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Studi Literatur: Peran Apoteker dalam Pengawasan Keamanan Vaksin P dan M di Indonesia Reyhan Diva Zaafira; Windy Amelia; Revita Fitri Amelia; Rosa Adelina
Pharmaceutical and Biomedical Sciences Journal (PBSJ) Vol 4, No 1 (2022)
Publisher : UIN Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/pbsj.v4i1.24398

Abstract: Coronavirus disease (COVID-19) has infected millions of people globally since the World Health Organization declared a pandemic on March 11, 2020. Various efforts have been made to control the COVID-19 pandemic, including the development of vaccines. Pfizer and Moderna vaccines are mRNA-based vaccines developed in Indonesia with promising safety and effectiveness. The method used in this research is a descriptive method using literature studies in journals that discuss the safety control of P and M vaccines in Indonesia, with work procedures that include literature search, literature selection, literature documentation, analysis, and drawing conclusions. The results of the literature study show that pharmacists play an important role in maintaining the safety, quality, and efficacy of vaccines starting from the selection and procurement of distribution (which includes storage) to the time of use. At the selection stage, pharmacists must be able to consider the policies of international and national organizations. Pharmacists are fully responsible for procurement by ensuring that the vaccines received meet the standards and have a certificate of release from the competent authority of the country where the vaccine was released as well as a summary protocol issued by the manufacturer. Pharmacists are also responsible for distribution by keeping the COVID-19 vaccine within the specified temperature range. In use, pharmacists play a role in ensuring that vaccines are given according to the rules and in post-vaccination Monitoring of Drug Side Effects.

Aplikasi FTIR sebagai Deteksi Cepat Bahan Non-Halal dalam Campuran Produk Olahan Mabrurotul Mustafidah; Arif Nur Ikhsan
Pharmaceutical and Biomedical Sciences Journal (PBSJ) Vol 4, No 1 (2022)
Publisher : UIN Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/pbsj.v4i1.24426

The trend of Halal is not about label processed products, but also to become a necessity in products to gain public trust. Indonesia as the country with the most Muslims in Asia, has its own market for halal products. Consumer confidence increases for goods that have included halal in their products. The unknown material in this case is the material that makes the product non-halal, such as the presence of a mixture of pork. Many irresponsible producers use a mixture of non-halal ingredients to increase profits. To detect halal, various methods have been developed, one of which is FTIR. FTIR is a fast and easy to use instrument capable of analyzing mixtures in a product. Various studies for product authentication were analyzed using FTIR and showed results that FTIR was able to detect the presence of a mixture of unwanted ingredients in the product and could be used as a method to detect counterfeiters in processed products.

The Development of Derivative Method analysis 1,4 Benzodiazepines in Biological Matrix using High-Performance Liquid Chromatography (HPLC) and Liquid Chromatography-Mass Annisa Larasati Putri; supandi supandi; Umar Mansur
Pharmaceutical and Biomedical Sciences Journal (PBSJ) Vol 4, No 1 (2022)
Publisher : UIN Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/pbsj.v4i1.24629

1.4 benzodiazepine derivatives are the benzodiazepine class that is used most frequently in clinical as a sedation agent, anxiolytic, and antiepileptic. The high tense of benzodiazepine consumption can causes addiction and misappropriation. That matter causes benzodiazepine and its metabolites often find in toxicology clinical and forensic. This systematic review aimed to identify an efficient sample preparation procedure and an accurate analysis method to determine benzodiazepine existence in various biological matrices. According to the PRISMA flow diagram’s chart, twenty-four reviewed articles systematically pointed that plasma and urine utilization gave good accuracy results and recovery than other biological matrices. SBSE extraction method development using vinylpyrrolidone ethylene glycol dimethacrylate polymer gave efficient results with the amount of recovery 96%, and HPLC instrument utilization was still selective and sensitive with LOD until 12ng/ml and LOQ 36 ng/ml.

Pengaruh Penambahan Enhancer Isopropil Miristat dan dan Propilen Glikol terhadap Penetrasi Krim Asiklovir Estu Mahanani Dhilasari
Pharmaceutical and Biomedical Sciences Journal (PBSJ) Vol 4, No 1 (2022)
Publisher : UIN Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/pbsj.v4i1.25859

Acyclovir, a BCS class III drug, has a high ability to fight the herpes virus but has low permeability and is poorly soluble in water. In order to obtain the expected effect of viral infection on the skin, the penetration of the active ingredients becomes a critical factor for a topical treatment to achieve the desired concentration. This study was to see the effect of adding isopropyl myristate and propylene glycol as enhancers that help diffuse the drug through the stratum corneum. The formulation is made by adding enhancer propylene glycol 8% (F1), isopropyl myristate 8% (F2), and without enhancers (F3). Physical stability of acyclovir cream, including homogeneity, organoleptic, pH, viscosity, type of emulsion and power spread, and in vitro cream penetration test with Franz diffusion cells will be observed. The result of acyclovir cream preparations F1, F2, and F3 had a homogeneous preparation of white semisolid and odorless with pH between 7,30-7,60, emulsion type o/w, and a viscosity between 35000-47000 cPS. The cumulative amount of acyclovir penetrated at F3 was 226,008± 8,462 μg/cm2, while the cream containing the enhancers F1 258,059±1,730 μg/cm2 and F2 268,336±0,740 μg/cm2, respectively. The presence of enhancers will increase the penetration ability of acyclovir cream, with more penetration using isopropyl myristate than propylene glycol.

