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Hanif Amrulloh
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Journal of Multidisciplinary Applied Natural Science
Published by Pandawa Institute
ISSN : -     EISSN : 27743047     DOI : 10.47352/jmans
Core Subject : Science, Education, Agriculture, Social, Engineering,
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Energy Environmental Science Immunology & microbiology Materials Science & Nanotechnology Mathematics Physics
Journal of Multidisciplinary Applied Natural Science (abbreviated as J. Multidiscip. Appl. Nat. Sci.) is a double-blind peer-reviewed journal for multidisciplinary research activity on natural sciences and their application on daily life. This journal aims to make significant contributions to applied research and knowledge across the globe through the publication of original, high-quality research articles in the following fields: 1) biology and environmental science 2) chemistry and material sciences 3) physical sciences and 4) mathematical sciences. The J. Multidiscip. Appl. Nat. Sci. is an open-access journal containing original research articles, review articles, and short communications in the areas related to applied natural science. The J. Multidiscip. Appl. Nat. Sci. publishes 2 issues in a year on January (first issue) and July (second issue). This journal has adopted a double-blind reviewing policy whereby both the referees and author(s) remain anonymous throughout the process.
Arjuna Subject : Umum - Umum
Articles 133 Documents
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Influence of Water Table and Peat Thickness on Dissolved Organic Carbon of Tropical Peat Soil with Sulfidic Substratum from Central Kalimantan, Indonesia Zafrullah Damanik; Adi Jaya; Bostang Radjagukguk; Chaidir Adam
Journal of Multidisciplinary Applied Natural Science Vol. 4 No. 1 (2024): Journal of Multidisciplinary Applied Natural Science
Publisher : Pandawa Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47352/jmans.2774-3047.189

Abstract

Peatlands are important due to their high carbon storage, their role in suppressing climate change processes, and their importance for local and global communities’ livelihood. Large amounts of organic carbon pools in peatlands can be released into the environment as gaseous emitted carbon and lost through waterways (fluvial). The carbon released through the water stream consists of organic and inorganic forms and is partly in the form of CO2 and CH4 gases. The organic form consists of dissolved organic carbon (DOC) and particulate organic carbon, where DOC is the most dominant organic carbon in water sourced from peatlands. This research's objectives were to study the DOC concentration of peat water resulting from the hydrological condition's difference and the peat thickness overlaying the sulfidic substratum. The study was carried out in the Pangkoh area of Pulang Pisau district of Central Kalimantan. Peat water is taken on PVC pipes installed on each plot representing different peat thicknesses (deep, moderate, and shallow peat) at a depth of 25, 50, 100, 150, 200, and 250 cm from the soil surface. The water sampling was conducted on the peak wet season, during the transition from wet season to dry season and during the peak dry season. The results showed that DOC was influenced by peat thickness, depth of sulfidic material, and groundwater level. The release of DOC is higher from the deep peat than from the thin and moderate peat. The difference in DOC concentration between peat thickness is also related to the electrical conductivity of the peat water. The results showed a negative correlation between electrical conductivity and DOC concentration. The negative correlation was significant in the observation of the rainy and dry seasons, while in the transitional season, it was not significant.
Fixed Point Theorems for Semigroups of Lipschitzian Mappings Saiful Marom; Muhammad Istiqlal
Journal of Multidisciplinary Applied Natural Science Vol. 4 No. 1 (2024): Journal of Multidisciplinary Applied Natural Science
Publisher : Pandawa Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47352/jmans.2774-3047.191

Abstract

The main purpose of this paper is to extend the results of fixed point theorems for lipschitzian semigroups. The proofs we give follow the results of Ishihara, Suantai and Puengrattana theorems. Using one of the proofs, we also develop a fixed point theorem result for nonempty asymptotically total mapping semigroups on uniformly convex Banach spaces.
Enhancing Photocatalytic Activity of Bismuth Ferrite (BiFeO3) via Gadolinium and Copper Doping: A Sol-Gel Synthesis and Characterization Study Beerelli Rajitha; Padma Suvarna
Journal of Multidisciplinary Applied Natural Science Vol. 4 No. 1 (2024): Journal of Multidisciplinary Applied Natural Science
Publisher : Pandawa Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47352/jmans.2774-3047.192

