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INDONESIA
Indian Journal of Forensic Medicine & Toxicology
Published by Official Organ of Indian Association of Medico-Legal Expert
ISSN : -     EISSN : -     DOI : -
Core Subject : Health,
Public Health
Arjuna Subject : Kedokteran - Epidemilogi
Articles 5,497 Documents
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Possible Protective Effects of high- versus low- dose of lutein in combination with irinotecan on Liver of Rats: Role of Oxidative Stress and Apoptosis Alaa Radhi K1 , Nada N. Al-Shawi
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 1 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i1.13767

Abstract

Objectives: The current study was designed to describe roles of oxidative stress via the measurementof malondialdehyde and total antioxidant markers, and apoptosis through the measurement of caspase 3marker, as mechanisms of liver toxicity induced by irinotecan; and to explore the possible protective effectsof high- and low- doses of lutein against irinotecan induced toxicity in the liver of rats.Methods: Thirty six (36) Sprague-Dawley rats were randomly divided into six groups: Groups ?, ratsreceived single oral daily dose of dimethyl sulfoxide (4 ml/kg); Group ?? (irinotecan-treated), receivedsingle oral daily dose of dimethyl sulfoxide (4ml/kg) for 25 days by oral gavage and subsequently receivedirinotecan (50mg/kg) on days: 5, 10, 15 (total dose=150 mg/kg) by intraperitoneal injection; Groups ???and ?V, received oral dose of lutein (6mg/kg/day) and (24mg/kg/day), respectively by oral gavage for 25successive days (lutein-treated); Groups V and V? (lutein+ irinotecan), received oral dose of lutein (6mg/kg/day) and (24mg /kg/day), respectively by oral gavage for 25 successive days, and subsequently receivedirinotecan (50mg /kg body weight) on days: 5, 10, 15 (total dose=150 mg/kg) by intraperitoneal injection.Results: Orally-administered lutein with total cumulative dose of irinotecan (Groups V and VI), resultedin significant reduction (P<0.05) of serum aspartate aminotransferase and alanine aminotransferase, andsignificant reduction (P<0.05) of malondialdehyde; but, significant elevation (P<0.05) of serum totalantioxidant capacity; and there was significant reduction in caspase 3in liver tissues homogenates comparedto the corresponding levels in the group of rats administered irinotecan (Group II).Conclusion: Results of the current finding suggested that administration of lutein may be a useful compoundthat alleviated irinotecan induced toxicity to the liver
The association between severity of dental caries and salivary immunoglobulins in asthmatic adult patients Ahmed AbdulRazzaq Hammoodi Al-Anbari,1 Maha Adel Mahmmod AL-Ani)
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 1 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i1.13768

Abstract

The salivary samples were collected adequately from 80 subjects distributed equally (40 asthmatic subjectsand 40 control subjects) of ages range between 20-60 years. This comparative survey was determining thecaries index(DMFT),Streptococcus mutans , Streptococcus sobrinus ,salivary IgA and IgE. So this studyhave shown highly significant difference P ? (0.01) found in effect of age on salivary IgA in control adultsubjects and non-significant difference (P > 0.05) displayed in influence of age on salivary IgA. So thiscomparative investigation have demonstrated that non-significant difference (P > 0.05) found in influenceof age on salivary IgE to both groups of study. However, the correlation between age and salivary IgE is aweak negative relationship.
Phenotypic and molecular characteristics of biofilm and other virulence genes in E. coli and K. pneumoniae isolates from healthy dairy cow, human and environmental sources Ali A. Kadhum1 , Mohammed H. Khudor2
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 1 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i1.13769

Abstract

Escherichia coli and Klebsiella pneumoniae for ones role in opportunistic infections and pathogenic methodsin veterinary and human medicine, including the formation of biofilms. 33 E.coli and 8 K. pneumoniaeisolates of these micro-organisms isolated from cow’s milk, stools and utensils. Identification were done bybiochemical reaction and confirmed by Polymerase Chain (PCR). These isolates exhibit biofilms formation,as strong, moderate, weak capacities. The expression of the fimA gene. The percentage (84.8%)28/33 ofE.coli was able to produce biofilm while (100%)8/8 in K. pneumoniae The virulence factors of all bacterialisolates were also studied to determine hylA and bla-CTX-M genes in E.coli and, magA and bla-CTX-Mgenes in K. pneumoniae were results presence extended spectrum ?- lactamases (ESBLs). bla-CTX-M genein E. coli and K. pneumoniae (78.7% , 87.5%) It also emerged that not all isolates carry other virulence genesfor this study
The effect of Exercises By Pressing -Style to Developing A Man-to-Man Defense For Young Football Players Qasim Muhammad Ali Hazim1 Ahmed Abdulameer Hamzah2
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 1 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i1.13770