Analisis Hubungan Petugas Apotek Terhadap Pelayanan Informasi Obat Kontrasepsi Oral Marvel Marvel
Pharmaceutical and Biomedical Sciences Journal (PBSJ) Vol 4, No 1 (2022)
Publisher : UIN Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/pbsj.v4i1.28108

The successful implementation of the Family Planning (Keluarga Berencana) program assists the government in developing reproductive health. The acceptors' knowledge about oral contraceptive drugs may be influenced by drug information conveyed by pharmacy staff, namely pharmacists and their assistants. Therefore, this study aimed to measure relationship between pharmacy staff and information services for oral contraceptives at the South Tangerang Regional Pharmacy using a cross-sectional design. This study used trained simulated patients. The samples surveyed were 152 pharmacies with 132 pharmaceutical technical personnel, and 20 pharmacists as respondent. In terms of drug information services, this study found 94 subjects in the poor category (value of 69.9%), 44 subjects (26.4%) in the moderate category (value between 70-79.9%), and 14 subjects (7.9%) in the good category (value of 80%). There was a significant relationship between the pharmacy staff variable with the total value of drug information services (Pelayanan Informasi Obat) variable (p = 0.016). The result showed that pharmacists provide information services for oral contraceptives better than pharmacy technicians.

Analysis of Escherichia coli Microbial Contamination and Total Coliform Bacteria in Refill Drinking Water in Pondok Cabe Ilir Village, South Tangerang City Puteri Amelia; Ummi Habibah; Ofa Suzanti Betha
Pharmaceutical and Biomedical Sciences Journal (PBSJ) Vol 4, No 1 (2022)
Publisher : UIN Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/pbsj.v4i1.24699

Water is an essential nutrient for human health. It is important to maintain adequate drinking water intake to prevent dehydration, which can cause hypothermia, dizziness, constipation, and kidney stones. Currently, water-filling stations are an alternative source of drinking water because of limited access to clean water at affordable prices. The purpose of this study was to determine bacterial contamination at a drinking water station in Pondok Cabe Ilir, South Tangerang, Banten, based on Permenkes RI No. 492/Menkes/Per/IV/2010. The study was conducted using the Most Probable Number (MPN) method and the IMViC test, Triple Sugar Iron test, H2S production test, and motility test to identify Escherichia coli. The results showed that one out of five refilled drinking water samples contained Coliform bacteria above the threshold according to Minister of Health Regulation No. 492/Menkes/Per/IV/2010.

The Development of Derivative Method analysis 1,4 Benzodiazepines in Biological Matrix using High-Performance Liquid Chromatography (HPLC) and Liquid Chromatography-Mass Annisa Larasati Putri; supandi supandi; Umar Mansur
Pharmaceutical and Biomedical Sciences Journal (PBSJ) Vol 4, No 1 (2022)
Publisher : UIN Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/pbsj.v4i1.24629

1.4 benzodiazepine derivatives are the benzodiazepine class that is used most frequently in clinical as a sedation agent, anxiolytic, and antiepileptic. The high tense of benzodiazepine consumption can causes addiction and misappropriation. That matter causes benzodiazepine and its metabolites often find in toxicology clinical and forensic. This systematic review aimed to identify an efficient sample preparation procedure and an accurate analysis method to determine benzodiazepine existence in various biological matrices. According to the PRISMA flow diagram’s chart, twenty-four reviewed articles systematically pointed that plasma and urine utilization gave good accuracy results and recovery than other biological matrices. SBSE extraction method development using vinylpyrrolidone ethylene glycol dimethacrylate polymer gave efficient results with the amount of recovery 96%, and HPLC instrument utilization was still selective and sensitive with LOD until 12ng/ml and LOQ 36 ng/ml.

Pengaruh Penambahan Enhancer Isopropil Miristat dan dan Propilen Glikol terhadap Penetrasi Krim Asiklovir Estu Mahanani Dhilasari
Pharmaceutical and Biomedical Sciences Journal (PBSJ) Vol 4, No 1 (2022)
Publisher : UIN Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/pbsj.v4i1.25859

