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Contact Name
Ripai Siregar
Contact Email
ripaisiregar1994@gmail.com
Phone
+6282274129993
Journal Mail Official
agngprwr@gmail.com
Editorial Address
Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua Jalan Besar Deli Tua No. 77, Kabupaten Deli Serdang, Sumatera- Utara
Location
Kab. deli serdang,
Sumatera utara
INDONESIA
Jurnal Penelitian Farmasi dan Herbal
ISSN : -     EISSN : 26547619     DOI : 10.36656/jpfh
Core Subject : Health,
Aims and Scope The Pharmaceutical & Herb Research Journal is a scientific journal published by Institut Kesehatan Deli Husada which publishes research journals in the field of pharmacy. Indonesia has a lot of natural resources that have the potential to have pharmacological effects. This journal is a place for researchers in the field of pharmacy to be able to publish their researches in 2 main areas, namely Pharmacy and Herbs In the Pharmacy area, accepted research articles include: • Pharmaceutical Biology • Pharmaceutical Chemistry • Pharmacology • Pharmaceutical Technology While the Herb area includes • Herb medicinal formulations from natural ingredients The Pharmaceutical & Herb Research Journal can also be a forum for informations and sources of knowledge related to the field of pharmaceutical science and herb medicine in Indonesia.
Articles 193 Documents
FORMULASI DAN UJI STABILITAS LOTION SARI BUAH TOMAT (licopersicon esculentum mill) KOMBINASI KUNYIT (Curcuma domestica Vall) SEBAGAI PELEMBAB KULIT Nina Irmayanti Harahap
Jurnal Penelitian Farmasi & Herbal Vol 3 No 2 (2021): Jurnal Penelitian Farmasi & Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v3i2.652

Abstract

Antioxidants is contained in various types of fruit and vegetables included of juice tomatoes (Lycopersicum esculentum Mill)that have nutritional value and benefits for the body like lycopene, and vitamin C as antioxidants. Lycopene is function as a strong antioxidant to control free radical. Tumeric (Curcuma domestica Vall) is known have enough curcumin and strong antioxydants content too, and so it has some pharmacological effects. Tomatoes and Tumeric extract (EKSBT) can be made as pharmaceutical preparations in hand and body lotion (H&B lotion),because antioxidants are important components that are used for body protection from ultra violet light and can be applied in the form of a lotion. The purpose of this study was to saw the stability of the H&B lotion combination of that Variations.Combination tomatoes and turmeric extract formulated with concentrations lotion are of 5%, 10%, and 15%. The lotion of EKSBT these combination were evaluated some test there are organoleptic, homogeneity, pH test, spreadability, irritation and preference test.EKSBT combination can be formulated into lotion preparations. The various of all concentrations lotion EKSBT showed that stable during instorage, give a homogeneous yellow color with pH of 5-6 and a spread of 5-6 cm, does not irritate the skin and is preferably the volunteer.Physical stability EKSBT lotion test all concentration are stable, the preferred test of odor, easy to be smeared and moisturizing shows that the most preferred EKSBT lotion is the highest concentration 15%.
FORMULASI KRIM PEWARNA RAMBUT EKSTRAK ETANOL DAUN HATI UNGU (Tradescantia pallida) Wahyudi Wahyuni
Jurnal Penelitian Farmasi & Herbal Vol 3 No 2 (2021): Jurnal Penelitian Farmasi & Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v3i2.653

Abstract

Hati ungu contain natural dyes derived from anthocyanins. Anthocyanin is a pigment that is classified into flavonoids which in general gives a specific color to plants. The natural color found in this purple liver plant can be used as a natural coloring agent in cosmetics. Hair dye cream preparations were chosen because they are popular and easy to use. The purpose of this study is to determine ethanol extracts of hati ungu can be made as a preparation for hair dye creams, and which formula gives the best color. The research method was carried out including making ethanol extract of hati ungu (Tradescantia pallida) by maceration using 96% ethanol.The results of research on 4 hair dye cream formulations, preparations met the test requirements. The results of the basting test on hair with a vulnerable time for 1-4 hours showed that at the fourth hour the results of hair coloring give a good color. In the color stability test of washing, after washing with shampoo fifteen times all four formulas have a fixed color up to 9 times washing. The results of color stability to sunlight show that after the hair is exposed to sunlight the color looks slightly changed, hair color becomes darker than before. From the results of the research the concentration of ethanol extract of hati ungu which gives the best purple color is ethanol extract cream of hati ungu 20%.
Perbandingan Konsentrasi Ekstrak Etanol Daun Bau-Bau (Chromolaena odorata (L.) King & H.E. Robins) Dan Ekstrak Etanol Temu Putih (Curcuma zedoria (Berog) Rosc) terhadap Penyembuhan Luka Bakar pada Kelinci Bunga Rimta Barus
Jurnal Penelitian Farmasi & Herbal Vol 3 No 2 (2021): Jurnal Penelitian Farmasi & Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v3i2.654

