results of phytochemical screening of simplicia powder and turmeric rhizome extract contained flavonoids and tannins. SPSS statistical test results (statistical package for the social science) continued with defference test of Duncan average, the duration of the occurrence of diarrhea showed that the control group of Loperamid HCl dose 1 mg/kg bw gave significant effect on turmeric rhizome extract at doses of 40 mg/ kg bw and doses 80 mg/kg bw. The shorter the time of diarrhea, the stronger the antidiarrheal effect. Conclusion : Turmeric rhizome extract dose 20 mg/kgbw showed that dose 20 mg/kgbw has antidiarrhea effect more than lower than Loperamid HCl dose 1 mg/kg bw. Turmeric rhizome extract dose 40 mg/kg bb has same effect with Loperamid HCl dose 1 mg/kgbb. And turmeric rhizome extract dose 80 mg/kgbb has effect more potencial that Loperamid HCl dose 1mg/kg bw. There is a relationship between the size of the dose with the antidiarrheal effect that occurs.
UJI EFEKTIVITAS SALEP EKSTRAK ETANOL RIMPANG JERINGAU (Acorus calamus L.) TERHADAP PENYEMBUHAN LUKA SAYAT Linta Meliala
Jurnal Penelitian Farmasi & Herbal Vol 3 No 1 (2020): Jurnal Penelitian Farmasi & Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v3i1.310

Abstract

Introduction: Jeringau rhizome plants are one of the traditional plants which are used as antibacterial. Method: The extraction process was carried out by maceration using 80% ethanol. The effectiveness of jeringau rhizome testing was divided into 5 treatments, the positive group used betadine ointment, negative control using an ointment base, and the test group used ethanol extract ointment with 5%, 10% and 15% concentration. Cut wounds given to the rabbit's back with a 2 cm long wound and 2 mm deep, the ointment applied twice a day for 13 days and measured using a ruler or calipers. Result: The results show that Jeringau rhizome contains flavonoid, tannin, saponin, and alkaloid metabolites which can be used as wound heal wound healers. This study aims to determine its effectiveness as a wound healer wound. Conclusions: indicate that the ointment extract jeringau rhizome at a concentration of 15% is the most effective control as a wound healer but the ointment extract of jeringau rhizome ethanol extract is less effective when compared to betadine ointment as a wound healer in rabbits. .
PERBANDINGAN SEDIAAN SIRUP ANTIDIARE EKSTRAK DAUN SAWO (Manilkara zapota L.) DENGAN SEDIAAN SIRUP ANTIDIARE DI PASARAN TERHADAP MENCIT PUTIH (Mus musculus L.) Linta Meliala; Anggun Syafitri
Jurnal Penelitian Farmasi & Herbal Vol 4 No 1 (2021): Jurnal Penelitian Farmasi & Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v4i1.746

Abstract

Background: the Sapodilla leaves (Manilkara zapota L.) contain chemical compounds of tannins and flavonoids which have antidiarrheal activity. Tannins are astringent and flavonoids inhibit intestinal motility which can reduce fluid and electrolytes. Methods: This purpose research is to determine the effectiveness and comparison of sapodilla leaf extract syrup with Diapet Kids syrup as antidiarrheal against white mice induced by castor oil. The research used experimental method, the sample was macerated using 70% ethanol as solvent. The thick extract was formulated in syrup dosage form, and stability test was carried out. The syrup doses used were 60 mg/kg BW, 90 mg/kg BW, and 120 mg/kg BW, syrup without extract as a negative control and Diapet Kids syrup as a comparison syrup. The effectiveness of antidiarrhea was carried out by using the diarrhea protection method for 6 hours and comparing the effectiveness of the sapodilla leaf extract syrup with the Diapet Kids syrup. The results of research : is showed that the stability of sapodilla leaf extract syrup met the standard requirements. The data analysis using one way ANOVA then continued with Tukey HSD test. The antidiarrheal activity of sapodilla leaf extract syrup at 90 and 120 mg/kg BW and Diapet Kids syrup have significant different with positive control and syrup of sapodilla leaf extract at 60 mg/kg BW dose (p < 0.05). The comparison of syrup of sapodilla leaf extract dose of 120 mg/kg BW with syrup Diapet Kids was not in significantly difference (p > 0.05). The Sapodilla leaf extract syrup at 90 and 120 mg/kg BW had antidiarrheal activity and Sapodilla leaf extract syrup at 120 mg/kg BW had no significant difference with Diapet Kids syrup (p > 0.05).
EFEKTIVITAS IMUNOSTIMULAN DARI EKSTRAK DAUN BANGUN-BANGUN (Coleus amboinicus L.) PADA TIKUS JANTAN DENGAN STIMUNO SEBAGAI PEMBANDING TAHUN 2021 Anggun Syafitri; Linta Meliala
Jurnal Penelitian Farmasi & Herbal Vol 4 No 1 (2021): Jurnal Penelitian Farmasi & Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v4i1.757

