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INDONESIA
Indian Journal of Forensic Medicine & Toxicology
Published by Official Organ of Indian Association of Medico-Legal Expert
ISSN : -     EISSN : -     DOI : -
Core Subject : Health,
Public Health
Arjuna Subject : Kedokteran - Epidemilogi
Articles 5,497 Documents
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Study of Lipid Profiles levels in Iraqi children with GH Deficiency Before and after 6 Months GH Replacement Therapy Mithal R Alkubaisi1 , Hameed Hussein Ali2 , Fakhri J. Al-Dalla Ali1 , Abbas M. Rahmah3
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.12308

Abstract

This present study aimed to quantify serum lipid levels [Total cholesterol (TC), Triglyceride (TG), LowDensity Lipoprotein –cholesterol (LDL-c), Very Low Density Lipoprotein –cholesterol( VLDL-c), HighDensity Lipoprotein–cholesterol (HDL–c) ] quantified before and after 6 months of treatment in Iraqichildren with HGH deficiencyThis study was conducted at the National Center for Diabetes Treatment and Research of the MustansiriyaUniversity in Baghdad and for the period from, (October 2016 to July 2017). The study included 200 samplesdivided into two groups. The patient group included 100 children with short stature including 52 males and48 females with their age ranged from 5 to 12 years . For comparison, 100 samples (50 females and 50males) of healthy children corresponding to patients with sex, age were selected as control group.The results of the study showed Serum (TC), (TG), (LDL-C) and (VLDL) levels had a highly significantlyincreased in children GHD group when compared with controls group (P<0.001).Regarding serum (HDL-C) levels there was a highly significantly decreased in children GHD group whencompared with healthy children (P<0.001) before treatment, and after 6 months of treatment a decrease infat levels was observed in patients [ (TC), (TG) and (LDL-C), (VLDL), very significantly (p <0.001), whiletheir HDL-C level was higher than before treatment .To distinguish between GHD patients and the control group, the Receiver Operator Curve (ROC) analysisshowed a descending order of significance for the indicators that showed significant differences beforetreatment. The serum level of LDL-C was 0.77, followed by (TG) (0.637 ) ,(VLDL-C) (0.637),( TC) (0.626),and ( HDL-C) (0.614) respectively [this means that all variables managed to occupy a significant region ofROCIt was concluded from this study that there was a significant increase (P <0.001) in serum TG, TC, LDL-Cand VLDL-C, while the level of HDL-C in the blood decreased significantly in GHD children comparedwith healthy children. After 6 months of treatment rhGH has improved the lipid profile of children withgrowth hormone deficiency.
The Association between The Thickness of the Endometrium at the Day of Human Chorionic Gonadotrophin Injection and the Outcome Intracytoplasmic Sperm Injection Zainab Alkhafajy1 , Zainab Abd alkathem fatnan2 , Hayfaa Dinar Jaber AL Habeeb3
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.12309

Abstract

Background: Clinically during ICSI, controlled ovarian stimulation (COS) is a famous way to increasethe number of mature oocytes picked up. This method must be asseeed with a substantial danger of ovarianhyper stimulation syndrome (OHSS), which occurred if follicular induction is very strong. Along withmultifollicular growth, COS is also resulting in increased serum concentration of estradiol (E2) that inturn may has effect on the receptivity of the endometrium .The high serum E2 concentration through COSmay resulting either with an increased chance of pregnancy or an impaired reproductive score secondary tochange in endometrial receptivity. Aim of the study: to assess the impact of thickness of the endometriumat the day of hCG administration on the winning of intracytoplasmic sperm injection (ICSI) cycles. Patientsand method: A retrospective study in which 235 women who were undergo one time of ICSI cycle wereevaluated in this retrospective study, All patients were treated with gonadotrophin agonist either short orlong protocol. The patients were according to endometrial thickness they were categorized into three groupsI (<7mm), II (7-14mm), and group III (>14mm). Results: the rate of clinical pregnancy was increased ingroup II (7-14mm) than other two groups depending on endometrial thickness measurement.Conclusion: endometrial thickness 7-14mm is associated with higher rate of clinical pregnancy
Effects of Dance and Movement Therapy (DMT) versus Progressive Muscle Relaxation(PMR) on Depression among Elderly Residing in Selected Old Age Homes of Haryana: A Quasi Experimental Study Prakash Jha1 , Srinivasan.P2 , Uma J Deaver3 , Jyoti Sarin4
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.12310

