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INDONESIA
Indian Journal of Forensic Medicine & Toxicology
Published by Official Organ of Indian Association of Medico-Legal Expert
ISSN : -     EISSN : -     DOI : -
Core Subject : Health,
Public Health
Arjuna Subject : Kedokteran - Epidemilogi
Articles 5,497 Documents
 58   59   60   61   62 
Effect of CaCl 2 Crosslink Solution Concentration on the Characteristics of Gelatin Alginate Microspheres Rizka Safitri1, Tutiek Purwanti1, Widji Soeratri1
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.3216

Abstract

Alginate as a constituent of microspheres matrix has a weakness, namely the lack of ability to slow the release of drugs from the system, causing the effects of drug therapy to the body to be less than optimal. To obtain preparations with slowed release, sodium alginate needs to be combined with other polymers such as gelatin. This study aims to determine the effect of the concentration of CaCl 2 connection solution on the characteristics of alginate-gelatin microspheres. In this study, alginate-gelatin microspheres were prepared using ionotropic gelation aerosolization techniques. Three formulas were made, each of which was replicated three times. F1 with CaCl concentration2 0.5 M, F2 with CaCl concentration2 1.0 M, F3 with a concentration of 1.5 M. The three formulas were made in the ratio of alginate-gelatin (1.5: 1)% and a crosslinking time of 1.5 hours. Evaluation of the characteristics of microspheres includes yield percentage, organoleptic, moisture content, morphology of microspheres, size and size distribution of microspheres, and swelling index. The data of this study were analyzed using one way ANNOVA. The results reveals a loss of specific uptake of the COO-manuronate alginate group and the occurrence of wave number shifts as well as an increase in the absorption intensity of the C = O group. Organoleptic examination results of alginate-gelatinin microspheres showed that microspheres of the three formulas had the same organoleptic, and formed spherical microspheres. On the inspection of swelling index, it was found that F1 and F2 reached the peak of swelling at 2 o’clock, while F3 reaches the peak of swelling at 3 o’clock. The greater the level of CaCl2, then the average diameter of microspheres will also increase, while the swelling index will decrease with increasing levels of CaCl2. In the results of moisture content examination, there is no difference in different CaCl 2.
Association of Adiponectin and IgE levels with occurrence of asthma in Babylon Province Ruwaida Wahab Salman AL-Jebory
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.3217

Abstract

ackground : Asthma is a health condition that affects breathing in people. Breathing comfortably is not something most of us need to think about. But if you have asthma, there are times when you have difficulty breathing.The main objectives in the current study are:Determine the role of adiponectin, a hormone that acts as an anti-inflammatory, In addition determine the concentration of immunoglobulin E (IgE) In asthma patients. Method: This study included two groups:Group 1: 80 Patients with asthma were divided into two parts (40 samples obese and 40 samples non-obese).Group 2: 80Group of healthy subjects with no history or clinical evidence of asthma. samples were divided into two parts (40 samples were obese and 40 were not obese). Asthma was diagnosed through a pulmonary function test (PFT) and then invited to a private clinic and measured nitric oxide gas (FeNO) to confirm the diagnosis.Enzyme-linked immunosorbent assay(ELISA ) technique was used to determine the concentration of adiponectin and IgE in serum. Results: The present study demonstrated the increase of adiponectin level with asthmatic patients compared with the control group and showed significant difference between non-obese patients group and non-obese healthy group. Conclusion: Adiponectin related with obesity play crucial role in asthma development and inverse relationship between IgE and adiponectin
Comparison of the Total amount of Macrophages on Full Thickness Wound Bed in The Use of Tulle, Freeze-Dried Amnion, and Microbial Cellulose Saktrio Darmono S.1, Beta Subakti Nata’atmadja1, David Sontani Perdanakusuma1
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.3218

Abstract

Background: The wound is the most frequent problems faced by plastic surgeon. Many factors can affect the wound healing process. Macrophages are as one indicator of wound healing which present in the wound within 24-48 hours after injury. Currently, there is a variety of wound dressing available which can increase the levels of macrophages in the wound healing process according to previous research. Objectives: To compare the total amount of macrophages on full thickness wound bed in the use of tulle, freezedried amnion, and microbial cellulose on the second day. Material and Method: The study design was experimental, post-test only group design using 21 male rats Rattus norvegicus. The wound was closed with tulle, amnion, and microbial cellulose which was evaluated on the second day. The samples wounds were fixed by 10% formalin solution then examination of samples was conducted by Wright-Giemsa staining routine/Hemato-eosin under a microscope. Results: Macrophages obtained at a given tulle ranges between 41-96, freeze-dried amniotic at 51-142, and the microbial cellulose at 55-96. In other hand, the mean number of macrophages in the wound by the microbial cellulose at 77.4; its 1.3 times higher than the given tulle at 59; meanwhile its 0.9 times lower than the freeze-dried amniotic given by 83. Conclusions: There were no differences in the increase number of macrophages in the wound bed by the use of tulle, freeze-dried amnion and microbial cellulose on the second day.
Evaluation of Women’s Perception toward Childbirth Experience after Utilization of Pain Management Practices at Al -Elwyia Maternity Teaching Hospital Sarab Nasr Fadhil1, Rabea Mohsen Ali2
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.3219

