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INDONESIA
Indian Journal of Forensic Medicine & Toxicology
Published by Official Organ of Indian Association of Medico-Legal Expert
ISSN : -     EISSN : -     DOI : -
Core Subject : Health,
Public Health
Arjuna Subject : Kedokteran - Epidemilogi
Articles 5,497 Documents
 450   451   452   453   454 
Role of PRGF (Plasma Rich in Growth Factors) in Periodontal Regeneration Mohit Das; Abhaya Chandra Das; Sourav Panda; Manoj Kumar; Rinkee Mohanty; Gatha Mohanty
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14979

Abstract

Platelet-rich-growth-factors (PRGF), a modification of fibrin glue made from autologous blood, is beingused to deliver growth factors in high concentration to sites requiring osseous grafting. Growth factorsreleased from the platelets include platelet-derived growth factor(PDGF), transforming growth factor-beta(TGF-ß), platelet-derived epidermal growth factor (PDGF), platelet-derived angiogenesis factor, insulin-likegrowth factor 1(IGF1), and platelet factor 4. These factors signal the local mesenchymal and epithelial cellsto migrate, divide, and increase collagen and matrix synthesis. Anitua et al in 2001 introduced the concept ofPRGF and since then it has been used for a variety of purposes in the field of dentistry and oral implantologyfor proper wound healing and regeneration of periodontal tissues. This review aims to give a brief ideaabout the various uses of PRGF and the possibility of utilization in the future taking into consideration manystudies that have been done. The main advantage of using PRGF is that it lacks the leukocyte content thuspreventing damage to the tissues during healing due to the acid hydrolases and proteases released from theneutrophils. It has been previously used for treating intrabony defects, to increase the implant-bone contactarea, for recession coverage etc. In other fields of medicine, it has been used to cure osteoarthritis, to treatchronic ulcers as well. Therefore, PRGF is a very effective blood concentrate with a high concentration ofgrowth factors and its use should be increased in the clinical practice.
A Study to Evaluate the Analgesic Efficacy of Transdermal Diclofenac Sodium Patch in Minor Oral and Maxillofacial Procedure Pratikshya Kothai; Santosh Kumar Subudhi; Sthitaprajna Lenka; Subrat Kumar Padhiary; Satchidananda Meher
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14980

Abstract

Aims and Objectives: The aim and objectives of this study are to evaluate and determine the efficacy oftransdermal diclofenac patch in control of pain following Routine Extractions, Transalveolar extractions,Soft tissue biopsies, to evaluate any adverse reactions following the usage of the transdermal patch and torelate its efficacy to the gender, pre-surgical condition of the patient and time taken for the procedure.Materials and methods: A clinical study was done in the patients coming to the Oral and Maxillofacialsurgery department, Institute of Dental Sciences, SOA University. A total of 537 patients were selected fromour patients in Oral and Maxillofacial Surgery department who underwent routine extractions, Transalveolarextractions, Soft tissue biopsies etc.Results: 500 patients who underwent minor surgical procedures under local anaesthesia with adrenaline.The patient has then prescribed a diclofenac patch for analgesic purpose and the efficacy and tolerability ofthe patch was evaluated. Using SPSS software, statistical analysis was done. All the patients were evaluatedwith VAS scale and Wong baker scale on 1st day, 2nd day and 3rd day. The mean age of the patient is 28.2years and the mean value for the time taken for the procedure is 14.4 min.Conclusion: Transdermal patch can be effectively used for analgesic effect following minor oral surgicalprocedures of lesser duration. It is effective for the management of mild to moderate pain relief as it hasproved to be a good option as an analgesic especially in patients with gastric problems and for bettercompliance.
Biosensors Used in Dentistry: A Review Nitish Kanta Mishra; Ramesh Nagarajappa; Debasruti Naik
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14981

