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INDONESIA
Indian Journal of Forensic Medicine & Toxicology
Published by Official Organ of Indian Association of Medico-Legal Expert
ISSN : -     EISSN : -     DOI : -
Core Subject : Health,
Public Health
Arjuna Subject : Kedokteran - Epidemilogi
Articles 5,497 Documents
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Toxopathological and Cytogenetic Effects of Commercial Sweetener Aspartame after Chronic Oral Administration in Rat Pups Ali, I. Al-ameedi1 , Zahraa M. Ayad, Falah Mousa Kadhim AL-Rekabi3
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 3 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i3.10531

Abstract

Objective: This study was done to evaluate the potential toxic effect of aspartame (APS) artificial sweetener after chronic oral administration in rat pups as a model for children that consumption high quantities of different types of sweets and juices from the peddler, regularly and daily. Methods: Twenty-four rat pups were divided equally into three groups. Therapeutic dose group (T1) and double dose group(T2) received 0.08, 0.16 g/kg. body weight(BW), respectively, while control group (C) received distilled water orally for 90 (d)days. Results: The result of present study revealed that there was an increased consumption of food, water and arising nervous signs(aggressive) in T1 and T2 groups comparing with control. The cytogenetic study includes the mitotic index and blast index showing a substantial decline relative to the control one in both treated groups. While the blast index showed a significant reduction(P<0.05) in T2 relative to T1 and the control group. No chromosomal aberration observed in all groups exposed to aspartame. Different histopathological lesions were recorded in the liver of T1 group represented by inflammatory cell (neutrophil & mononuclear cell) aggregation around the blood vessels. While noted in a double dose group (0.16g/ kg.bw), a granulomatous lesion with mild change in fat is shown. Conclusion: Used daily for lengthy periods ASP has cytogenetic and pathological risks.
Examining The Forensic Toxicity of Ricin Using Lc/Ms Techniques Bandr Siraj Fakiha
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 3 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i3.10532

Abstract

As one the naturally occurring toxins, Ricin is classified among the deadliest poisons available. Ricin and Ricinus communis agglutinin (RCA120) are derived from the castor bean plant. Ricin and its related activities can be detected using either mass spectrometric (MS) assay or Liquid Chromatography (LC). Further, the two methods can be to differentiate ricin from RCA120 because it is less toxic of the two. The sequence of Amino acid is identified by monitoring the active ricin using mass spectrometric. This study discusses how LC and MS methods can be applied to quantify, detect, and differentiate ricin from RCA120 in test samples. On the overall, the two methods were applied to tell aside ricin samples from RCA120. The study concluded that mass spectrometry is the most efficient approach in identifying ricin from RCA120.
Nurses knowledge about Management Extravasation Intravenous Cytotoxic Medication At Amal National Hospital in Baghdad City Batool Kadham Hussin1 , Wrood Abdul Razaq Ahmed2
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 3 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i3.10533

Abstract

Background: Extravasation, the unintentional leak of an anticancer agent from a vessel into the close tissues, is an uninvited and difficult problem that can lead to permanent local harms and severe disability. Objectives: To assess nurse’s knowledge about management extravasation vesicant intravenous cytotoxic medication. Methodology: Descriptive design using a self-administered questionnaire was employed. At al-Amal national hospital for tumor treatment in Baghdad city from 2nd December 2018 to 10th February 2019). Random sampling method. The sample size was 45 nurses completed a questionnaire about management extravasation vesicant intravenous chemotherapy. Instruments: developed by the researcher consist of three sections the first section to assess the demographic data. And the second section questionnaire consists of 20 items divided into two parts to measure the information of team nurses on vesicant drug and management extravasation Vesicant intravenous chemotherapy. Data analysis by using the Statistical Package for Social Sciences version (SPSS) 23.0 included. (Frequency, percentage, Kruskal Wallis H test, Chi-square test, and Mann-Whitney U test). The level of significance was the threshold at p<0.05. Results: shows that the high percentage (42.2%) of oncology nurses ages (30-39 years old). Most of them (57.8 %) were female. The education level represents (42.2%) of nurses were from nursing institute graduates, the high percentage (46.7%) of them their experience in oncology unite were (5-9) years. Mostly no training session. Inferential there are statistically significant between education levels groups the nursing college showed a higher mean knowledge score than other levels. also, a higher significantly difference was observed between mean knowledge and participate with Training courses by mean (36.40) The researcher decide that nurse’s knowledge is the poor component about vesicant cytotoxic and management extravasation according to of assessment result Conclusion: there is a need for structuring a permanent education program due to the poor scientific of nurse’s knowledge about the vesicant and management of extravasation by chemotherapeutic drugs. Therefore, the issue of training courses should be highlighted for it is an effective role in improving the performance of nurses.
Correlation between BMI and Thyroid Hormones in Infertile Groups Etab Abdul-Ameer Al-ogla1 ,Manar Saad Hussain2, Suad Torki Abd-AL abbas3
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 3 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i3.10534

