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Jurnal Farmasi
Published by Sekolah Tinggi Ilmu Kesehatan Nasional
ISSN : 23027436     EISSN : 26568950     DOI : https://doi.org/10.37013/jf
Core Subject : Health,
Dentistry Health Professions Medicine & Pharmacology Nursing Public Health
JURNAL FARMASI (Journal Of Pharmacy) adalah jurnal ilmiah resmi yang dikeluarkan oleh Sekolah Tinggi Ilmu Kesehatan Nasional dengan nomor p-ISSN 2302-7436 e-ISSN 2656-8950. JURNAL FARMASI (Journal Of Pharmacy) berisikan jurnal-jurnal ilmiah dalam semua aspek ilmu pengetahuan dan teknologi di bidang Farmasi dan kesehatan antara lain: Farmakognosi dan Fitokimia meliputi Pengembangan Simplisia, Budidaya Tanaman Obat, Isolasi, Skrining Fitokimia, dan Identifikasi Obat Bahan Alam Indonesia. Biologi meliputi Biologi Molekuler, Bioteknologi, Mikrobiologi, Immunologi, Parasitologi, Biomedisinal Teknologi Farmasi meliputi Farmasetika, Teknologi dan Formulasi Sediaan Obat, Teknologi dan Formulasi Sediaan Obat Bahan Alam Indonesia. Ilmu Kimia meliputi Kimia Analisa, Kimia Organik, Sintesa Obat, Kimia Medisinal, Pemodelan Molekul, Biokimia, dan Kimia Lingkungan. Farmakologi meliputi Farmakologi, Farmakokinetik, Farmakoterapi, dan Toksikologi. Farmasi Klinik dan Komunitas meliputi Farmakoekonomi, Farmakovigilan, Analisis dan Evaluasi Penggunaan Obat, Monitoring Efek Samping Obat, Analisa Kebijakan Kefarmasian, Evaluasi kegiatan Kefarmasian, Evaluasi Efektifitas Penggunaan Obat, Evaluasi Kualitas Hidup Pasien.
Arjuna Subject : Profesi Kesehatan - Profesi Kesehatan (Lain-Lain)
Articles 6 Documents
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Search results for , issue "Vol 12, No 1 (2023)" : 6 Documents clear
Anti-Inflammatory Test of Topical Cream Preparations from Ethyl Acetate Fraction of Johar Leaves (Cassia siamea L.) in White Mice Audri Nandia Apriyanti; Diah Pratimasari; Eka Wisnu Kusuma
Jurnal Farmasi (Journal of Pharmacy) Vol 12, No 1 (2023)
Publisher : SEKOLAH TINGGI ILMU KESEHATAN NASIONAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37013/jf.v12i1.223

Abstract

Johar leaves contain chemical compounds, there are alkaloids, saponins, tannins, flavonoids, barracol, sitosterol. This study aims to determine the anti-inflammatory effect of the johar leaf ethyl acetate fraction topically, to determine the optimum concentration of johar leaf ethyl acetate fraction in cream preparations, and to determine the physical properties of the johar cream and cream stability. The leaves of johar (Cassia siamea L.) were extracted using the maceration method with 70% ethanol. The ethanol extract of johar leaves was fractionated with water, n-hexane and ethyl acetate as solvents. The ethyl acetate fraction of johar leaves was made cream with a concentration of 2.5%, 5% and 10%. The basis and the three formulas were tested for the physical quality of the cream including the organoleptic test, homogeneity, viscosity, spreadability, adhesion, cream type, pH and cream stability. The anti-inflammatory effect was determined by measuring the thickness of the back skin of the mice. The data obtained were analyzed statistically One Way Anova with a confidence level of 95% to determine that there were significant differences between treatment groups. The results showed that the leaf ethyl acetate fraction cream could provide topical anti-inflammatory effects on carrageenan-induced white mice with an effective concentration of 5% with (% PI) of 36.67%. The ethyl acetate fraction of johar leaves with a concentration of 2.5% and 5% fulfilled the requirements for the physical properties of the cream, but the cream with a concentration of 10% did not meet the requirements in the pH test. And the ethyl acetate fraction cream of johar leaves was stable in 1 month storage
Kajian Etnofarmasi Penggunaan Tumbuhan Obat Sebagai Alternatif Pengobatan Diare Oleh Masyarakat Suku Osing Dusun Krajan Amira Septa Sanjaya; Hartono Hartono; Truly Dian Anggraini
Jurnal Farmasi (Journal of Pharmacy) Vol 12, No 1 (2023)
Publisher : SEKOLAH TINGGI ILMU KESEHATAN NASIONAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37013/jf.v12i1.203