Abstract

A bio-sensor is composed of six elements which include bio-receptor, transfusion element, chemically activeinterface, signal amplifier, signal processor and display. The analyze binds to the immobilized biologicalmaterial and forms a product. The product linked change is then converted by the transducer into electricsignals which can be amplified and measured. Oral fluid bio-sensors have the advantages of easy accessibilityand noninvasive sample collection, making them a novel method in disease diagnostics. However, itslimitations such as less sensitivity and specificity are overcome by the advent of new technologies such asmicrofluidics and nanofluidics. This review article discusses the concepts and applications of biosensors inthe field of dentistry.
Control Strategies and Behavioural Changes in the Elimination of COVID-19 from India Srishti S. Chatterjee; Rupsita Sahu; Ramesh Nagarajappa; Debasruti Naik
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14982

Abstract

The massive spread of the novel coronavirus and its associated disease COVID 19 as a pandemic aroundthe world has gripped the international community, crippled healthcare systems and raised enormous publichealth concerns. The universe attempts to restrict the virus until now have yielded little fruit because of thezoonotic transmission ability of the virus. Countless healthcare professionals have already become infectedwith the disease and dentists are considered to be especially vulnerable. This article reviews the origins ofthe virus, its modes of transmission, symptoms and the recommendation provided to the dentists to diagnoseand manage a patient confirmed/ suspected of COVID 19 in the dental office.
A Comparative Study of the Efficacy of Methylprednisolone Administration Route on Postoperative Sequelae Following Impacted Third Molar Extraction Bijayalaxmi Panigrahi; Santosh Kumar Subudhi
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14983

Abstract

Background: Surgery on the lower-impacted third molar typically includes injury to the heavily vascularizedloose connective tissue due to its anatomical location, leading to inflammatory sequelae during the immediatepost-operative stage, including postoperative pain, oedema and trismus.Aims: This prospective, randomized, comparative clinical study was conducted in 30 patients to assess pain,oedema and trismus in patients undergoing surgical removal of impacted third molars.Method: The study sample involves 30 patients, randomly categorized into 3 groups: group 1 (control;no steroids), group 2 (Intra-Muscular injection in Masseter muscle), group 3 (oral tablets). Patient agedbetween 18 and 30, with a similar anatomical position, and similar surgical difficulty, no allergies, withoutany systemic diseases are included. Syndromic patients, patients with periapical pathologies were excludedfrom the study. A single surgeon was working on all patients using a standard technique. On the 2ndand 7th postoperative day, linear oedema and maximal mouth opening were evaluated for both routes ofmethylprednisolone administration and compared.Results: We observed a higher range of mouth opening found in masseter injection group relative to theoral tablet group on Day 2 & 7, for the steroid treatment groups. On postoperative days 2 and 7, the overallincrease in the tragus-commissure, canthus-gonion and tragus-pogonion lines, for control & oral tabletgroups were identical and higher than the masseter injection group.Conclusion: Comparison to the control group following lower third molar surgery, intramassetric injectionprovided improved outcomes than tablet form in limiting oedema and trismus
Acrocephalosyndactyly Syndrome: A Rare Case Report Satya Ranjan Misra
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14984

Abstract

Acrocephalosyndactyly or Apert syndrome is a rare disorder in which the fingers and toes are fused,giving the appearance of webbed hand and feet. Also, there is craniosynostosis, leading to severe mid-facehypoplasia and characteristic facial deformities. Here there is a genetic mutation in the fibroblast growthfactor receptor 2 (FGFR2) gene with autosomal dominant inheritance. A case of an 8-year-old male child isreported here with frontal bossing, acrocephaly, prominent ocular hypertelorism with divergent strabismus,saddle-shaped nose, mid-face hypoplasia, crowded anterior teeth, sparse hair and severe bilateral syndactylyof the feet and hands.
Skeletal Bimaxillary Protrusion: Combined Surgical and Orthodontic Approach – A Case Report Subrat Kumar Padhiary; Kanhu Charan Sahu; Gunjan Srivastava; Harsh Mohan Pathak
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14985

