cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
Moondra Zubir
Contact Email
moondrazubir@unimed.ac.id
Phone
-
Journal Mail Official
ijcst.kimia.unimed@gmail.com
Editorial Address
Chemistry Department , State University of Medan Jl. Willem Iskandar Pasar V, Medan Estate Medan, Indonesia
Location
Kota medan,
Sumatera utara
INDONESIA
Indonesian Journal of Chemical Science and Technology
Published by Universitas Negeri Medan
ISSN : 26221349     EISSN : 26224968     DOI : -
Core Subject : Science, Engineering,
Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Energy Materials Science & Nanotechnology
Jurnal ini mempublikasikan artikel di bidang Kimia yang meliputi penelitian dasar dan terapan. Bentuk Publikasi di Indonesian Journal of Chemical Science and Technology : * Artikel * Review (berdasarkan permintaan Dewan Redaksi) * Communication (berdasarkan permintaan Dewan Redaksi)
Arjuna Subject : Kimia(semua kategori) - Kimia (Lain-Lain)
Articles 270 Documents
 23   24   25   26   27 
Antioxidant Activity and Organoleptic Quality of Traditional Batak Dried Arsik Seasoning Pricilia Saruksuk Saruksuk
Indonesian Journal of Chemical Science and Technology (IJCST) Vol. 9 No. 2 (2026): JULY 2026
Publisher : Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24114/ijcst.v9i2.74628

Abstract

Arsik is a traditional Batak cuisine prepared using various spices that contain bioactive compounds with potential antioxidant properties. The development of dried arsik seasoning offers advantages in terms of practicality, shelf life, and product diversification while maintaining the characteristic flavor of traditional arsik. This study aimed to evaluate the antioxidant activity and organoleptic quality of dried arsik seasoning formulated with different proportions of cayenne pepper and candlenut. Three formulations (F1, F2, and F3) were extracted using the maceration method with 96% ethanol and subsequently evaluated for antioxidant activity using the DPPH (2,2-diphenyl-1-picrylhydrazyl) assay. Organoleptic evaluation was conducted by 20 panelists using a 9-point hedonic scale based on color, aroma, taste, and texture attributes. The results showed that formulation F2 exhibited the highest extraction yield (57.1%) and antioxidant activity with a DPPH inhibition value of 70.2%, followed by F3 (68.9%) and F1 (36.3%). Organoleptic assessment indicated that F2 achieved the highest overall acceptance score (7.71), followed by F3 (7.25) and F1 (5.45). The higher antioxidant activity observed in F2 was associated with its balanced composition of spices, particularly cayenne pepper, which is known to contain antioxidant compounds such as phenolics and flavonoids. These findings suggest that formulation F2 is the most promising dried arsik seasoning formulation due to its high antioxidant activity and favorable consumer acceptance.
Antibacterial Activity of Ethanol Extract of Nettle Leaves against Cutibacterium acnes and Pseudomonas aeruginosa Zuhairiah Nasution; Fira Yunita; Murniaty Simorangkir; Saronom Silaban; Nora Susanti
Indonesian Journal of Chemical Science and Technology (IJCST) Vol. 9 No. 2 (2026): JULY 2026
Publisher : Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24114/ijcst.v9i2.75052

Abstract

Acne vulgaris is a common skin disorder associated with the growth of Cutibacterium acnes and Pseudomonas aeruginosa. This study aimed to evaluate the antibacterial activity of ethanol extract of nettle leaves (Urtica dioica) against both bacteria. The extract was obtained by maceration using 96% ethanol and subjected to phytochemical screening. Antibacterial activity was tested using the disc diffusion method at concentrations of 200, 400, and 800 mg/mL. The findings demonstrated that the extract contained alkaloids, phenolics, flavonoids, steroids, and saponins. The inhibition zones against Cutibacterium acnes were 14.17±0.21 mm, 16.03±0.76 mm, and 17.37±1.33 mm, while against Pseudomonas aeruginosa they were 9.63±0.51 mm, 12.23±0.40 mm, and 14.33±0.47 mm, respectively. Statistical analysis showed significant differences among treatments (p<0.05). These findings indicated that Urtica dioica leaf extract may serve as a potential natural antibacterial agent against acne-associated bacteria.
Potential of Alkaloids Isolated from Benzoin Resin (Styrax benzoin) Mutiara Annisa
Indonesian Journal of Chemical Science and Technology (IJCST) Vol. 9 No. 2 (2026): JULY 2026
Publisher : Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24114/ijcst.v9i2.75151