Abstract

Daun Bau-Bau (Chromolanea odorata (L) King & H Robins) mengandung senyawa minyak atsiri, flavonoid, alkaloid, fenol, saponin, dan tannin. Temu putih (Curcuma zedoria (Berog.)Rosc) mengandung kurkumin, tritepenoid, flavonoida, saponin dan minyak astiri. Tujuan penelitian ini untuk membandingkan efektivitas Ekstrak Etanol Daun Bau-Bau dan Ekstrak Etanol Rimpang Temuputih. Ekstraksi sampel menggunakan etanol 96%. Hasil ekstraksi dibagi 7 kelompok konsentrasi yaitu 25%,15%, 10% dan Aquadest sebagai kontrol negatif.Menurut Hasil Analisis Data Anova One Way (Uji Tuckeys B) Diameter luka bakar dari hari pertama sampai ke 14 hari pengamatan mengalami penurunan, kelompok kelinci yang diberi perlakuan dengan ekstrak daun bau-bau konsentrasi 25% pada hari ke- 14 diameter luka bakar mengalami perubahan dengan efektifitas 2 cm (p=0,0). Pada kelompok ekstrak etanol temuputih konsentrasi 25% pada hari ke-14 diameter luka bakar mengalami perubahan dengan efektifitas 1,08 cm (p=0,64). Ekstrak Etanol Daun Bau-Bau Lebih Efektif untuk menyembuhkan luka bakar dibandingkan dengan Ekstrak Etanol Temu Putih.
FORMULASI EKSTRAK BUAH NAGA MERAH (Hylocereus polyrhizus ) SEBAGAI SEDIAAN PEMERAH PIPI (BLUSH ON) Herviani Sari; Firdaus Fahdi
Jurnal Penelitian Farmasi & Herbal Vol 3 No 2 (2021): Jurnal Penelitian Farmasi & Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v3i2.655

Abstract

Dragon fruit contain high antosianin, sources of antosianin can be optained from pink colored fruit and vegetables to red. The natural properties of antosianin can be used as natural dyes in cosmetic preparation were chosen because it is a cosmetic that is quite popular and most comfortable to use. The purpose of this research is to find out whether dragon fruit can be blush on, not irritated and to find out the best formulations. The methode of this research was done by making dragon fruit extract by maceration for 24 hours using etanol. The extract formulation used is 15%, 25%, and 40%. Ingridienst for making blush on include kaolin, parrafin liquid, zink oxyd, and talcum. Evaluation of blus on preparations include homogenty, pH, dispersion, irritation, polish and hedonic. The results of research 3 blush on formulation, the preparation met the homogenity test with no vissible coarse grains and particlesevently mixed. The pH of the preparation producted is still in the normal pH range of spearat evenly and easily attached to the skin, with each application three time polishing. Based on the favorite test after processing statistical data, formulation the most preferred panelish is blush on formulation 3. Key words: Dragon fruit, blush on, antosianin.
FORMULASI SEDIAAN MASKER GEL Peel-off EKSTRAK DAUN KECOMBRANG (Etlingera elatior) SEBAGAI PERAWATAN PADA KULIT WAJAH Bunga Mari Sembiring
Jurnal Penelitian Farmasi & Herbal Vol 3 No 2 (2021): Jurnal Penelitian Farmasi & Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v3i2.656

Abstract

Kecombrang (Etlingera elatior) leaves contain flavonoid compounds, saponins, alkoloid, and tannins. Based on the compounds owned kecombrang leaves can be used as a peel off gel mask. The purpose of this study was to make a peel off gel mask formulation of kecombrang (Etlingera elatior) leaf extract as a treatment for facial skin. The gel peel off mask formulation was made with 4 formulations, F0 = 0%, FI = 10%, FII = 15%, FIII = 20%. Extraction method is done using maceration method with 96% ethanol solvent. Evaluation of peel off gel mask preparations, including organoleptic tests (color, odor, shape), pH measurement of preparations, homogeneity test, dry time test, spreadability test. Peel off gel mask preparations that have effectiveness as treatments for facial skin are FIII formulations with a concentration of 15% that meet the evaluation test requirements, and positive control (Naturgo) which has had better effectiveness test results. The results of the evaluation test of peel off gel mask preparation, including organoleptic test (color, odor, shape), pH measurement of the preparation, homogeneity test, dry time test, dispersion test according to the gel preparation parameters.
PERBANDINGAN SEDIAAN SIRUP ANTIDIARE EKSTRAK DAUN SAWO (Manilkara zapota L.) DENGAN SEDIAAN SIRUP ANTIDIARE DI PASARAN TERHADAP MENCIT PUTIH (Mus musculus L.) Linta Meliala; Anggun Syafitri
Jurnal Penelitian Farmasi & Herbal Vol 4 No 1 (2021): Jurnal Penelitian Farmasi & Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v4i1.746