Abstract

The importance of the research is that it is a research attempt that is concerned with consolidating the ideaof a pressing play style in the reality of Iraqi clubs and teams training through this defensive method toachieve the desired goal, as well as experimenting with the use of defensive exercises characterized by rapidapplication and high accuracy together, and to know the extent of the impact of exercises in a pressing styleof play in developing defense man to man for young football players in a step aimed at strengthening thesports field with practical experiments and service to researchers in the sports field. The research objectivesto prepare pressing play style exercises to develop defense, man to man, for young football players. Toidentify the effect of exercises in a pressing play style in developing defense, man to man for young footballplayers. The researchers used the experimental method to design the two equivalent groups (experimentaland control) with a pre and post- test that is consistent with the nature of the research problem. The researchsample was chosen by a simple random method (lottery), where the experimental group was represented bythe Al Shuohda youth sports club, whose number was (22) players, and the control group was represented inthe Nahrain youth sports club, whose number is (21), (10) players were chosen from each group, experimentaland control group by the deliberate method, and the research variables included the defense man to man(Close defense - flexible defense - cutting and acquisition - cutting and farthest). The researchers usedstatistical methods (mean, standard deviation, coefficient of torsion, Levin’s coefficient, t-test for correlatedand non-correlated samples), and after presenting, analyzing and discussing the results, the researchersreached the following conclusions: pressing play style exercises developed man-to-man defense with twotypes of close defense and flexible defense for the experimental group under study. pressing play developedcutting, possession, cutting and farthest.
Assessment of Mothers' Knowledge about Febrile Convulsions of Children at Ibn- Albalady Hospital in Baghdad City Ali Obaed Shneshil
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 1 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i1.13771

Abstract

Background: In terms of occurrence, about of children in the age group of one to five years have at leastone episode of febrile convulsion. These, have recurrent seizures and many get admitted to the hospital.Aims: This study was conducted to assess the level of mother's knowledge about Febrile ConvulsionsMethodology: A descriptive study design has been conducted with pediatric emergency unit at the IbnAlbalady Hospital in Baghdad City during the period from the 3rd March 2020 up to the 13th 2020. Apurposive non probability sample of (100) mother were selected from emergency pediatric unit. Out of thewomen questioned, febrile convulsion was reported by 100 mothers. Table (2) summarizes that the mothersknowledge items concerning child with febrile convulsion. In general, their knowledge were poor to fairin all items, and they are accounted for 2(18.1%), 9(81.9%) respectively, and overall mothers knowledgeabout febrile convulsion were fair. The results illustrate that (48%) of the study sample represent fairknowledge, (39%) were having poor information and (13%) were having good information about childwith febrile convulsion at emergency ward of Ibn- Albalady hospital. The data were collected by usingconstructed questionnaire, which consisted of 11 items self-administrated method used and filled by usingthe questionnaire. Been described of data analyzed through using of two statistical approaches. Descriptivestatistical analysis and inferential statistical analysis.Results: The study results revealed that (48%) of the mothers under study were having fair knowledge.Mothers' knowledge regarding febrile seizures was non-significantly associated with positive history offebrile seizures, urban residence, higher parental education, and working mothers.Conclusions: Generally, mothers’ knowledge regarding their children with febrile convulsions was poor tofair.
IS There an Impact of PAI-1 on the Thrombotic Episode in Iraqi Obese Patients with Corona Virus -19 Elham Abed Mahdi
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 1 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i1.13772

Abstract

Objective: firstly To assess the incidence of Corona Virus -19 covid-19 as risk factors in obese individualsleading to thrombotic episode, and secondly to compare the effects Plasminogen activator inhibitor-1 (PAI-1)on the occurrence of this thrombotic status in obese and normal body weight individuals. The pathogenesisof Coronavirus disease 2019 (COVID-19) is gradually demonstrated and explained around the world A highand a great number of thrombotic episodes are reported, in present study can be consider the COVID-19 asa prothrombotic disease.Design and Methods: The experiments comparing the PAI-1 in 90 obese and 30 normal body weightparticipants aged 32-62 years. The obese patients subdivided to three groups: first group consisted from 30over weight individuals and the second group comprised from 30 obese patients, while third group consistedfrom 30 morbid obesity patients. All participants underwent to the medical examinations to make sure theywere infected with covid-19. The activity of PAI-1and tissue plasminogen activator (t-PA) was determinedby applied ELISA method by certain kit in all study groups individuals.Results: Three study groups (overweight, obese, and morbid obesity) elicited significant (p< 0.05) elevationin metabolic characteristics such as fasting blood glucose (FBG), fasting insulin and lipids variables, as wellas increasing in insulin resistance (HOMA-IR) and D-dimer fractions, in addition to there were significantaugmentation in PAI-1 and t-PA in three study groups when comparing with those of normal or healthy bodyweightThe present results show a positive relationship between PAI-1 and body mass index, t-PA, D-dimer andmetabolic characteristics which include fasting blood glucose, fasting insulin and lipids fractions, alsoHOMA-IR.
Molecular, Biochemical, and Phenotypic Identification of Phenol and Cresol Degrading Acinetobacter baumanni Strain Selected from Al-Rumaila Oil Well Noor Mohammad Ali1 , Aamal Ghazi Mahdi Al-Saadi1
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 1 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i1.13773