Abstract

Infertility is the failure to become pregnant after 12 months of copulation without contraception . Thyroid defeat in function can caused to the: menstrual disorder, an ovulatory phase and lower fertility. This search formed to assess the importance of thyroid syndromes in infertility women and importance the autoimmunity by assessing value of TSH, T3, T4, & anti Thyroid peroxidase antibody in infertile woman comparison the consequences with women controls. The direction in this search started from March 2015 to September 2015 at Karbala Maternity Hospital, infertility unit, and some private clinics. Showed significant relation between TPO and BMI in controls and patients p –value (<0.002 ,<0.0001) respectively, and significant relation between BMI and T4 in patients and controls p-value (<0.0001) , and shows significant relation between , the relation between BMI and sex hormones shows no significant relation with LH in patients but significant in controls p-value (<0.0001) and relation with FSH was not significant in patients and controls , and relation with E2 shows significant relation in patients p-value (<0.01) but no significant in controls. This search directed to estimation the relationship between thyroid function and sex hormones with BMI. Where the height of BMI affects the body to increase TPO and T4 and affect estradiol , we recommend that women maintain the body weight within normal
Effectiveness of an Educational Program on Primary School Teachers’ Knowledge about Attention -Deficit/Hyperactivity Disorders Hassam M. Al-Amarei1 , Saja H. Mohamed2
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 3 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i3.10535

Abstract

The child is one of the most important assets of the nation, the future of mankind, the source of its true power, the promotion and enhancement of the child’s life and welfare is also anchored on the moral supervision and support given by his parents or guardians in order for a child to succeed, parents exert a lot of influence on their child’s cognitive development in the early years, the investigator made an insight into the aim of the study as follows: To determine the effectiveness of the teaching program on teachers knowledge. The study was conducted on at governmental primary schools in Al-Najaf City/ Iraq. A total of the (10) governmental primary schools selected randomly from total (253) governmental primary schools in Al-Najaf City. A purposive (non- probability) sample of (70) primary school teachers’ were selected from the candidate schools were included in the present study. During the period of 1st September 2018 to 20th February 2020. The data was collected by questionnaire which consisted of two main parts, first part consists socio demographic sheet. Second part is about knowledge which consist of (31) items scale of teachers’ knowledge about children with ADHD . Findings revealed confirmed that the teachers who not attended for program about ADHD have poor level of knowledge pupils with attention -deficit/hyperactivity disorder among elementary school teachers. While the teachers who attended for program about ADHD have improve and increase knowledge about ADHD in phase two, and three. Thus, it is recommended for responsible parties to notes the need for greater efforts to teachers should trained to recognize students with behaviors problems / disorders in their classes to provide them with proper and timely education as well as necessary referral for their assessment.
Anatomical and Immunohistochemical Variations Regarding the Epidermal Stem Cell among Different Traumatic Fingers of Hands in Iraqi Male Workers Hatem A Hatem1 , Ahmed S. Mazyon2 , Hala Mohammed Majeed3
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 3 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i3.10536

Abstract

Background: The role of stem cell during the whole life of human constricted into two stages. First stage occurred during prenatal life when stem cell take part in formation of organ in process called embryogenesis. Second stage occurred in postnatal life when these cells contribute in regeneration of damaged or old tissue as repairing or substituting cell in adults. Patient and Method: 150 male volunteers who work in different industries with traumatic finger of the right or left hand (33 right thumb,25 right middle finger ,22 right little finger,28 left thumb,26 left middle fingers 16 left little finger) were taken on from the Department of surgery, Baghdad Hospital, Baghdad; Iraq from February 2019 to October 2019. Results: Anatomical results showing that The grip was affected only in case of traumatic thumb. Vimentin rich-stem cells were highly positive in the proximal epidermal areas of traumatic fingers more than the stem cells in the distal areas of the same fingers. Conclusion: there is a little hope in the near future that the injured or even amputated finger or any part of the body could be replaced by new one made by culturing stem cells in laboratories.
Gene Expression and Levels of Plasma Protein Tyrosine Phosphatase Non-Receptor Type 22 (PTPN22) in Pulmonary Tuberculosis Patients and Their Household Contacts in Makassar, Indonesia Ibrahim A1,3, Djaharuddin I2 , Hidayah N1 , Subair1 , Handayani I1 , Tenriola A1 , Massi MN4,5
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 3 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i3.10537