Abstract

Diarrhea is a disease whose existence is still a global health problem, including Indonesia. Diarrhea is in the top 10 diseases that still occur frequently and is ranked 5th in the Osing Tribe. For the treatment of diarrhea, the Osing tribe still uses plants as medicinal plants that are used for generations. This study was conducted to examine how ethnopharmacy in the Osing tribe is intended as a preliminary study for the development of traditional medicine carried out by the Osing tribe as traditional medicine/phytopharmaca. This research is a descriptive study using qualitative methods with sampling techniques using snowball sampling through open-ended interviews by filling out informant information sheets and involving 22 informants from the Osing Tribe, Krajan hamlet, Kemiren, Glagah, Banyuwangi, East Java. The results of the ethnopharmaceutical research in the Osing Tribe showed that there were 8 types of plants and an analysis was carried out using ICF (Informant Consensus Factor) with the results of 0.6 being interpreted as being trusted and used as a hereditary treatment, PPV (Plant Part Value) to calculate the plant part used. with a yield of 50% leaves, 23% fruit, 27% rhizome and FL (Fidelity Level) to determine the types of plants most often used in treating diarrhea with the highest yield of 100%, including Psidium guajava L and Manihot esculenta.
AN OVERVIEW OF THE LEVEL OF KNOWLEDGE ON SELF-MEDICATING VITAMIN C STUDENTS D III PHARMACY STIKES WDH TANGERANG DURING THE COVID-19 PANDEMIC Anis Dwi Kristiyowati
Jurnal Farmasi (Journal of Pharmacy) Vol 12, No 1 (2023)
Publisher : SEKOLAH TINGGI ILMU KESEHATAN NASIONAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37013/jf.v12i1.201

Abstract

Background: Vitamin C is an essential water-soluble vitamin that is widely used as a body supplement. Misuse of the dosage will cause unwanted side effects such as nausea vomiting, diarrhea, increasing the risk of diabetes. Purpose: This study is to find out an overview of the level of knowledge on self-medicating the use of vitamin C for D III Pharmacy students of STIKes Widya Dharma Husada Tangerang during the Covid-19 pandemic.  Method: This study is a descriptive study with 96 respondents taken by the cross-sectional method. Data were obtained through questionnaires and analyzed using percentages. Results: The results obtained in this study are the characteristics of respondents based on age Most of them are found at the age of 17-25 years, namely 87.5%, based on gender Most of them are found in women, namely 84.37%, based on work more than half of them are found in those who are not working, namely 52.08%, and based on a history of exposure to covid-19 more than half of them are found in those who have been exposed to covid-19, namely 73.96%,  while the characteristics of respondents' knowledge about the use of well-informed vitamin C were highest based on the age of 17-25 years as much as 84.37%, in the female sex as much as 81.25%, in unemployed work as much as 50%, in the history of exposure to covid-19 who had been exposed to covid-19 as much as 70.83%. Conclusion: The results of this study show that the concentration of the level of knowledge on self-medicating the use of vitamin C for D III Pharmacy students of STIKes Widya Dharma Husada Tangerang during the Covid-19 pandemic was 96.88% included in the "Good" category.
Penetapan Kadar Fenolik dan Flavonoid Total Ekstrak Etanol Buah Parijoto (Medinilla speciosa Blume) dengan Metode Spektrofotometri UV-Vis Prashinta Nita Damayanti; Fania Putri Luhurningtyas; Lyna Lestari Indrayati
Jurnal Farmasi (Journal of Pharmacy) Vol 12, No 1 (2023)
Publisher : SEKOLAH TINGGI ILMU KESEHATAN NASIONAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37013/jf.v12i1.222

Abstract

Parijoto (Medinilla speciosa) has a wide range of pharmacological activities due to its secondary metabolite content, especially flavonoid, and phenolic compounds. Flavonoid and phenolic compounds have a major role in human health with their activities as antioxidants, anti-inflammatories, antimicrobials, etc. This study aimed to determine the total levels of phenolic and flavonoid compounds from the ethanol extract of Parijoto fruit. Parijoto fruit is obtained from Bandungan, Semarang Regency, Central Java. Extraction was carried out by maceration method with 70% ethanol solvent then concentrated using a rotary evaporator. The total phenolic and flavonoid content amount was determined using the colorimetric method with Folin-ciocalteau complex reagent on phenolic with gallic acid as the reference standard and AlCl3 complex reagent on flavonoids with quercetin as the reference standard. Absorbance was measured using a UV-Vis spectrophotometer. The results showed that the color of the viscous extract of Parijoto fruit was dark brown with a yield of 6.67% w/w. The total phenolic content of the ethanol extract of Parijoto fruit was 21.67 µgGAE/g extract and the total flavonoid content was 9.21 µg QE/g extract.
Analisis Tingkat Pengetahuan dan Persepsi Swamedikasi Obat Analgetik pada Siswa di SMAN 3 Cirebon Febia Nurrahma Berlian; Ahmad Azrul Zuniarto; Siti Pandanwangi; Encis Rubihatlan; Ajni Minhatul Maula; Azriel Farhan Alfawwaz; Akil Salafi; Deby Sri Virgianti
Jurnal Farmasi (Journal of Pharmacy) Vol 12, No 1 (2023)
Publisher : SEKOLAH TINGGI ILMU KESEHATAN NASIONAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37013/jf.v12i1.216