Acyclovir, a BCS class III drug, has a high ability to fight the herpes virus but has low permeability and is poorly soluble in water. In order to obtain the expected effect of viral infection on the skin, the penetration of the active ingredients becomes a critical factor for a topical treatment to achieve the desired concentration. This study was to see the effect of adding isopropyl myristate and propylene glycol as enhancers that help diffuse the drug through the stratum corneum. The formulation is made by adding enhancer propylene glycol 8% (F1), isopropyl myristate 8% (F2), and without enhancers (F3). Physical stability of acyclovir cream, including homogeneity, organoleptic, pH, viscosity, type of emulsion and power spread, and in vitro cream penetration test with Franz diffusion cells will be observed. The result of acyclovir cream preparations F1, F2, and F3 had a homogeneous preparation of white semisolid and odorless with pH between 7,30-7,60, emulsion type o/w, and a viscosity between 35000-47000 cPS. The cumulative amount of acyclovir penetrated at F3 was 226,008± 8,462 μg/cm2, while the cream containing the enhancers F1 258,059±1,730 μg/cm2 and F2 268,336±0,740 μg/cm2, respectively. The presence of enhancers will increase the penetration ability of acyclovir cream, with more penetration using isopropyl myristate than propylene glycol.

Analisis Hubungan Petugas Apotek Terhadap Pelayanan Informasi Obat Kontrasepsi Oral Marvel Marvel
Pharmaceutical and Biomedical Sciences Journal (PBSJ) Vol 4, No 1 (2022)
Publisher : UIN Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/pbsj.v4i1.28108

The successful implementation of the Family Planning (Keluarga Berencana) program assists the government in developing reproductive health. The acceptors' knowledge about oral contraceptive drugs may be influenced by drug information conveyed by pharmacy staff, namely pharmacists and their assistants. Therefore, this study aimed to measure relationship between pharmacy staff and information services for oral contraceptives at the South Tangerang Regional Pharmacy using a cross-sectional design. This study used trained simulated patients. The samples surveyed were 152 pharmacies with 132 pharmaceutical technical personnel, and 20 pharmacists as respondent. In terms of drug information services, this study found 94 subjects in the poor category (value of 69.9%), 44 subjects (26.4%) in the moderate category (value between 70-79.9%), and 14 subjects (7.9%) in the good category (value of 80%). There was a significant relationship between the pharmacy staff variable with the total value of drug information services (Pelayanan Informasi Obat) variable (p = 0.016). The result showed that pharmacists provide information services for oral contraceptives better than pharmacy technicians.

Analysis of Escherichia coli Microbial Contamination and Total Coliform Bacteria in Refill Drinking Water in Pondok Cabe Ilir Village, South Tangerang City Puteri Amelia; Ummi Habibah; Ofa Suzanti Betha
Pharmaceutical and Biomedical Sciences Journal (PBSJ) Vol 4, No 1 (2022)
Publisher : UIN Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/pbsj.v4i1.24699

Water is an essential nutrient for human health. It is important to maintain adequate drinking water intake to prevent dehydration, which can cause hypothermia, dizziness, constipation, and kidney stones. Currently, water-filling stations are an alternative source of drinking water because of limited access to clean water at affordable prices. The purpose of this study was to determine bacterial contamination at a drinking water station in Pondok Cabe Ilir, South Tangerang, Banten, based on Permenkes RI No. 492/Menkes/Per/IV/2010. The study was conducted using the Most Probable Number (MPN) method and the IMViC test, Triple Sugar Iron test, H2S production test, and motility test to identify Escherichia coli. The results showed that one out of five refilled drinking water samples contained Coliform bacteria above the threshold according to Minister of Health Regulation No. 492/Menkes/Per/IV/2010.

Home Page

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Reviewer

Google Scholar

Contact Name
Ismiarni Komala

Contact Email
pbsj@uinjkt.ac.id

Phone
+6282125509705

Journal Mail Official
pbsj@uinjkt.ac.id

Editorial Address
Program Studi Farmasi, Fakultas Ilmu Kesehatan UIN Syarif Hidayatullah Jakarta Jl. Kertamukti No. 5, Pisangan, Ciputat 15412 Tangerang Selatan, Banten, Indonesia Telp: (62-21)74716718 Fax: (62-21) 7404985

Location
Kota tangerang selatan,

Banten

INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name Ismiarni Komala

Contact Email pbsj@uinjkt.ac.id

Phone +6282125509705

Journal Mail Official pbsj@uinjkt.ac.id

Editorial Address Program Studi Farmasi, Fakultas Ilmu Kesehatan UIN Syarif Hidayatullah Jakarta Jl. Kertamukti No. 5, Pisangan, Ciputat 15412 Tangerang Selatan, Banten, Indonesia Telp: (62-21)74716718 Fax: (62-21) 7404985

Location Kota tangerang selatan, Banten INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Contact Name
Ismiarni Komala

Contact Email
pbsj@uinjkt.ac.id

Phone
+6282125509705

Journal Mail Official
pbsj@uinjkt.ac.id

Editorial Address
Program Studi Farmasi, Fakultas Ilmu Kesehatan UIN Syarif Hidayatullah Jakarta Jl. Kertamukti No. 5, Pisangan, Ciputat 15412 Tangerang Selatan, Banten, Indonesia Telp: (62-21)74716718 Fax: (62-21) 7404985

Location
Kota tangerang selatan,

Banten

INDONESIA