Abstract

Depression is a universal health related problem which is increasing the life expectancy worldwide associatedwith morbidity and disability among elderly people. Elderly age group is a controversial issue as it is a naturalprocess which presents a unique challenge for every individual in society. The objectives of the study wereto assess and compare depression among elderly before and after administration of dance and movementtherapy and progressive muscle relaxation, to determine the relationship between depression and to find outthe association of depression with selected variables. Quantitative research approach, quasi experimentalnon equivalent control group pretest post test design was used to collect the data. Sixty participants (30DMT group, 30 PMR group) were enrolled for the study those who fulfilled the inclusion criteria by usingpurposive sampling technique. Homogeneity was checked by enrolling the participants. Data was collectedby using Geriatric Depression Scale (GDS) for assessing depression by interview technique. Analysis wasdone by applying non parametric test after K-S test to check normality of data. Thus findings of the studyshowed effectiveness of dance and movement therapy and progressive muscle relaxation on depression asthe calculated Friedman test Chi square value (DMT ?2 =51.44, p=0.00 and PMR ?2 =52.91, p=0.00) wassignificant at 0.05 in both groups. There was no any significant difference between DMT and PMR groupsin terms of depression. Depression among elderly was found to be statistically significant with duration ofstay in old age homes and history of chronic illness i.e (?=5.764, p=0.05) and (?=49.00, p=0.02) in DMTgroup, and depression among elderly was found to be statistically significant with history of chronic illnessi.e (?=49.00, p=0.04) in PMR group. Conclusion: Dance and movement therapy and Progressive musclerelaxation was effective in reducing depression among elderly as there was significant difference within thegroup.
Assess the Caregiver’s Knowledge on the Adverse Effect of Antipsychotics in the Selected Psychiatric unit of South India Joyce Fernandes1 , Sukesh Shetty2 , Nalini.M3
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.12311

Abstract

Background of the study: Antipsychotic drugs are chemicals that influence the brain and nervous systemin various ways, and they are frequently used in the practice of psychiatry to treat a broad range of mentaland emotional illness. The use of antipsychotics has reduced the number of patients hospitalized for mentalillness up to 50 % in the United States. Researchers worldwide have compared various family interventionsto enhance caregiver’s knowledge of antipsychotics, its side effects and prevent relapse, which concludedthat Psycho educational interventions are more effective in increasing knowledge and reducing stress amongthe caregivers. Psycho educational intervention is a systematic approach based on patients and family needs.The psycho education mainly emphasizes improving patient and family knowledge about the disease,coping with illness, and managing the adverse drug effects of psychotic drugs. The study aimed to assess thecaregiver’s level of knowledge on the adverse effects of antipsychotics and its association with the selecteddemographic variablesMethods: A descriptive survey design was used in this study with the one hundred study participantsselected using a purposive sampling technique and visiting the tertiary hospital of Mangaluru, south India.A Self-structured knowledge questionnaire was administered to the study participants.Results: The caregiver’s knowledge of the adverse effects of antipsychotics were assessed using descriptivestatistics. The results highlighted that more than half of the caregivers (67%) had inadequate knowledge ofthe adverse effects and management of antipsychotics, while 33% of them had adequate knowledge.
The Analysis Effect Prenatal Yoga and the Expression gen MRHR-CRHR1 and mRNA FKBP5 with Real Time-PCR Ruqaiyah1,2, Nusratuddin Abdullah3 , Mochammad Hatta4 , Syarfianty Arifuddin5 , Saidah Syamsuddin5 ,
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.12312

Abstract

Background: Stress triggers the release of corticotrophic release factor (CRF) from the hypothalamus whichin turn stimulates the anterior pituitary to release adrenocorticotrophic hormone (ACTH).Methods: The design of this study is a quasi-experimental approach / quasi experimental and one groupdesign pre and post test design with group control. The sample in this study amounted to 24 respondentsResults: Based on the results of the study showed that the sample LA24 (7,935) was the highest sample foldfold change and the lowest in the sample LA15 (6,194). Whereas in the post test results it was found thatthe LB18 sample (10,580) was the highest sample in fold change and the lowest was in the LB15 sample(8,472).Conclusion: There is a significant relationship / correlation between CRHR1 levels and FKBP5 levels (p =0.001 <?). This is indicated by the high / strong correlation coefficient value which is 0.846. A positive valueat 0.846 indicates that there is a positive relationship or a concomitant relationship, namely the influence ofyoga exercises will result in a decrease in CRHR1 levels and will further reduce the effect of FKBP5 levelsin third trimester pregnant women.
Risk Factors Related To Mastalgia Suhad Kahdum Ali
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.12313