Abstract

In this current research work, the sol-gel method was employed to synthesise, characterize and evaluate the photocatalytic activity of bismuth ferrite (BiFeO3, BFO) doped with two distinctive components consisting of a rare earth element Gadolinium (Gd) and a transition metal Copper (Cu). The dopant concentrations were systematically varied with different weight percentages (wt.%) denoted as Bi1-xGdxFe1-yCuyO3 (where ‘x’ = 0.10, 0.15 and 0.20 wt.%, where ‘y’ = 0.05, 0.10, and 0.15 wt.%). Subsequently, characterizations of the prepared samples were conducted using an array of cutting-edge analytical techniques including X-ray diffraction (XRD), filed emission scanning electron microscopy (FE-SEM), energy dispersive X-ray analysis (EDAX), and transmission electron microscopy (TEM). The XRD analysis results indicated that the presence of small impurity peaks was found in both Gd-doped BFO and GdCu-doped BFO. The FE-SEM and TEM results provided confirmation that the material was observed as a spherical shape, and the elemental compositions were also confirmed through EDAX analysis. The photocatalytic degradation of Rhodamine B dye under the influence of visible light irradiation was carried out and the results revealed varying degradation times, specifically, for Gd and Cu-doped BFO (Gd and Cu = 0.1 wt.%) achieved almost 98% degradation occurred in 30 minutes.
Advancing Green Nanotechnology: Harnessing the Bio-reducing Properties of Musa paradisiaca Peel Extract for Sustainable Synthesis of Iron Oxide Nanoparticles Esther Uwidia Ikhuoria; Ita Erebho Uwidia; Rachel Obhade Okojie; Ikhazuagbe Hilary Ifijen; Ikechukwu Dorris Chikaodili; Awalul Fatiqin
Journal of Multidisciplinary Applied Natural Science Vol. 4 No. 1 (2024): Journal of Multidisciplinary Applied Natural Science
Publisher : Pandawa Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47352/jmans.2774-3047.194

Abstract

A green synthesis method utilizing Musa paradisiaca peel extract as a reducing and stabilizing agent was employed to produce iron oxide nanoparticles. The synthesized nanoparticles were extensively characterized using FTIR, XRD, DLS, SEM, EDX, and TEM techniques. FTIR analysis confirmed the presence of iron metal and functional groups derived from the peel extract. XRD results indicated the presence of magnetite (Fe3O4) and/or maghemite (γ-Fe2O3) phases, signifying a high degree of crystallinity. DLS analysis provided valuable insights into the size distribution and polydispersity of the nanoparticles, revealing an average particle diameter of 43.35 nm and a polydispersity index of 0.612. SEM examination uncovered the presence of aggregated formations, where irregularly shaped nanoparticles exhibited either close packing or loose association, resulting in the formation of larger aggregates. These environmentally friendly iron oxide nanoparticles could potentially hold great promise for a variety of biological applications, including the potential for drug delivery and antimicrobial applications.
Impact of Feed Point Position on Patch Antenna’s Return Loss and Bandwidth for UWB Applications Md. Firoz Ahmed; Md. Hasnat Kabir; Abu Zafor Md. Touhidul Islam
Journal of Multidisciplinary Applied Natural Science Vol. 4 No. 1 (2024): Journal of Multidisciplinary Applied Natural Science
Publisher : Pandawa Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47352/jmans.2774-3047.158

Abstract

The demand for compact, lightweight, and high-performance antennas has increased in recent times in the communication industry. Microstrip patch antenna (MPA) becomes a better choice to effectively fulfill these requirements. In this study, hybrid techniques of partial ground plane, slotted patch, and defective ground structure are employed in MPA design to reduce the return loss, good impedance matching, and increased the bandwidth, gain, and efficiency of the antenna. This research demonstrates the impact of altering the feed point position, a crucial phenomenon of antenna design, on the patch antenna and determines the proper feed point location by comparing a minimum return loss (S11) which achieves the highest performance for the designed antenna. High-frequency structure simulator (HFSS) software is used to design and simulate the patch antenna. The operating frequency of the antenna is 6.85 GHz for UWB applications (3.1–10.6 GHz). A FR4 epoxy substrate material with dimensions of 30 mm × 20 mm is used to design the antenna. It has a dielectric constant of 4.4, a thickness of 0.8 mm and a tangent loss of 0.02. Multiple resonant frequencies are observed with different return losses for each feed location. The analysis shows that the finest feeding point is found at the center of the patch (9, 0) with a very low return loss (-28.35 dB), and a high impedance bandwidth (19.7 GHz). The antenna also achieved a gain of 4.46 dB, a directivity of 4.6904 dB, and a radiation efficiency of 95.90%. Hence, the location of the feed point can be considered as an influential factor in the antenna design.
Evaluation of The Anticancer Activity of Hydroxyxanthones Against Human Liver Carcinoma Cell Line Yehezkiel Steven Kurniawan; Nela Fatmasari; Jumina Jumina; Harno Dwi Pranowo; Eti Nurwening Sholikhah
Journal of Multidisciplinary Applied Natural Science Vol. 4 No. 1 (2024): Journal of Multidisciplinary Applied Natural Science
Publisher : Pandawa Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47352/jmans.2774-3047.165