Abstract

Background: The protein tyrosine phosphatase non-receptor type 22 (PTPN22) gen,has been involved in the immune response to tuberculosis infection by affecting the inflammatory response and subsequent anti microbial immunity. This study aims to determine the PTPN22 expression and differences in the levels of PTPN22 in pulmonary TB patients (PTB) with household contacts and healthy control. Methods: We analyzed PTPN22 expression and the level of plasma PTPN22 from pulmonary tuberculosis patients (PTB), household contacts and healthy control using real time PCR and ELISA method. Results: ThirtyPTB, 30 household contacts and 30 control were involved in this study. Analysis of the assocation of PTPN22 gene expression against TB showed that PTPN22 gene expression was 7.3 times upregulated compared to household contact and 12.1 times upregulated compared to healthy controls.Levels of plasma PTPN22 in PTB: 10.0620 ng/ml, in Household contact: 6.7923 ng/ml and in control: 4.4293 ng/ These values did not differ significantly between the patients, household contact and control. Conclusion: Our study results found that PTPN22 gene expression is significantly increased in PTB than household contact and control.Levels of plasma PTPN22 in PTB patientsdid not differ significantly than in household contact and control.
Quantitative and Histological Study of the Effect of Cadmium Oxide on Both Body and Kidney of Mice Khalid H. Gathwan1 , Ahmed Anwar Albir1
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 3 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i3.10538

Abstract

The present study was conducted using 24 normal male of Swiss white mice weighing (36-40 gm), 70 days old .The mice were divided into four groups of six mice each. The mice of control group were fed pellet and given tap water during the entire period of the experiment (30 days).The other three groups of mice were given cadmium oxide orally at doses of (7.0 mg / kg body wt., 14.1 mg / kg body wt., and 22.3 mg / kg body wt.) consecutively every day for 30 days and weight in gm was taken once a week. With standard histological techniques, samples were obtained from kidney of the mice. The body weights along with kidney weights were decreased with increase of doses. Also it has been concluded that cadmium oxide caused damages in renal corpuscle (Bowman’s capsule and glomerulus) and renal cortical tubules as well as decrease in body weight and kidney weight (wt.).
Clove (Syzygium aromaticum) Effect on Growth Malassezia Furfur and Aspergillus sp on Media Leka Lutpiatina1 , Pebri Fitria Lestari2 , Dwi Intan Purnama Sari2 , Haitami1 , Rifqoh1 , Nurlailah1
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 3 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i3.10539

Abstract

Background: Malassezia furfur and Aspergillus sp are fungi associated with infection in humans. One of the plants that can use as anti fungi is clove (Syzygium aromaticum). Aim: The purpose of this study was to determine the growth barriers of Malassezia furfur and Aspergillus sp on media with the addition of Clove Powder (Syzygium aromaticum). Material and Method: The equipment used by cloves (Syzygium aromaticum) is a part of the reddish green flower. The samples used in this study were Malassezia furfur and Aspergillus sp. Specimens planted on Saboraud Dextrose Agar media with the addition of clove powder (Syzygium aromaticum) in various concentrations. Results: Malassezia furfur in media with clove powder concentration of 0%; 0.05%; 0.1% shows the number of colonies 1330; 1135; 765. Aspergillus niger, Aspergillus flavus, Aspergillus fumigatus on media with clove powder concentration of 0%; 0.05%; 0.2% indicates colony diameter of 6.8 cm; 5 cm; 3.7 cm (Aspergillus niger), 6.7 cm; 5 cm; 4.3 cm (Aspergillus flavus), 7 cm; 5 cm; 2.3 cm (Aspergillus fumigatus). Conclusion: Media with Addition of Clove Powder (Syzygium aromaticum) can inhibit the growth of Malassezia furfur and Aspergillus sp.
Assessment of Aggression among High Schools Students Mansour Abdullah Falah Al-Zorfi1 , Hussein Jassim Muhammad Al-Ibrahimi.2
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 3 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i3.10540

Abstract

Background: Aggression is a behavioral characteristic that refers to forceful actions or procedures (such a deliberate attack) with intentions to dominate or master. It tends to be hostile, injurious, or destructive, and is often motivated by frustration for an individual, aggressive behavior is considered understandable and normal under appropriate circumstances, but when it is frequent, intense, lasting, and pervasive, it is more likely to be a symptom of a mental disorder. Likewise, aggression between groups, can be in the form of healthy competition, but can become harmful when unfair or unjust disadvantage or frustration is perceived, leading to hostility. Objectives: assessment aggression among high school students. Methodology: A descriptive cross-sectional study was carried out in order to achieve the stated objectives. The study has begun from 1st September 2018. Settings of the Study: The settings of the study include (41) High secondary schools which are distributed in (3) Districts of Al-Najaf Governorate, urban (23) schools and rural (18) schools, these schools are systematic randomly selected. Results: most majority was moderate aggressive by 52.7%. Conclusions: this study show which included an overall assessment of Aggressive, where the study showed that the most majority was moderate aggressive. Recommendations: Supporting educational methods by the Educational Committee that limits aggressive behavior of adolescents in schools, such as (moving away from scenes of an aggressive nature, beating, violence, fighting, quarrels, and blood scenes). And The teacher devotes part of the lesson time to clarifying issues and harms of aggression, and to show the benefits of tolerance and contentment. and The school administration cooperated with the teenager’s family to identify the causes of his aggression. Finally, The Ministry of Education is working to create posters that reject aggression and suspend it throughout the school.

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