Abstract

Benzoin resin (Styrax benzoin) is a natural product that contains various bioactive compounds, including alkaloids, which have potential antibacterial properties. This study aimed to evaluate the antibacterial potential of alkaloids obtained from benzoin resin against Staphylococcus aureus. Benzoin resin was extracted using the maceration method with 96% ethanol, followed by alkaloid screening using Mayer, Wagner, and Dragendorff reagents. Alkaloids were isolated through chromatographic separation and tested for antibacterial activity using the disc diffusion method at concentrations of 10%, 20%, and 40%. The extraction process yielded 92.13 g of crude extract with an extraction yield of 76.77%. Alkaloid screening showed positive results for all tested reagents, indicating the presence of alkaloid compounds in the extract. The alkaloid isolate exhibited antibacterial activity against Staphylococcus aureus, with inhibition zone diameters of 8.23 ± 0.38 mm, 8.93 ± 0.32 mm, and 12.43 ± 1.33 mm at concentrations of 10%, 20%, and 40%, respectively. Statistical analysis revealed that variations in alkaloid concentration significantly affected antibacterial activity (p < 0.05). These findings suggest that alkaloids derived from benzoin resin possess promising antibacterial potential against Staphylococcus aureus and may serve as a natural source of antibacterial agents.
Phytochemical Screening and Antioxidant Activity of Ethanolic Extracts of Young and Mature Butterfly Pea (Clitoria ternatea) Leaves Using the DPPH Method Amelia Dwi Putri
Indonesian Journal of Chemical Science and Technology (IJCST) Vol. 9 No. 2 (2026): JULY 2026
Publisher : Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24114/ijcst.v9i2.75152

Abstract

Butterfly pea leaves (Clitoria ternatea) are one part of the plant that contains various secondary metabolites and have the potential to serve as a natural antioxidant source. This study aimed to determine the phytochemical content and compare the antioxidant activity of ethanolic extracts of young and mature butterfly pea leaves using the DPPH (2,2-diphenyl-1-picrylhydrazyl) method. The samples were extracted by maceration using 96% ethanol, followed by qualitative phytochemical screening and antioxidant activity testing at concentrations of 20, 40, 60, and 80 μg/mL. The results showed that both extracts were positive for phenolics, flavonoids, tannins, alkaloids, saponins, and steroids, but negative for triterpenoids. The IC₅₀ values of young leaf extract, mature leaf extract, and vitamin C were 80.408, 58.023, and 5.655 μg/mL, respectively. Based on the IC₅₀ values, both extracts were classified as strong antioxidants, while vitamin C was classified as a very strong antioxidant. The mature butterfly pea leaf extract showed higher antioxidant activity than the young leaf extract, indicating that leaf maturity affects the antioxidant potential of butterfly pea leaves.
Zeolite Synthesis From Rice Husk Ash (Oryza Sativa L.) as an NH3 Adsorbent for the Making of Eco-Friendly Cat Litter Sri Murda Niati
Indonesian Journal of Chemical Science and Technology (IJCST) Vol. 9 No. 2 (2026): JULY 2026
Publisher : Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24114/ijcst.v9i2.75164

Abstract

This study aims to synthesize zeolite from rice husk ash (Oryza sativa L.) as an ammonia (NH₃) adsorbent for eco-friendly cat litter applications. The hydrothermal method was used to produce zeolite from rice husk ash and aluminum hydroxide, varying the Na₂SiO₃:Al₂O₃ ratio. The synthesized zeolites were characterized physically and chemically through moisture content, ash content, and FTIR spectroscopy analyses. Ammonia adsorption efficiency was assessed using UV-Vis spectrophotometry at initial concentrations from 5% to 25%. All zeolite variants succeeded in reducing ammonia content, with final filtrate concentrations increasing at higher initial levels. Zeolite 3 exhibited the most stable adsorption efficiency, ranging from 33% (at 5% initial NH₃) to 18% (at 25% NH₃), and was also the most crystalline with the lowest moisture and ash contents. These results indicate that synthetic zeolite derived from rice husk ash, particularly with the optimal ratio found in Zeolite 3, is highly suitable for use as an eco-friendly cat litter material, offering effective ammonia control and supporting sustainable agricultural waste utilization.
Machine Learning–Driven Discovery of Dietary Polyphenol DPP-4 Inhibitors via Molecular Docking Nur Laily Harfita; Ahmad Faisal Nasution; Zuliana Amalia Amalia; Joceline Schellenberg W; Rahayu
Indonesian Journal of Chemical Science and Technology (IJCST) Vol. 9 No. 2 (2026): JULY 2026
Publisher : Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24114/ijcst.v9i2.75390