Abstract

Background: This modern society does not know much about the benefits of medicinal plants for health, because people are more familiar with drugs from chemicals. Many plants have imunostimulant activities, one of them is bagun-bangun (Coleus amboinicus L.) which is widely used as a stimulant, carminative, antispasmodic, diuretic, antioxidant and anti-rheumatic.The purpos of thiss research wass to determin the effective of etanol extract of bagun-bangun seeds (EEDB) on imunostimuensitivity lan hypereduction in male white rats compared with stimuno. Methods: The method used experimental. The sample of in this research was bangun-bangun seeds which were take purposivelyy without comparring samples from the other regiions, thenit is extracted by maceration using 80% ethanol and made in the form of thick extract. The results of the study: Imunostimulan efectivity effects were tested on 25 male rats with 5 treatment groups namely, negative group (CMC Na 1%), positive group (stimuno), EEDB group 100mg/kgBW, EEDB group 200mg/kgBW, and EEDB group 300mg/kgBB. Data analysis use the one way ANOVA method.The resultss of the studyy show thatt the most effectiv treatmentt was simvastatin and among the efective dosage ofEECS was a dose of 300mg/KgBW. The resultss of data analysis from the tthree EEDB groups had an effect on cholesterol reducttion due to the sig value <0.05. Based on anovva one way analysis of the five most effective treatmentss was stimuno then EEDB 300mg/kgBW, EEDB 200mg/kgBW, EEDB 100mg/kgBW and CMC Na 1%.EEDB has an effect on imunostimulan reduction but does not give better results than stimuno.
FORMULASI DAN UJI EFEKTIVITAS SEDIAAN GEL DARI EKSTRAK DAUN SUJI (Dracaena agustifolia) PADA TIKUS JANTAN PUTIH SEBAGAI ANTIINFLAMASI Delisma Marsauli Simorangkir; Linta Meliala
Jurnal Penelitian Farmasi & Herbal Vol 4 No 1 (2021): Jurnal Penelitian Farmasi & Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v4i1.766

Abstract

Background: Leaf suji (Dracaena angustifolia) is a native plant of Indonesia that is used as a natural food coloring. However, ethnobotany and pharmacologicalreviews reveaed that this plant had potential as amedicinal ingredient one of them is for anti-inflamatory because it contains saponins that can reduce swelling. Methods: The objective of thE study to determine the gel from suji leaf extract works effectively as an anti-inflmatory against the feet of white male rays and to determine at what concentration the gel preparation from suji leaf ekstract is good as an anti-inflamatory. The method of the study used experimental. The results of the study: The gel preparation of suji leaf extract works effectively as an anti- inflamatory because it can inhibit inflamation in the feet of male white wistar rats well and the concentration of carrageenan induction, which is at a concentration of 20%. Keyword : Gel preparation, daun suji, anti-inflamatory
The FORMULATION AND EVALUATION O FORMULATION AND EVALUATION OF THE PREPARATION OF HAIR TONIC Ethanol Extract of Patchouli Leaves (Pogostemon cablin Benth.) TO OVERCOME HAIR LOSS Bunga Rimta Barus; Linta Meliala
Jurnal Penelitian Farmasi & Herbal Vol 4 No 2 (2022): Jurnal Penelitian Farmasi & Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v4i2.860