Abstract

Background : Breast pain becomes more complicated in many humans. Various hospitals are planning forsurgery in the initial stages. The main aim of this paper to find the various factors which cause mastalgia,this is mainly causing the abnormal conditions of the breast.Methods: The experiments conducted on 400 patients and this is collected from various surveys, for patientsolder than the age of 40 the mammography and ultrasonography (US).Results: The mean age was 44.23 ± 9.23 years. This group consists of 300 cases, the asymptomatic groupconsists of 100 persons. Due to the various reasons that are related to mastalgia (p &lt; 0.05). These are basedon their breastfeeding to the child. If it is more than 4 times or more were higher in the mastalgia group (p&lt; 0.04). The breast imaging-reporting and data system (BI-RADS 2) mammography results were associatedwith mastalgia (p &lt; 0.05). These two are more common in the mastalgia group (p &lt; 0.05) that is Fibro cystsand fibro adenomas. Based on the previous history the malignant breast disease was simultaneously higherin the mastalgia group (p &lt; 0.05).Conclusions: Life stress, high caffeine consumption, smoking, lactation frequency, and benign disorderswere factors identified to be related with mastalgia. Though a significant relation between mastalgia andmalignant breast disease was detected in our study, more studies are still necessary to investigate thisrelationship.
Oral Health Care Guidelines for Patients with Diabetes Mellitus: A Review Prasanna Kumar Rao1 , Dharnappa Poojary2 , Shailesh Kudva3, Ashok Kumar Jeppu 4 , Kavitha Ashok Kuma
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.12314

Abstract

Diabetes Mellitus [DM] is a metabolic disorder characterised by relative or obsolete insufficiency of insulinand resultant disturbances of carbohydrate metabolism. People with poorly controlled DM are at greaterrisk for dental problems. They are more likely to affect with oral infections. High and low blood sugar mayalso be able to cause many oral manifestations and some emergency situations in dental office. This articlehighlights on oral manifestations and dental considerations while treating these DM patients.
The Effect of Escherichia coli on Pro-Inflammatory Mediators Level and Kidney and Liver Function of Sepsis in Rattus novergicus Dian Samudra1,2, Sumarno3 , Sanarto Santoso3 , Aswoco A. Asmoro4 , Husnul Khotimah5 , Arif N. M. Ans
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.12315

Abstract

Sepsis is a life-threatening state of organ dysfunction caused by a deregulation of the body’s response towardsan infection. The purpose of this study was to determine the pro-inflammatory mediators’ level as well askidney and liver organ function on the Rattus novergicus sepsis model injected intraperitoneally (i.p.) withE. coli. This study used 20 male rats (Rattus novergicus, Wistar strain) which were divided into 2 groups:rats without E. coli injection and rats were i.p. with 105 CFU of E. coli. After six hours, the level of proinflammatory mediators (TNF?, Hs-CRP, PCT, and MDA), kidney function (urea, BUN, and creatinine), andliver function (SGPT, SGOT, and the total of bilirubin) were examined. The data obtained were analyzed usingT-Test. This study concluded that intraperitoneal injection of E. coli increased pro-inflammatory mediatorlevels which include TNF?, Hs-CRP, PCT, MDA level. It also increased kidney function. Interestingly, theinjection only increased bilirubin total levels in the liver but did not show improvement in the SGPT andSGOT. In summary, there was a significant increase in TNF-? pro-inflammatory mediators, procalcitonin(PCT), malondialdehyde (MDA), urea kidney function parameters and BUN among treatment groups. Thehs-CRP, creatinine, and total bilirubin experienced a significant increase.
Stress Related Temporomandibular Joint Disorders - A Comparative Study between Preclinical and Clinical Undergraduate Students of Dentistry Munazza Sharfuddin1 , Ayshwarya Muralidharan2 , Premalatha Shetty3 , Aditya Nandan4 , Animesh Jain5
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.12316

Abstract

Objective: This cross-sectional study compared the proportion and severity of stress related TMD, genderpredilection and influence of parafunctional habits in preclinical and clinical undergraduate students ofdentistry.Method: The data was collected using Fonseca’s Anamnestic index and Zung’s Self-rating Anxiety Scale.The results were analyzed as proportions and percentage. Chi square test was used. A ‘p value’ of less than0.05 was considered as significant.Results: Mild to moderate anxiety levels were seen in 6.4% females and 3.4% males .According to the FAI,48.2% females and 67.8% males did not have TMD. Mild, moderate and severe TMD were seen in 41.1%,9.2% and 1.4% of the females and 27.1%, 5.1% and 0% males respectively.Conclusion: While the proportion of stress was higher in preclinical students, TMD was higher in clinicalstudents. TMD observed in clinical students could be a manifestation of the stress they experienced in theirformer years
Deleted Suhad Kahdum Ali
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.12317

Abstract

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