Abstract

Objectives: To evaluate the women’s perception with Childbirth Experience after utilization Pain Management Practices. Methodology: A quasi-experimental study conducted on non-probability of (30) women whom admitted to Al-Elwyia Maternity Teaching Hospital suffering from labor pain for the period of (4th July 2018 through 24th October 2018). Descriptive& Inferential statistical analyses were used to analyze the data. Results: show that the highest percentages of non- pharmacological methods used was frankincense oil, and related to women perception of labor pain they are assessed high as general, and they are accounted 24(96.0%). Conclusions: The study concluded that there are a positive evaluation observed regarding women’s perception with childbirth experience after utilization pain management practices. Recommendations: The study recommended developing structured training program and clinical practice guideline of non-pharmacological pain management methods during labor and childbirth should be made available in English and Arabic which contains information about the proper use of non-pharmacological pain management methods and its advantages to midwives working in delivery room.
Mention the Treatment of Anger in Hospitalized Patients in the CCU department of Social Security Hospitals of Golestan Province Soudabeh Aloustani1, Leila Mamashli2, Adeleh Sadeghloo3, Mohammad Reza rajablou4
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.3220

Abstract

Background: Anger is one of the worst negative predictions in cardiac patients. Therefore, this study aimed to cure the anger of patients admitted to the Cardiac Care Unit. Method: This quasi-experimental study was performed on 60 cardiac patients admitted to the heart care unit in a non-randomized sampling method in two groups (n = 30) and control (n = 30). In the test group, four to five times a day, the patient whispered to Allah Akbar or the prayers of Hazrat Zahra. In the control group, routine care was performed. The instrument for collecting information was anger questionnaire which was completed by self-report method before and after the intervention by the patients. The results were analyzed by inferential statistics (T-test, T-test and Independent T-test). Result: Paired t-test showed a significant difference in the test group before and after the intervention (P <0.01). But in the control group there was no significant difference (P = 0.92). Independent t-test before intervention in the control and experimental group did not show a significant difference (P = 0.22), but this test showed a significant difference after the intervention (P = 0.006) Conclusion: Considering the effectiveness of the therapeutic approach to reducing the rate of anger in heart patients, this non-therapeutic method can be used to reduce stress and psychological disturbances in patients and to increase the compatibility and relaxation of patients.
The Comparison of Social Support Against the Life Quality of The Spinal Cord Injury Under Stress Soudabeh Aloustani1, Karvan Bekmaz2, Adeleh Sadeghloo3, Hamid Hojjati1
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.3221

Abstract

Introduction: The stress of war has caused severe problems for the individual and family. Spouses of veterans are gradually involved in family erosion. Lack of social protection and social dysfunction decreased life satisfaction and reduce intimacy between partners. Purpose: this study has been done in the purpose of comparing social support against the veteran’s life who are under stress. Method: This cross-sectional study was done on 79 posttraumatic stress disorder veteran wives and it was also done on 79 ordinary wives through convenience sampling. The instrument to collect the required information was the quality of life questionnaire which contained 36 SF questions and Medical Outcomes Study Social Support Survey (MOS-SS).and the needed information was collected by self-reported method. Results: Veteran wives social support with the mean and the standard deviation was 19.3±5.1 while it was 31.1±3.7 versus the ordinary wives and this difference was significant (Pless than 0.01).It showed the veteran wives quality of life with the mean and standard deviation of 46.3±.088 while it showed 66.9±8.5the mean and standard deviation for the ordinary wives and it showed the significant difference (Pless than 0.01). Conclusions: the obtained result showed that the quality of life related to the health and social support in veteran wives is lower in compare with the ordinary wives with the same situation, therefore educational, treatment and supporting and promoting plans for this group is necessary
Risk Factors Related To Mastalgia Suhad Kahdum Ali
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.3222