Abstract

Bimaxillary protrusion is one of the commonly seen skeletal deformity in Indian population. This skeletalcondition is typically characterized by proclined and protruding anterior teeth with everted lips. If thiscondition is associated with macroglossia or any parafunctional habits like tongue thrusting or thumbsucking, an anterior open bite is often found. Minor discrepancies can be managed by orthodontic treatmentalone by extracting all first premolars and retracting the anterior segment. But in severe skeletal cases,orthognathic surgery along with pre-and post-surgical orthodontics is the best option to get the ideal result.This article describes the case of a female patient with bimaxillary protrusion. The patient had a convexprofile, anterior open bite, and incompetent lips. Chin had a relative deficiency with hyperactive mentalismuscle. On patients’ consent and willingness for a shorter course of the treatment period, surgery firstapproach was planned. Within seven months of the total treatment period, a remarkable change in facialprofile and a pleasing anterior occlusion was achieved.
Biomimetic Materials in Restorative Dentistry and Endodontics – A Review Monika Mohanty; Shashirekha Govind; Rini Behera
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14986

Abstract

In 1950, while researching the nerves in a squid, Otto Schmitt coined the word “Biomimetics” It meansimitating life, literally. To seek to mimic or reproduce it artificially to preserve the same esthetics or work is thestudy of natural structural processes. Since tooth structure has no natural means for restoration, biomimeticmethods can be implied to restore the teeth mechanically to its normal function and esthetics. There are twothings of biomimetic dentistry. First, the damaged or absent dental tissue is replaced, leading to completerestoration to the tooth of function and aesthetics. And the substance used will regenerate the damaged dentaltissue, replicate and imitate it. The bio-compliant and Physico-chemical products of biomimetic materialhave the benefits of improved biocompatibility, sealing ability, high strength, antibacterial properties andare used to preserve long term esthetic and restoring techniques. Recent biomimetic technologies haveestablished the potential to transcend various considerable drawbacks of technologies of a previous age. Thisstudy would seek to provide a clearer explanation for biomimetic materials ‘relative role in the sense of pastand current dental materials.
Dental Caries Vaccines –An Emerging Viable Treatment for Modern Dentists Sudipta Sahu; Kajal Kiran Sahoo; Debashruti Naik; Sharmistha Mohanty
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14987

Abstract

Dental caries is an irreversible microbial disease of the calcified tissues of the teeth. It is a bacterial driven,generally chronic, site-specific, the multifunctional dynamic disease process that results when the PH dropresults in net mineral loss over time. It is one of the most prevalent diseases affecting mankind. Cariogenicbacteria enter the dental biofilm early in life and subsequently invade the host tissue during favourableenvironment condition, to cause the disease. Many studies and researches show that this disease processcan be interrupted. This article will give a clear idea of the method by which the host defence system can bearoused to combat dental caries caused by the crucial antigen related to Streptococcus mutans. Analyzingthe fact that more effective public dental health care measures are needed to combat this dental caries, thisarticle critically evaluates the recent signs of progress in the development of mucosal adjuvants, deliverysystems for the dental vaccine, and also limitations of caries immunization.
Platelet Rich Fibrin( PRF )-A Novel Generation of Regeneration in Endodontics: A Review Manali Nath; Shashirekha Govind; Siba Prasad Jena
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14988

Abstract

In the field of regenerative medicine, PRP/PRF whichwas will be is used as a surgical adjuvant becamethe new glorified approach. For the Regenerative endodontic treatment based on the tissue engineeringconcept, creating a favourable environment free of pathogens, for preservation and migration of stem cells,pathogen eradication, stem cell preservation, presence of scaffold facilitating spatial orientation and signalmolecules released by cells is of utmost importance. In tooth revascularisation and revitalization, successfulapplication of platelet concentrates as scaffolds have been reported. Being autologous, comprising of highgrowth factor concentrates and relatively hassle-free preparation in dental setup, platelet concentrates arepreferred. The advancement in the regenerative endodontics field, with the introduction of the differentgeneration of platelet concentrates, is a breakthrough.

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