Abstract

Background: phenol and cresol are dangerous compounds that have harmful effects on aquatic life, plantsand, many other organisms. Therefore, it is necessary to effectively eliminate these compounds to protectthe environment.Aim: The aim of this study is to select and characterizebacterial strain(s) from oil contaminated soils andtesting its ability for biodegrading phenol and cresol.Methods: Biochemical tests were performed in addition to morphological and molecular detection through16S rRNA analysis to identify the selected strain after growing on Mineral salts medium (MM) containingphenol or cresol . The residual concentration of phenol and cresol was analyzed over the time period bymeans of the 4-aminoantipyrine assay .Results: the selected strain was identified as Acinetobacter baumannii strain HILLA-1, and it was able toremove 100% of the phenol at all the used concentrationsafter 48 h. This strain was also able to degrade 100%of cresol at concentrations (25,50,75,100,200 ppm /L) and99.37%,88.69%,and 94.73% at concentrations(300,400,500 ppm /L) respectivelyafter 48 h.Conclusion: The selected and identified Acinetobacter baumannii strain HILLA-1 can provide a putativesource for bioremediation of phenol and cresol contaminated environments.
Evaluating Growth Charts Use among Children Less Than Five Years of Age at Primary Health Care Centers in Al-Hillah City Muna Abdulwahab Khaleel
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 1 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i1.13774

Abstract

The study was conducted at two primary health care centers in Al Hilla city which covered Al Gameyahprimary health care center and Al Kawthar primary health care center for the purpose of evaluating the useof growth chart and to determine mothers understanding toward the meaning of the weight chart in terms ofgrowth. All registered children aged 0-5 years who were living in areas served by the above two mentionedprimary health centers were included. The following results may be drawn on the objectives of the study.The proportion of registered children who possessed a chart was very high (99.8%). The proportion ofregistered children who acquired a chart at birth was high too (99.6%). It is of interest to find that the dateof birth of (99.6%) of children was registered and the weight at birth of (99.2%) of them was known too. Itwas found that only (90%) of study population had their weight charted on the curve of growth charts. Thestudy showed that no children of both sexes were attending regularly to have their weight charted in mostmonths of the year. The study generally depicted that the level of immunization of the children in study areawas remarkable and high.
Complications of Kalazar among Children in Hilla-city Ibtesam Khalid Kamil
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 1 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i1.13775

Abstract

Objective: This study aimed to detect the types of complications of children suffering from kalazar; also toidentify the reason of these complications.Methodology: A descriptive study carried out from Feb15th to June 15th of the academic year 2017. Thesample consisted (109) children from general maternal and children hospital in Hilla/Babylon. The studydesigned and data was collected using structural questionnaire which was prepared by consulting panelresearch expertise, also by assessment approach and interview was done with parents of children. Thecollected data were analyzed through descriptive statistics by frecuency and percentage.Results: The results of the present study indicated that most of the children age were (13-18) yrs.(40.4%);male gender more involved (67%) and (27%) were from Mesaib city. The education level of parents werewithin secondary school, mothers (52%) fathers (43%). The income of affected children families involvedin the study were (51%) poor, which isn’t enough to maintain healthy well being status and medicalrequirements. Complications revealed that children suffers from bleeding tendancy (13.5%) sever animeawere (20%) hepato spleenomegaly were (14.0%) , finally death occurs because of septicemia (37%).Conclusion: Complications accurs because of poor and inappropriate medical diagnosis, also infectivemedical treatment during hospitalization and lake of medical follow up to children suffering from kalazar bythe health team after hospital discharge.
Assessment of Diabetes Patient Adherence to Dietary Recommendation in Diabetics Center in Al-Najaf city Iman Qasim Kteo Al-hussein 1 , Zahraa Abdull Abbass Taher Al- Khafajy 1 , Haider Mohammed Haloob ALA
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 1 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i1.13776

Abstract

Objective: This study aimed to assess of diabetes patient adherence to dietary recommendation in Diabeticscenter in Al-Najaf city and to find out the relationship between the diabetic patient adherence to dietaryrecommendation and their demographic and clinical data. Methodology: Descriptive analytic design wascarried out to assess of diabetics patient adherence to dietary recommendation in Al-Najaf City/ HealthDirectorate of Al-Najaf Al-Ashraf / Al-Sadder Medical City / Al-Najaf Center for Diabetes and Endocrine.The study was carried out from February 1st, 2018 up to March 28th, 2018. A non-probability (accidental)sampling technique was used consisting of (100) female and male those who visit Al-Najaf Center forDiabetes and Endocrine. Data collected through using of a well-designed questionnaire consist of threeparts: Part I: Socio-demographic Characteristics, Part II: Clinical Data: consists of (6) items and Part 111:Patient adherence to dietary recommendation. This part of the questionnaire consists of (16) items.Conclusion: It is concluded that the Majority of the stay sample have fair adherence to diabetics dietaryrecommendations.Recommendation: Based on study conclusion, its need for a good relationship between the patient andhealth- care provider in order to provide more understanding and knowledge about the disease and its nonmedical management and diabetic’s patients need dietary recommendations with means of education, suchas published materials with regard to dietary regimen.

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