Abstract

Background: Breast pain becomes more complicated in many humans. Various hospitals are planning for surgery in the initial stages. The main aim of this paper to find the various factors which cause mastalgia, this is mainly causing the abnormal conditions of the breast. Method : The experiments conducted on 400 patients and this is collected from various surveys, for patients older than the age of 40 the mammography and ultrasonography (US). Results : The mean age was 44.23 ± 9.23 years. This group consists of 300 cases, the asymptomatic group consists of 100 persons. Due to the various reasons that are related to mastalgia (p < 0.05). These are based on their breastfeeding to the child. If it is more than 4 times or more were higher in the mastalgia group (p < 0.04). The breast imaging-reporting and data system (BI-RADS 2) mammography results were associated with mastalgia (p < 0.05). These two are more common in the mastalgia group (p < 0.05) that is Fibro cysts and fibro adenomas. Based on the previous history the malignant breast disease was simultaneously higher in the mastalgia group (p < 0.05). Conclusions : Life stress, high caffeine consumption, smoking, lactation frequency, and benign disorders were factors identified to be related with mastalgia. Though a significant relation between mastalgia and malignant breast disease was detected in our study, more studies are still necessary to investigate this relationship.
Genetics Risk Factors and Progression of Renal Failure Suhayr A.Alqaysi
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.3223

Abstract

Objective: “MYH9 gene” is “expressed” in “kidney, platelets and liver and in lesser amounts in the thymus, spleen, and intestine”, its responsible for encoding a protein called “non muscle myosin heavy chain”. To evaluate the role of MYH9 SNP on developing of renal failure. Method :This study depending on “methodology of Case-control study”, subjects involved were one hundred as patients and control; 50 “patients” complaining renal failure and 50 apparently healthy controls. DNA was extracted from venous blood. The “MYH9 gene polymorphisms” were recognized by applying the procedure of (“PCR-RFLP”). Result :Genotype at rs4821480 in patients with RF: finding that obtained were TT (59%), GT (34%), and GG (6.0%) and for control TT (45%) GT (40%) ,GG(15%). This analysis of data indicated the TT genotype homozygote at rs4821480 convenes independently a threating of RF than does the GT and GG genotypes. a variation in the genotype at rs3752462 was shown in patients with RF: CC (4.8%), CT (73.2%), and TT (22.0%). Conclusion :The outcomes indicate that the CT genotype at rs3752462 confers independently a risk factor of RF than those of TT and CC genotypes. There is no significant correlation between distribution of alleles and age, sex, resident, jobs, smoking habit, family history, body mass index (BMI), and medical history (P>0.05).
The Diagnostic Accuracy of Phalen Test and Prayer Test in Carpal Tunnel Syndrome Suroso Agus Widodo1, Fatchur Rochman1, Ratna D. Haryadi1, Patricia Maria K1
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.3224

Abstract

Background of Study: Carpal Tunnel Syndrome is a series of symptoms and signs because of pressure on the median nerve in a small space in the wrist called carpal tunnel. In diagnosing CTS, it is required anamnesis and thorough physical examination which includes CTS provocation test, for instance Phalen test, Prayer test, and Tinel sign. The aim of this study is to reveal the diagnostic accuracy of Phalen test and Prayer test in diagnosing CTS. Methods: The samples that fulfilled inclusion criteria were 19 subjects went through Phalen test, Prayer test, and nerve conduction study using CSI in Department of Physical Medicine and Rehabilitation Dr. Soetomo General Hospital Surabaya, Indonesia. The nerve conduction study using CSI was conducted by EMG Cadwell equipment. The data analysis was conducted by using SPSS software. Result of the Study: The sensitivity of the Phalen test and Prayer test combination in diagnosing CTS was 94.1 %. The specificity of Phalen test and Prayer test combination in diagnosing CTS was 100%. The positive predictive value was 100% while the negative predictive value was 66.7%. The result of person chisquare examination was obtained asymp. Sig value of 0.001 < ? 0.05. Conclusion: There was a correlation between the combination of Phalen test and Prayer test with CTS.
Conservative & Operative Management of Tuberculous Spondylitis in Children Teuku Arief Dian1, Komang Agung Irianto2
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.3226

Abstract

Background: Tuberculosis is a deadly disease worldwide. Tuberculosis usually occurs in the lung, but there are other tuberculosis most commonly afflicted by the patient and involves the spine and is called tuberculosis of bones and joints. Management of tuberculous spondylitis is conservative and operative. Aim: This study aimed to compare the results of conservative and operative therapy in the management of tuberculous spondylitis in children. Methods: The sample used was teaching with tuberculous spondylitis in Dr. Soetomo General Hospital who underwent operative and conservative therapy that became group 1 and group 2. Inclusion criteria included patients aged <18 years old, suffering from tuberculous spondylitis by conservative or operative therapy in Dr. Soetomo Hospital. Results: In patients receiving conservative therapy, the Visual analog scale (VAS) decreased significantly (p = 0.001), while frankle improved but not significantly (p = 0.157). Cobb’s angle of patients receiving conservative therapy increased significantly (p = 0.007). Patients who received operative therapy showed significant improvement of VAS and Frankle (p = 0.001 and p = 0.011). The patient’s Cobb’s angle after surgery decreased but it was not significant (p = 0.575). Conclusion: The role of surgical action has an important role in the treatment of tuberculous spondylitis and gives better results than conservatives in patients with pain, neurological deficits and Cobb’s angle progression.

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