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Jurnal Buana Farma
Published by Universitas Buana Perjuangan Karawang
ISSN : -     EISSN : 27972100     DOI : 10.36805
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology
The major focus of Jurnal Buana Farma is to publish articles in the area of Experimental Pharmacology, Clinical Pharmacy, Pharmaceutical Technology, Pharmacoeconomy, Pharmacognosy, Pharmaceutical chemistry.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 26 Documents
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Search results for , issue "Vol. 4 No. 4 (2024): Jurnal Buana Farma : Jurnal Ilmiah Farmasi" : 26 Documents clear
POTENSI TANAMAN HERBAL SEBAGAI STIMULAN SISTEM SARAF PUSAT: LITERATURE REVIEW ARTICLE Suri, Nurma; Oktoba, Zulpakor; Yulianti, Mega Intan
Jurnal Buana Farma Vol. 4 No. 4 (2024): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v4i4.960

Abstract

Energy drinks are consumed as supplement to increase energy and reduce fatigue. Herbal medicine has proven reduce fatigue in the body. This literature review aims to determine the types of herbal medicine that have properties as stimulants. This study used descriptive methode using the Population-Intervention-Controling-Outcome Framework. A literature search on studies published in the period 2012-2022 on the Google Scholar and Pub-Med using the keywords: stimulant, central nervous system, tonic, and herbal. Articles that cannot be accessed in full and herbal medicine that are not original from Indonesia will be excluded as samples. There were 1937 articles obtained based on the keywords used, a total of 91 articles met the inclusion criteria and 60 articles were excluded. Based on 30 articles reviewed, there are 31 types of herbal medicines that can increase stimulants with the most family is zingiberaceae and piperaceae. The combination of plant has a better stimulant effect than using the single plants. In vivo test method with the swimming endurance test as the most widely used. Flavonoid, alkaloid and terpenoid compounds are most likely to be effective as stimulants which have the same mechanism with caffeine through inhibition of Adenosine A1 receptors. This study shows there are 31 herbal medicine that have the potential to increase stimulants. Secondary metabolites which stimulant effects are flavonoids, alkaloids and terpenoids
Literature Review Artikel: MANFAAT MINYAK ATSIRI PADA BERBAGAI BAGIAN TUMBUHAN Fikayuniar, Lia; Audiny, Cindy; Ibrahim, Asshasyfa; Hidayat, Dhivira Azfari Pratama; Julianti, Dine; Ramadhani, Putri; Zaenudin, Rian Ahmad
Jurnal Buana Farma Vol. 4 No. 4 (2024): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v4i4.1078

Abstract

Essential oils are aromatic compounds naturally found in various parts and types of plants. This study aims to evaluate the benefits of essential oils extracted from different plant parts using various methods. The research was conducted through a literature review by analyzing data from multiple journal articles. The review revealed that essential oils extracted from different plant parts exhibit diverse compositions and benefits. Essential oil from the leaves of zodia (Evodia suaveolens), obtained through distillation, yielded 0.6471%, with 4(5H)-Benzofuranone identified as the main component through GC-MS analysis. Meanwhile, hydro-steam distillation of kaffir lime (Citrus hystrix) peel produced essential oil containing 25 components, primarily demonstrating antioxidant activity. Steam distillation of langsat (Lansium domesticum) fruit peel yielded essential oil with a 0.18% yield, comprising monoterpenoid and sesquiterpenoid compounds as its major components. This study highlights the potential of essential oils from various plant parts as sources of bioactive compounds with diverse benefits.
ANALISIS KANDUNGAN MINYAK ATSIRI EKSTRAK RIMPANG KENCUR (Kaemprefia galangan l.,) DENGAN MENGGUNAKAN METODE KLT Fikayuniar, Lia; Hanita, Icha; Aulia, M Azriel; Syarifah, Nadia Siti; Khairani, Risda Aulia; Pijriah, Sulis Salsa; Agrestia, Tasya
Jurnal Buana Farma Vol. 4 No. 4 (2024): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v4i4.1096

Abstract

Simplicia is a natural ingredient that is dried and used as medicine and has not undergone any processing involving any chemical processes. Simplicia is divided into three types, namely animal, pelican and vegetable simplicia. Drying simplicia must be done under appropriate conditions to avoid loss of active substance content. This research uses galangal (Kaempferia galanga) as the simplicia used. Galangal is used in various traditional treatments, such as rheumatism, asthma, stomach ulcers, malnutrition, diarrhea, coughs, fever, as a concoction to increase stamina and digestive tract disorders. The chemical ingredients in kencur simplicia, such as essential oils and curcuminoids, have good properties for the body. This research uses a thin layer chromatography method to identify the essential oil content in galangal rhizomes.
PENGGUNAAN METFORMIN PADA PASIEN POLYCYSTIC OVARY SYNDROME (PCOS) Salasanti, Citra Dewi; Agustini, Dewi Darwati; Ramdani, Amalia Dewi
Jurnal Buana Farma Vol. 4 No. 4 (2024): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v4i4.1139