Abstract

ABSTRAKSwamedikasi adalah pemilihan dan penggunaan obat oleh individu atau anggota keluarga tanpa instruktur okter, untuk mengobati kondisi yang dikenali ataupun didiagnosis sendiri. Analgetic atau yang sering disebut dengan obat penghalang rasa nyeri tanpa menghilangkan kesadaran. Penelitian ini bertujuan untuk mengetahui tingkat pengetahuan siswa tentang swamedikasi obat analgetik di SMAN 3 Cirebon, untuk mengetahui persepsi siswa tentang swamedikasi obat analgetik di SMAN 3 Cirebon, untuk mengetahui tingkat tingkat pengetahuan dan persepsi siswa terhadap swamedikasi obat analgetik berdasarkan karakteristik siswa, dan untuk mengetahui tingkat pengetahuan dan persepsi siswa terhadap swamedikasi obat analgetik berdasarkan indikator soal yang dinilai. Metode penelitian ini adalah penelitian kuantitatif dengan menggunakan desaain deskriptif. Teknik pengambilan sampel menggunakan Teknik purposive sampling. Pengumpulan data menggunakan e-quisioner (google form) yang diberikan kepada 82 respponden yang memenuhi kriteria inklusi dan ekslusi. Teknik analisa data penelitian ini menggunakan analisis deskriptif. Hasil penelitian tingkat pengetahuan dan persepsi siswa tentang swamedikasi obat analgetik di SMAN 3 Cirebon diketahui tingkat pengetahuan memperoleh nilai  rata-rata 78,96% termasuk kedalam kategori baik. Dan persepsi siswa memperoleh nilai rata-rata 83,63% termasuk kedalam kategori sangat baik. Berdasarkan karakteristik responden yang mempunyai pengetahuan baik dan persepsi dangat baik paling banyak terdapat pada usia 16 tahun, jenis kelamin perempuan, pekerjaan orangtua sebagai karyawan swasta, nyeri yang di derita responden 1 bulan terkahir yaitu nyeri badan/otot, Riwayat penggunaan obat yaitu parasetamol dan tempat mendapatkan obat yaitu Apotek. Tingkat pengetahuan siswa tentang swamedikasi obat analgetik berdasarkan indicator soal yang dinilai dengan benar yaitu : 78,66% pada indikator tingkat keamanan dan ketepatan penggunaan obat, 74,39% pada indikator dosis obat, 93,9% pada indikator kegunaan obat obat, 64,63% pada indikator cara penggunaan obat 74,39% pada inidkator efek samping obat, 89,02% pada inidkator cara penyimpanan, 97,56% pada indicator waktu kadaluwarsa obat, dan 64,63% pada inidkator pemusnahan obat.Kata kunci: Swamedikasi, Analgetik, Tingkat Pengetahuan, Persepsi
UJI EFEKTIVITAS ANTIBAKTERI EKSTRAK ETANOL DAUN PALA (Myristica fragrans Houtt) TERHADAP Staphylococcus epidermidis Marcelina Wandan Wisdyafanny; Yusianti Silviani
Jurnal Farmasi (Journal of Pharmacy) Vol 12, No 1 (2023)
Publisher : SEKOLAH TINGGI ILMU KESEHATAN NASIONAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37013/jf.v12i1.221

Abstract

Acne vulgaris atau jerawat dapat disebabkan oleh bakteri, salah satunya  Staphylococcus epidermidis yang akan menghasilkan enzim lipolitik yang mengubah sebum menjadi massa padat, kemudian akan menyumbat saluran kelenjar sebasea. Daun pala mengandung senyawa saponin, triterpenoid, tanin, dan flavonoid sebagai antibakteri. Tujuan penelitian ini adalah untuk mengetahui daya hambat ekstrak etanol daun pala (Myristica fragrans Houtt) terhadap pertumbuhan Staphylococcus epidermidis. Penelitian ini menggunakan metode penelitian deskriptif eksperimental untuk mengetahui efektivitas antibakteri ekstrak etanol daun pala (Myristica fragrans Houtt) terhadap Staphylococcus epidermidis. Sumber data penelitian ini adalah data primer yaitu berdasarkan hasil zona hambat terhadap Staphylococcus epidermidis dengan pemberian ekstrak etanol daun pala (Myristica fragrans Houtt) dengan konsentrasi 20%, 40%, 60%, 80%, dan 100%. Hasil penelitian menunjukkan bahwa ekstrak etanol daun pala dapat digunakan sebagai antibakteri terhadap Staphylococcus epidermidis. Rata-rata diameter zona hambat ekstrak daun pala yang terbentuk pada konsentransi 20% yaitu sebesar 10,45 mm, pada konsentrasi 40% yaitu sebesar 11,4 mm, pada konsentrasi 60% yaitu sebesar 11,9 mm, pada konsentrasi 80% yaitu sebesar 12,35 mm, dan pada konsentrasi 100% yaitu sebesar 12,6 mm. Konsentrasi 100% mampu menghambat Staphylococcus epidermidis dengan rata-rata diameter zona hambat paling luas yaitu sebesar 12,6 mm.

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