Abstract

T2DM is a chronic metabolic disorder of rising global prevalence, in which DPP-4 serves as a key therapeutic target through its role in incretin hormone degradation. This study aimed to identify polyphenolic compounds derived from dietary sources as potential DPP-4 inhibitors through an in silico pipeline integrating machine learning (ML) and molecular docking. The bioactivity dataset for DPP-4 was retrieved from ChEMBL (CHEMBL284), processed into a binary classification dataset, and represented using 2048-bit Morgan fingerprints combined with five RDKit descriptors. Six ML models were integrated into a soft-voting ensemble, achieving a Matthews correlation coefficient (MCC) of 0.8334 and an AUC-ROC of 0.9739. Screening of 162 compounds from the Phenol-Explorer database yielded 11 potential active inhibitors. Molecular docking identified hesperetin (−8.548 kcal/mol) as the leading candidate, followed by pelargonidin, daidzein, and naringenin, with key binding residues including Ser209, Glu205/206, Tyr631, Arg125, and Tyr662.
Green Synthesis and Antibacterial Activity of Silver Nanoparticles Using Ethanolic Extract from Clerodendrum fragrans Leaves Murniaty Simorangkir; Indah Sitanggang; Floren Miani Sihotang; David Septian Sibarani
Indonesian Journal of Chemical Science and Technology (IJCST) Vol. 9 No. 2 (2026): JULY 2026
Publisher : Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24114/ijcst.v9i2.75700

Abstract

Green synthesized silver nanoparticles using plant extract (AgNPs) have emerged as promising biomaterials for biomedical applications, particularly as antimicrobial agents. This study aimed to synthesize AgNPs using ethanolic leaf extract of sarang banua (Clerodendrum fragrans) and to evaluate their physicochemical characteristics and antibacterial activity for skin-related applications. C. fragrans leaf contains secondary metabolite bioactive compounds that can be involved in nanoparticle synthesis. In this approach plant-derived phytochemicals functioned as reducing and stabilizing agents. Antibacterial activity was tested using the disc diffusion method followed by determining the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC). The results of the study showed an average diameter of 114 nm with a polydispersity index (PDI) of 0.5, indicating moderate uniformity.The AgNPs showed strong inhibitory activity against Staphylococcus aureus as a representative skin-associated pathogenic bacteria with an inhibition zone of 11.06 mm. The minimum inhibitory concentration value was 3.375 µg/mL, while the minimum bactericidal concentration value exceeded 27 µg/mL, indicating bactericidal effects at higher concentrations. These findings highlight the potential of C. fragrans-mediated AgNPs as biomaterials for skin-related biomedical applications.
Determination of Lead (Pb) Content in Commercial Fruit Juice Drinks Using Atomic Absorption Spectroscopy with Standard Addition Method Yorfan Ruwindya; Desta Aulia Putri; Hana Mayarana; Tri Esti Purbaningtias
Indonesian Journal of Chemical Science and Technology (IJCST) Vol. 9 No. 2 (2026): JULY 2026
Publisher : Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24114/ijcst.v9i2.76235

Abstract

Lead (Pb) is one of the most hazardous heavy metals that may contaminate fruit juice through environmental pollution, raw materials, processing, and packaging. Continuous exposure to Pb poses significant health risks due to its cumulative toxicity. This study aimed to determine the Pb concentration in commercially packaged fruit juice using Atomic Absorption Spectroscopy (AAS). Samples were prepared by wet digestion using nitric acid, followed by Pb determination employing the standard addition method to minimize matrix interference. The analytical method was evaluated through linearity, limit of detection (LOD), limit of quantification (LOQ), precision, and accuracy. The calibration curve exhibited excellent linearity within the investigated concentration range. The Pb concentration in the analyzed sample was found to be 0.15 mg kg⁻¹, which is below the maximum permissible limit established by the Indonesian National Standard (SNI 3719:2014). The method showed satisfactory analytical performance with an LOD of 0.1773 mg L⁻¹, an LOQ of 0.5910 mg L⁻¹, a relative percent difference (RPD) of 2.33%, and a recovery of 105.73%. These results demonstrate that the standard-addition AAS method provides a reliable quantitative determination of Pb in fruit juice matrices.
Analysis of Collision Theory in the Production of Candlenut Oil Biodiesel Using a Zeolite-KOH Catalyst Moondra Zubir; Joice Evelyn Simamora; Gian Devina Gracia Nehe; Mardiyah Tsani
Indonesian Journal of Chemical Science and Technology (IJCST) Vol. 9 No. 2 (2026): JULY 2026
Publisher : Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24114/ijcst.v9i2.76785