Abstract

Background: the Sapodilla leaves (Manilkara zapota L.) contain chemical compounds of tannins and flavonoids which have antidiarrheal activity. Tannins are astringent and flavonoids inhibit intestinal motility which can reduce fluid and electrolytes. Methods: This purpose research is to determine the effectiveness and comparison of sapodilla leaf extract syrup with Diapet Kids syrup as antidiarrheal against white mice induced by castor oil. The research used experimental method, the sample was macerated using 70% ethanol as solvent. The thick extract was formulated in syrup dosage form, and stability test was carried out. The syrup doses used were 60 mg/kg BW, 90 mg/kg BW, and 120 mg/kg BW, syrup without extract as a negative control and Diapet Kids syrup as a comparison syrup. The effectiveness of antidiarrhea was carried out by using the diarrhea protection method for 6 hours and comparing the effectiveness of the sapodilla leaf extract syrup with the Diapet Kids syrup. The results of research : is showed that the stability of sapodilla leaf extract syrup met the standard requirements. The data analysis using one way ANOVA then continued with Tukey HSD test. The antidiarrheal activity of sapodilla leaf extract syrup at 90 and 120 mg/kg BW and Diapet Kids syrup have significant different with positive control and syrup of sapodilla leaf extract at 60 mg/kg BW dose (p < 0.05). The comparison of syrup of sapodilla leaf extract dose of 120 mg/kg BW with syrup Diapet Kids was not in significantly difference (p > 0.05). The Sapodilla leaf extract syrup at 90 and 120 mg/kg BW had antidiarrheal activity and Sapodilla leaf extract syrup at 120 mg/kg BW had no significant difference with Diapet Kids syrup (p > 0.05).
UJI EFEKTIVITAS EKSTRAK ETANOL HERBA KROKOT (Portulaca oleracea L.) SECARA Topical UNTUK Reepitelisasi PENYEMBUHAN LUKA INSISI PADA TIKUS PUTIH (Rattus norvegicus) Rani Ardiani
Jurnal Penelitian Farmasi & Herbal Vol 4 No 1 (2021): Jurnal Penelitian Farmasi & Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v4i1.750

Abstract

The krokot is a weed that usually grows in plantations. In scientific language, purslane is called Portulaca oleracea L. Purslane is well-known as a nutritious plant in several countries such as China, Mexico, and Greece. In Indonesia, purslane is also known to have uses, or a substitute for ginseng. This aims of the study to determine the effectiveness of purslane herb ethanol extract ointment on wound healing in white rats. This research was conducted using an experimental method. In this study, phytochemical screening and simplicia characterization were carried out. Incision wound healing effect was tested on 25 male white rats with 5 treatment subgroups, namely positive control, negative control, purslane herb ethanol extract ointment 10%, purslane herb ethanol extract ointment 20%, purslane herb ethanol extract ointment 30%. The ointment base used is Vaseline album, liquid paraffin, and solid paraffin. All formulations of purslane herb 10%, 20% and 30%, met the requirements for evaluation of ointment preparations. Phytochemical screening results showed positive containing flavonoids, tannins and saponins. The results of the characterization of purslane herb simplicia powder obtained water content of 8.37%, water soluble extract content of 11.35%, ethanol soluble extract content of 10.99%, total ash content of 7.46% and acid insoluble ash content of 0.88%. The average results of observation of incision wounds in white rats were concentrations of 10% (22 mm) for 14 days, 20% (0.1 mm) for 14 days, 30% (0.04 mm) for 14 days. While the positive control (betadine ointment) was (0 mm) and the negative control (ointment base) was (0.42 mm). It can be concluded that purslane herb ethanol extract can provide effectiveness and antioxidants for wound healing in white rats. The purslane herb 30% ethanol extract has almost comparable effectiveness with betadine ointment in healing incisional wounds in white rats.
FORMULASI DAN PERBANDINGAN UJI STABILITAS FISIK SEDIAAN GEL EKSTRAK DAUN KACAPIRING (GARDENIA JASMINOIDES ELLIS) DAN ACNES SPOT GEL DIPASARAN Sofia Eliasari
Jurnal Penelitian Farmasi & Herbal Vol 4 No 1 (2021): Jurnal Penelitian Farmasi & Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v4i1.754