Abstract

Nowadays, cancer is one of the most fatal diseases in developed and developing countries. Therefore, it is an urgent need to find more effective anticancer drugs among the recent commercially available standard drugs. Xanthone derivatives have been researched as anticancer drugs due to their ease of synthesis and structure modification, as well as their excellent anticancer activity. In this work, the in vitro anticancer activity of hydroxyxanthones against the human liver carcinoma cell line (HepG2) was evaluated. Among the twenty-two hydroxyxanthones, 1,3,6,8-tetrahydroxyxanthone was found as the most active anticancer agent with an IC50 value of 9.18 μM, which was better than doxorubicin as the standard drug. From the molecular docking studies against topoisomeraseIIα and two c-KIT protein kinases, 1,3,6,8-tetrahydroxyxanthone yielded strong binding energy in a range of -25.48 to -30.42 kJ/mol. The 1,3,6,8-tetrahydroxyxanthone could bind on the active site of these protein receptors through hydrogen bonds with key amino acid residues (Glu640, Cys673, Gln767, Met769, Asp810, and Asp831), as well as nitrogen bases (Adenine12 and Guanine13), thus leading to the death of HepG2 cancer cells through the apoptosis mechanism.
Cytotoxic Activity of Green Seaweed Halimeda tuna Methanolic Extract Against Lung Cancer Cells Amir Husni; Mohamad Gazali; Nurjanah Nurjanah; Rina Syafitri; Abdul Matin; Zuriat Zuriat
Journal of Multidisciplinary Applied Natural Science Vol. 4 No. 1 (2024): Journal of Multidisciplinary Applied Natural Science
Publisher : Pandawa Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47352/jmans.2774-3047.172

Abstract

Lung cancer is a malignant tumor that attacks the lungs generated by carcinogenic free radicals such as cigarette smoke. Seaweed contains bioactive compounds that have the potential to reduce cancer-causing free radicals. This study aimed to determine the phytochemical content and cytotoxic activity of Halimeda tuna seaweed extract against lung cancer cells (A549). The H. tuna sample was macerated using methanol for 24 h. Cytotoxic test of H. tuna crude extract used the MTT test against A549. The crude extract was phytochemically tested and analyzed using gas chromatography–mass spectrometry (GC-MS). The results showed that the H. tuna crude extract had cytotoxic activity against A549 with an IC50 value of 2771 µg/mL. The phytochemical test showed that H. tuna crude extract contained flavonoids and steroids. showed the presence of fatty acid compounds including palmitic acid, oleic acid, myristic acid, palmitoleic acid and stearic acid. Based on the results can be concluded that H. tuna extract had cytotoxic activity against A549 with low cytotoxicity to be used as a chemo-preventive agent.
The Potential of Moringa Leaf Nanoparticles (Moringa oleifera) on the Expression of TNFα, IL10, and HSP 27 in Oral Cavity Cancer Theresia Indah Budhy; Deddy Adam; Zulikran Moh Rizki Azis; Vania Syahputri; M Gandul Atik Yuliani; Muhammad Febriano Sugiarso Suwarto; Fery Setiawan
Journal of Multidisciplinary Applied Natural Science Vol. 4 No. 1 (2024): Journal of Multidisciplinary Applied Natural Science
Publisher : Pandawa Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47352/jmans.2774-3047.198