Abstract

The methanol-to-oil ratio is one of the most important factors affecting biodiesel production through transesterification. This study investigated the effect of different methanol-to-oil ratios (1:2, 1:4, 1:6, 1:8, and 1:10) on biodiesel production from candlenut oil (Aleurites moluccanus L.) using KOH-activated zeolite catalyst from a collision theory perspective. Biodiesel was produced through transesterification at 60–65 °C with a stirring speed of 300 rpm for 1 h. The resulting biodiesel was characterized based on yield, volume, and density. The results showed that increasing the methanol-to-oil ratio up to 1:6 increased biodiesel yield and improved product quality. The highest yield of 95.47% was obtained at a ratio of 1:6 with a density of 0.850 g/mL. Further increases in methanol concentration reduced biodiesel yield. Based on collision theory, the 1:6 ratio provided the optimum condition for effective molecular collisions during transesterification.
From Biowaste to Buffering Agent: Chicken Eggshell Filtrate in Controlling pH and Acid–Base Equilibrium Based on Eggshell Thickness Moondra Zubir; Awal Syahputra; Irene Zalukhu; Muhammad Fadhil Arsalan; Mutiasary Pohan; Walker Zakaria Hutagalaung
Indonesian Journal of Chemical Science and Technology (IJCST) Vol. 9 No. 2 (2026): JULY 2026
Publisher : Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24114/ijcst.v9i2.76786

Abstract

In weak acid tissue culture system, chicken eggshell biowaste containing 95% CaCO₃ could serve as an economical and green buffering agent. This study investigates the influence of eggshell filtrate thickness (1 cm, 2 cm and 3 cm) on pH improvement and acid–base balance in acetic acid (vinegar) and citric acid (lime juice) solutions. The filtrate media were prepared by cleaning, drying and crushing eggshells which organize the egg shell in columns with different thickness. Then, each acid solution was applied to the filtrate, using a range of pH values recorded before and after treatment. Filtrate with greater thickness consistently yielded a higher pH, regardless of the samples, and the 3 cm medium produced the highest rise in both samples. This is due to the higher interaction between acid solutions and CaCO₃, which allows for neutralization and shifting the chemical equilibrium toward less acidic conditions. The findings confirm that eggshell thickness significantly affects buffering efficiency. Therefore, eggshell-derived filtrate can serve as a sustainable and effective material for pH control in weak acid systems.

Page 27 of 27 | Total Record : 270

 23   24   25   26   27 

Filter by Year

2018 2026


Reset
Filter By Issues
All Issue Vol. 9 No. 2 (2026): JULY 2026 Vol. 9 No. 1 (2026): JANUARY 2026 Vol. 8 No. 2 (2025): JULY 2025 Vol. 8 No. 1 (2025): JANUARY 2025 Vol 7, No 2 (2024): JULY 2024 Vol. 7 No. 2 (2024): JULY 2024 Vol. 7 No. 1 (2024): JANUARY 2024 Vol 7, No 1 (2024): JANUARY 2024 Vol 6, No 2 (2023): JULY 2023 Vol. 6 No. 2 (2023): JULY 2023 Vol 6, No 1 (2023): JANUARY 2023 Vol 5, No 2 (2022): JULI 2022 Vol 5, No 1 (2022): JANUARI 2022 Vol 4, No 2 (2021): JULI 2021 Vol 4, No 1 (2021): JANUARY 2021 Vol 3, No 2 (2020): July 2020 Vol 3, No 1 (2020): January 2020 Vol 2, No 2 (2019): July 2019 Vol 2, No 1 (2019): January 2019 Vol 1, No 1 (2018): Juli 2018 More Issue