Abstract

Infertility in women of reproductive age with Polycystic Ovary Syndrome (PCOS) in Indonesia is increasing. Insulin resistance occurs in some PCOS patients, so the use of insulin sensitivity-enhancing drugs such as metformin is recommended. This study was conducted to determine the use of metformin in PCOS patients at independent doctor's practices in Bandung City. The study was conducted as an observational descriptive study with data collected retrospectively using purposive sampling. Data were taken from patient medical records and interviews with the doctor in charge. The sample in this study consisted of patients who met the inclusion and exclusion criteria. The data obtained were then summarized and displayed in table form. The results showed that the majority of PCOS patients were 26-30 years old with marriages that had lasted for 3 years. Ovulation and pregnancy in PCOS patients who used oral metformin treatment occurred in 15% of cases. The metformin used had a dose of 500-850 mg, which was given twice a day for 4-9 months.
REVIEW: POTENSI KETIDAKTEPATAN PENGGUNAAN OBAT PADA PASIEN GERIATRI DI BEBERAPA RUMAH SAKIT DI INDONESIA Pratama, Gumilar; Wahyuningsih, Sri; Hermanto, Faizal
Jurnal Buana Farma Vol. 4 No. 4 (2024): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v4i4.1144

Abstract

Inappropriate medication use in geriatric patients, particularly related to Potentially Inappropriate Medications (PIMs), is a major concern in elderly healthcare management. This study aims to explore the prevalence and types of PIMs found in several hospitals in Indonesia. A narrative review method was employed, with journal data searched using the query: “Potentially Inappropriate Medications” OR “Potentially Inappropriate Prescribing”, “identification of PIMs”, “evaluation of PIMs”, “Beers Criteria” OR “Beers Criteria”, “STOPP Criteria”, “PRISCUS PIMs” in Google Scholar, Garuda, and PubMed databases. Articles selected met the inclusion criteria, including national and international journals published within the last 10 years and available in full text. The results showed that the prevalence of PIMs in a hospital in Semarang was 487 medication items, with sodium diclofenac being the most frequently found medication (12.96%). At RSUD Arjawinangun, the occurrence of PIMs reached 56.82%, with furosemide being the most dominant medication (22.73%). A study in Jakarta showed that prescription review by pharmacists successfully reduced the occurrence of PIMs to 18.89%. Inappropriate medication use in geriatric patients remains high, and it is essential to improve patient education and enhance collaboration between pharmacists and doctors to reduce PIMs risks. The use of Beers, STOPP, and PRISCUS criteria can help assess and prevent PIMs in geriatric patients.
REVIEW: GAMBARAN TINGKAT KESALAHAN PENGOBATAN PADA BEBERAPA RUMAH SAKIT DI INDONESIA Adiningsih, Martha; Hermanto, Faizal
Jurnal Buana Farma Vol. 4 No. 4 (2024): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v4i4.1148

Abstract

A medication error is any preventable event that can cause or result in inappropriate medication use or harm to the patient. Medication errors can occur in several phases or stages, namely prescribing errors, errors in translating prescriptions, errors in preparing and dispensing drugs, and errors in administering drugs. The aim of this article is to review and identify various levels of medication errors in several hospitals in Indonesia which are obtained from the percentage of medication errors. Based on a literature review conducted on 10 journals, article searches were carried out using two databases, namely Google Schollar and PubMed, the results obtained were that the most common medication errors occurring in several hospitals in Indonesia were the prescribing phase with a total distribution of levels of 7, then dispensing with a count of 2 and copying with a count of 1. Although medication errors remain a major challenge, with appropriate improvement efforts, patient safety in hospitals can be significantly improved)
FORMULASI OBAT KUMUR EKSTRAK KULIT PISANG KEPOK KUNING (Musa paradisiaca L.) SEBAGAI ANTIBAKTERI Julyanti, Ai Rian; Genatrika, Erza; Annissya, Widia Primi; Setyaningrum, Nenden; Ferliati, Rosi Eka; Pratama, Okta Nurandi
Jurnal Buana Farma Vol. 4 No. 4 (2024): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v4i4.1151