Abstract

Nilam leaves contain flavonoids. flavonoids that have activity that can accelerate hair growth and prevent hair loss. The purpose of the study was to make a hair tonic preparation containing patchouli leaf extract and to determine the concentration of the best formula to treat hair loss. Hair tonic is made with nilam leaf extract at concentrations of 5%, 10%, 15%. The ingredients for making Hair Tonic include propylene glycol, propyl paraben, methyl paraben, menthol, sodium metabisulfite, 96% ethanol, Ol. Rosae, Aquades. The method of the study an experimental method with extraction by maceration for 5 days and remaceration for 2 days using 96% ethanol as solvent. Evaluation of Hair Tonic preparations includes homogeneity, pH, organoleptic, viscosity, irritation, preference, and hair growth effectiveness test. The effectiveness test on hair growth in rabbits was carried out on 5 rabbits with 5 treatment groups, namely, positive control group Hair Tonic nature, negative control group, 5% concentration group, 10% concentration group, and 15% concentration group. The analysis of the data on growth testing using One Way Anova. Hair growth data on day 12 were positive control 0.95 mm, negative control 0.03 mm, formula 1 (5%) 0.08 mm, formula 2 (10%) 0.13 mm, formula 3 (15%) 0.83mm. The best formula to treat hair loss is hair tonic with a concentration of 15% nilam leaf ethanol extract. It can be concluded that the greater the concentration of nilam leaf extract given to each treatment, the faster the hair growth.
PENYULUHAN TENTANG MANFAAT DAUN SEDUHAN KOPI ROBUSTA DALAM MENURUNKAN TEKANAN DARAH PENYAKIT HIPERTENSI DI PUSKESMAS BIRU-BIRU Linta Meliala
Jurnal Pengabdian Masyarakat Putri Hijau Vol 1 No 1 (2020): Jurnal Pengabdian Masyarakat Putri Hijau
Publisher : INSTITUT KESEHATAN DELI HUSADA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (477.271 KB) | DOI: 10.36656/jpmph.v1i1.530

Abstract

Background :A diuretic is a drug that can increase the speed of urine volume. The diuretic term has two meanings, the first being indicating increased volume the urine produced and the second shows the amount of ingested substances ingested in water. The caffeine in coffee can cause a weak diuretic because it increases glomerular filtration and decreases inatrium reabsorbs in the renal tubules. Robusta coffee beans are coffee beans that are very easy to grow and easier to harvest, because these coffee beans are less sensitive to climate, so they will always be there to be harvested and this robusta coffee plant has a lot of fruit. This research is meant to find out robusta’s (Coffeacanephora) brew effect on the urine profile and urine volume of the rat white. Method : Samples were 20 male white rats as test animals and were divided into five groups of four in each The positive control group using furosemide 5,04 mg/kgbb, CMC Na 0,5 % is given as a negative control group and than group treatment of an brewing coffee with a dose of 600, 300, 150 mg/kgbb oral injection. Urine measurements were done on the hour to 1, 2, 3, 4, 5, and 6. Result :The study shows robusta coffee brewing with a dose of 600 mg/kgbb shows increased urine volume compared to the dose of 300, and 150 mg/kgbb. Conclusion :robusta coffee seduces have a diuretic effect on male white rat no better than furosemide.
PENYULUHAN TENTANG MANFAAT RUMPUT MUTIARA TERHADAP PENYEMBUHAN PENYAKIT REMATIK PADA USIA 40 TAHUN KE ATAS DI PUSKESMAS DELI TUA Linta Meliala; Palas Tarigan
Jurnal Pengabdian Masyarakat Putri Hijau Vol 2 No 1 (2021): Jurnal Pengabdian Masyarakat Putri Hijau
Publisher : INSTITUT KESEHATAN DELI HUSADA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (201.913 KB) | DOI: 10.36656/jpmph.v2i1.597

Abstract

Rheumatism. are sicknesses that assault joints and designs issues in around joints.Rheumatic illnesses that are frequently found are osteoarthritis because of degeneration or maturing processes, rheumatoid joint inflammation, immune system infections and gout because of high uric corrosive. In the older, this illness regularly happens with the goal that it now and then causes aggravations in the personal satisfaction in the old. As a general rule, the indications of stiffness in every quiet are diverse because of contrasts in the resistant reaction of every individual. Coming up next are the most well-known side effects found in rheumatic sicknesses, in particular: joint agony, expanding in the joints, firmness in the joints, warmth and redness in the joint region, weakness, fever, weight reduction. Illnesses ailment can be forestalled and furthermore gave treatment health,with counseling.this is normal knowledge.elderly and their famil can work on with regards to ailment this strategy utilized in. advising iniiskaji.tindak(action research).The result from augmentation ini is there is an increment in the information on the old with regards to ailment, anticipation and treatment.
PENYULUHAN TENTANG PENGGUNAAN EKSTRAK RIMPANG KUNYIT UNTUK PENGOBATAN DIARE DI PUSKESMAS TANJUNG MORAWA Linta Meliala; Angga Nugraha Sanjaya
Jurnal Pengabdian Masyarakat Putri Hijau Vol 2 No 1 (2021): Jurnal Pengabdian Masyarakat Putri Hijau
Publisher : INSTITUT KESEHATAN DELI HUSADA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (339.927 KB) | DOI: 10.36656/jpmph.v2i1.667