Abstract

Oral cancer is currently the sixth leading malignancy in the world, with over 330,000 cases resulting in death. Several cytokines and proteins protect the survival of cancer cells, such as TNF-α, HSP27, and IL-10. Moringa oleifera is an herbal medicine with anti-cancer properties. Nanoparticles of M. oleifera have the property to be easily absorbed by water-soluble cells, so only small doses are needed to be used as anti-cancer ingredients. This research aims to prove the ability of M. oleifera nanoparticle extract against oral cancer through the expression of tumour necrosis factor α (TNF-α), heat shock protein (HSP27), and interleukin 10 (IL-10). Rat as non-human experimental subjects were divided into four groups: control group (K), treatment group 1 (P1), treatment group 2 (P2), and treatment group 3 (P3). Cancer induction was carried out by injecting with benzo[a]pyrene, and then M. oleifera nanoparticle extract was administered in three forms of treatment doses of 125 μg/mL (P1), 250 μg/mL (P2), and 500 μg/mL (P3). Immunohistochemical examination was analysed through TNF-α, HSP27, and IL-10’s expression. The expression of TNF-α and HSP27 between control and treatment groups was significantly different. P2 had the lowest expression of TNF-α and HSP27. The expression of IL-10 between control and treatment groups was also significantly different. P1 had the lowest expression of IL-10. M. oleifera nanoparticle extract can reduce oral cancer progression by decreasing the expression of TNF-α, HSP27, and IL-10.
Evaluation of The Integrated Protocol for The Management of Severe Malnutrition in Children at The National Hospital of Nouakchott-Mauritania Sima Boulebatt Mahfoud; Hamid El Oirdi; El Hafedh El Mouhab; Nasser Abdellahi; Feil Ahmed; Jaouad Mostafi; Manal Maaroufi; Saïd Lotfi; Khadija El Kharrim; Driss Belghyti
Journal of Multidisciplinary Applied Natural Science Vol. 4 No. 1 (2024): Journal of Multidisciplinary Applied Natural Science
Publisher : Pandawa Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47352/jmans.2774-3047.199

Abstract

Malnutrition is a worldwide concern with worrisome outcomes that affect substantially the lifestyle of infants. The main aim is to investigate the efficacy of the IMSAM protocol over malnourished Mauritanian children during hospitalization. A cohort of 230 participants, including 126 boys and 104 girls collected from rural and urban areas with an average age of 15.52 ± 7.727 months were enrolled. The study is carried out in the Pediatric Service of the National Hospital Center of Nouakchott, Mauritania on children who have undergone the national protocol for the Integrated Management of Severe Acute Malnutrition (IMSAM). In addition, the medical and nutritional treatment, and body measurements were appreciated as well as the anthropometric parameters. The findings exhibit during nutritional-based intervention significant differences between the mean of weight during the pre- and post-intervention (P < 0.001). Moreover, through a regression test, we found a negatively predicted weight gain (P < 0.05) by the variables Z-score of weight to height (P / T) Edema after Nutritional Support and final health status. Last, but by no means least, the IMSAM-based intervention with rational management might make inroads into mitigating adverse outcomes of malnutrition through maximizing social skills.
Antioxidant and Antibacterial Activities of Curd and Whey Kefir Produced from Etawa Goat Milk Siwi Meutia Sadewi; Nurhasanah Nurhasanah; Sudibyo Sudibyo; Neneng Windayani; Agung Abadi Kiswandono; Heri Satria
Journal of Multidisciplinary Applied Natural Science Vol. 4 No. 1 (2024): Journal of Multidisciplinary Applied Natural Science
Publisher : Pandawa Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47352/jmans.2774-3047.200

Abstract

Kefir is a fermented drink with many benefits. Kefir contains antioxidant compounds that can inhibit free radical activity.In addition, kefir contains lactic acid bacteria, which provide good antibacterial activity and improve the health of the digestive tract. This research aimed to determine the antioxidant and antibacterial activities of kefir made from Etawa goat milk. The methods used in this research included fermentation of Etawa goat milk with 10 % kefir seeds at 37 °C and a fermentation time of 2 days. Antioxidant activity was tested using 1,1-diphenyl-2-picrylhydrazyl (DPPH), and antibacterial activity was tested using agar diffusion. The peptide molecular weights in kefir were analyzed using SDS-PAGE. The results showed that the antibacterial and antioxidant activities in Etawa goat's milk curd kefir has a higher activity than whey kefir. The antioxidant activity of curd has an IC50 of 43.99 ppm, which is a powerful antioxidant. Curd's antibacterial activity forms a clear zone of 7 mm against Bacillus cereus and is included in the solid antibacterial category. In Escherichia coli, a clear zone of 6 mm was formed and included in the moderate antibacterial category. The results of SDS-PAGE gel visualization found three prominent bands measuring 10, 15, and 33 kDa, respectively.

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