Abstract

Yellow kepok banana peel (Musa paradisiaca L.) contains alkaloid, flavonoid, and tannin compounds that are known to have antibacterial activity. This study was conducted to determine the antibacterial activity of mouthwash from yellow kepok banana peel in inhibiting the growth of Streptococcus mutans. The yellow kepok banana peel used the maceration method with 96% ethanol solvent, then mouthwash preparation formulations with the extract concentrations of 2%, 4%, and 8%. The antibacterial activity of the mouthwash preparation was tested against Streptococcus mutans using the disc diffusion method. The results showed that the mouthwash formula of yellow kepok banana peel extract had inhibitory power on Streptococcus mutans bacteria with an inhibition zone of 9.52 mm in formula I, formula II 10.67 mm, and formula III 12.36 mm. Formulas I and II are classified as moderate antibacterial activity categories, while formula III is classified as having strong antibacterial activity. The results showed a p <0.05, meaning each test group has a significant difference. Formula III is the best formula because the resulting preparation is homogeneous, PH is 5, viscosity is 2.4 cP, the preparation is stable and formula III has the best antibacterial activity.
PENGARUH RESVERATROL TERHADAP JALUR PERMEABILITAS BARU SEBAGAI TARGET KERJA ANTIMALARIA Haq, Fahmy Ahsanul; Hermanto, Faizal; Sutjiatmo, Afifah Bambang; Lutfi, Mutiara Hadi
Jurnal Buana Farma Vol. 4 No. 4 (2024): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v4i4.1157

Abstract

Plasmodium is a parasite that causes malaria, which is transmitted to humans through the bite of female Anopheles mosquitoes. Plasmodium that infects red blood cells will cause the formation of new permeability pathway (NPP) in the red blood cell membrane. This change makes the red blood cell membrane more permeable, allowing various nutrients the parasite needs to enter the red blood cells. Resveratrol is a polyphenol compound that is reported to have antimalarial activity by inhibiting the growth of Plasmodium berghei. This study aims to activate the activity of resveratrol in inhibiting NPP. The study began with the preparation of blood suspensions that showed infection and non-infection, then test preparations were added and induced using sorbitol, and then hemolysis was measured using a UV-visible spectrophotometer. The test group consisted of normal groups, control and various concentrations of resveratrol, namely 1.25, 2.5, 5, 10 and 20 μM. The observation parameters in this study were the percentage of hemolysis inhibition. Based on the study’s results, the percentage of hemolysis inhibition increased with increasing resveratrol concentration. The IC50 value of the NPP inhibition activity test of resveratrol was 1.025 μM. This study concludes that resveratrol can inhibit NPP in erythrocytes infected with Plasmodium berghei.
EVALUASI TINGKAT KUALITAS KEPUASAN PASIEN PADA PELAYANAN INSTALASI FARMASI RUMAH SAKIT DIINDONESIA (Narrative Review) Sukma, Sischa Milara; Wahyuningsih, Sri
Jurnal Buana Farma Vol. 4 No. 4 (2024): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v4i4.1167

Abstract

Good quality standards for health services are a level of perfection in health services, giving rise to a feeling of satisfaction in patients. This means that the more perfect the patient's satisfaction, the better the quality of health services. The aim of this review is to determine the level of patient satisfaction in hospital pharmacy installation services in Indonesia and to find out what factors influence the level of patient satisfaction in hospital pharmacy installations. . This review uses a narrative review which uses articles or journals published in 2014 -2024. The literature sources were obtained from the Google Scholar and Pud Med websites, namely 10 journals and were included in the inclusion criteria. The results obtained show that the friendliness of the staff, speed in administering medication, and comfortable facilities and infrastructure can increase patient satisfaction. In conclusion, the level of patient satisfaction is a reflection of the level of satisfaction in health services. The level of patient satisfaction is influenced by many factors, including the provision of drug information, the timeliness of drug administration services, the friendly attitude of staff, and the comfort of facilities and infrastructure which can increase patient satisfaction. Assessment of the quality of patient satisfaction services covers five main dimensions including: physical evidence, reliability, responsiveness, assurance and empathy.
PEMANFAATAN BAWANG MERAH DAN KULIT BUAH NAGA SEBAGAI UJI DETEKSI BORAKS DAN FORMALIN PADA MAKANAN YANG BEREDAR DI SALAH SATU PASAR TRADISIONAL KOTA BANDUNG Nursamtari, Raden Ajeng; Rahmadewi, Yulia
Jurnal Buana Farma Vol. 4 No. 4 (2024): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v4i4.1168

Abstract

The lack of awareness of producers in adding dangerous preservatives such as borax and formaldehyde to food for sale on the market is a threat to society. Both ingredients are prohibited for human consumption because they can endanger health. Shallots and dragon fruit skin are believed to be able to detect borax and formaldehyde content in food because both ingredients contain anthocyanin compounds which are part of flavonoids. The aim of this research is to find out how to carry out a borax and formalin detection test by using red onions and dragon fruit skin and to find out whether there is borax and formalin content in food circulating in one of the traditional markets in Bandung. This research is experimental research. The sampling technique used was purposive sampling. The samples used were food circulating in one of the traditional markets in Bandung. Based on the research results, it was found that red onion extract (Allium cepa L.) and dragon fruit (Hylocereus polyrhizus) peel extract positively contained flavonoids. In addition, 3 out of 10 food samples tested positive for formalin and 10 out of 10 food samples did not contain borax. This can be seen through the color change that occurs in the test sample solution. Based on the research results, it can be concluded that red onion extract and dragon fruit peel extract can be effectively used to identify borax and formaldehyde content in food

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