Abstract

The instructions on the utilization of turmeric rhizome extricate for the treatment of loose bowels at the Tanjung Morawa Wellbeing Center means to apply the data and improvements that have been acquired by understudies in more extensive conversations in the neighborhood. Looseness of the bowels or otherwise called gastroenteritis is one of the most well-known infections locally. The justification for holding this PKM is to get data about the utilization of turmeric separate for the treatment of the runs at the Tanjung Morawa Wellbeing Center. The runs is typically portrayed by the recurrence of defecations that surpass the ordinary recurrence, watery consistency, intense and persistent. Intense looseness of the bowels is portrayed by diseases brought about by Escherichia coli, Shigella sp, Salmonella sp, infections, amoebic microscopic organisms, and can likewise be brought about by bacterial poisons, for example, Staphylococcus aureus, Clostridium welchii that sully food, while constant the runs is related with gastrointestinal problems. . Turmeric rhizome is a plant that can be utilized as conventional medication. One sort of plant that can be utilized for the treatment of diarrheal infection is turmeric (Curcuma domestica Val.)
PENYULUHAN TENTANG KULIT BATANG SALAM SEBAGAI OBAT ANTIDIARE DI PUSKESMAS PATUMBAK Bunga Rimta Barus; Delisma Marsauli Simorangkir; Linta Meliala; Anggun Syahfitri
Jurnal Pengabdian Masyarakat Putri Hijau Vol 2 No 2 (2022): Jurnal Pengabdian Masyarakat Putri Hijau
Publisher : INSTITUT KESEHATAN DELI HUSADA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (553.15 KB) | DOI: 10.36656/jpmph.v2i2.823

Abstract

Counseling on the efficacy of the bark of salam which aims to provide benefits about healing diarrhea at the Patumbak Public Health Center in one of the Deli Serdang districts aimed at children aged 6-17 years, by applying promotive and preventive nature through planning, mobilization, implementation, monitoring , control and appraisal. Counseling on the efficacy of the bark of salam at the Public Health Center of Patumbak, Deli Serdang Regency is aimed at increasing understanding to children aged 6-17 years, as well as parents who accompany their children, so that they can identify the symptoms of diarrhea, so that it can prevent or treat it, and malaise. - children and their parents can know the importance of monitoring their children's diet, which is healthy, which parents must take care of. Counseling will be carried out in a lecture style with conditions with discussion and brain storming that stimulates the counseling atmosphere. The evaluation of the activities was assessed from the support of the Patumbak Health Center, the timeliness of implementation, the facilities used, the number of participants who attended the counseling and the participation of the participants. Counseling participants were invited to express opinions, especially the problems faced at the Patumbak Health Center regarding anti-diarrhea so that solutions could be sought together. The results obtained from children and their parents after receiving counseling can understand well the benefits of counseling from the Patumbak Public Health Center regarding the use of the benefits of bay bark for healing. knowledge of the importance of health for their children, Families are willing to provide education and enthusiasm about the importance of the benefits of using bay bark, Parents of children and children aged 6-17 years after receiving counseling can understand well the benefits of counseling from the Patumbak Public Health Center regarding the utilization of the efficacy of the bark of salam for antidiarrheal disease in children aged 6-17 years, which has been described in their minds as just eating delicious food but not necessarily healthy for the body for all children. However, after following the counseling, children – children aged 6-17 years d can understand more fully the benefits of counseling. Community Health Center cadres, who have been providing services to children only in moderation, can change well by providing innovative promotions.
Co-Authors Angga Nugraha Sanjaya Anggun Syafitri Anggun Syafitri Anggun Syahfitri Ariani, Peny Atika Patnisuri Bunga Rimta Barus Bunga Rimta Barus Delisma Simorangkir Delisma Simorangkir Simorangkir Hengki Frengki Manullang Linda Margata Masria Phetheresia Sianipar Nerdy, Nerdy Palas Tarigan Pintata Sembiring Pintata Sembiring Puji Lestari PUJI LESTARI Selamat Ginting Sofia Eliasari Br Bangun Tedy Kurniawan Bakri Viktor Edyward Marbun Vriezka Mierza Winda Sari