Abstract

Background: The gardenia jasminoides ellis contain flavonoids which have antioxidant and the antibacterial effects. Traditional use requires a long preparation, so it is necessary to formulate preparations that are more practical and durable in storage. The gel preparation was chosen in the formulation because it dries easily, forms a film that is easy to wash off and provides a cooling feeling on the skin. The gel component affects of the stability of the gel. The stability tests need to be carried out to ensure the quality, safety and efficacy of the gel meets the expected specifications and is stable during storage. The aims of the study to determine the difference in of the physical stability of the gel preparation of Gardenia jaminoides ellis and acnes spot gel on the market and determine the concentration of gardenia jasminoides ellis extract which has the best physical stability. Methods: The research of the method is experimental laboratory. Simplicia was extracted using 96% ethanol as solvent. The extract was formulated in gel dosage form with a concentration of 0.5% (FI), 1% (FII) and 1.5% (FIII). The results of study: The physical stability of the preparation tested by organoleptic, homogeneity, pH test, adhesion test, viscosity test, hedonic test and gel stability test which were compared with gels on the market. The results of the physical stability of the preparation observed at room temperature, the pH of the market gel was more acidic than the gardenia jasminoides ellis extract. The viscosity of formula 3 is higher in viscosity. In the stability test, it was seen that from the three formulas and gels on the market there was no change in shape, color and odor.
EFEKTIVITAS IMUNOSTIMULAN DARI EKSTRAK DAUN BANGUN-BANGUN (Coleus amboinicus L.) PADA TIKUS JANTAN DENGAN STIMUNO SEBAGAI PEMBANDING TAHUN 2021 Anggun Syafitri; Linta Meliala
Jurnal Penelitian Farmasi & Herbal Vol 4 No 1 (2021): Jurnal Penelitian Farmasi & Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v4i1.757

Abstract

Background: This modern society does not know much about the benefits of medicinal plants for health, because people are more familiar with drugs from chemicals. Many plants have imunostimulant activities, one of them is bagun-bangun (Coleus amboinicus L.) which is widely used as a stimulant, carminative, antispasmodic, diuretic, antioxidant and anti-rheumatic.The purpos of thiss research wass to determin the effective of etanol extract of bagun-bangun seeds (EEDB) on imunostimuensitivity lan hypereduction in male white rats compared with stimuno. Methods: The method used experimental. The sample of in this research was bangun-bangun seeds which were take purposivelyy without comparring samples from the other regiions, thenit is extracted by maceration using 80% ethanol and made in the form of thick extract. The results of the study: Imunostimulan efectivity effects were tested on 25 male rats with 5 treatment groups namely, negative group (CMC Na 1%), positive group (stimuno), EEDB group 100mg/kgBW, EEDB group 200mg/kgBW, and EEDB group 300mg/kgBB. Data analysis use the one way ANOVA method.The resultss of the studyy show thatt the most effectiv treatmentt was simvastatin and among the efective dosage ofEECS was a dose of 300mg/KgBW. The resultss of data analysis from the tthree EEDB groups had an effect on cholesterol reducttion due to the sig value <0.05. Based on anovva one way analysis of the five most effective treatmentss was stimuno then EEDB 300mg/kgBW, EEDB 200mg/kgBW, EEDB 100mg/kgBW and CMC Na 1%.EEDB has an effect on imunostimulan reduction but does not give better results than stimuno.
ANALISIS FAKTOR YANG BERHUBUNGAN DENGAN KEPATUHAN PEGAWAI INSTALASI FARMASI DENGAN PENGGUNAAN ALAT PELINDUNG DIRI ( APD) DI RSUD KISARAN TAHUN 2021 Sulasmi Sulasmi
Jurnal Penelitian Farmasi & Herbal Vol 4 No 1 (2021): Jurnal Penelitian Farmasi & Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v4i1.759

Abstract

Background: PPE is a tool used to protect yourself or the body against the dangers of work accidents. The factors that influence adherence are K3 training, knowledge, behavior, age, gender. The Pharmacy Installation is a part of the hospital that manages the hospital's pharmaceutical needs, medicines, (BMHP), and medical devices. handling and controlling B3 as well as hospital injection drugs which of course have a risk of exposure to hazardous biological substances (biohazard). The purpose of this study was to analyze the factors associated with the compliance of pharmacy installation staff with the use of PPE at Kisaran Regional Hospital in 2021.Methods: This type of research used quantitative research using a cross sectional approach. The number of samples in this study were 30 people. The sample was determined by a simple technique of selecting the sample using purposive sampling. The results of the study: The data was collected using a questionnaire sheet and then processed using a statistical computer program with the chi square test with a significance level of α = 0.05 (95%). The results of the study found that the relationship of compliance with PPE use with age (p = 0.002 <α 0.05), gender (p = 0.127> α 0.05), K3 training (p = 0.004 <α 0.05), Knowledge (p = 0.018 <α 0.05) and Behavior (p = 0.011 <α 0.05). It is recommended for Kisaran Hospital to further improve the Compliance with the Use of PPE, especially for Pharmacy Installation employees.

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